Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model.

PubWeight™: 2.59‹?› | Rank: Top 1%

🔗 View Article (PMC 247724)

Published in J Virol on February 01, 1989

Authors

C W Mandl1, F Guirakhoo, H Holzmann, F X Heinz, C Kunz

Author Affiliations

1: Institute of Virology, University of Vienna, Austria.

Articles citing this

Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell (2002) 9.13

The dengue viruses. Clin Microbiol Rev (1990) 4.72

Dengue virus structural differences that correlate with pathogenesis. J Virol (1999) 4.26

Mutational evidence for an internal fusion peptide in flavivirus envelope protein E. J Virol (2001) 3.58

Synthesis and secretion of recombinant tick-borne encephalitis virus protein E in soluble and particulate form. J Virol (1995) 2.97

Type- and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes. J Virol (2007) 2.89

Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein E. J Virol (1999) 2.87

Recombinant subviral particles from tick-borne encephalitis virus are fusogenic and provide a model system for studying flavivirus envelope glycoprotein functions. J Virol (1996) 2.75

Pestivirus glycoprotein which induces neutralizing antibodies forms part of a disulfide-linked heterodimer. J Virol (1990) 2.75

Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes. J Virol (2004) 2.64

Antibodies to envelope glycoprotein of dengue virus during the natural course of infection are predominantly cross-reactive and recognize epitopes containing highly conserved residues at the fusion loop of domain II. J Virol (2008) 2.39

Two hepatitis C virus glycoprotein E2 products with different C termini. J Virol (1994) 2.38

Detection by enzyme-linked immunosorbent assay of antibodies to West Nile virus in birds. Emerg Infect Dis (2002) 2.22

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2. J Virol (2010) 2.14

Processing of yellow fever virus polyprotein: role of cellular proteases in maturation of the structural proteins. J Virol (1989) 2.07

Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo. J Virol (2001) 1.94

The flavivirus envelope protein E: isolation of a soluble form from tick-borne encephalitis virus and its crystallization. J Virol (1991) 1.80

Molecular mechanisms of antibody-mediated neutralisation of flavivirus infection. Expert Rev Mol Med (2008) 1.67

Human monoclonal antibodies against West Nile virus induced by natural infection neutralize at a postattachment step. J Virol (2009) 1.65

Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4. Proc Natl Acad Sci U S A (1998) 1.60

Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein. J Virol (2004) 1.58

Antibody-mediated neutralization of flaviviruses: a reductionist view. Virology (2011) 1.48

Molecular epidemiology of dengue viruses in southern China from 1978 to 2006. Virol J (2011) 1.29

Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody. J Virol (2007) 1.28

Solution structure of the envelope protein domain III of dengue-4 virus. Virology (2007) 1.27

Probing the flavivirus membrane fusion mechanism by using monoclonal antibodies. J Virol (2007) 1.21

A single amino acid substitution in envelope protein E of tick-borne encephalitis virus leads to attenuation in the mouse model. J Virol (1990) 1.19

Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus. J Virol (2004) 1.19

Nucleotide sequence variation of the envelope protein gene identifies two distinct genotypes of yellow fever virus. J Virol (1995) 1.10

Serological differentiation of infections with dengue virus serotypes 1 to 4 by using recombinant antigens. J Clin Microbiol (2002) 1.07

Genetic and phenotypic characterization of sylvatic dengue virus type 2 strains. Virology (2008) 1.04

Use of recombinant E protein domain III-based enzyme-linked immunosorbent assays for differentiation of tick-borne encephalitis serocomplex flaviviruses from mosquito-borne flaviviruses. J Clin Microbiol (2004) 1.03

The complexity of antibody-dependent enhancement of dengue virus infection. Viruses (2010) 0.99

Differences in the postfusion conformations of full-length and truncated class II fusion protein E of tick-borne encephalitis virus. J Virol (2005) 0.99

Stereophysicochemical variability plots highlight conserved antigenic areas in Flaviviruses. Virol J (2005) 0.98

Impact of quaternary organization on the antigenic structure of the tick-borne encephalitis virus envelope glycoprotein E. J Virol (2009) 0.94

Attenuation of recombinant yellow fever 17D viruses expressing foreign protein epitopes at the surface. J Virol (2005) 0.92

T-helper cell and associated antibody response to synthetic peptides of the E glycoprotein of Murray Valley encephalitis virus. J Virol (1991) 0.88

Structure of yellow fever virus envelope protein domain III. Virology (2009) 0.87

A novel method for synthetic vaccine construction based on protein assembly. Sci Rep (2014) 0.84

Comparative analysis of full-length genomic sequences of 10 dengue serotype 1 viruses associated with different genotypes, epidemics, and disease severity isolated in Thailand over 22 years. Am J Trop Med Hyg (2010) 0.81

Possible future monoclonal antibody (mAb)-based therapy against arbovirus infections. Biomed Res Int (2013) 0.80

Reverse ELISA for the detection of anti West Nile virus IgG antibodies in humans. Eur J Clin Microbiol Infect Dis (2007) 0.80

Domain-based homology modeling and mapping of the conformational epitopes of envelope glycoprotein of west nile virus. J Mol Model (2005) 0.78

Aluminum hydroxide influences not only the extent but also the fine specificity and functional activity of antibody responses to tick-borne encephalitis virus in mice. J Virol (2013) 0.78

Immunoglobulin M enzyme-linked immunosorbent assay using recombinant polypeptides for diagnosis of dengue. Clin Diagn Lab Immunol (2005) 0.78

Actin Interacts with Dengue Virus 2 and 4 Envelope Proteins. PLoS One (2016) 0.77

The membrane-proximal "stem" region increases the stability of the flavivirus E protein postfusion trimer and modulates its structure. J Virol (2013) 0.77

Immunization with Immune Complexes Modulates the Fine Specificity of Antibody Responses to a Flavivirus Antigen. J Virol (2015) 0.76

The role of the poly(A) tract in the replication and virulence of tick-borne encephalitis virus. Sci Rep (2016) 0.75

Induction of neutralization antibodies in mice by Dengue-2 envelope DNA vaccines. P R Health Sci J (2009) 0.75

A novel mechanism of antibody-mediated enhancement of flavivirus infection. PLoS Pathog (2017) 0.75

A multiplex ELISA-based protein array for screening diagnostic antigens and diagnosis of Flaviviridae infection. Eur J Clin Microbiol Infect Dis (2015) 0.75

Articles cited by this

DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54

A simple method for displaying the hydropathic character of a protein. J Mol Biol (1982) 150.65

A simple and very efficient method for generating cDNA libraries. Gene (1983) 55.36

Maturation of the head of bacteriophage T4. I. DNA packaging events. J Mol Biol (1973) 33.51

The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem (1987) 11.99

Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science (1985) 8.54

3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors. Proc Natl Acad Sci U S A (1978) 6.67

The hydrophobic moment detects periodicity in protein hydrophobicity. Proc Natl Acad Sci U S A (1984) 6.36

Nucleotide sequence of dengue 2 RNA and comparison of the encoded proteins with those of other flaviviruses. Virology (1988) 4.78

Nucleotide sequence and deduced amino acid sequence of the structural proteins of dengue type 2 virus, Jamaica genotype. Virology (1986) 4.34

Nucleotide and complete amino acid sequences of Kunjin virus: definitive gene order and characteristics of the virus-specified proteins. J Gen Virol (1988) 4.09

Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins. J Mol Biol (1987) 4.07

Cloning full-length dengue type 4 viral DNA sequences: analysis of genes coding for structural proteins. Virology (1986) 3.85

Intrinsic and extrinsic factors in protein antigenic structure. Science (1985) 3.54

Continuous and discontinuous protein antigenic determinants. Nature (1986) 3.26

Sequence of the dengue-1 virus genome in the region encoding the three structural proteins and the major nonstructural protein NS1. Virology (1987) 3.05

An artificial anchor domain: hydrophobicity suffices to stop transfer. Cell (1985) 2.65

Sequence of the structural proteins of tick-borne encephalitis virus (western subtype) and comparative analysis with other flaviviruses. Virology (1988) 2.43

Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it. Proc Natl Acad Sci U S A (1987) 2.26

Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins. J Mol Biol (1986) 1.96

Protein antigenic structures recognized by T cells: potential applications to vaccine design. Immunol Rev (1987) 1.95

Homogeneity of the structural glycoprotein from European isolates of tick-borne encephalitis virus: comparison with other flaviviruses. J Gen Virol (1981) 1.90

Tick-borne encephalitis virus genome. The nucleotide sequence coding for virion structural proteins. FEBS Lett (1986) 1.74

Sequence analysis of the membrane protein V3 of the flavivirus West Nile virus and of its gene. Virology (1985) 1.72

Epitope mapping of flavivirus glycoproteins. Adv Virus Res (1986) 1.67

Analysis of disulfides present in the membrane proteins of the West Nile flavivirus. Virology (1987) 1.63

A topological and functional model of epitopes on the structural glycoprotein of tick-borne encephalitis virus defined by monoclonal antibodies. Virology (1983) 1.53

Antigenic structure and variation in an influenza virus N9 neuraminidase. J Virol (1987) 1.42

Partial nucleotide sequence of the Japanese encephalitis virus genome. Virology (1987) 1.39

Partial nucleotide sequence of St. Louis encephalitis virus RNA: structural proteins, NS1, ns2a, and ns2b. Virology (1987) 1.34

Partial nucleotide sequence and deduced amino acid sequence of the structural proteins of dengue virus type 2, New Guinea C and PUO-218 strains. J Gen Virol (1988) 1.25

Myristoylation and the post-translational acquisition of hydrophobicity by the membrane immunoglobulin heavy-chain polypeptide in B lymphocytes. Proc Natl Acad Sci U S A (1987) 1.17

Analysis of the influence of proteolytic cleavage on the structural organization of the surface of the West Nile flavivirus leads to the isolation of a protease-resistant E protein oligomer from the viral surface. Virology (1987) 1.11

Characterization of a disulphide bridge-stabilized antigenic domain of tick-borne encephalitis virus structural glycoprotein. J Gen Virol (1987) 1.10

Expression of Japanese encephalitis virus antigens in Escherichia coli. Virology (1987) 1.08

From the World Health Organization. Current approaches to the development of dengue vaccines and related aspects of the molecular biology of flaviviruses. J Infect Dis (1988) 1.08

Location of immunodominant antigenic determinants on fragments of the tick-borne encephalitis virus glycoprotein: evidence for two different mechanisms by which antibodies mediate neutralization and hemagglutination inhibition. Virology (1983) 1.06

Location of a neutralization determinant in the E protein of yellow fever virus (17D vaccine strain). Virology (1987) 1.02

Formation of polymeric glycoprotein complexes from a flavivirus: tick-borne encephalitis virus. J Gen Virol (1980) 1.02

Sequence of 3000 nucleotides at the 5' end of Japanese encephalitis virus RNA. Gene (1986) 0.91

Immunogenicity of tick-borne encephalitis virus glycoprotein fragments: epitope-specific analysis of the antibody response. J Gen Virol (1984) 0.81

Articles by these authors

The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature (1995) 12.25

Structural changes and functional control of the tick-borne encephalitis virus glycoprotein E by the heterodimeric association with protein prM. Virology (1994) 3.82

Proteolytic activation of tick-borne encephalitis virus by furin. J Virol (1997) 3.78

Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH. J Virol (1995) 3.67

Mutational evidence for an internal fusion peptide in flavivirus envelope protein E. J Virol (2001) 3.58

Cloning and expression of a chitinase gene from the hyperparasitic fungus Aphanocladium album. Curr Genet (1992) 3.24

Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus. Mol Cell (2001) 3.23

Synthesis and secretion of recombinant tick-borne encephalitis virus protein E in soluble and particulate form. J Virol (1995) 2.97

Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein E. J Virol (1999) 2.87

Recombinant subviral particles from tick-borne encephalitis virus are fusogenic and provide a model system for studying flavivirus envelope glycoprotein functions. J Virol (1996) 2.75

Sequencing the termini of capped viral RNA by 5'-3' ligation and PCR. Biotechniques (1991) 2.64

Sequence of the structural proteins of tick-borne encephalitis virus (western subtype) and comparative analysis with other flaviviruses. Virology (1988) 2.43

Fusion activity of flaviviruses: comparison of mature and immature (prM-containing) tick-borne encephalitis virions. J Gen Virol (1991) 2.34

Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus. J Virol (1996) 2.33

Tick-borne virus diseases of human interest in Europe. Clin Microbiol Infect (2004) 2.30

Sequence analysis and genetic classification of tick-borne encephalitis viruses from Europe and Asia. J Gen Virol (1999) 2.23

The phenomenon of treatment failures in Human African Trypanosomiasis. Trop Med Int Health (2001) 2.18

Epitope model of tick-borne encephalitis virus envelope glycoprotein E: analysis of structural properties, role of carbohydrate side chain, and conformational changes occurring at acidic pH. Virology (1989) 2.12

Spontaneous and engineered deletions in the 3' noncoding region of tick-borne encephalitis virus: construction of highly attenuated mutants of a flavivirus. J Virol (1998) 2.11

Membrane fusion activity of tick-borne encephalitis virus and recombinant subviral particles in a liposomal model system. Virology (2000) 2.09

The flavivirus 3'-noncoding region: extensive size heterogeneity independent of evolutionary relationships among strains of tick-borne encephalitis virus. Virology (1995) 2.08

Durability of SVR in chronic hepatitis C patients treated with peginterferon-α2a/ribavirin in combination with a direct-acting anti-viral. Aliment Pharmacol Ther (2013) 2.04

Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo. J Virol (2001) 1.94

Homogeneity of the structural glycoprotein from European isolates of tick-borne encephalitis virus: comparison with other flaviviruses. J Gen Virol (1981) 1.90

Flat Refractive Geometry. IEEE Trans Pattern Anal Mach Intell (2011) 1.90

The flavivirus envelope protein E: isolation of a soluble form from tick-borne encephalitis virus and its crystallization. J Virol (1991) 1.80

Infectious cDNA clones of tick-borne encephalitis virus European subtype prototypic strain Neudoerfl and high virulence strain Hypr. J Gen Virol (1997) 1.79

Attenuation of tick-borne encephalitis virus by structure-based site-specific mutagenesis of a putative flavivirus receptor binding site. J Virol (2000) 1.77

Genome sequence of tick-borne encephalitis virus (Western subtype) and comparative analysis of nonstructural proteins with other flaviviruses. Virology (1989) 1.76

In vitro-synthesized infectious RNA as an attenuated live vaccine in a flavivirus model. Nat Med (1998) 1.75

Recombinant, chimaeric live, attenuated vaccine (ChimeriVax) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates. Vaccine (1999) 1.70

Epitope mapping of flavivirus glycoproteins. Adv Virus Res (1986) 1.67

Chimeric yellow fever virus 17D-Japanese encephalitis virus vaccine: dose-response effectiveness and extended safety testing in rhesus monkeys. J Virol (2000) 1.64

Secondary structure of the 3'-noncoding region of flavivirus genomes: comparative analysis of base pairing probabilities. RNA (1997) 1.62

A model study of the use of monoclonal antibodies in capture enzyme immunoassays for antigen quantification exploiting the epitope map of tick-borne encephalitis virus. J Biol Stand (1986) 1.62

[Studies of the mechanism of the activity diminution of phosphoglucose isomerase in erythrocytes of patients with florid psoriasis vulgaris. I]. Arch Klin Exp Dermatol (1967) 1.61

Complete genomic sequence of Powassan virus: evaluation of genetic elements in tick-borne versus mosquito-borne flaviviruses. Virology (1993) 1.54

A topological and functional model of epitopes on the structural glycoprotein of tick-borne encephalitis virus defined by monoclonal antibodies. Virology (1983) 1.53

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in health care workers (HCWs): guidelines for prevention of transmission of HBV and HCV from HCW to patients. J Clin Virol (2003) 1.53

Establishment of PCR for the early diagnosis of herpes simplex encephalitis. J Med Virol (1990) 1.50

Laboratory findings in tick-borne encephalitis--correlation with clinical outcome. Infection (2000) 1.46

Loss of a histidine residue at the active site of S-locus ribonuclease is associated with self-compatibility in Lycopersicon peruvianum. Proc Natl Acad Sci U S A (1994) 1.46

Characterization of monoclonal antibody-escape mutants of tick-borne encephalitis virus with reduced neuroinvasiveness in mice. J Gen Virol (1997) 1.45

Detection of varicella-zoster virus DNA by polymerase chain reaction in the cerebrospinal fluid of patients suffering from neurological complications associated with chicken pox or herpes zoster. J Clin Microbiol (1991) 1.38

Human milk oligosaccharides are minimally digested in vitro. J Nutr (2000) 1.35

[Remarks on the stroma reaction in melanoma]. Med Welt (1967) 1.35

Safety and immunogenicity of an inactivated hepatitis A candidate vaccine in healthy adult volunteers. Vaccine (1990) 1.35

Correlation between ELISA, hemagglutination inhibition, and neutralization tests after vaccination against tick-borne encephalitis. J Med Virol (1996) 1.34

The envelope glycoproteins of dengue 1 and dengue 2 viruses grown in mosquito cells differ in their utilization of potential glycosylation sites. Virology (1994) 1.33

Molecular basis for attenuation of neurovirulence of a yellow fever Virus/Japanese encephalitis virus chimera vaccine (ChimeriVax-JE). J Virol (2001) 1.32

[Dehydroepiandrosterone deficiency in psoriasis. Hypothesis on the etiopathogenesis of this disease]. Hautarzt (1980) 1.31

Characterization and complete genome sequences of high- and low- virulence variants of tick-borne encephalitis virus. J Gen Virol (1996) 1.28

Studies with a cold-recombinant A/Victoria/3/75 (H3N2) virus. II. Evaluation in adult volunteers. J Infect Dis (1980) 1.27

Novel intranasal immunization techniques for antibody induction and protection of mice against gastric Helicobacter felis infection. Vaccine (1997) 1.26

Recombinant and virion-derived soluble and particulate immunogens for vaccination against tick-borne encephalitis. Vaccine (1995) 1.26

Reconstruction of orbital wall defects: critical review of 72 patients. Int J Oral Maxillofac Surg (2007) 1.24

Antibody-induced conformational changes result in enhanced avidity of antibodies to different antigenic sites on the tick-borne encephalitis virus glycoprotein. Virology (1984) 1.23

Role of metastability and acidic pH in membrane fusion by tick-borne encephalitis virus. J Virol (2001) 1.23

Expression of cloned envelope protein genes from the flavivirus tick-borne encephalitis virus in mammalian cells and random mutagenesis by PCR. Virus Genes (1994) 1.21

The interactions of the flavivirus envelope proteins: implications for virus entry and release. Arch Virol Suppl (1994) 1.20