From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.

PubWeight™: 0.89‹?›

🔗 View Article (PMID 26304898)

Published in J Clin Oncol on August 24, 2015

Authors

Kanwal Pratap Singh Raghav1, Sminil Mahajan1, James C Yao1, Brian P Hobbs1, Donald A Berry1, Rebecca D Pentz1, Alda Tam1, Waun K Hong1, Lee M Ellis1, James Abbruzzese1, Michael J Overman2

Author Affiliations

1: Kanwal Pratap Singh Raghav, Sminil Mahajan, James C. Yao, Brian P. Hobbs, Donald A. Berry, Alda Tam, Waun K. Hong, Lee M. Ellis, and Michael J. Overman, The University of Texas MD Anderson Cancer Center, Houston, TX; Rebecca D. Pentz, Emory School of Medicine, Atlanta, GA; and James Abbruzzese, Duke Cancer Institute, Durham, NC.
2: Kanwal Pratap Singh Raghav, Sminil Mahajan, James C. Yao, Brian P. Hobbs, Donald A. Berry, Alda Tam, Waun K. Hong, Lee M. Ellis, and Michael J. Overman, The University of Texas MD Anderson Cancer Center, Houston, TX; Rebecca D. Pentz, Emory School of Medicine, Atlanta, GA; and James Abbruzzese, Duke Cancer Institute, Durham, NC. moverman@mdanderson.org.

Articles cited by this

Improving the quality of reporting of randomized controlled trials. The CONSORT statement. JAMA (1996) 36.04

Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles. JAMA (2004) 23.87

Publication bias in clinical research. Lancet (1991) 22.85

Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med (2008) 19.86

Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ (2003) 18.72

Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research. CMAJ (2004) 10.75

SPIRIT 2013 statement: defining standard protocol items for clinical trials. Ann Intern Med (2013) 8.21

The uncertainty principle and industry-sponsored research. Lancet (2000) 7.75

Proposal for standardized definitions for efficacy end points in adjuvant breast cancer trials: the STEEP system. J Clin Oncol (2007) 6.11

The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ (2010) 5.70

Publication bias in clinical trials due to statistical significance or direction of trial results. Cochrane Database Syst Rev (2009) 5.57

Outcome reporting in industry-sponsored trials of gabapentin for off-label use. N Engl J Med (2009) 5.15

Principles for international registration of protocol information and results from human trials of health related interventions: Ottawa statement (part 1). BMJ (2005) 4.73

Medicine. Moving toward transparency of clinical trials. Science (2008) 4.36

The challenge of subgroup analyses--reporting without distorting. N Engl J Med (2006) 4.19

Compliance with results reporting at ClinicalTrials.gov. N Engl J Med (2015) 4.17

Clinical trial registration--looking back and moving ahead. N Engl J Med (2007) 4.07

Is this clinical trial fully registered?--A statement from the International Committee of Medical Journal Editors. N Engl J Med (2005) 3.44

Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives. Health Technol Assess (2001) 3.32

Comparison of protocols and registry entries to published reports for randomised controlled trials. Cochrane Database Syst Rev (2011) 3.23

Selective reporting in clinical trials: analysis of trial protocols accepted by The Lancet. Lancet (2008) 2.76

Credibility of claims of subgroup effects in randomised controlled trials: systematic review. BMJ (2012) 2.69

Reporting discrepancies between the ClinicalTrials.gov results database and peer-reviewed publications. Ann Intern Med (2014) 2.67

Bias, spin, and misreporting: time for full access to trial protocols and results. PLoS Med (2008) 2.60

Social science. Publication bias in the social sciences: unlocking the file drawer. Science (2014) 2.51

Multiplicity in randomised trials II: subgroup and interim analyses. Lancet (2005) 2.34

Multiplicity in randomised trials I: endpoints and treatments. Lancet (2005) 2.32

Endpoints in adjuvant treatment trials: a systematic review of the literature in colon cancer and proposed definitions for future trials. J Natl Cancer Inst (2007) 2.11

False-positive results in clinical trials: multiple significance tests and the problem of unreported comparisons. J Natl Cancer Inst (1996) 1.66

The proposed rule for U.S. clinical trial registration and results submission. N Engl J Med (2014) 1.51

The effect of scientific misconduct on the results of clinical trials: a Delphi survey. Contemp Clin Trials (2005) 1.45

Multiplicities in cancer research: ubiquitous and necessary evils. J Natl Cancer Inst (2012) 1.07

Statistical power of negative randomized controlled trials presented at American Society for Clinical Oncology annual meetings. J Clin Oncol (2007) 1.05

Progression-free survival and time to progression as primary end points in advanced breast cancer: often used, sometimes loosely defined. Ann Oncol (2008) 1.01

Why publishing everything is more effective than selective publishing of statistically significant results. PLoS One (2014) 0.87

Research: increasing value, reducing waste - Authors' reply. Lancet (2014) 0.77