Lewis Whitehead

Author PubWeight™ 11.89^‹?›

Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Discovery of LFF571: an investigational agent for Clostridium difficile infection.	J Med Chem	2012	1.26
2	Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics.	J Biol Chem	2014	1.03
3	An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential.	J Cheminform	2011	0.86
4	Avoidance of the Ames test liability for aryl-amines via computation.	Bioorg Med Chem	2011	0.84
5	Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.	J Med Chem	2011	0.84
6	Atomic-scale characterization of conformational changes in the preQ₁ riboswitch aptamer upon ligand binding.	J Mol Graph Model	2011	0.84
7	Identification of elongation factor G as the conserved cellular target of argyrin B.	PLoS One	2012	0.83
8	Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway.	Bioorg Med Chem Lett	2012	0.83
9	The chemical tuning of a weak zinc binding motif for histone deacetylase using electronic effects.	Chem Biol Drug Des	2012	0.80
10	Automated ligand- and structure-based protocol for in silico prediction of human serum albumin binding.	J Chem Inf Model	2013	0.78
11	Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.	J Med Chem	2011	0.78
12	The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.	Bioorg Med Chem Lett	2011	0.76
13	Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824).	J Med Chem	2010	0.76
14	Antibacterial and Solubility Optimization of Thiomuracin A.	J Med Chem	2016	0.75
15	Application of non-parametric regression to quantitative structure-activity relationships.	Bioorg Med Chem	2002	0.75