Reporting discrepancies between the ClinicalTrials.gov results database and peer-reviewed publications.

How to get all trials reported: audit, better data, and individual accountability. PLoS Med (2015) 1.26

Terminated Trials in the ClinicalTrials.gov Results Database: Evaluation of Availability of Primary Outcome Data and Reasons for Termination. PLoS One (2015) 1.02

Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement. J Am Coll Cardiol (2014) 1.02

Comparison of registered and published outcomes in randomized controlled trials: a systematic review. BMC Med (2015) 1.01

Making research articles fit for purpose: structured reporting of key methods and findings. Trials (2015) 0.99

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure. Eur Heart J (2016) 0.91

OpenTrials: towards a collaborative open database of all available information on all clinical trials. Trials (2016) 0.90

Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytes. Clin Exp Vaccine Res (2015) 0.89

From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology. J Clin Oncol (2015) 0.89

Reporting of Adverse Events in Published and Unpublished Studies of Health Care Interventions: A Systematic Review. PLoS Med (2016) 0.88

Reporting discrepancies between the clinicaltrials.gov results database and peer-reviewed publications. Ann Intern Med (2014) 0.84

Comparison of serious adverse events posted at ClinicalTrials.gov and published in corresponding journal articles. BMC Med (2015) 0.80

Publication and non-publication of drug trial results: a 10-year cohort of trials in Norwegian general practice. BMJ Open (2016) 0.78

Guidelines for the Reporting of Treatment Trials for Alcohol Use Disorders. Alcohol Clin Exp Res (2015) 0.78

Prevention of selective outcome reporting: let us start from the beginning. Eur J Clin Pharmacol (2016) 0.77

Public availability of results of observational studies evaluating an intervention registered at ClinicalTrials.gov. BMC Med (2016) 0.77

ClinicalTrials.gov and Drugs@FDA: A Comparison of Results Reporting for New Drug Approval Trials. Ann Intern Med (2016) 0.77

The safety and efficacy of vortioxetine for acute treatment of major depressive disorder: a systematic review and meta-analysis. Syst Rev (2015) 0.76

Major discrepancies between what clinical trial registries record and paediatric randomised controlled trials publish. Trials (2016) 0.75

Clinical research data sharing: what an open science world means for researchers involved in evidence synthesis. Syst Rev (2016) 0.75

Evaluation of Adverse Events in Total Disc Replacement: A Meta-Analysis of FDA Summary of Safety and Effectiveness Data. Global Spine J (2017) 0.75

Semantic biomedical resource discovery: a Natural Language Processing framework. BMC Med Inform Decis Mak (2015) 0.75

Results in journals often fail to match those on ClinicalTrials.gov, study finds. BMJ (2014) 0.75

Reporting of statistically significant results at ClinicalTrials.gov for completed superiority randomized controlled trials. BMC Med (2016) 0.75

Outcome reporting bias in randomized-controlled trials investigating antipsychotic drugs. Transl Psychiatry (2017) 0.75

Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles. JAMA (2004) 23.87

A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J (2011) 10.70

The ClinicalTrials.gov results database--update and key issues. N Engl J Med (2011) 9.83

Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas. JAMA (2001) 8.15

Comparison of registered and published primary outcomes in randomized controlled trials. JAMA (2009) 7.89

Issues in the registration of clinical trials. JAMA (2007) 5.92

Dissemination and publication of research findings: an updated review of related biases. Health Technol Assess (2010) 5.11

Effectiveness and harms of recombinant human bone morphogenetic protein-2 in spine fusion: a systematic review and meta-analysis. Ann Intern Med (2013) 4.60

Medicine. Moving toward transparency of clinical trials. Science (2008) 4.36

Reporting of safety results in published reports of randomized controlled trials. Arch Intern Med (2009) 4.19

Reporting "basic results" in ClinicalTrials.gov. Chest (2009) 2.84

Ushering in a new era of open science through data sharing: the wall must come down. JAMA (2013) 2.14

Completeness and changes in registered data and reporting bias of randomized controlled trials in ICMJE journals after trial registration policy. PLoS One (2011) 1.98

Adverse events in randomized trials: neglected, restricted, distorted, and silenced. Arch Intern Med (2009) 1.53

A model for dissemination and independent analysis of industry data. JAMA (2011) 1.35

Undisclosed changes in outcomes in randomized controlled trials: an observational study. Ann Fam Med (2009) 1.33

Haphazard reporting of deaths in clinical trials: a review of cases of ClinicalTrials.gov records and matched publications-a cross-sectional study. BMJ Open (2013) 1.12

Breast cancer screening: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med (2002) 12.65

GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol (2011) 10.02

Characteristics of clinical trials registered in ClinicalTrials.gov, 2007-2010. JAMA (2012) 6.56

Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis. BMJ (2012) 6.39

Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop. Ann Intern Med (2015) 5.12

Effectiveness and harms of recombinant human bone morphogenetic protein-2 in spine fusion: a systematic review and meta-analysis. Ann Intern Med (2013) 4.60

Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med (2008) 3.54

C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses for the U.S. Preventive Services Task Force. Ann Intern Med (2009) 3.50

Comparative efficacy and safety of long-acting oral opioids for chronic non-cancer pain: a systematic review. J Pain Symptom Manage (2003) 3.33

Routine iron supplementation and screening for iron deficiency anemia in pregnancy: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med (2015) 3.31

Screening for postmenopausal osteoporosis: a review of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med (2002) 3.06

GRADE guidelines: 7. Rating the quality of evidence--inconsistency. J Clin Epidemiol (2011) 3.02

Intensive insulin therapy in hospitalized patients: a systematic review. Ann Intern Med (2011) 2.94

Reporting "basic results" in ClinicalTrials.gov. Chest (2009) 2.84

GRADE guidelines: 8. Rating the quality of evidence--indirectness. J Clin Epidemiol (2011) 2.83

Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis. Mayo Clin Proc (2008) 2.83

AHRQ series paper 5: grading the strength of a body of evidence when comparing medical interventions--agency for healthcare research and quality and the effective health-care program. J Clin Epidemiol (2010) 2.63

Screening for hepatitis C virus infection: a review of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med (2004) 2.57

The cost-effectiveness of screening mammography beyond age 65 years: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med (2003) 2.31

Safe prevention of the primary cesarean delivery. Am J Obstet Gynecol (2014) 2.22

Hyperbaric oxygen therapy for traumatic brain injury: a systematic review of the evidence. Arch Phys Med Rehabil (2004) 2.16

Challenges in systematic reviews of diagnostic technologies. Ann Intern Med (2005) 2.05

Systematic review of the incidence and consequences of uterine rupture in women with previous caesarean section. BMJ (2004) 1.94

Incorporating considerations of resources use into grading recommendations. BMJ (2008) 1.94

Metabolic testing rates in 3 state Medicaid programs after FDA warnings and ADA/APA recommendations for second-generation antipsychotic drugs. Arch Gen Psychiatry (2010) 1.82

Challenges in systematic reviews that assess treatment harms. Ann Intern Med (2005) 1.82

Vaginal birth after cesarean: new insights. Evid Rep Technol Assess (Full Rep) (2010) 1.78

GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes. J Clin Epidemiol (2012) 1.75

AHRQ series paper 3: identifying, selecting, and refining topics for comparative effectiveness systematic reviews: AHRQ and the effective health-care program. J Clin Epidemiol (2009) 1.73

The effectiveness of primary care-based interventions to promote breastfeeding: systematic evidence review and meta-analysis for the US Preventive Services Task Force. Ann Fam Med (2004) 1.72

Cross-topic learning for work prioritization in systematic review creation and update. J Am Med Inform Assoc (2009) 1.70

Salvation by registration. N Engl J Med (2007) 1.63

Safety of vaginal birth after cesarean: a systematic review. Obstet Gynecol (2004) 1.58

Small area variation and geographic and patient-specific determinants of metabolic testing in antipsychotic users. Pharmacoepidemiol Drug Saf (2010) 1.58

Vaginal birth after cesarean: new insights on maternal and neonatal outcomes. Obstet Gynecol (2010) 1.57

Evidence on the benefits and harms of screening and treating pregnant women who are asymptomatic for bacterial vaginosis: an update review for the U.S. Preventive Services Task Force. Ann Intern Med (2008) 1.55

Screening for developmental dysplasia of the hip: a systematic literature review for the US Preventive Services Task Force. Pediatrics (2006) 1.51

A new taxonomy for stakeholder engagement in patient-centered outcomes research. J Gen Intern Med (2012) 1.47

Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review. J Pain Symptom Manage (2004) 1.41

Registration of observational studies: is it time? CMAJ (2010) 1.33

Metabolic screening in children receiving antipsychotic drug treatment. Arch Pediatr Adolesc Med (2010) 1.32

Reducing risk for mother-to-infant transmission of hepatitis C virus: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med (2012) 1.30

GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence. J Clin Epidemiol (2012) 1.30

Predicting vaginal birth after cesarean delivery: a review of prognostic factors and screening tools. Am J Obstet Gynecol (2004) 1.29

Hyperbaric oxygen for treating wounds: a systematic review of the literature. Arch Surg (2003) 1.23

Diagnosis, access and outcomes: Update of a systematic review of telemedicine services. J Telemed Telecare (2006) 1.22

Improving the follow-up of positive hemoccult screening tests: an electronic intervention. J Gen Intern Med (2011) 1.21

A systematic review of pneumatic compression for treatment of chronic venous insufficiency and venous ulcers. J Vasc Surg (2003) 1.20

Projected cost-effectiveness of statewide universal newborn hearing screening. Pediatrics (2002) 1.18

Update on Registration of Clinical Trials in ClinicalTrials.gov. Chest (2009) 1.18

Childbirth preferences after cesarean birth: a review of the evidence. Birth (2004) 1.14

Interventions to promote breast-feeding: applying the evidence in clinical practice. CMAJ (2004) 1.14

Impact of multiple cesarean deliveries on maternal morbidity: a systematic review. Am J Obstet Gynecol (2011) 1.13

Effect of mode of delivery on the incidence of urinary incontinence in primiparous women. Obstet Gynecol (2009) 1.12

A systematic review of the efficacy of telemedicine for making diagnostic and management decisions. J Telemed Telecare (2002) 1.12

Screening for hepatitis C virus infection in adults: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med (2013) 1.09

Challenges in the development and reimbursement of personalized medicine-payer and manufacturer perspectives and implications for health economics and outcomes research: a report of the ISPOR personalized medicine special interest group. Value Health (2012) 1.08

Concomitant pharmacotherapy among youths treated in routine psychiatric practice. J Child Adolesc Psychopharmacol (2005) 1.07

Clarification about ClinicalTrials.gov. IRB (2013) 1.07

Telemedicine for the medicare population: update. Evid Rep Technol Assess (Full Rep) (2006) 1.04

Comparative effectiveness research: challenges for medical journals. PLoS Med (2010) 1.03

Methodological shortcomings predicted lower harm estimates in one of two sets of studies of clinical interventions. J Clin Epidemiol (2006) 1.03

Understanding safety in prehospital emergency medical services for children. Prehosp Emerg Care (2014) 1.01

Examining the value of electronic health records on labor and delivery. Am J Obstet Gynecol (2008) 0.99

Hyperbaric oxygen therapy for stroke: a systematic review of the evidence. Clin Rehabil (2005) 0.99

Delivery after prior cesarean: maternal morbidity and mortality. Clin Perinatol (2011) 0.99

Participant-level data and the new frontier in trial transparency. N Engl J Med (2013) 0.96

Patients were more consistent in randomized trial at prioritizing childbirth preferences using graphic-numeric than verbal formats. J Clin Epidemiol (2008) 0.96

Training and career development for comparative effectiveness research workforce development: CTSA Consortium Strategic Goal Committee on comparative effectiveness research workgroup on workforce development. Clin Transl Sci (2010) 0.94

Role of practice-based research networks in comparative effectiveness research. J Comp Eff Res (2012) 0.94

Cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack. Med Decis Making (2007) 0.94

Planned elective repeat caesarean section versus planned vaginal birth for women with a previous caesarean birth. Cochrane Database Syst Rev (2013) 0.94

A Prospective Evaluation of an Automated Classification System to Support Evidence-based Medicine and Systematic Review. AMIA Annu Symp Proc (2010) 0.93

Systematic review of the literature on pain in patients with polytrauma including traumatic brain injury. Pain Med (2009) 0.93

A national strategy to develop pragmatic clinical trials infrastructure. Clin Transl Sci (2014) 0.93

Studying the potential impact of automated document classification on scheduling a systematic review update. BMC Med Inform Decis Mak (2012) 0.92

Considering usual medical care in clinical trial design. PLoS Med (2009) 0.91

Frequency and predictors for postpartum fecal incontinence. Am J Obstet Gynecol (2003) 0.91

Depression drug treatment outcomes in pregnancy and the postpartum period: a systematic review and meta-analysis. Obstet Gynecol (2014) 0.90

Trust but verify: trial registration and determining fidelity to the protocol. Ann Intern Med (2013) 0.90

Identifying research needs for improving health care. Ann Intern Med (2012) 0.88

Estimating risk of breast cancer in carriers of BRCA1 and BRCA2 mutations: a meta-analytic approach. Stat Med (2007) 0.88

Economic comparison of diagnostic approaches for evaluating osteoporosis in older women. Osteoporos Int (2005) 0.87

Screening for elevated lead levels in childhood and pregnancy: an updated summary of evidence for the US Preventive Services Task Force. Pediatrics (2006) 0.87

Patient-centered collaborative care: the impact of a new approach to postpartum rounds on residents' perception of their work environment. J Grad Med Educ (2010) 0.87

Vaginal birth after cesarean: a prenatal scoring tool. Am J Obstet Gynecol (2007) 0.86

The benefits and risks of inducing labour in patients with prior caesarean delivery: a systematic review. BJOG (2005) 0.85

US Food and Drug Administration documents can provide unpublished evidence relevant to systematic reviews. J Clin Epidemiol (2013) 0.85

Initial results of the use of prescription order change forms to achieve dose form optimization (consolidation and tablet splitting) of SSRI antidepressants in a state Medicaid program. J Manag Care Pharm (2006) 0.85

Quality of life in women with postpartum anal incontinence. Obstet Gynecol (2010) 0.84

Subjective risk vs. objective risk can lead to different post-cesarean birth decisions based on multiattribute modeling. J Clin Epidemiol (2010) 0.84

Children's safety initiative: a national assessment of pediatric educational needs among emergency medical services providers. Prehosp Emerg Care (2014) 0.84

Pediatric Airway Management and Prehospital Patient Safety: Results of a National Delphi Survey by the Children's Safety Initiative-Emergency Medical Services for Children. Pediatr Emerg Care (2016) 0.82

The evaluation of rectal bleeding in adults. A cost-effectiveness analysis comparing four diagnostic strategies. J Gen Intern Med (2005) 0.82