Published in Mol Cell on March 01, 2001
Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell (2002) 9.13
A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc Natl Acad Sci U S A (2003) 7.76
Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme. Crit Rev Biochem Mol Biol (2008) 5.26
Structures of immature flavivirus particles. EMBO J (2003) 3.62
Mutational evidence for an internal fusion peptide in flavivirus envelope protein E. J Virol (2001) 3.58
Locations of carbohydrate sites on alphavirus glycoproteins show that E1 forms an icosahedral scaffold. Cell (2001) 2.96
Quantitative analysis of the hepatitis C virus replication complex. J Virol (2005) 2.91
Placement of the structural proteins in Sindbis virus. J Virol (2002) 2.81
West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. J Virol (2006) 2.79
A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus. Nat Immunol (2014) 2.34
Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites. J Virol (2006) 2.33
Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking. J Virol (2007) 2.03
Temperature dependent conformational change of dengue virus. Curr Opin Virol (2015) 1.98
Adaptation of tick-borne encephalitis virus to BHK-21 cells results in the formation of multiple heparan sulfate binding sites in the envelope protein and attenuation in vivo. J Virol (2001) 1.94
Solution structure of dengue virus capsid protein reveals another fold. Proc Natl Acad Sci U S A (2004) 1.85
West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody. Proc Natl Acad Sci U S A (2006) 1.83
Membrane interactions of the tick-borne encephalitis virus fusion protein E at low pH. J Virol (2002) 1.83
An external loop region of domain III of dengue virus type 2 envelope protein is involved in serotype-specific binding to mosquito but not mammalian cells. J Virol (2004) 1.81
Dengue structure differs at the temperatures of its human and mosquito hosts. Proc Natl Acad Sci U S A (2013) 1.75
Human monoclonal antibodies against West Nile virus induced by natural infection neutralize at a postattachment step. J Virol (2009) 1.65
Studying hepatitis C virus: making the best of a bad virus. J Virol (2007) 1.62
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis. Nat Rev Microbiol (2008) 1.60
Yellow Fever virus NS3 plays an essential role in virus assembly independent of its known enzymatic functions. J Virol (2008) 1.59
Characterization of the envelope glycoproteins associated with infectious hepatitis C virus. J Virol (2010) 1.59
Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc Natl Acad Sci U S A (2010) 1.57
Capsid protein C of tick-borne encephalitis virus tolerates large internal deletions and is a favorable target for attenuation of virulence. J Virol (2002) 1.48
Involvement of lipids in different steps of the flavivirus fusion mechanism. J Virol (2003) 1.42
Intracellular assembly and secretion of recombinant subviral particles from tick-borne encephalitis virus. J Virol (2003) 1.38
Hepatitis C virus envelope glycoprotein E2 glycans modulate entry, CD81 binding, and neutralization. J Virol (2007) 1.34
Lipids as modulators of membrane fusion mediated by viral fusion proteins. Eur Biophys J (2007) 1.29
Incorporation of tick-borne encephalitis virus replicons into virus-like particles by a packaging cell line. J Virol (2003) 1.28
Rapid development of a DNA vaccine for Zika virus. Science (2016) 1.27
Alterations of pr-M cleavage and virus export in pr-M junction chimeric dengue viruses. J Virol (2004) 1.27
Specific interaction of a novel foamy virus Env leader protein with the N-terminal Gag domain. J Virol (2001) 1.24
Capturing a flavivirus pre-fusion intermediate. PLoS Pathog (2009) 1.24
Mimicking live flavivirus immunization with a noninfectious RNA vaccine. Proc Natl Acad Sci U S A (2004) 1.23
Role of metastability and acidic pH in membrane fusion by tick-borne encephalitis virus. J Virol (2001) 1.23
Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assay. PLoS Negl Trop Dis (2012) 1.22
Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding. J Virol (2007) 1.21
Two distinct size classes of immature and mature subviral particles from tick-borne encephalitis virus. J Virol (2003) 1.17
Spontaneous mutations restore the viability of tick-borne encephalitis virus mutants with large deletions in protein C. J Virol (2003) 1.15
Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. PLoS One (2009) 1.13
Closing the door on flaviviruses: entry as a target for antiviral drug design. Antiviral Res (2008) 1.09
Protonation of individual histidine residues is not required for the pH-dependent entry of west nile virus: evaluation of the "histidine switch" hypothesis. J Virol (2009) 1.06
Molecular dissection of the Semliki Forest virus homotrimer reveals two functionally distinct regions of the fusion protein. J Virol (2002) 1.02
Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. J Biol Chem (2011) 1.02
Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease. Cell (2017) 1.01
Differentiation of West Nile and St. Louis encephalitis virus infections by use of noninfectious virus-like particles with reduced cross-reactivity. J Clin Microbiol (2007) 1.01
Aura virus structure suggests that the T=4 organization is a fundamental property of viral structural proteins. J Virol (2002) 1.00
The length of and nonhydrophobic residues in the transmembrane domain of dengue virus envelope protein are critical for its retention and assembly in the endoplasmic reticulum. J Virol (2010) 0.99
The pH sensor for flavivirus membrane fusion. J Cell Biol (2008) 0.98
N-linked glycans on dengue viruses grown in mammalian and insect cells. J Gen Virol (2009) 0.97
Role of the transmembrane domains of prM and E proteins in the formation of yellow fever virus envelope. J Virol (2003) 0.97
Isolation of capsid protein dimers from the tick-borne encephalitis flavivirus and in vitro assembly of capsid-like particles. J Virol (2004) 0.97
Functional requirements of the yellow fever virus capsid protein. J Virol (2007) 0.96
Structure of acidic pH dengue virus showing the fusogenic glycoprotein trimers. J Virol (2014) 0.95
Small-molecule inhibitors of dengue-virus entry. PLoS Pathog (2012) 0.94
The unique transmembrane hairpin of flavivirus fusion protein E is essential for membrane fusion. J Virol (2011) 0.94
Impact of quaternary organization on the antigenic structure of the tick-borne encephalitis virus envelope glycoprotein E. J Virol (2009) 0.94
Purification and crystallization reveal two types of interactions of the fusion protein homotrimer of Semliki Forest virus. J Virol (2004) 0.93
Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses. PLoS Pathog (2013) 0.92
Humoral and cellular immune response to RNA immunization with flavivirus replicons derived from tick-borne encephalitis virus. J Virol (2005) 0.90
The helical domains of the stem region of dengue virus envelope protein are involved in both virus assembly and entry. J Virol (2011) 0.87
Illustrating and homology modeling the proteins of the Zika virus. F1000Res (2016) 0.86
Characterization of the GXXXG motif in the first transmembrane segment of Japanese encephalitis virus precursor membrane (prM) protein. J Biomed Sci (2010) 0.86
A toggle switch controls the low pH-triggered rearrangement and maturation of the dengue virus envelope proteins. Nat Commun (2014) 0.86
Diagnosis of tick-borne encephalitis by a mu-capture immunoglobulin M-enzyme immunoassay based on secreted recombinant antigen produced in insect cells. J Clin Microbiol (2003) 0.86
The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry. Virology (2010) 0.86
Functional analysis of potential carboxy-terminal cleavage sites of tick-borne encephalitis virus capsid protein. J Virol (2007) 0.85
The transmembrane domains of the prM and E proteins of yellow fever virus are endoplasmic reticulum localization signals. J Virol (2004) 0.85
Protection of a single dose west nile virus recombinant subviral particle vaccine against lineage 1 or 2 strains and analysis of the cross-reactivity with Usutu virus. PLoS One (2014) 0.83
Single-dose vaccine against tick-borne encephalitis. Proc Natl Acad Sci U S A (2013) 0.83
Protein interactions during the flavivirus and hepacivirus life cycle. Mol Cell Proteomics (2017) 0.79
Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry. J Biol Chem (2014) 0.78
Virus-like particle secretion and genotype-dependent immunogenicity of dengue virus serotype 2 DNA vaccine. J Virol (2014) 0.77
Diagnostic potential and antigenic properties of recombinant tick-borne encephalitis virus subviral particles expressed in mammalian cells from Semliki Forest virus replicons. J Clin Microbiol (2013) 0.77
Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. J Gen Virol (2015) 0.77
The relationship between the structure of the tick-borne encephalitis virus strains and their pathogenic properties. PLoS One (2014) 0.76
Glutamic acid at residue 125 of the prM helix domain interacts with positively charged amino acids in E protein domain II for Japanese encephalitis virus-like-particle production. J Virol (2014) 0.76
Membrane Anchors of the Structural Flavivirus Proteins and Their Role in Virus Assembly. J Virol (2016) 0.76
Characterization of the disassembly and reassembly of the HBV glycoprotein surface antigen, a pliable nanoparticle vaccine platform. Virology (2017) 0.75
Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus. Sci Rep (2016) 0.75
Development of Virus like Particle Vaccine and Reporter Assay for Zika Virus. J Virol (2017) 0.75
Atomic structure of the ectodomain from HIV-1 gp41. Nature (1997) 16.31
The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature (1995) 12.25
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science (1998) 11.23
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet (2011) 10.62
Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials. Lancet (2011) 8.24
Three-dimensional structure of the tyrosine kinase c-Src. Nature (1997) 7.62
UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years. Lancet (2000) 7.19
Methods to increase response rates to postal questionnaires. Cochrane Database Syst Rev (2007) 7.13
Cell surface polarity in epithelia. Annu Rev Cell Biol (1985) 6.92
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex. Cell (1992) 6.47
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature (1995) 6.16
The T=4 envelope of Sindbis virus is organized by interactions with a complementary T=3 capsid. Cell (1987) 5.99
Structure of simian virus 40 at 3.8-A resolution. Nature (1991) 5.96
Structure of an IkappaBalpha/NF-kappaB complex. Cell (1998) 5.67
The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH. Cell (2001) 5.65
DNA recognition by GAL4: structure of a protein-DNA complex. Nature (1992) 5.60
Adding the third dimension to virus life cycles: three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs. Microbiol Mol Biol Rev (1999) 5.32
The elderly at home: health and social status. Health Trends (1984) 5.23
Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol Cell (1999) 5.09
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature (1990) 4.70
Antibody response in individuals infected with avian influenza A (H5N1) viruses and detection of anti-H5 antibody among household and social contacts. J Infect Dis (1999) 4.67
Recognition of a DNA operator by the repressor of phage 434: a view at high resolution. Science (1988) 4.60
Structure and mechanism of DNA topoisomerase II. Nature (1996) 4.56
Retrovirus envelope domain at 1.7 angstrom resolution. Nat Struct Biol (1996) 4.49
Structure of the reovirus core at 3.6 A resolution. Nature (2000) 4.28
Nonmuscle contractile proteins: the role of actin and myosin in cell motility and shape determination. Annu Rev Biochem (1977) 4.25
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell (2000) 4.21
Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature (1995) 4.08
DNA arrangement in isometric phage heads. Nature (1977) 3.98
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. Isolation and characterization of myosin from amoebae of Dictyostelium discoideum. J Mol Biol (1974) 3.91
Structure of growing microtubule ends: two-dimensional sheets close into tubes at variable rates. J Cell Biol (1995) 3.83
Structural changes and functional control of the tick-borne encephalitis virus glycoprotein E by the heterodimeric association with protein prM. Virology (1994) 3.82
Proteolytic activation of tick-borne encephalitis virus by furin. J Virol (1997) 3.78
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc Natl Acad Sci U S A (1999) 3.77
Epidemiology of the Hong Kong-68 variant of influenza A2 in Britain. Br Med J (1971) 3.74
Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nat Struct Biol (1999) 3.72
Residential care for elderly people: a decade of change. BMJ (1993) 3.71
Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature (1998) 3.71
The prevalence of dementia in Europe: a collaborative study of 1980-1990 findings. Eurodem Prevalence Research Group. Int J Epidemiol (1991) 3.70
Diffraction methods for biological macromolecules. Oscillation method with large unit cells. Methods Enzymol (1985) 3.68
Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH. J Virol (1995) 3.67
Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong. J Infect Dis (2000) 3.63
Mutational evidence for an internal fusion peptide in flavivirus envelope protein E. J Virol (2001) 3.58
Forest plots: trying to see the wood and the trees. BMJ (2001) 3.56
Protein organization in clathrin trimers. Cell (1981) 3.55
Grey literature in meta-analyses of randomized trials of health care interventions. Cochrane Database Syst Rev (2007) 3.51
Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16. Mol Cell (2000) 3.44
Development of cell surface polarity in the epithelial Madin-Darby canine kidney (MDCK) cell line. EMBO J (1984) 3.43
Attitudes to viability of preterm infants and their effect on figures for perinatal mortality. BMJ (1990) 3.43
Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment. Nature (1994) 3.35
Structure of the NF-kappa B p50 homodimer bound to DNA. Nature (1995) 3.33
Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer. Genes Dev (1994) 3.30
Difference imaging of adenovirus: bridging the resolution gap between X-ray crystallography and electron microscopy. EMBO J (1993) 3.27
Structural basis for membrane fusion by enveloped viruses. Mol Membr Biol (1999) 3.26
GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system. EMBO J (1999) 3.14
Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck. Nature (1993) 3.14
Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin. Proc Natl Acad Sci U S A (2000) 3.09
Structure of the repressor-operator complex of bacteriophage 434. Nature (1987) 3.00
Synthesis and secretion of recombinant tick-borne encephalitis virus protein E in soluble and particulate form. J Virol (1995) 2.97
Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA. Nature (1990) 2.97
The structure of simian virus 40 refined at 3.1 A resolution. Structure (1996) 2.96
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1995) 2.95
Cardiac catheterisation by the Judkins technique as an outpatient procedure. BMJ (1989) 2.92
Handsearching versus electronic searching to identify reports of randomized trials. Cochrane Database Syst Rev (2007) 2.91
Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials. Lancet (2008) 2.91
Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast. J Natl Cancer Inst Monogr (2010) 2.91
Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein E. J Virol (1999) 2.87
Tomato bushy stunt virus at 2.9 A resolution. Nature (1978) 2.87
Assessment of separate contributions to perinatal mortality of infertility history and treatment: a case-control analysis. Lancet (1999) 2.82
An enzymatic assay reveals that proteins destined for the apical or basolateral domains of an epithelial cell line share the same late Golgi compartments. EMBO J (1985) 2.78
Structure and assembly of turnip crinkle virus. II. Mechanism of reassembly in vitro. J Mol Biol (1986) 2.77
Recombinant subviral particles from tick-borne encephalitis virus are fusogenic and provide a model system for studying flavivirus envelope glycoprotein functions. J Virol (1996) 2.75
Intracellular sorting and basolateral appearance of the G protein of vesicular stomatitis virus in Madin-Darby canine kidney cells. J Cell Biol (1985) 2.75
Sequencing the termini of capped viral RNA by 5'-3' ligation and PCR. Biotechniques (1991) 2.64
Is there a single pathway for the folding of a polypeptide chain? Proc Natl Acad Sci U S A (1985) 2.62
Crystal structure of the repetitive segments of spectrin. Science (1993) 2.61
The dynamic nature of the Golgi complex. J Cell Biol (1989) 2.61
Time to publication for results of clinical trials. Cochrane Database Syst Rev (2007) 2.59
Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model. J Virol (1989) 2.59
On the fitting of model electron densities into EM reconstructions: a reciprocal-space formulation. Acta Crystallogr D Biol Crystallogr (2002) 2.53
Transferrin receptor polarity and recycling accuracy in "tight" and "leaky" strains of Madin-Darby canine kidney cells. J Cell Biol (1986) 2.52
The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis. EMBO J (2000) 2.50
Combating tuberculosis--lessons learnt from a rural community project in the Klein Drakenstein area of the Western Cape. S Afr Med J (1997) 2.50
Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments. Structure (1996) 2.49
Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro. Nature (1987) 2.49
Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment. J Cell Biol (1992) 2.45
Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion. EMBO J (2001) 2.43
Sequence of the structural proteins of tick-borne encephalitis virus (western subtype) and comparative analysis with other flaviviruses. Virology (1988) 2.43
Image reconstruction reveals the complex molecular organization of adenovirus. Cell (1991) 2.42
Prevalence of faecal incontinence in adults aged 40 years or more living in the community. Gut (2002) 2.41
The effect of membrane fixed charges on diffusion potentials and streaming potentials. J Physiol (1966) 2.38