Published in Proc Natl Acad Sci U S A on April 14, 2014
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
Autophagy and apoptosis in liver injury. Cell Cycle (2015) 0.92
Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling. Autophagy (2015) 0.87
Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog (2015) 0.86
HCV induces the expression of Rubicon and UVRAG to temporally regulate the maturation of autophagosomes and viral replication. PLoS Pathog (2015) 0.86
Mitochondrial dynamics and viral infections: A close nexus. Biochim Biophys Acta (2015) 0.84
Hepatitis C virus and autophagy. Biol Chem (2015) 0.84
MiRNA-30a inhibits AECs-II apoptosis by blocking mitochondrial fission dependent on Drp-1. J Cell Mol Med (2014) 0.84
miR-361-regulated prohibitin inhibits mitochondrial fission and apoptosis and protects heart from ischemia injury. Cell Death Differ (2014) 0.84
Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling. J Virol (2015) 0.81
Hepatitis C Virus. Strategies to Evade Antiviral Responses. Future Virol (2015) 0.81
A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection. Cell Syst (2016) 0.81
Innate immune evasion strategies of DNA and RNA viruses. Curr Opin Microbiol (2016) 0.81
Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells. PLoS Pathog (2017) 0.80
Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am J Cancer Res (2015) 0.80
Stealing the Keys to the Kitchen: Viral Manipulation of the Host Cell Metabolic Network. Trends Microbiol (2015) 0.80
SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway. Cancer Lett (2016) 0.80
Reconciling West Nile virus with the autophagic pathway. Autophagy (2015) 0.79
Autophagy and checkpoints for intracellular pathogen defense. Curr Opin Gastroenterol (2015) 0.78
Pathologic and therapeutic implications for the cell biology of parkin. Mol Cell Neurosci (2015) 0.78
Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response. Viruses (2016) 0.77
Viral (hepatitis C virus, hepatitis B virus, HIV) persistence and immune homeostasis. Immunology (2014) 0.77
Transcriptome markers of viral persistence in naturally-infected andes virus (bunyaviridae) seropositive long-tailed pygmy rice rats. PLoS One (2015) 0.77
Mitophagy in TGEV infection counteracts oxidative stress and apoptosis. Oncotarget (2016) 0.77
Autophagy in HCV infection: keeping fat and inflammation at bay. Biomed Res Int (2014) 0.76
The role of autophagy in microbial infection and immunity. Immunotargets Ther (2015) 0.76
Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission. Virology (2016) 0.76
Insights into antiviral innate immunity revealed by studying hepatitis C virus. Cytokine (2015) 0.76
Retracted Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am J Cancer Res (2015) 0.75
Increased Mitochondrial Genetic Diversity in Persons Infected With Hepatitis C Virus. Cell Mol Gastroenterol Hepatol (2016) 0.75
Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation. Sci Rep (2016) 0.75
Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun (2016) 0.75
HCV-Induced Oxidative Stress: Battlefield-Winning Strategy. Oxid Med Cell Longev (2016) 0.75
Porcine reproductive and respiratory syndrome virus triggers mitochondrial fission and mitophagy to attenuate apoptosis. Oncotarget (2016) 0.75
Doxycycline Induces Mitophagy and Suppresses Production of Interferon-β in IPEC-J2 Cells. Front Cell Infect Microbiol (2017) 0.75
Hepatitis C Virus Exploits Death Receptor 6-mediated Signaling Pathway to Facilitate Viral Propagation. Sci Rep (2017) 0.75
Coxsackievirus B escapes the infected cell in ejected mitophagosomes. J Virol (2017) 0.75
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol (2005) 9.11
The lipid droplet is an important organelle for hepatitis C virus production. Nat Cell Biol (2007) 8.98
Replication of hepatitis C virus. Nat Rev Microbiol (2007) 8.31
Mitochondrial fission, fusion, and stress. Science (2012) 7.45
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J Virol (2002) 6.69
Mitochondrial dynamics and apoptosis. Genes Dev (2008) 6.07
Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases. Hum Mol Genet (2009) 5.15
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria. Proc Natl Acad Sci U S A (2008) 4.89
Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci (2008) 4.32
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J Cell Biol (2010) 3.91
Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol (2006) 3.84
Mitochondrial dynamics in mammalian health and disease. Physiol Rev (2009) 3.59
Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology (2006) 3.52
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation. Proc Natl Acad Sci U S A (2011) 3.49
Fusion and fission: interlinked processes critical for mitochondrial health. Annu Rev Genet (2012) 3.47
Mitochondria in innate immune responses. Nat Rev Immunol (2011) 3.31
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc Natl Acad Sci U S A (2001) 3.06
Stealth and cunning: hepatitis B and hepatitis C viruses. J Virol (2005) 2.94
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway. J Virol (2002) 2.39
Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J Biol Chem (2005) 2.21
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell (2013) 2.21
Hepatitis C virus hijacks host lipid metabolism. Trends Endocrinol Metab (2009) 2.05
The interplay between mitochondrial dynamics and mitophagy. Antioxid Redox Signal (2011) 2.05
Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway. EMBO Rep (2009) 1.97
Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: ultrastructural and biochemical findings. Am J Gastroenterol (1999) 1.81
Pathophysiology of hepatitis C virus infection and related liver disease. Trends Microbiol (2004) 1.75
New insights into the function and regulation of mitochondrial fission. Biochim Biophys Acta (2013) 1.70
Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J Virol (2007) 1.61
Hepatitis C virus infection induces apoptosis through a Bax-triggered, mitochondrion-mediated, caspase 3-dependent pathway. J Virol (2008) 1.60
Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage. J Cell Biol (2012) 1.44
Role of oxysterol binding protein in hepatitis C virus infection. J Virol (2009) 1.43
Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication. J Virol (2005) 1.39
Hepatitis C virus core protein increases mitochondrial ROS production by stimulation of Ca2+ uniporter activity. FASEB J (2007) 1.23
Hepatitis C virus-linked mitochondrial dysfunction promotes hypoxia-inducible factor 1 alpha-mediated glycolytic adaptation. J Virol (2010) 1.23
Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication. J Virol (2005) 1.22
Hepatitis C virus protein expression causes calcium-mediated mitochondrial bioenergetic dysfunction and nitro-oxidative stress. Hepatology (2007) 1.10
Role of p38 MAPK and RNA-dependent protein kinase (PKR) in hepatitis C virus core-dependent nuclear delocalization of cyclin B1. J Biol Chem (2006) 1.10
Mitochondrial dysfunction in hepatitis C. J Clin Gastroenterol (2005) 1.09
Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. PLoS Pathog (2013) 1.07
Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis. PLoS Pathog (2013) 1.00
Effects of hypolipidemic agent nordihydroguaiaretic acid on lipid droplets and hepatitis C virus. Hepatology (2011) 1.00
New drug targets for hepatitis C and other Flaviviridae viruses. Infect Disord Drug Targets (2009) 0.81
A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med (2006) 7.35
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. J Clin Invest (2009) 5.09
Sexual transmission of hepatitis C virus among monogamous heterosexual couples: the HCV partners study. Hepatology (2013) 3.35
Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects. J Infect Dis (2005) 2.91
Hepatitis B e antigen in sera from individuals infected with hepatitis B virus of genotype G. Hepatology (2002) 2.85
Cardiac perforation and lead dislodgement after implantation of a MR-conditional pacing lead: a single-center experience. Pacing Clin Electrophysiol (2013) 2.77
Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment. Gastroenterology (2004) 2.64
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway. J Virol (2002) 2.39
Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. J Biol Chem (2004) 2.29
Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. J Am Coll Cardiol (2012) 2.18
Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol (2005) 2.14
Hepatitis C virus hijacks host lipid metabolism. Trends Endocrinol Metab (2009) 2.05
Epidemiologic and virologic characteristics of hepatitis B virus genotype B having the recombination with genotype C. Gastroenterology (2003) 2.02
A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patients. Gastroenterology (2005) 1.76
Myocardial AKT: the omnipresent nexus. Physiol Rev (2011) 1.76
Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J Virol (2007) 1.61
Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens. Hepatology (2006) 1.60
Cell-free replication of the hepatitis C virus subgenomic replicon. J Virol (2002) 1.52
Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease. J Biol Chem (2003) 1.45
Role of oxysterol binding protein in hepatitis C virus infection. J Virol (2009) 1.43
Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication. J Virol (2005) 1.39
Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C. Hepatology (2007) 1.38
Characteristics of hepatitis B virus isolates of genotype G and their phylogenetic differences from the other six genotypes (A through F). J Virol (2002) 1.36
Assessment of immunogenic potential of Vero adapted formalin inactivated vaccine derived from novel ECSA genotype of Chikungunya virus. Vaccine (2009) 1.32
Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion. J Biol Chem (2005) 1.30
A new locus for autosomal recessive congenital cataract identified in a Pakistani family. Mol Vis (2010) 1.30
Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis. Eur Heart J (2011) 1.28
Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis. Hepatology (2007) 1.27
Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3. Biochem Pharmacol (2002) 1.27
Model for end-stage liver disease (MELD) exception for hepatopulmonary syndrome. Liver Transpl (2006) 1.26
Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication. Virology (2005) 1.24
Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication. J Virol (2005) 1.22
Rejuvenation of human cardiac progenitor cells with Pim-1 kinase. Circ Res (2013) 1.20
Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol (2007) 1.19
Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function. J Virol (2002) 1.18
Role of phosphatidylinositol 4-phosphate (PI4P) and its binding protein GOLPH3 in hepatitis C virus secretion. J Biol Chem (2012) 1.15
Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice. J Transl Med (2013) 1.14
Eight genotypes (A-H) of hepatitis B virus infecting patients from San Francisco and their demographic, clinical, and virological characteristics. J Med Virol (2004) 1.13
Epidemiological and sequence differences between two subtypes (Ae and Aa) of hepatitis B virus genotype A. J Gen Virol (2004) 1.12
A case-control study for differences among hepatitis B virus infections of genotypes A (subtypes Aa and Ae) and D. Hepatology (2004) 1.10
Bone marrow derived mesenchymal stem cells from aged mice have reduced wound healing, angiogenesis, proliferation and anti-apoptosis capabilities. Cell Biol Int (2012) 1.08
Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. PLoS Pathog (2013) 1.07
Model for end-stage liver disease (MELD) exception guidelines. Liver Transpl (2006) 1.07
Molecular epidemiology of hepatitis C virus subtype 3a in injecting drug users. J Med Virol (2006) 1.06
Nucleolar stress is an early response to myocardial damage involving nucleolar proteins nucleostemin and nucleophosmin. Proc Natl Acad Sci U S A (2011) 1.04
Cell surface expression of major histocompatibility complex class I molecules is reduced in hepatitis C virus subgenomic replicon-expressing cells. J Virol (2003) 1.04
Immunogenicity of a recombinant envelope domain III protein of dengue virus type-4 with various adjuvants in mice. Vaccine (2008) 1.03
T1653 mutation in the box alpha increases the risk of hepatocellular carcinoma in patients with chronic hepatitis B virus genotype C infection. Clin Infect Dis (2005) 1.02
Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein. J Biol Chem (2011) 1.02
The degree of readiness of selected biomarkers for the early detection of hepatocellular carcinoma: notes from a recent workshop. Cancer Biomark (2008) 1.01
Model for end-stage liver disease (MELD) exception for polycystic liver disease. Liver Transpl (2006) 1.01
Cost effectiveness of entecavir versus lamivudine with adefovir salvage in HBeAg-positive chronic hepatitis B. Pharmacoeconomics (2007) 1.00
Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis. PLoS Pathog (2013) 1.00
Effects of hypolipidemic agent nordihydroguaiaretic acid on lipid droplets and hepatitis C virus. Hepatology (2011) 1.00
Enhanced hepatic differentiation of mesenchymal stem cells after pretreatment with injured liver tissue. Differentiation (2010) 0.98
Model for end-stage liver disease (MELD) exception for bacterial cholangitis. Liver Transpl (2006) 0.98
Characterization of the mitochondrial association of hepatitis B virus X protein, HBx. Mitochondrion (2002) 0.98
Mesenchymal stem cells conditioned with glucose depletion augments their ability to repair-infarcted myocardium. J Cell Mol Med (2012) 0.95
Adenosine inhibits chemotaxis and induces hepatocyte-specific genes in bone marrow mesenchymal stem cells. Hepatology (2010) 0.94
Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress. J Virol (2007) 0.94
Autosomal recessive congenital cataract in consanguineous Pakistani families is associated with mutations in GALK1. Mol Vis (2010) 0.93
Nail-gun narcolepsy. Lancet (2009) 0.93
Survival after liver transplantation in patients with hepatic iron overload: the national hemochromatosis transplant registry. Gastroenterology (2005) 0.92
Hepatitis C virus stimulates low-density lipoprotein receptor expression to facilitate viral propagation. J Virol (2013) 0.90
Mycophenolate mofetil in autoimmune hepatitis patients not responsive or intolerant to standard immunosuppressive therapy. Clin Gastroenterol Hepatol (2007) 0.90
Future therapies for hepatitis C. Antivir Ther (2006) 0.90
Development and evaluation of antigen capture ELISA for early clinical diagnosis of chikungunya. Diagn Microbiol Infect Dis (2009) 0.89
Neuropsychology of prefrontal cortex. Indian J Psychiatry (2008) 0.89
Differential proteome analysis of Chikungunya virus-infected new-born mice tissues reveal implication of stress, inflammatory and apoptotic pathways in disease pathogenesis. Proteomics (2011) 0.89
Chronic HBV infection outside treatment guidelines: is treatment needed? Antivir Ther (2012) 0.89
Model for end-stage liver disease (MELD) exception for cholangiocarcinoma or biliary dysplasia. Liver Transpl (2006) 0.89
Hepatocellular carcinoma: molecular and genomic guideline for the clinician. Clin Liver Dis (2011) 0.88
Simple but highly effective three-dimensional chemical-feature-based pharmacophore model for diketo acid derivatives as hepatitis C virus RNA-dependent RNA polymerase inhibitors. J Med Chem (2005) 0.88
Model for end-stage liver disease (MELD) exception for portopulmonary hypertension. Liver Transpl (2006) 0.87
Diode-pumped, high-average-power femtosecond Cr3+ :LiCAF laser. Opt Lett (2007) 0.87
Two-step affinity purification of the hepatitis C virus ribonucleoprotein complex. RNA (2004) 0.87
Pim-1 kinase inhibits pathological injury by promoting cardioprotective signaling. J Mol Cell Cardiol (2011) 0.86
Technical standards for hepatitis B virus X protein (HBx) research. Hepatology (2015) 0.86
Phosphoinositides in the hepatitis C virus life cycle. Viruses (2012) 0.86
Reliability and predictive validity of a hepatitis-related symptom inventory in HIV-infected individuals referred for Hepatitis C treatment. AIDS Res Ther (2011) 0.85
Hepatic encephalopathy is associated with significantly increased mortality among patients awaiting liver transplantation. Liver Transpl (2014) 0.85
Generation of 287 W, 5.5 ps pulses at 78 MHz repetition rate from a cryogenically cooled Yb:YAG amplifier seeded by a fiber chirped-pulse amplification system. Opt Lett (2008) 0.85
Management of ascites due to gastrointestinal malignancy. Ann Saudi Med (2009) 0.85
Safety and efficacy of viramidine versus ribavirin in ViSER2: randomized, double-blind study in therapy-naive hepatitis C patients. J Hepatol (2009) 0.85
Classifying genotype F of hepatitis B virus into F1 and F2 subtypes. World J Gastroenterol (2005) 0.85
Nitric oxide augments mesenchymal stem cell ability to repair liver fibrosis. J Transl Med (2012) 0.84
Frequent coinfection with hepatitis B virus strains of distinct genotypes detected by hybridization with type-specific probes immobilized on a solid-phase support. J Virol Methods (2003) 0.83
Model for end-stage liver disease (MELD) exception for unusual metabolic liver diseases. Liver Transpl (2006) 0.83
A randomized controlled trial of thymalfasin plus transarterial chemoembolization for unresectable hepatocellular carcinoma. Hepatol Int (2009) 0.83
To "be" or not to "be": that is the question. Am J Gastroenterol (2009) 0.82
Preconditioning diabetic mesenchymal stem cells with myogenic medium increases their ability to repair diabetic heart. Stem Cell Res Ther (2013) 0.82
Model for end-stage liver disease (MELD) exception for Budd-Chiari syndrome. Liver Transpl (2006) 0.82
Inhibition of Hec1 as a novel approach for treatment of primary liver cancer. Cancer Chemother Pharmacol (2014) 0.81
Differential toxicity profile of ricin isoforms correlates with their glycosylation levels. Toxicology (2011) 0.81