Published in J Biol Chem on June 04, 2004
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res (2006) 4.49
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination. EMBO J (2009) 2.99
Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses. J Cell Physiol (2006) 2.83
The annealing helicase HARP protects stalled replication forks. Genes Dev (2009) 2.19
Replication protein A: directing traffic at the intersection of replication and repair. Front Biosci (Landmark Ed) (2010) 1.77
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc Natl Acad Sci U S A (2005) 1.67
Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet (2011) 1.66
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
Human cytomegalovirus disrupts both ataxia telangiectasia mutated protein (ATM)- and ATM-Rad3-related kinase-mediated DNA damage responses during lytic infection. J Virol (2006) 1.61
Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells. Oncogene (2005) 1.59
ATRIP associates with replication protein A-coated ssDNA through multiple interactions. Proc Natl Acad Sci U S A (2006) 1.55
Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress. Nucleic Acids Res (2012) 1.47
Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J (2012) 1.47
Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection. J Cell Sci (2006) 1.43
Nibrin functions in Ig class-switch recombination. Proc Natl Acad Sci U S A (2005) 1.41
The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A. Mol Cell Biol (2007) 1.38
Affinity purification of an archaeal DNA replication protein network. MBio (2010) 1.35
A role for the MRN complex in ATR activation via TOPBP1 recruitment. Mol Cell (2013) 1.31
Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage. Biochem J (2005) 1.28
Exploiting replicative stress to treat cancer. Nat Rev Drug Discov (2015) 1.27
The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress. EMBO J (2009) 1.26
Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection. EMBO J (2009) 1.24
NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse. J Cell Sci (2007) 1.14
MRE11 complex links RECQ5 helicase to sites of DNA damage. Nucleic Acids Res (2009) 1.11
Distinct roles of the ATR kinase and the Mre11-Rad50-Nbs1 complex in the maintenance of chromosomal stability in Arabidopsis. Plant Cell (2010) 1.10
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response. Cell Res (2014) 1.10
Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. Nucleic Acids Res (2004) 1.07
Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1. Biochemistry (2009) 1.07
Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN. Genes Dev (2009) 1.05
EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair. PLoS Genet (2015) 1.00
ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control. J Biol Chem (2011) 0.98
DNA ends alter the molecular composition and localization of Ku multicomponent complexes. Mol Cell Proteomics (2012) 0.96
Roles of human AND-1 in chromosome transactions in S phase. J Biol Chem (2009) 0.95
The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. Mol Biol Cell (2013) 0.94
Regression supports two mechanisms of fork processing in phage T4. Proc Natl Acad Sci U S A (2008) 0.92
ATRX dysfunction induces replication defects in primary mouse cells. PLoS One (2014) 0.92
Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC Mol Biol (2013) 0.91
Biochemistry of eukaryotic homologous recombination. Top Curr Genet (2007) 0.91
Two roles for Rad50 in telomere maintenance. EMBO J (2006) 0.91
Regulatory functions of the N-terminal domain of the 70-kDa subunit of replication protein A (RPA). J Biol Chem (2008) 0.89
Human T-lymphotropic type 1 virus p30 inhibits homologous recombination and favors unfaithful DNA repair. Blood (2011) 0.88
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA. Biol Open (2012) 0.88
Molecular mechanisms of DNA replication checkpoint activation. Genes (Basel) (2014) 0.80
Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion. Proc Natl Acad Sci U S A (2016) 0.80
The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability. Hum Mol Genet (2013) 0.80
ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Res (2015) 0.80
Theoretical prediction of the binding free energy for mutants of replication protein A. J Mol Model (2011) 0.80
RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells. Nucleic Acids Res (2015) 0.79
RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling. Nucleic Acids Res (2015) 0.78
Replicating damaged DNA in eukaryotes. Cold Spring Harb Perspect Biol (2013) 0.78
Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. PLoS One (2015) 0.76
PrimPol-Prime Time to Reprime. Genes (Basel) (2017) 0.75
Replication-mediated disassociation of replication protein A-XPA complex upon DNA damage: implications for RPA handing off. Cell Biol Int (2012) 0.75
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. PLoS Negl Trop Dis (2016) 0.75
The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype. Genes (Basel) (2016) 0.75
Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS One (2017) 0.75
Accurate prediction of the binding free energy and analysis of the mechanism of the interaction of replication protein A (RPA) with ssDNA. J Mol Model (2011) 0.75
Meiotic localization of Mre11 and Rad50 in wild type, spo11-1, and MRN complex mutants of Coprinus cinereus. Chromosoma (2009) 0.75
ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining. Cell Cycle (2010) 2.32
External validation of a clinical prediction rule to predict full recovery and ongoing moderate/severe disability following acute whiplash injury. J Orthop Sports Phys Ther (2015) 2.00
Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing. Am J Pathol (2009) 1.63
RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions. Biochemistry (2003) 1.63
Surfactant protein-d enhances phagocytosis and pulmonary clearance of respiratory syncytial virus. Am J Respir Cell Mol Biol (2004) 1.47
Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection. Am J Physiol Lung Cell Mol Physiol (2002) 1.29
DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage. Biochemistry (2005) 1.16
P-glycoprotein (MDR1) expression in leukemic cells is regulated at two distinct steps, mRNA stabilization and translational initiation. J Biol Chem (2003) 1.14
NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse. J Cell Sci (2007) 1.14
NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: a HuGE review. Genet Med (2002) 1.07
Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood (2008) 1.05
Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods. Bioorg Med Chem (2011) 1.01
DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci. J Biol Chem (2005) 1.01
The BLM helicase is necessary for normal DNA double-strand break repair. Cancer Res (2002) 0.99
A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A. Nucleic Acids Res (2012) 0.94
Helicobacter hepaticus cytolethal distending toxin causes cell death in intestinal epithelial cells via mitochondrial apoptotic pathway. Helicobacter (2010) 0.93
Rehabilitative ultrasound imaging of the posterior paraspinal muscles. J Orthop Sports Phys Ther (2007) 0.93
Orthogeriatric care in patients with fractures of the proximal femur. Clin Orthop Relat Res (2004) 0.90
Optimized manual and automated recovery of amplifiable DNA from tissues preserved in buffered formalin and alcohol-based fixative. Forensic Sci Int Genet (2009) 0.89
Neurocognitive and somatic components of temperature increases during g-tummo meditation: legend and reality. PLoS One (2013) 0.88
Deficient DNA damage signaling leads to chemoresistance to cisplatin in oral cancer. Mol Cancer Ther (2012) 0.88
Replication protein A is required for etoposide-induced assembly of MRE11/RAD50/NBS1 complex repair foci. Cell Cycle (2007) 0.88
Cell cycle-and proteasome-dependent formation of etoposide-induced replication protein A (RPA) or Mre11/Rad50/Nbs1 (MRN) complex repair foci. Cell Cycle (2007) 0.86
ATM mediates repression of DNA end-degradation in an ATP-dependent manner. DNA Repair (Amst) (2008) 0.85
UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK. DNA Repair (Amst) (2006) 0.85
Hip fracture in Northern Ireland, 1985-2010. Are age-specific fracture rates still rising? Ulster Med J (2012) 0.84
Pain-induced changes in the activity of the cervical extensor muscles evaluated by muscle functional magnetic resonance imaging. Clin J Pain (2011) 0.83
The geography of fatty infiltrates within the cervical multifidus and semispinalis cervicis in individuals with chronic whiplash-associated disorders. J Orthop Sports Phys Ther (2015) 0.82
BRCA1 requirement for the fidelity of plasmid DNA double-strand break repair in cultured breast epithelial cells. Environ Mol Mutagen (2011) 0.82
Implantation of oxygen enhanced, three-dimensional microporous L-PLA polymers: a reproducible porcine model of chronic total coronary occlusion. Catheter Cardiovasc Interv (2006) 0.81
A comparative evaluation of arterial blood flow and the healing response after femoral artery closure using angio-seal STS Plus and StarClose in a porcine model. J Interv Cardiol (2008) 0.80
Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling. Exp Cell Res (2011) 0.80
Transforming growth factor-β activates c-Myc to promote palatal growth. J Cell Biochem (2012) 0.79
Interleukin-1 alpha genotype and outcome of unrelated donor haematopoietic stem cell transplantation for chronic myeloid leukaemia. Br J Haematol (2007) 0.79
Fluoroscopically guided cervical prolotherapy for instability with blinded pre and post radiographic reading. Pain Physician (2005) 0.79
Insights into UV-induced apoptosis: ultrastructure, trichrome stain and spectral imaging. Micron (2002) 0.78
In vivo evaluation of a biolimus eluting nickel titanium self expanding stent with overlapping balloon expandable drug eluting and bare metal stents in a porcine coronary model. EuroIntervention (2009) 0.78
Total cervical translation as a function of impact vector as measured by flexion-extension radiography. Pain Physician (2007) 0.77
Effects of formulation on the bioavailability of lutein and zeaxanthin: a randomized, double-blind, cross-over, comparative, single-dose study in healthy subjects. Eur J Nutr (2012) 0.77
Development of a total atherosclerotic occlusion with cell-mediated calcium deposits in a rabbit femoral artery using tissue-engineering scaffolds. J Tissue Eng Regen Med (2011) 0.76
The Traumatic Injuries Distress Scale: A New Tool That Quantifies Distress and Has Predictive Validity With Patient-Reported Outcomes. J Orthop Sports Phys Ther (2016) 0.75
Absence of the inferior portion of the trapezius muscle in three family members. Man Ther (2011) 0.75
Cluster Analysis of an International Pressure Pain Threshold Database Identifies 4 Meaningful Subgroups of Adults With Mechanical Neck Pain. Clin J Pain (2017) 0.75
Research priorities in the field of post-traumatic pain and disability: Results of a transdisciplinary consensus-generating workshop. Pain Res Manag (2015) 0.75
Zinc toxicity in two dogs associated with the ingestion of identification tags. Vet Rec (2011) 0.75
Accelerated exposure of phosphatidylserine on lymphocyte populations from patients with systemic lupus erythematosus or rheumatoid arthritis. Thromb Haemost (2005) 0.75
Variations in compaction behaviour for tablets of different size and shape, revealed by small-angle X-ray scattering. J Pharm Sci (2010) 0.75
Management with Two-Way Stretch. Ment Health (Lond) (1971) 0.75
Palliative care experiences in regional NSW. Aust Nurs Midwifery J (2015) 0.75
Evaluating serratus anterior muscle function in neck pain using muscle functional magnetic resonance imaging. J Manipulative Physiol Ther (2012) 0.75
Acute aerobic exercise modulates feature selectivity in human visual cortex. J Vis (2015) 0.75
Ankylosing spondylitis in a patient referred to physical therapy with low back pain. Physiother Theory Pract (2011) 0.75
The case of the missing lower trapezius muscle. J Orthop Sports Phys Ther (2011) 0.75