Published in Transl Psychiatry on March 25, 2014
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Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies. PLoS Genet (2015) 1.20
DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites. J Biol Chem (2015) 0.96
Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Mol Psychiatry (2014) 0.93
GIT1 and βPIX are essential for GABA(A) receptor synaptic stability and inhibitory neurotransmission. Cell Rep (2014) 0.91
BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1. J Neurosci (2015) 0.91
Non-signalling energy use in the brain. J Physiol (2015) 0.89
MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus. J Neurosci (2014) 0.88
Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling. J Neurosci (2015) 0.86
Diametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunology. Evol Med Public Health (2015) 0.85
Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models. Dev Neurobiol (2016) 0.80
Full-field electroretinogram in autism spectrum disorder. Doc Ophthalmol (2016) 0.79
Genetic and morphological features of human iPSC-derived neurons with chromosome 15q11.2 (BP1-BP2) deletions. Mol Neuropsychiatry (2015) 0.79
The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Mol Psychiatry (2016) 0.79
The effects of aging on the BTBR mouse model of autism spectrum disorder. Front Aging Neurosci (2014) 0.78
Neuronal activity mediated regulation of glutamate transporter GLT-1 surface diffusion in rat astrocytes in dissociated and slice cultures. Glia (2016) 0.78
A unique binding mode of the eukaryotic translation initiation factor 4E for guiding the design of novel peptide inhibitors. Protein Sci (2015) 0.77
Parental origin impairment of synaptic functions and behaviors in cytoplasmic FMRP interacting protein 1 (Cyfip1) deficient mice. Brain Res (2015) 0.76
A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons. Front Cell Neurosci (2016) 0.76
The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse. J Neurosci (2016) 0.76
Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss. Brain (2016) 0.76
Cyfip1 Regulates Presynaptic Activity during Development. J Neurosci (2016) 0.75
The neurobiology of the Prader-Willi phenotype of fragile X syndrome. Intractable Rare Dis Res (2016) 0.75
15q11.2 CNV affects cognitive, structural and functional correlates of dyslexia and dyscalculia. Transl Psychiatry (2017) 0.75
Substrate-Mediated Laser Ablation under Ambient Conditions for Spatially-Resolved Tissue Proteomics. Sci Rep (2015) 0.75
Hypomethylation and Genetic Instability in Monosomy Blastocysts May Contribute to Decreased Implantation Potential. PLoS One (2016) 0.75
Genome-wide copy number variation analysis in a Chinese autism spectrum disorder cohort. Sci Rep (2017) 0.75
Super resolution microscopy is poised to reveal new insights into the formation and maturation of dendritic spines. F1000Res (2016) 0.75
Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus. Proc Natl Acad Sci U S A (2017) 0.75
Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks. PLoS One (2016) 0.75
New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes. Dis Model Mech (2017) 0.75
Miro1-dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity. EMBO Rep (2016) 0.75
Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder? Int J Mol Sci (2017) 0.75
Low-Density Neuronal Cultures from Human Induced Pluripotent Stem Cells. Mol Neuropsychiatry (2017) 0.75
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Structural basis of long-term potentiation in single dendritic spines. Nature (2004) 11.50
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Dendritic spine pathology in neuropsychiatric disorders. Nat Neurosci (2011) 4.80
Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat Neurosci (2004) 4.57
Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo. Neuron (2003) 4.47
Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice. Neuron (2002) 4.18
Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy. Nat Rev Neurosci (2008) 3.83
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The interaction between Stargazin and PSD-95 regulates AMPA receptor surface trafficking. Neuron (2007) 3.25
Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu Rev Cell Dev Biol (2002) 3.15
The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell (2008) 3.10
New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales. Neuroscience (2005) 3.06
CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein. Neuron (2003) 2.92
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat Neurosci (2010) 2.90
Unraveling mechanisms of homeostatic synaptic plasticity. Neuron (2010) 2.85
Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet (2012) 2.65
Regulation of AMPA receptor trafficking and synaptic plasticity. Curr Opin Neurobiol (2012) 2.61
Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways. Hum Mol Genet (2007) 2.55
Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron (2013) 2.45
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines. Nature (1996) 2.37
Probing cellular events, one quantum dot at a time. Nat Methods (2010) 2.27
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci (2004) 2.26
Structure and control of the actin regulatory WAVE complex. Nature (2010) 2.25
Activity-dependent neuronal signalling and autism spectrum disorder. Nature (2013) 2.23
Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol (2009) 2.21
Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice. Neuron (2004) 2.14
How is actin polymerization nucleated in vivo? Trends Cell Biol (2001) 2.09
Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation. Cell (2012) 2.02
New concepts in synaptic biology derived from single-molecule imaging. Neuron (2008) 1.99
WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J (2003) 1.98
Contribution of cytoskeleton to the internalization of AMPA receptors. Proc Natl Acad Sci U S A (2001) 1.83
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity. Nat Neurosci (2010) 1.82
Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation. Mol Psychiatry (2010) 1.80
SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism. Mol Psychiatry (2011) 1.79
CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation. Mol Cell Biol (2005) 1.64
PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking. EMBO J (2005) 1.62
Synapse pathology in psychiatric and neurologic disease. Curr Neurol Neurosci Rep (2010) 1.61
Nine patients with a microdeletion 15q11.2 between breakpoints 1 and 2 of the Prader-Willi critical region, possibly associated with behavioural disturbances. Eur J Med Genet (2009) 1.60
FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts. Hum Mol Genet (2005) 1.60
The dendritic tree and brain disorders. Mol Cell Neurosci (2012) 1.55
Actin dynamics: assembly and disassembly of actin networks. Curr Biol (2001) 1.44
Confirmed rare copy number variants implicate novel genes in schizophrenia. Biochem Soc Trans (2010) 1.42
Independent expression of synaptic and morphological plasticity associated with long-term depression. J Neurosci (2007) 1.42
Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching. Development (2006) 1.38
Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader-Willi syndrome. Pediatrics (2006) 1.36
Regulation of AMPA receptor surface diffusion by PSD-95 slots. Curr Opin Neurobiol (2011) 1.36
PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity. EMBO J (2011) 1.22
Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities. J Neurosci (2013) 1.19
NMDA receptors regulate GABAA receptor lateral mobility and clustering at inhibitory synapses through serine 327 on the γ2 subunit. Proc Natl Acad Sci U S A (2010) 1.18
Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. PLoS Biol (2010) 1.17
Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition. Proc Natl Acad Sci U S A (2009) 1.13
Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol (2010) 1.11
A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder. Am J Med Genet B Neuropsychiatr Genet (2010) 1.06
Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum Disorders. J Neurodev Disord (2011) 1.04
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice. PLoS One (2012) 1.01
The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity. Neuron (2013) 0.97
Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly. PLoS Genet (2013) 0.93
Valosin-containing protein and neurofibromin interact to regulate dendritic spine density. J Clin Invest (2011) 0.91
Activity-regulated, cytoskeleton-associated protein (Arc) is essential for visceral endoderm organization during early embryogenesis. Mech Dev (2000) 0.82
Clinical and genetic study of a family with a paternally inherited 15q11-q13 duplication. Am J Med Genet A (2013) 0.81
Methods to measure actin treadmilling rate in dendritic spines. Methods Enzymol (2012) 0.80
NESH regulates dendritic spine morphology and synapse formation. PLoS One (2012) 0.80