Published in Eukaryot Cell on February 21, 2014
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need. Nat Rev Microbiol (2017) 1.38
Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes. Nat Protoc (2014) 0.82
A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens. Acta Crystallogr D Biol Crystallogr (2015) 0.77
Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases. Biochimie (2014) 0.76
Novel Effects of Lapatinib Revealed in the African Trypanosome using Hypothesis-Generating Proteomics and Chemical Biology Strategies. Antimicrob Agents Chemother (2016) 0.75
Chemogenetic Characterization of Inositol Phosphate Metabolic Pathway Reveals Druggable Enzymes for Targeting Kinetoplastid Parasites. Cell Chem Biol (2016) 0.75
Evolution and Application of Inteins in Candida species: A Review. Front Microbiol (2016) 0.75
The druggable genome. Nat Rev Drug Discov (2002) 13.61
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol (1999) 11.77
Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication. Acta Trop (1979) 8.43
Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem (1999) 6.54
High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome. Genome Res (2011) 4.09
Kinetoplastids: related protozoan pathogens, different diseases. J Clin Invest (2008) 3.59
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei. Science (2001) 3.52
Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. Cell (2012) 3.38
Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov (2008) 2.58
RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei. Mol Biochem Parasitol (2003) 2.55
Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites. Nucleic Acids Res (2010) 2.38
The A-Z of bacterial translation inhibitors. Crit Rev Biochem Mol Biol (2009) 2.34
On the evolution of structure in aminoacyl-tRNA synthetases. Microbiol Mol Biol Rev (2003) 2.22
Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin. Cell Host Microbe (2012) 2.05
Target assessment for antiparasitic drug discovery. Trends Parasitol (2007) 1.96
A comprehensive analysis of Trypanosoma brucei mitochondrial proteome. Proteomics (2009) 1.94
Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness). Lancet Neurol (2012) 1.82
The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J Biol Chem (2004) 1.75
Evolution and relatedness in two aminoacyl-tRNA synthetase families. Proc Natl Acad Sci U S A (1991) 1.60
Aspartyl-tRNA synthetase is the target of peptide nucleotide antibiotic Microcin C. J Biol Chem (2006) 1.59
NECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sickness. PLoS Negl Trop Dis (2010) 1.55
State of the art in African trypanosome drug discovery. Curr Top Med Chem (2011) 1.53
Development of novel drugs for human African trypanosomiasis. Future Microbiol (2011) 1.44
Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice. Antimicrob Agents Chemother (2011) 1.37
Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization. J Med Chem (2012) 1.35
Regulated expression of an essential allosteric activator of polyamine biosynthesis in African trypanosomes. PLoS Pathog (2008) 1.25
Dual targeting of a single tRNA(Trp) requires two different tryptophanyl-tRNA synthetases in Trypanosoma brucei. Proc Natl Acad Sci U S A (2006) 1.23
Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection. Structure (2012) 1.18
Structural switch of lysyl-tRNA synthetase between translation and transcription. Mol Cell (2012) 1.17
TDR Targets: a chemogenomics resource for neglected diseases. Nucleic Acids Res (2011) 1.15
Mitochondrial tRNA import--the challenge to understand has just begun. Biol Chem (2009) 1.13
The 14-3-3 proteins of Trypanosoma brucei function in motility, cytokinesis, and cell cycle. J Biol Chem (2005) 1.13
Structural diversity and protein engineering of the aminoacyl-tRNA synthetases. Biochemistry (2012) 1.13
ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase. Nature (2012) 1.13
Aminoacyl-tRNA synthetase inhibitors as potential antibiotics. Eur J Med Chem (2011) 1.12
Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: synthesis, molecular docking and structure-activity relationship analysis of 3-aryl-4-arylaminofuran-2(5H)-ones. Eur J Med Chem (2011) 1.12
Selection of reference genes for mRNA quantification in Trypanosoma brucei. Mol Biochem Parasitol (2010) 1.11
A potent seryl tRNA synthetase inhibitor SB-217452 isolated from a Streptomyces species. J Antibiot (Tokyo) (2000) 1.05
Mitochondrial translation is essential in bloodstream forms of Trypanosoma brucei. Mol Microbiol (2010) 1.05
Coupling of posterior cytoskeletal morphogenesis to the G1/S transition in the Trypanosoma brucei cell cycle. Mol Biol Cell (2004) 1.03
Non-canonical eukaryotic glutaminyl- and glutamyl-tRNA synthetases form mitochondrial aminoacyl-tRNA in Trypanosoma brucei. J Biol Chem (2003) 1.03
A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases. J Biol Chem (2004) 1.02
Dual targeting of aminoacyl-tRNA synthetases to the apicoplast and cytosol in Plasmodium falciparum. Int J Parasitol (2011) 1.02
Dual targeting of a tRNAAsp requires two different aspartyl-tRNA synthetases in Trypanosoma brucei. J Biol Chem (2009) 1.01
Inhibition of methionyl-tRNA synthetase by REP8839 and effects of resistance mutations on enzyme activity. Antimicrob Agents Chemother (2008) 1.01
In vivo study in Trypanosoma brucei links mitochondrial transfer RNA import to mitochondrial protein import. EMBO Rep (2011) 0.99
Design, synthesis, and structure-activity relationship of Trypanosoma brucei leucyl-tRNA synthetase inhibitors as antitrypanosomal agents. J Med Chem (2011) 0.99
SB-219383, a novel tyrosyl tRNA synthetase inhibitor from a Micromonospora sp. II. Structure determination. J Antibiot (Tokyo) (2000) 0.98
Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs. J Mol Biol (2010) 0.97
Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment. Proc Natl Acad Sci U S A (2012) 0.95
A Gateway® compatible vector for gene silencing in bloodstream form Trypanosoma brucei. Mol Biochem Parasitol (2011) 0.94
Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. Bioorg Med Chem Lett (2005) 0.94
Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. J Biol Chem (2002) 0.93
Dual targeting of isoleucyl-tRNA synthetase in Trypanosoma brucei is mediated through alternative trans-splicing. Nucleic Acids Res (2011) 0.93
Aminoacyl-tRNA synthetase inhibitors as antimicrobial agents: a patent review from 2006 till present. Expert Opin Ther Pat (2012) 0.90
Mutational analysis of Trypanosoma brucei editosome proteins KREPB4 and KREPB5 reveals domains critical for function. RNA (2012) 0.90
A spectrophotometric assay for quantitative measurement of aminoacyl-tRNA synthetase activity. J Biomol Screen (2012) 0.89
Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J Med Chem (2013) 0.89
Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia. Invest New Drugs (2011) 0.89
Unusual domain architecture of aminoacyl tRNA synthetases and their paralogs from Leishmania major. BMC Genomics (2012) 0.89
Synthesis of beta-ketophosphonate analogs of glutamyl and glutaminyl adenylate, and selective inhibition of the corresponding bacterial aminoacyl-tRNA synthetases. Bioorg Med Chem (2006) 0.87
A mechanism for functional segregation of mitochondrial and cytosolic genetic codes. Proc Natl Acad Sci U S A (2009) 0.86
Amplification of the gene for isoleucyl-tRNA synthetase facilitates adaptation to the fitness cost of mupirocin resistance in Salmonella enterica. Genetics (2010) 0.85
A multiple aminoacyl-tRNA synthetase complex that enhances tRNA-aminoacylation in African trypanosomes. Mol Cell Biol (2013) 0.85
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans. Antimicrob Agents Chemother (2004) 0.84
Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase. Mol Biochem Parasitol (2011) 0.84
Partition of aminoacyl-tRNA synthetases in two different structural classes dating back to early metabolism: implications for the origin of the genetic code and the nature of protein sequences. J Mol Evol (1995) 0.84
Identification of Trypanosoma brucei leucyl-tRNA synthetase inhibitors by pharmacophore- and docking-based virtual screening and synthesis. Bioorg Med Chem (2011) 0.82
Amino-acyl tRNA synthetases generate dinucleotide polyphosphates as second messengers: functional implications. Top Curr Chem (2014) 0.82
Confirmation of the antibacterial mode of action of SB-219383, a novel tyrosyl tRNA synthetase inhibitor from a Micromonospora sp. J Antibiot (Tokyo) (2002) 0.82
Further characterization of Bacillus subtilis antibiotic biosensors and their use for antibacterial mode-of-action studies. Antimicrob Agents Chemother (2011) 0.80
Mitochondrial translation in trypanosomatids: a novel target for chemotherapy? Trends Parasitol (2011) 0.79
Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human African Trypanosomiasis. J Biol Chem (2013) 0.78
Influence of ochratoxin B on the ochratoxin A inhibition of phenylalanyl-tRNA formation in vitro and protein synthesis in hepatoma tissue culture cells. Toxicol Lett (1989) 0.77
Borrelidin, a potent antifungal agent: insight into the antifungal mechanism against Phytophthora sojae. J Agric Food Chem (2012) 0.77
The mechanism of inhibition of valyl-tRNA synthetase by S-adenosylhomocysteine. Biochim Biophys Acta (1982) 0.76
SB-203207 and SB-203208, two novel isoleucyl tRNA synthetase inhibitors from a Streptomyces sp. II. Structure determination. J Antibiot (Tokyo) (2000) 0.76
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (2005) 7.61
Chemical genetics of Plasmodium falciparum. Nature (2010) 5.52
Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature (2004) 4.35
Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region. Mol Cell (2003) 2.54
Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat Struct Mol Biol (2010) 2.34
Identification of novel components of Trypanosoma brucei editosomes. RNA (2003) 2.30
Mechanisms of action of external volume expansion devices. Plast Reconstr Surg (2013) 2.22
Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei. BMC Genomics (2009) 2.00
Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. J Infect Dis (2007) 1.99
An essential RNase III insertion editing endonuclease in Trypanosoma brucei. Proc Natl Acad Sci U S A (2005) 1.96
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential. J Med Chem (2011) 1.94
Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol Cell (2003) 1.94
TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosome. Mol Cell (2003) 1.88
RNA editing in Trypanosoma brucei requires three different editosomes. Mol Cell Biol (2007) 1.87
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice. J Med Chem (2009) 1.87
Protein kinases as drug targets in trypanosomes and Leishmania. Biochim Biophys Acta (2005) 1.87
Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation. Hum Reprod (2008) 1.79
High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. J Biol Chem (2005) 1.73
Transcription initiation and termination on Leishmania major chromosome 3. Eukaryot Cell (2004) 1.67
TbMP81 is required for RNA editing in Trypanosoma brucei. EMBO J (2002) 1.65
RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei. J Biol Chem (2004) 1.58
A deletion site editing endonuclease in Trypanosoma brucei. Mol Cell (2005) 1.57
Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity. J Med Chem (2012) 1.56
Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol (2008) 1.56
Role of uridylate-specific exoribonuclease activity in Trypanosoma brucei RNA editing. Eukaryot Cell (2002) 1.55
Primary intraosseous squamous cell carcinoma of the jaws. Clinicopathologic presentation and prognostic factors. Arch Pathol Lab Med (2009) 1.54
State of the art in African trypanosome drug discovery. Curr Top Med Chem (2011) 1.53
Comparative analysis of editosome proteins in trypanosomatids. Nucleic Acids Res (2003) 1.52
An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae. J Biol Chem (2009) 1.46
Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. J Biol Chem (2010) 1.46
Product feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozyme. Mol Microbiol (2013) 1.45
Shotgun optical mapping of the entire Leishmania major Friedlin genome. Mol Biochem Parasitol (2004) 1.45
Trypanosoma brucei mitochondrial ribosomes: affinity purification and component identification by mass spectrometry. Mol Cell Proteomics (2008) 1.44
Features of the K-complex waves in refractory nocturnal frontal lobe epilepsy. Epilepsy Res (2010) 1.42
Allosteric regulation of an essential trypanosome polyamine biosynthetic enzyme by a catalytically dead homolog. Proc Natl Acad Sci U S A (2007) 1.41
Single-base resolution maps of cultivated and wild rice methylomes and regulatory roles of DNA methylation in plant gene expression. BMC Genomics (2012) 1.40
TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei. Eukaryot Cell (2003) 1.39
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes. Proc Natl Acad Sci U S A (2008) 1.37
Characterization of protein kinase CK2 from Trypanosoma brucei. Mol Biochem Parasitol (2006) 1.37
Gene synteny and evolution of genome architecture in trypanosomatids. Mol Biochem Parasitol (2004) 1.36
Mass spectrometric analysis of the editosome and other multiprotein complexes in Trypanosoma brucei. J Am Soc Mass Spectrom (2003) 1.35
The NOG1 GTP-binding protein is required for biogenesis of the 60 S ribosomal subunit. J Biol Chem (2003) 1.33
Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J Biol Chem (2009) 1.32
Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity. J Biol Chem (2002) 1.29
Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study. Obesity (Silver Spring) (2013) 1.28
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice. J Med Chem (2011) 1.28
Regulated expression of an essential allosteric activator of polyamine biosynthesis in African trypanosomes. PLoS Pathog (2008) 1.25
Glucose is toxic to glycosome-deficient trypanosomes. Proc Natl Acad Sci U S A (2002) 1.25
Asexual populations of the human malaria parasite, Plasmodium falciparum, use a two-step genomic strategy to acquire accurate, beneficial DNA amplifications. PLoS Pathog (2013) 1.25
Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection. Mol Biochem Parasitol (2011) 1.24
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies. Mol Microbiol (2008) 1.22
Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation. Anticancer Res (2008) 1.21
Cell cycle-regulated vesicular trafficking of Toxoplasma APT1, a protein localized to multiple apicoplast membranes. Mol Microbiol (2007) 1.20
KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2006) 1.19
RNA sequence and base pairing effects on insertion editing in Trypanosoma brucei. Mol Cell Biol (2002) 1.15
KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2007) 1.14
The 14-3-3 proteins of Trypanosoma brucei function in motility, cytokinesis, and cell cycle. J Biol Chem (2005) 1.13
Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei. Int J Parasitol (2008) 1.13
Analysis of flavin oxidation and electron-transfer inhibition in Plasmodium falciparum dihydroorotate dehydrogenase. Biochemistry (2008) 1.13
Palladium-catalyzed picolinamide-directed alkylation of unactivated C(sp3)-H bonds with alkyl iodides. J Am Chem Soc (2013) 1.12
Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1. Bioorg Med Chem Lett (2012) 1.12
Impact of newly diagnosed breast cancer on quality of life among Chinese women. Breast Cancer Res Treat (2006) 1.11
Paramecium bursaria chlorella virus-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylases. J Biol Chem (2004) 1.10
A thioredoxin family protein of the apicoplast periphery identifies abundant candidate transport vesicles in Toxoplasma gondii. Eukaryot Cell (2008) 1.10
Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme. J Biol Chem (2003) 1.09
Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway. PLoS One (2013) 1.08
Interleukin 10 rs1800872 T>G polymorphism was associated with an increased risk of esophageal cancer in a Chinese population. Asian Pac J Cancer Prev (2013) 1.08
An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei. RNA (2007) 1.08
Species specificity in ribosome biogenesis: a nonconserved phosphoprotein is required for formation of the large ribosomal subunit in Trypanosoma brucei. Eukaryot Cell (2005) 1.07
Endonuclease associations with three distinct editosomes in Trypanosoma brucei. J Biol Chem (2011) 1.07
Differential functions of two editosome exoUases in Trypanosoma brucei. RNA (2009) 1.06
Risk score for the prediction of contrast-induced nephropathy in elderly patients undergoing percutaneous coronary intervention. Angiology (2012) 1.06
Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases. J Biol Chem (2007) 1.05
Kinetoplastid RNA editing ligases: complex association, characterization, and substrate requirements. Mol Biochem Parasitol (2003) 1.05
Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis. Antimicrob Agents Chemother (2009) 1.03
Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice. Am J Physiol Gastrointest Liver Physiol (2011) 1.03
Transgenic complementation of leptin receptor deficiency. II. Increased leptin receptor transgene dose effects on obesity/diabetes and fertility/lactation in lepr-db/db mice. Am J Physiol Endocrinol Metab (2003) 1.03
Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study. Am J Epidemiol (2013) 1.03
Identification of essential and non-essential protein kinases by a fusion PCR method for efficient production of transgenic Trypanosoma brucei. Mol Biochem Parasitol (2013) 1.02
Proteome analysis of human androgen-independent prostate cancer cell lines: variable metastatic potentials correlated with vimentin expression. Proteomics (2007) 1.01
Endoribonuclease activities of Trypanosoma brucei mitochondria. Mol Biochem Parasitol (2002) 1.00
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. FASEB J (2013) 1.00
Identification of rhizome-specific genes by genome-wide differential expression analysis in Oryza longistaminata. BMC Plant Biol (2011) 0.99
In vitro engineering of human ear-shaped cartilage assisted with CAD/CAM technology. Biomaterials (2009) 0.99
Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H bonds with primary alkyl halides. J Am Chem Soc (2013) 0.98
Long-term ginsenoside consumption prevents memory loss in aged SAMP8 mice by decreasing oxidative stress and up-regulating the plasticity-related proteins in hippocampus. Brain Res (2008) 0.98
RNA interference-mediated silencing of ornithine decarboxylase and spermidine synthase genes in Trypanosoma brucei provides insight into regulation of polyamine biosynthesis. Eukaryot Cell (2009) 0.98
Chronic ethanol consumption alters mammalian gastrointestinal content metabolites. J Proteome Res (2013) 0.97
A membrane protease is targeted to the relict plastid of toxoplasma via an internal signal sequence. Traffic (2007) 0.97
Dissection of brefeldin A-sensitive and -insensitive steps in apicoplast protein targeting. J Cell Sci (2005) 0.97
Analysis of elite variety tag SNPs reveals an important allele in upland rice. Nat Commun (2013) 0.97
X-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibility. J Biol Chem (2003) 0.97
Genetic diversity and haplotype structure of 24 Y-chromosomal STR in Chinese Hui ethnic group and its genetic relationships with other populations. Electrophoresis (2014) 0.97
Probing the role of compartmentation of glycolysis in procyclic form Trypanosoma brucei: RNA interference studies of PEX14, hexokinase, and phosphofructokinase. J Biol Chem (2005) 0.97
Fluorine modulates species selectivity in the triazolopyrimidine class of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors. J Med Chem (2014) 0.96
Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase. Biochemistry (2006) 0.96
Changes of organic anion transporter MRP4 and related nuclear receptors in human obstructive cholestasis. J Gastrointest Surg (2011) 0.96
X-ray structure of Paramecium bursaria Chlorella virus arginine decarboxylase: insight into the structural basis for substrate specificity. Biochemistry (2007) 0.95
Evolution and multifarious horizontal transfer of an alternative biosynthetic pathway for the alternative polyamine sym-homospermidine. J Biol Chem (2010) 0.95