Published in Acta Med Okayama on June 01, 1988
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med (2001) 16.51
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A (2001) 11.06
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature (2001) 11.03
Transducing fragments in generalized transduction by phage P1. I. Molecular origin of the fragments. J Mol Biol (1965) 7.72
The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. Surg Gynecol Obstet (1967) 7.24
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev (2001) 6.15
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature (1994) 5.33
Prophage P1, and extrachromosomal replication unit. Cold Spring Harb Symp Quant Biol (1968) 4.75
Cell surface antigens of human malignant melanoma: definition of six antigenic systems with mouse monoclonal antibodies. Proc Natl Acad Sci U S A (1980) 4.66
Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature (1997) 4.57
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites. Proc Natl Acad Sci U S A (2001) 4.56
Changes in expression of murine leukemia virus antigens and production of xenotropic virus in the late preleukemic period in AKR mice. Proc Natl Acad Sci U S A (1976) 4.52
Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation (2001) 4.01
The preparation and testing of horse antidog and antihuman antilymphoid plasma or serum and its protein fractions. Surg Gynecol Obstet (1967) 3.86
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest (1998) 3.76
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest (1993) 3.57
Kabuki make-up syndrome: a syndrome of mental retardation, unusual facies, large and protruding ears, and postnatal growth deficiency. J Pediatr (1981) 3.55
Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Nature (1990) 3.23
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc Natl Acad Sci U S A (1998) 3.14
Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor. Nature (1982) 3.09
Relation of GIX antigen of thymocytes to envelope glycoprotein of murine leukemia virus. J Exp Med (1975) 3.06
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes (2000) 3.01
Application of colorimetric microdilution plate hybridization for rapid genetic identification of 22 Mycobacterium species. J Clin Microbiol (1991) 2.98
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest (2000) 2.96
Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5. Mol Cell Biol (1998) 2.91
Myeloscopy, with special reference to blood flow changes in the cauda equina during Lasègue's test. Int Orthop (1981) 2.82
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Eradication of established tumors by CD8+ T cell adoptive immunotherapy. Immunity (2000) 2.81
Efficacy and safety of adeno-associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy. J Thromb Haemost (2006) 2.81
Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition. Antimicrob Agents Chemother (1994) 2.76
The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes Dev (1998) 2.75
Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75
Chromatographic separation and antigenic analysis of proteins of the oncornaviruses. V. Identification of a new murine viral protein, p15(E). J Virol (1975) 2.72
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J Biol Chem (2001) 2.69
Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis. J Biol Chem (1998) 2.51
Rice dwarf mutant d1, which is defective in the alpha subunit of the heterotrimeric G protein, affects gibberellin signal transduction. Proc Natl Acad Sci U S A (2000) 2.51
RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli. Proc Natl Acad Sci U S A (1997) 2.51
Purification and characterization of DNA topoisomerase IV in Escherichia coli. J Biol Chem (1992) 2.50
Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell (1994) 2.48
Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene. Antimicrob Agents Chemother (1996) 2.42
Expression of functional acetylcholine receptor from cloned cDNAs. Nature (1984) 2.41
Location of functional regions of acetylcholine receptor alpha-subunit by site-directed mutagenesis. Nature (1985) 2.40
Identification and partial characterization of Mycobacterium avium and Mycobacterium intracellulare by using DNA probes. J Clin Microbiol (1989) 2.37
Submucosal endoscopic tumor resection for subepithelial tumors in the esophagus and cardia. Endoscopy (2012) 2.32
Fractionated stereotactic radiotherapy for choroidal melanoma. Radiother Oncol (1997) 2.29
Conditional clara cell ablation reveals a self-renewing progenitor function of pulmonary neuroendocrine cells. Am J Physiol Lung Cell Mol Physiol (2000) 2.28
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature (1997) 2.20
Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes (1999) 2.19
Age-related changes in cell surface antigens of preleukemic AKR thymocytes. J Exp Med (1976) 2.15
Suppression of the heterotrimeric G protein causes abnormal morphology, including dwarfism, in rice. Proc Natl Acad Sci U S A (1999) 2.15
Tracheal lidocaine attenuates the cardiovascular response to endotracheal intubation. Can J Anaesth (2001) 2.10
Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2. J Biol Chem (1995) 2.09
Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine. Blood (1992) 2.06
A sharp peak of the zero-temperature penetration depth at optimal composition in BaFe2(As(1-x)P(x))2. Science (2012) 2.05
Production of 'hybrid' antibiotics by genetic engineering. Nature (1985) 2.04
High dose rate brachytherapy for carcinoma of the uterine cervix: comparison of two different fractionation regimens. Int J Radiat Oncol Biol Phys (1995) 2.02
Autosomal dominant moyamoya disease maps to chromosome 17q25.3. Neurology (2008) 2.00
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes. J Clin Invest (2001) 1.97
Illegitimate recombination mediated in vitro by DNA gyrase of Escherichia coli: structure of recombinant DNA molecules. Proc Natl Acad Sci U S A (1982) 1.97
Comparison of the sensitivity of NAT using pooled donor samples for HBV and that of a serologic HBsAg assay. Transfusion (2001) 1.97
Frequent presence of anti-GQ1b antibody in Fisher's syndrome. Neurology (1993) 1.96
Eyelid reconstruction using a hard palate mucoperiosteal graft combined with a V-Y subcutaneously pedicled flap. Br J Plast Surg (2001) 1.96
Biological expression of antigenic determinants of murine leukemia virus proteins gp69-71 and p30. J Virol (1974) 1.95
Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans. J Nutr (2000) 1.95
Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice. Mol Cell Biol (1996) 1.95
Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains. Oncogene (1988) 1.95
Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Circulation (2001) 1.92
Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes. J Am Coll Cardiol (1998) 1.91
The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun (2000) 1.91
In vitro study of illegitimate recombination: involvement of DNA gyrase. Cold Spring Harb Symp Quant Biol (1981) 1.90
Diversity of immunodominant 56-kDa type-specific antigen (TSA) of Rickettsia tsutsugamushi. Sequence and comparative analyses of the genes encoding TSA homologues from four antigenic variants. J Biol Chem (1992) 1.87
Characterization of a molecularly cloned retroviral sequence associated with Fv-4 resistance. J Virol (1985) 1.87
The rubble-pile asteroid Itokawa as observed by Hayabusa. Science (2006) 1.87
Serological survey of normal humans for natural antibody to cell surface antigens of melanoma. Proc Natl Acad Sci U S A (1980) 1.86
Ascorbic acid inhibits antitumor activity of bortezomib in vivo. Leukemia (2009) 1.84
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes. Diabetologia (2002) 1.83
Acute cervical cord injury without fracture or dislocation of the spinal column. J Neurosurg (2000) 1.75
Quartz crystal microbalance for the detection of microgram quantities of human serum albumin: relationship between the frequency change and the mass of protein adsorbed. Anal Chem (1993) 1.73
A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. N Engl J Med (1994) 1.72
Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: can acetazolamide test predict it? Stroke (2001) 1.71
Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro. Proc Natl Acad Sci U S A (1988) 1.70
GENESIS, a knowledge-based genetic engineering simulation system for representation of genetic data and experiment planning. Nucleic Acids Res (1982) 1.70
Why do phospholipid polymers reduce protein adsorption? J Biomed Mater Res (1998) 1.70
Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J Clin Invest (1997) 1.69
Genetic mapping, cloning and physiological aspects of the glucose kinase gene of Streptomyces coelicolor. Mol Gen Genet (1984) 1.67
Endoscopic partial resection of a duodenal duplication cyst. Endoscopy (2001) 1.67
Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover. J Clin Invest (2000) 1.67
Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments. Exp Cell Res (1990) 1.66
Prevalence of K329E mutation in medium-chain acyl-CoA dehydrogenase gene determined from Guthrie cards. Lancet (1991) 1.66
Hypoxic brain damage: cortical laminar necrosis and delayed changes in white matter at sequential MR imaging. Radiology (1993) 1.65
Tissue-specific suppressor T cells involved in self-tolerance are activated extrathymically by self-antigens. Immunology (1994) 1.65
Involvement of DNA-dependent RNA polymerase in a recA-independent pathway of genetic recombination in Escheria coli. Proc Natl Acad Sci U S A (1977) 1.63
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest (1997) 1.63
Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation. Mol Cell Biol (2001) 1.62
Urinary chiro-inositol excretion is an index marker of insulin sensitivity in Japanese type II diabetes. Diabetes Care (1994) 1.62
Inflammatory pseudotumor of the liver: case report and review of the literature. J Pediatr Surg (2001) 1.61
Alcohol consumption appears to protect against non-alcoholic fatty liver disease. Aliment Pharmacol Ther (2010) 1.60
Cloning and sequencing of the gene (tsg56) encoding a type-specific antigen from Rickettsia tsutsugamushi. Gene (1990) 1.60
Circulating vascular cell adhesion molecule-1 (VCAM-1) in atherosclerotic NIDDM patients. Diabetes (1997) 1.60