A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs.

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Published in Ther Adv Vaccines on January 01, 2014

Authors

Karl-Josef Kallen1, Andreas Theß2

Author Affiliations

1: CureVac GmbH, Paul Ehrlich Str. 15, 72076 Tübingen, Germany.
2: CureVac GmbH, Tübingen, Germany.

Associated clinical trials:

Autologous TriMix-DC Therapeutic Vaccine in Combination With Ipilimumab in Patients With Previously Treated Unresectable Stage III or IV Melanoma (TriMix-Ipi) | NCT01302496

Trial of RNActive®-Derived Prostate Cancer Vaccine in Metastatic Castrate-refractory Prostate Cancer | NCT01817738

RBL001/RBL002 Phase I Clinical Trial (MERIT) | NCT01684241

Trial of RNActive®-Derived Cancer Vaccine and Local Radiation in in Stage IV Non Small Cell Lung Cancer (NSCLC) | NCT01915524

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