Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression.

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Published in J Biol Chem on April 09, 2014

Authors

Madalena Barroso1, Cristina Florindo2, Hermann Kalwa3, Zélia Silva4, Anton A Turanov5, Bradley A Carlson6, Isabel Tavares de Almeida7, Henk J Blom8, Vadim N Gladyshev5, Dolph L Hatfield6, Thomas Michel3, Rita Castro7, Joseph Loscalzo3, Diane E Handy9

Author Affiliations

1: From the Cardiovascular and the Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL) and.
2: the Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL) and.
3: From the Cardiovascular and.
4: the Chronic Diseases Research Center, Departamento de Imunologia, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1099-085 Lisbon, Portugal.
5: Genetics Divisions, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115.
6: the Molecular Biology of Selenium Section, Mouse Cancer Genetics Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, and.
7: the Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL) and Department of Biochemistry and Human Biology, Faculty of Pharmacy, University of Lisbon, 1649-004 Lisbon, Portugal.
8: the Department of General Pediatrics, Center for Pediatrics and Adolescent Medicine, University Hospital, 79106 Freiburg, Germany.
9: From the Cardiovascular and dhandy@rics.bwh.harvard.edu.

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