PPAR-γ agonism as a modulator of mood: proof-of-concept for pioglitazone in bipolar depression.

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Published in CNS Drugs on June 01, 2014

Authors

David E Kemp1, Martha Schinagle, Keming Gao, Carla Conroy, Stephen J Ganocy, Faramarz Ismail-Beigi, Joseph R Calabrese

Author Affiliations

1: University Hospitals Case Medical Center, Case Western Reserve University, 10524 Euclid Ave., 12th Floor, Cleveland, OH, 44106, USA, kemp.david@gmail.com.

Associated clinical trials:

Pioglitazone for the Treatment of Bipolar Disorder and Comorbid Metabolic Syndrome or Insulin Resistance | NCT00835120

Brexpiprazole Treatment for Bipolar I Depression | NCT04569448

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