Published in J Biol Chem on August 25, 1989
Evidence for involvement of protein kinase C in the cellular response to interferon alpha. Proc Natl Acad Sci U S A (1990) 1.77
Transmembrane signaling by interferon alpha involves diacylglycerol production and activation of the epsilon isoform of protein kinase C in Daudi cells. Proc Natl Acad Sci U S A (1991) 1.19
A collection of mRNA species that are inducible in the RAW 264.7 mouse macrophage cell line by gamma interferon and other agents. Mol Cell Biol (1992) 1.07
Interferon alpha activates NF-kappaB in JAK1-deficient cells through a TYK2-dependent pathway. J Biol Chem (2005) 1.01
Disruption by interferon-alpha of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor alpha- and beta-chains. J Clin Invest (1994) 0.94
Interferon alpha induces protein kinase C-epsilon (PKC-epsilon) gene expression and a 4.7-kb PKC-epsilon-related transcript. Proc Natl Acad Sci U S A (1993) 0.89
Characterization of two independent mechanisms by which interferon-induced gene expression is down regulated. Cell Regul (1990) 0.77
A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med (1995) 2.88
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus. Nature (1986) 2.64
Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell (1997) 2.64
Role of tumor necrosis factor alpha in innate resistance to mouse pulmonary infection with Pseudomonas aeruginosa. Infect Immun (1995) 1.61
Differential inhibition of IL-1 and TNF-alpha mRNA expression by agents which block second messenger pathways in murine macrophages. J Immunol (1988) 1.55
A Th1-associated increase in tumor necrosis factor alpha expression in the spleen correlates with resistance to blood-stage malaria in mice. Infect Immun (1996) 1.52
Novel integrase-defective lentiviral episomal vectors for gene transfer. Hum Gene Ther (2004) 1.52
Heterogeneity of hematopoietic cells immortalized by v-myc/v-raf recombinant retrovirus infection of bone marrow or fetal liver. J Natl Cancer Inst (1989) 1.44
Lung disease in mice with cystic fibrosis. J Clin Invest (1997) 1.44
Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine. J Biol Chem (1997) 1.33
Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA. Proc Natl Acad Sci U S A (1990) 1.31
Two distinct regions in the 3' untranslated region of tumor necrosis factor alpha mRNA form complexes with macrophage proteins. Mol Cell Biol (1996) 1.30
A murine macrophage cell line, immortalized by v-raf and v-myc oncogenes, exhibits normal macrophage functions. Eur J Immunol (1987) 1.25
In vivo regulation of nitric oxide production by tumor necrosis factor alpha and gamma interferon, but not by interleukin-4, during blood stage malaria in mice. Infect Immun (1996) 1.24
Genetic resistance/susceptibility to mycobacteria: phenotypic expression in bone marrow derived macrophage lines. J Leukoc Biol (1991) 1.24
Attenuation of MHC class II expression in macrophages infected with Mycobacterium bovis bacillus Calmette-Guérin involves class II transactivator and depends on the Nramp1 gene. J Immunol (1999) 1.23
Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA. Nucleic Acids Res (2001) 1.22
Nitric oxide expression in the spleen, but not in the liver, correlates with resistance to blood-stage malaria in mice. J Immunol (1995) 1.20
Expression and role of p75 interleukin 2 receptor on human monocytes. J Exp Med (1990) 1.19
Potential requirement of a functional double-stranded RNA-dependent protein kinase (PKR) for the tumoricidal activation of macrophages by lipopolysaccharide or IFN-alpha beta, but not IFN-gamma. J Immunol (1995) 1.17
Lipopolysaccharide-related stimuli induce expression of the secretory leukocyte protease inhibitor, a macrophage-derived lipopolysaccharide inhibitor. Infect Immun (1998) 1.16
Interleukin 1 induction of the c-jun promoter. Proc Natl Acad Sci U S A (1993) 1.15
Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7. J Exp Med (1995) 1.14
Transforming growth factor beta downregulates interleukin-1 (IL-1)-induced IL-6 production by human monocytes. Blood (1990) 1.13
Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes. Cancer Res (1999) 1.12
Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis. Eur J Immunol (2001) 1.11
Interferon activates macrophages to produce plasminogen activator. J Interferon Res (1982) 1.11
Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA. Nucleic Acids Res (1998) 1.10
Endotoxin requirement for macrophage activation by lymphokines in a rapid microcytotoxicity assay. J Immunol Methods (1980) 1.10
Augmentation of GG2EE macrophage cell line-mediated anti-Candida activity by gamma interferon, tumor necrosis factor, and interleukin-1. Infect Immun (1990) 1.10
Genetic control of innate resistance to mycobacterial infections. Immunol Today (1991) 1.10
Mouse models of chronic lung infection with Pseudomonas aeruginosa: models for the study of cystic fibrosis. Pediatr Pulmonol (2000) 1.09
Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid. Biochem Biophys Res Commun (1996) 1.08
Dexamethasone inhibits the induction of monocyte chemotactic-activating factor production by IL-1 or tumor necrosis factor. J Immunol (1991) 1.05
T-helper 1-like subset selection in Mycobacterium bovis bacillus Calmette-Guérin-infected resistant and susceptible mice. Immunology (1994) 1.05
Tumor necrosis factor-alpha-dependent production of reactive nitrogen intermediates mediates IFN-gamma plus IL-2-induced murine macrophage tumoricidal activity. J Immunol (1992) 1.05
Pleiotropic effects of transforming growth factor-beta on cells of the immune system. Ann N Y Acad Sci (1993) 1.05
Interferon-gamma upregulates interleukin-8 gene expression in human monocytic cells by a posttranscriptional mechanism. Blood (1994) 1.05
Impaired ability of Cftr knockout mice to control lung infection with Pseudomonas aeruginosa. Am J Respir Crit Care Med (1998) 1.04
IL-2 induces IL-6 production in human monocytes. J Immunol (1992) 1.03
IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes. J Immunol (1993) 1.02
Nitrite production by macrophages derived from BCG-resistant and -susceptible congenic mouse strains in response to IFN-gamma and infection with BCG. Immunology (1994) 1.02
Cytokine gene expression during the generation of human lymphokine-activated killer cells: early induction of interleukin 1 beta by interleukin 2. Cancer Res (1989) 1.02
TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway. Am J Physiol Lung Cell Mol Physiol (2005) 1.02
Generation of macrophage cell line from fresh bone marrow cells with a myc/raf recombinant retrovirus. Cancer Biochem Biophys (1989) 1.01
High macrophage lipoprotein lipase expression and secretion are associated in inbred murine strains with susceptibility to atherosclerosis. Arterioscler Thromb (1993) 1.01
Regulation of inducible nitric oxide synthase expression in IFN-gamma-treated murine macrophages cultured under hypoxic conditions. J Immunol (1996) 1.00
Posttranscriptional control of human gamma interferon gene expression in transfected mouse fibroblasts. Mol Cell Biol (1986) 0.99
c-fos mRNA expression in macrophages is downregulated by interferon-gamma at the posttranscriptional level. Mol Cell Biol (1991) 0.98
Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities. Arterioscler Thromb (1993) 0.98
The tryptophan catabolite picolinic acid selectively induces the chemokines macrophage inflammatory protein-1 alpha and -1 beta in macrophages. J Immunol (2000) 0.97
Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes. Blood (1994) 0.97
Mechanism of interference mediated by human parainfluenza virus type 3 infection. J Virol (2000) 0.97
Mechanisms of lymphocyte activation: linkage between early protein synthesis and late lymphocyte proliferation. J Immunol (1980) 0.97
Purification and characterization of a human lung tumor-associated antigen. J Natl Cancer Inst (1978) 0.97
Potent activation of mouse macrophages by recombinant interferon-gamma. Cancer Res (1984) 0.96
Macrophages as regulators of immune responses against tumors. Adv Exp Med Biol (1979) 0.96
Characterization of IL-2 receptor expression and function on murine macrophages. J Immunol (1990) 0.96
Regulation of nitric-oxide synthase mRNA expression by interferon-gamma and picolinic acid. J Biol Chem (1994) 0.95
Molecular genetics of inherited susceptibility to intracellular parasites. Behring Inst Mitt (1991) 0.94
Acquired resistance but not innate resistance to Mycobacterium bovis bacillus Calmette-Guérin is compromised by interleukin-12 ablation. Infect Immun (1998) 0.94
Disruption by interferon-alpha of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor alpha- and beta-chains. J Clin Invest (1994) 0.94
Assessment of lymphokine profiles in activated lymphocytes by semiquantitative PCR. J Immunol Methods (1993) 0.93
Augmentation of c-fos mRNA expression by activators of protein kinase C in fresh, terminally differentiated resting macrophages. Mol Cell Biol (1987) 0.93
Picolinic acid, a catabolite of tryptophan, as the second signal in the activation of IFN-gamma-primed macrophages. J Immunol (1990) 0.92
The effect of cytochalasin B, colchicine and vinblastine on the adhesion of Trichomonas vaginalis to glass surfaces. Int J Parasitol (1975) 0.92
Prolonged adjuvant stimulation in germ-free BALB-c mice: development of plasma cell neoplasia. Immunology (1969) 0.91
Cystic fibrosis lung disease following infection with Pseudomonas aeruginosa in Cftr knockout mice using novel non-invasive direct pulmonary infection technique. Lab Anim (2005) 0.91
Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection. Clin Exp Immunol (2014) 0.91
Interleukin-2 and human monocyte activation. J Leukoc Biol (1995) 0.90
Assessment of mycobacterial infection and multiplication in macrophages by polymerase chain reaction. J Immunol Methods (1993) 0.90
Tumoricidal alveolar macrophage and tumor infiltrating macrophage cell lines. Int J Cancer (1991) 0.90
An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells. Am J Physiol (1998) 0.90
Results of the second international study on the W.H.O. alpha-foetoprotein standard. J Biol Stand (1978) 0.90
Erythroid differentiation and modulation of c-myc expression induced by antineoplastic drugs in the human leukemic cell line K562. Cancer Res (1987) 0.90
Airway surface liquid composition in mice. Am J Physiol Lung Cell Mol Physiol (2000) 0.89
Lipopolysaccharide, but not IFN-gamma, down-regulates c-fms mRNA proto-oncogene expression in murine macrophages. J Immunol (1990) 0.89
Further studies on a human lung tumor-associated antigen. Comparison of antigens from different tumors. J Biol Chem (1979) 0.89
Inhibition of retroviral mRNA expression in the murine macrophage cell line GG2EE by biologic response modifiers. J Immunol (1988) 0.89
Serum alpha-fetoprotein as a biochemical marker for hepatocellular carcinoma. Cancer Res (1972) 0.88
Ribosomal RNA metabolism in macrophages. Curr Top Microbiol Immunol (1992) 0.88
Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells. Proc Natl Acad Sci U S A (1996) 0.88
Interferon-alpha, -beta, and -gamma augment the levels of rRNA precursors in peritoneal macrophages but not in macrophage cell lines and fibroblasts. J Immunol (1987) 0.87
Phenotypic difference between Bcg(r) and Bcg(s) macrophages is related to differences in protein-kinase-C-dependent signalling. Eur J Biochem (1998) 0.87
Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages. J Immunol (1993) 0.87