Published in J Cell Sci on July 17, 2007
A tense situation: forcing tumour progression. Nat Rev Cancer (2009) 7.80
The role of mechanical forces in tumor growth and therapy. Annu Rev Biomed Eng (2014) 1.40
Fast fluorescence microscopy for imaging the dynamics of embryonic development. HFSP J (2008) 1.34
Biomechanical regulation of cell orientation and fate. Oncogene (2008) 1.31
RARα2 expression confers myeloma stem cell features. Blood (2013) 1.15
Dickkopf-1 promotes hyperglycemia-induced accumulation of mesangial matrix and renal dysfunction. J Am Soc Nephrol (2009) 1.11
The regulation of organ size in Drosophila: physiology, plasticity, patterning and physical force. Organogenesis (2010) 1.07
Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem J (2011) 1.05
Induction of attachment-independent biofilm formation and repression of Hfq expression by low-fluid-shear culture of Staphylococcus aureus. Appl Environ Microbiol (2011) 1.04
Mechanical factors activate beta-catenin-dependent oncogene expression in APC mouse colon. HFSP J (2008) 1.01
Impact of stirred suspension bioreactor culture on the differentiation of murine embryonic stem cells into cardiomyocytes. BMC Cell Biol (2011) 0.93
The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro. BMC Microbiol (2014) 0.92
Resistance to fluid shear stress is a conserved biophysical property of malignant cells. PLoS One (2012) 0.91
Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation. J Biol Chem (2009) 0.89
Activation of NF-kappaB by fluid shear stress, but not TNF-alpha, requires focal adhesion kinase in osteoblasts. Bone (2010) 0.87
Roles of P21-activated kinases and associated proteins in epithelial wound healing. Int Rev Cell Mol Biol (2008) 0.85
The "artificial artery" as in vitro perfusion model. PLoS One (2013) 0.82
Mechanotransduction and nuclear function. Curr Opin Cell Biol (2016) 0.82
The assembly and function of perinuclear actin cap in migrating cells. Protoplasma (2017) 0.81
Perspective: Flicking with flow: Can microfluidics revolutionize the cancer research? Biomicrofluidics (2013) 0.81
Use of RNAlater in fluorescence-activated cell sorting (FACS) reduces the fluorescence from GFP but not from DsRed. BMC Res Notes (2010) 0.80
Comparing individual-based approaches to modelling the self-organization of multicellular tissues. PLoS Comput Biol (2017) 0.79
Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytes. J Musculoskelet Neuronal Interact (2013) 0.78
Daily application of low magnitude mechanical stimulus inhibits the growth of MDA-MB-231 breast cancer cells in vitro. Cancer Cell Int (2014) 0.77
Changes in cellular mechanical properties during onset or progression of colorectal cancer. World J Gastroenterol (2016) 0.76
Novel insights from 3D models: the pivotal role of physical symmetry in epithelial organization. Sci Rep (2015) 0.75
From competency to dormancy: a 3D model to study cancer cells and drug responsiveness. J Transl Med (2016) 0.75
Control of nuclear organization by F-actin binding proteins. Nucleus (2017) 0.75
Circulatory shear flow alters the viability and proliferation of circulating colon cancer cells. Sci Rep (2016) 0.75
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer. Cancer Res (2010) 2.87
Large-scale computations on histology images reveal grade-differentiating parameters for breast cancer. BMC Med Imaging (2006) 2.41
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol Cell Biol (2002) 2.19
SIRT1 and endocrine signaling. Trends Endocrinol Metab (2006) 2.17
A new algorithm for the evaluation of shotgun peptide sequencing in proteomics: support vector machine classification of peptide MS/MS spectra and SEQUEST scores. J Proteome Res (2003) 2.16
Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779. Cancer Res (2002) 1.93
The molecular basis of vitamin D receptor and beta-catenin crossregulation. Mol Cell (2006) 1.91
Retracted Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription. Cell (2006) 1.90
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Mol Biol Cell (2003) 1.86
Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol (2004) 1.80
Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155. Nat Med (2011) 1.79
Cyclin D1 determines mitochondrial function in vivo. Mol Cell Biol (2006) 1.75
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. J Biol Chem (2007) 1.71
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res (2006) 1.69
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA. Mol Cell Biol (2006) 1.65
ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. J Clin Invest (2012) 1.62
RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix. Mol Cell Biol (2002) 1.60
Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity. Cancer Res (2004) 1.58
Pathway-specific differences between tumor cell lines and normal and tumor tissue cells. Mol Cancer (2006) 1.51
Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. J Biol Chem (2002) 1.51
Trans-repression of beta-catenin activity by nuclear receptors. J Biol Chem (2003) 1.37
The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer. Oncogene (2005) 1.35
Predicting new indications for approved drugs using a proteochemometric method. J Med Chem (2012) 1.29
Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the α-tubulin tyrosination cycle. Cancer Res (2011) 1.28
An alternatively spliced cadherin-11 enhances human breast cancer cell invasion. Cancer Res (2002) 1.26
ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo. Cancer Res (2007) 1.23
Switch-like genes populate cell communication pathways and are enriched for extracellular proteins. BMC Genomics (2008) 1.21
Enhancing the Curie temperature of ferromagnetic semiconductor (Ga,Mn)As to 200 K via nanostructure engineering. Nano Lett (2011) 1.20
Attenuation of Forkhead signaling by the retinal determination factor DACH1. Proc Natl Acad Sci U S A (2010) 1.20
Targeting aurora kinases as therapy in multiple myeloma. Blood (2007) 1.19
Riboproteomics of the hepatitis C virus internal ribosomal entry site. J Proteome Res (2004) 1.19
Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs. BMC Med Genomics (2009) 1.18
G-DOC: a systems medicine platform for personalized oncology. Neoplasia (2011) 1.18
Metabolism of fostamatinib, the oral methylene phosphate prodrug of the spleen tyrosine kinase inhibitor R406 in humans: contribution of hepatic and gut bacterial processes to the overall biotransformation. Drug Metab Dispos (2010) 1.17
Wnt/beta-catenin and retinoic acid receptor signaling pathways interact to regulate chondrocyte function and matrix turnover. J Biol Chem (2009) 1.16
Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes. Hepatology (2004) 1.15
Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells. Mol Endocrinol (2006) 1.15
The control of axillary meristem fate in the maize ramosa pathway. Development (2010) 1.14
Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials. Crit Rev Eukaryot Gene Expr (2011) 1.09
Dachshund binds p53 to block the growth of lung adenocarcinoma cells. Cancer Res (2013) 1.07
PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells. Oncogene (2002) 1.05
Retrovirally delivered random cyclic Peptide libraries yield inhibitors of interleukin-4 signaling in human B cells. J Biol Chem (2002) 1.04
The CUBLAS and CULA based GPU acceleration of adaptive finite element framework for bioluminescence tomography. Opt Express (2010) 1.04
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets. BMC Bioinformatics (2007) 1.03
Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway. Exp Cell Res (2010) 1.02
Clinical characteristics and treatment of gestational trophoblastic tumor with vaginal metastasis. Gynecol Oncol (2002) 1.02
Heterogeneous breast tumoroids: An in vitro assay for investigating cellular heterogeneity and drug delivery. J Biomol Screen (2006) 1.01
Nuclear receptor modifications and endocrine cell proliferation. J Steroid Biochem Mol Biol (2003) 0.99
Genome-wide multi-omics profiling of colorectal cancer identifies immune determinants strongly associated with relapse. Front Genet (2013) 0.99
The role of cadherin, beta-catenin, and AP-1 in retinoid-regulated carcinoma cell differentiation and proliferation. J Biol Chem (2002) 0.99
Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis. PLoS One (2012) 0.98
Vascular leakage in chick embryos after expression of a secreted binding protein for fibroblast growth factors. Lab Invest (2005) 0.97
Big data: the next frontier for innovation in therapeutics and healthcare. Expert Rev Clin Pharmacol (2014) 0.97
Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways. Mol Cancer Ther (2005) 0.96
Control of TCF-4 expression by VDR and vitamin D in the mouse mammary gland and colorectal cancer cell lines. PLoS One (2009) 0.96
Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway. Oncogene (2003) 0.96
Post-transcriptional regulation of cadherin-11 expression by GSK-3 and beta-catenin in prostate and breast cancer cells. PLoS One (2009) 0.95
βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin. Hepatology (2015) 0.95
Small molecule metabolite extraction strategy for improving LC/MS detection of cancer cell metabolome. J Biomol Tech (2011) 0.95
The farnesyltransferase inhibitor L744832 potentiates UCN-01-induced apoptosis in human multiple myeloma cells. Clin Cancer Res (2005) 0.93
Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells. Cancer Res (2005) 0.92
Large-scale integration of microarray data reveals genes and pathways common to multiple cancer types. Int J Cancer (2011) 0.92
Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases. Inflamm Bowel Dis (2012) 0.92
miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget (2014) 0.92
Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. Nat Commun (2013) 0.91
Role of Sox-9, ER81 and VE-cadherin in retinoic acid-mediated trans-differentiation of breast cancer cells. PLoS One (2008) 0.91
Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model. Cell Cycle (2010) 0.91
Purely electronic switching with high uniformity, resistance tunability, and good retention in Pt-dispersed SiO2 thin films for ReRAM. Adv Mater (2011) 0.91
Biomarkers of WNT signaling. Cancer Biomark (2007) 0.91
Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26. J Cancer (2010) 0.90
RepurposeVS: A Drug Repurposing-Focused Computational Method for Accurate Drug-Target Signature Predictions. Comb Chem High Throughput Screen (2015) 0.90
Detection of apoptosis based on the interaction between annexin V and phosphatidylserine. Anal Chem (2009) 0.89
Up-regulation of fibroblast growth factor-binding protein, by beta-catenin during colon carcinogenesis. Cancer Res (2003) 0.88
Arabidopsis CPR5 independently regulates seed germination and postgermination arrest of development through LOX pathway and ABA signaling. PLoS One (2011) 0.88
Use of MEDUSA-based data analysis and capillary HPLC-ion-trap mass spectrometry to examine complex immunoaffinity extracts of RBAp48. J Proteome Res (2003) 0.87
Multiple functional categories of proteins identified in an in vitro cellular ubiquitin affinity extract using shotgun peptide sequencing. J Proteome Res (2003) 0.87
Host sequence motifs shared by HIV predict response to antiretroviral therapy. BMC Med Genomics (2009) 0.87
A trust region method in adaptive finite element framework for bioluminescence tomography. Opt Express (2010) 0.87
Evaluation of the simplified spherical harmonics approximation in bioluminescence tomography through heterogeneous mouse models. Opt Express (2010) 0.87
Vitamin D and the regulation of Wnt/beta-catenin signaling and innate immunity in colorectal cancer. Nutr Rev (2007) 0.86
Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types. BMC Bioinformatics (2010) 0.86
Fast-specific tomography imaging via Cerenkov emission. Mol Imaging Biol (2012) 0.85
Putative biomarkers and targets of estrogen receptor negative human breast cancer. Int J Mol Sci (2011) 0.85
Sertoli-Leydig cell tumor presenting hyperestrogenism in a postmenopausal woman: a case report and review of the literature. Taiwan J Obstet Gynecol (2012) 0.85
Alteration in protein expression in estrogen receptor alpha-negative human breast cancer tissues indicates a malignant and metastatic phenotype. Clin Exp Metastasis (2010) 0.85
Harnessing Polypharmacology with Computer-Aided Drug Design and Systems Biology. Curr Pharm Des (2016) 0.85
Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Oncotarget (2014) 0.85
Retinoic acid mediates regulation of network formation by COUP-TFII and VE-cadherin expression by TGFbeta receptor kinase in breast cancer cells. PLoS One (2010) 0.85
Human and mouse switch-like genes share common transcriptional regulatory mechanisms for bimodality. BMC Genomics (2008) 0.85
The effect of intermittent hypoxia on bodyweight, serum glucose and cholesterol in obesity mice. Pak J Biol Sci (2008) 0.85
Trichoderone, a novel cytotoxic cyclopentenone and cholesta-7, 22-diene-3 beta, 5 alpha, 6 beta-triol, with new activities from the marine-derived fungus Trichoderma sp. J Ind Microbiol Biotechnol (2010) 0.85
Novel stromal biomarkers in human breast cancer tissues provide evidence for the more malignant phenotype of estrogen receptor-negative tumors. J Biomed Biotechnol (2011) 0.84
The type 1 insulin-like growth factor receptor and resistance to DACH1. Cell Cycle (2011) 0.83
Dissecting the roles of checkpoint kinase 1/CDC2 and mitogen-activated protein kinase kinase 1/2/extracellular signal-regulated kinase 1/2 in relation to 7-hydroxystaurosporine-induced apoptosis in human multiple myeloma cells. Mol Pharmacol (2006) 0.83
Loss of FHIT expression in breast cancer is correlated with poor prognostic markers. Cancer Epidemiol Biomarkers Prev (2005) 0.83