Published in PLoS One on March 20, 2014
G-quadruplexes and their regulatory roles in biology. Nucleic Acids Res (2015) 1.43
Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun (2015) 1.03
Histone H3.3 is required to maintain replication fork progression after UV damage. Curr Biol (2014) 0.89
Stalled replication forks within heterochromatin require ATRX for protection. Cell Death Dis (2016) 0.79
The Mendelian disorders of the epigenetic machinery. Genome Res (2015) 0.79
HTML5 PivotViewer: high-throughput visualization and querying of image data on the web. Bioinformatics (2014) 0.75
The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype. Genes (Basel) (2016) 0.75
RNase P protein subunit Rpp29 represses histone H3.3 nucleosome deposition. Mol Biol Cell (2016) 0.75
ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment. Epigenetics (2016) 0.75
The Role of ATRX in Glioma Biology. Front Oncol (2017) 0.75
Telomeres shorten during ageing of human fibroblasts. Nature (1990) 23.97
A guided tour into subcellular colocalization analysis in light microscopy. J Microsc (2006) 16.73
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature (2012) 10.99
DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science (2011) 10.26
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79
Altered telomeres in tumors with ATRX and DAXX mutations. Science (2011) 4.60
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell (2010) 4.34
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet (2000) 4.30
Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet (2010) 4.26
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev (2010) 4.00
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell (2011) 3.70
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res (2010) 3.46
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell (2006) 3.45
Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J Biol Chem (1998) 3.40
Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication. Nat Cell Biol (2006) 3.22
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination. EMBO J (2009) 2.99
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. Mol Cell (2005) 2.89
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet (2012) 2.63
Chk1 regulates the density of active replication origins during the vertebrate S phase. EMBO J (2007) 2.44
Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes. Proc Natl Acad Sci U S A (1999) 2.24
Epigenetic instability due to defective replication of structured DNA. Mol Cell (2010) 1.86
Loss of ATRX leads to chromosome cohesion and congression defects. J Cell Biol (2008) 1.79
ATR activation and replication fork restart are defective in FANCM-deficient cells. EMBO J (2010) 1.75
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest (2005) 1.74
Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks. J Biol Chem (2004) 1.66
Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues. PLoS Genet (2006) 1.64
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. Dev Biol (2004) 1.60
Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres. J Biol Chem (2007) 1.55
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res (2011) 1.45
Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex. Mol Cell Biol (2005) 1.44
The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses. Cell Cycle (2007) 1.34
A modified neutral comet assay: elimination of lysis at high temperature and validation of the assay with anti-single-stranded DNA antibody. Mutat Res (2002) 1.30
The chromatin remodeller ATRX: a repeat offender in human disease. Trends Biochem Sci (2013) 1.21
Analysis of the DNA unwinding activity of RecQ family helicases. Methods Enzymol (2006) 1.18
Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA. Nucleic Acids Res (2005) 0.99
Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress. J Biol Chem (2013) 0.98
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest (2013) 0.98
Functional significance of mutations in the Snf2 domain of ATRX. Hum Mol Genet (2011) 0.96
Compromised genomic integrity impedes muscle growth after Atrx inactivation. J Clin Invest (2012) 0.92
Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet (2011) 0.92
Syndromal mental retardation due to mutations in a regulator of gene expression. Hum Mol Genet (1995) 0.89