Augusto A Litonjua

Author PubWeight™ 153.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 2009 5.20
2 Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med 2009 4.64
3 MMP12, lung function, and COPD in high-risk populations. N Engl J Med 2009 3.96
4 Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 2007 3.89
5 Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med 2011 3.80
6 Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol 2010 3.54
7 Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet 2010 3.44
8 Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr 2007 3.40
9 Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality. Crit Care Med 2012 2.97
10 Statin use reduces decline in lung function: VA Normative Aging Study. Am J Respir Crit Care Med 2007 2.65
11 The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Am J Hum Genet 2005 2.46
12 Uric acid and the development of hypertension: the normative aging study. Hypertension 2006 2.45
13 Association of low serum 25-hydroxyvitamin D levels and sepsis in the critically ill. Crit Care Med 2014 2.38
14 Association between prehospital vitamin D status and hospital-acquired bloodstream infections. Am J Clin Nutr 2013 2.21
15 The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet 2004 2.19
16 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet 2011 2.10
17 Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol 2005 2.08
18 A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet 2011 1.98
19 Genetic determinants of emphysema distribution in the national emphysema treatment trial. Am J Respir Crit Care Med 2007 1.94
20 Vitamin D deficiency in pregnancy and gestational diabetes mellitus. Am J Obstet Gynecol 2012 1.93
21 Association of low serum 25-hydroxyvitamin D levels and acute kidney injury in the critically ill. Crit Care Med 2012 1.78
22 Vitamin D deficiency, smoking, and lung function in the Normative Aging Study. Am J Respir Crit Care Med 2012 1.75
23 Maternal diet vs lack of exposure to sunlight as the cause of the epidemic of asthma, allergies and other autoimmune diseases. Thorax 2007 1.67
24 Long-term effects of traffic particles on lung function decline in the elderly. Am J Respir Crit Care Med 2014 1.66
25 Sensitization to mouse allergen and asthma and asthma morbidity among women in Boston. J Allergy Clin Immunol 2007 1.60
26 Air pollution and ST-segment depression in elderly subjects. Environ Health Perspect 2005 1.56
27 African ancestry and lung function in Puerto Rican children. J Allergy Clin Immunol 2012 1.54
28 Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood. J Allergy Clin Immunol 2007 1.53
29 Vitamin D insufficiency and severe asthma exacerbations in Puerto Rican children. Am J Respir Crit Care Med 2012 1.46
30 Statin use in asthmatics on inhaled corticosteroids is associated with decreased risk of emergency department visits. Curr Med Res Opin 2013 1.44
31 FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma. J Allergy Clin Immunol 2007 1.40
32 Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program. J Allergy Clin Immunol 2008 1.36
33 Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study. Cancer Causes Control 2010 1.30
34 Predictors of cord blood IgE levels in children at risk for asthma and atopy. J Allergy Clin Immunol 2006 1.27
35 Exposure to cat allergen, maternal history of asthma, and wheezing in first 5 years of life. Lancet 2002 1.27
36 Day care attendance in early life, maternal history of asthma, and asthma at the age of 6 years. Am J Respir Crit Care Med 2002 1.26
37 Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest 2007 1.25
38 Plasma 25-hydroxyvitamin D during pregnancy and small-for-gestational age in black and white infants. Ann Epidemiol 2012 1.24
39 Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways. Hum Mol Genet 2005 1.23
40 Low-normal gestational age as a predictor of asthma at 6 years of age. Pediatrics 2004 1.18
41 Higher adiposity in infancy associated with recurrent wheeze in a prospective cohort of children. J Allergy Clin Immunol 2008 1.18
42 Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr 2005 1.17
43 The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility. Am J Respir Cell Mol Biol 2011 1.17
44 A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2005 1.14
45 Endotoxin exposure and eczema in the first year of life. Pediatrics 2004 1.13
46 Vitamin D deficiency is associated with decreased lung function in Chinese adults with asthma. Respiration 2010 1.13
47 Evidence for a U-shaped relationship between prehospital vitamin D status and mortality: a cohort study. J Clin Endocrinol Metab 2014 1.12
48 Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One 2011 1.11
49 Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: prospective results from a folate-replete population. Epigenetics 2012 1.10
50 Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet 2012 1.09
51 Mode of delivery and cord blood cytokines: a birth cohort study. Clin Mol Allergy 2006 1.07
52 Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility. Physiol Genomics 2006 1.05
53 Sensitization to aeroallergens and airway hyperresponsiveness at 7 years of age. Chest 2006 1.05
54 Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers. BMC Med Genet 2011 1.04
55 Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2010 1.04
56 Prevalence and titer of IgE antibodies to mouse allergens. J Allergy Clin Immunol 2007 1.03
57 Pre-hospital vitamin D concentration, mortality, and bloodstream infection in a hospitalized patient population. Am J Med 2013 1.01
58 Lack of association between antibiotic use in the first year of life and asthma, allergic rhinitis, or eczema at age 5 years. Am J Respir Crit Care Med 2002 1.00
59 Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics 2009 0.99
60 Associations of LINE-1 DNA Methylation with Preterm Birth in a Prospective Cohort Study. J Dev Orig Health Dis 2012 0.99
61 Ambient air pollution and oxygen saturation. Am J Respir Crit Care Med 2004 0.99
62 Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol 2009 0.98
63 Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma. Pharmacogenet Genomics 2008 0.98
64 Diversity of the gut microbiota and eczema in early life. Clin Mol Allergy 2008 0.97
65 The in utero effects of maternal vitamin D deficiency: how it results in asthma and other chronic diseases. Am J Respir Crit Care Med 2011 0.95
66 Corticosteroid use and bone mineral accretion in children with asthma: effect modification by vitamin D. J Allergy Clin Immunol 2012 0.95
67 Gene promoter methylation is associated with lung function in the elderly: the Normative Aging Study. Epigenetics 2012 0.95
68 Bottle feeding in the bed or crib before sleep time and wheezing in early childhood. Pediatrics 2002 0.94
69 Diagnostic accuracy of the bronchodilator response in children. J Allergy Clin Immunol 2013 0.93
70 Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma. Pharmacogenet Genomics 2008 0.93
71 Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD 2011 0.93
72 Association of variants in innate immune genes with asthma and eczema. Pediatr Allergy Immunol 2011 0.93
73 Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Hum Genet 2013 0.92
74 Predicting response to short-acting bronchodilator medication using Bayesian networks. Pharmacogenomics 2009 0.92
75 Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax 2011 0.91
76 Genetic and histologic evidence for autophagy in asthma pathogenesis. J Allergy Clin Immunol 2011 0.91
77 Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One 2013 0.91
78 Cord blood cytokines and acute lower respiratory illnesses in the first year of life. Pediatrics 2006 0.90
79 Day care attendance, respiratory tract illnesses, wheezing, asthma, and total serum IgE level in early childhood. Arch Pediatr Adolesc Med 2002 0.90
80 Maternal dietary pattern during pregnancy is not associated with recurrent wheeze in children. J Allergy Clin Immunol 2010 0.90
81 Paternal history of asthma and airway responsiveness in children with asthma. Am J Respir Crit Care Med 2005 0.89
82 Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men. Atherosclerosis 2009 0.89
83 Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes. BMC Med Genet 2011 0.89
84 Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells. Genomics 2013 0.89
85 Genetic linkage and association analysis of COPD-related traits on chromosome 8p. COPD 2006 0.89
86 Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med 2010 0.89
87 Respiratory illnesses in early life and asthma and atopy in childhood. J Allergy Clin Immunol 2006 0.89
88 Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med 2010 0.88
89 Genome-wide association analysis of circulating vitamin D levels in children with asthma. Hum Genet 2012 0.88
90 SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development. Am J Respir Crit Care Med 2011 0.88
91 Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations. Am J Respir Crit Care Med 2010 0.87
92 Association between 24-hour urinary cadmium and pulmonary function among community-exposed men: the VA Normative Aging Study. Environ Health Perspect 2008 0.86
93 Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations. J Allergy Clin Immunol 2011 0.86
94 Prenatal, perinatal, and heritable influences on cord blood immune responses. Ann Allergy Asthma Immunol 2006 0.85
95 Folliculin mutations are not associated with severe COPD. BMC Med Genet 2008 0.85
96 Forced expiratory volume in 1 second and cognitive aging in men. J Am Geriatr Soc 2011 0.85
97 Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter. Environ Health Perspect 2009 0.85
98 Alu and LINE-1 methylation and lung function in the normative ageing study. BMJ Open 2012 0.85
99 Analysis of exonic elastin variants in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2008 0.83
100 Very important pharmacogene summary for VDR. Pharmacogenet Genomics 2012 0.82
101 Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study. BMC Med Genet 2011 0.82
102 Allergen sensitization is associated with increased DNA methylation in older men. Int Arch Allergy Immunol 2012 0.81
103 Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1. BMC Med Genet 2011 0.81
104 Early pregnancy vitamin D status and risk of preeclampsia. J Clin Invest 2016 0.80
105 Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol 2003 0.80
106 Folate network genetic variation predicts cardiovascular disease risk in non-Hispanic white males. J Nutr 2012 0.80
107 Relevance and implication of genetic determinants to asthma pathophysiology. Curr Opin Allergy Clin Immunol 2011 0.78
108 Genome-wide association studies of family data in pharmacogenetics: a case study. Curr Pharm Des 2009 0.77
109 Vitamin D, the gut microbiome, and the hygiene hypothesis. How does asthma begin? Am J Respir Crit Care Med 2015 0.77
110 Vitamin D insufficiency. N Engl J Med 2011 0.76
111 Vitamin D and corticosteroids in asthma: synergy, interaction and potential therapeutic effects. Expert Rev Respir Med 2013 0.76
112 INSIG2 is Associated with Lower Gain in Weight-for-Length Between Birth and Age 6 Months. Clin Med Pediatr 2009 0.75
113 Exposure to traffic and early life respiratory infection: A cohort study. Pediatr Pulmonol 2014 0.75