Published in J Biol Chem on April 28, 2014
Structure and function of the feed-forward loop network motif. Proc Natl Acad Sci U S A (2003) 12.50
Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature (1996) 4.34
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics (2005) 3.92
Network motifs in integrated cellular networks of transcription-regulation and protein-protein interaction. Proc Natl Acad Sci U S A (2004) 3.60
Topological generalizations of network motifs. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 1.78
PR localization and anterior pituitary cell populations in vitro in ovariectomized wild-type and PR-knockout mice. Endocrinology (2001) 1.48
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A (2013) 1.42
Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor. Endocr Rev (1997) 1.37
Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1. Biol Reprod (2006) 1.31
Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells. J Biol Chem (2002) 1.30
Definition, conservation and epigenetics of housekeeping and tissue-enriched genes. BMC Genomics (2009) 1.30
Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5. Mol Endocrinol (2003) 1.23
Growth differentiation factor-9 promotes the growth, development, and survival of human ovarian follicles in organ culture. J Clin Endocrinol Metab (2002) 1.23
Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function. PLoS Genet (2011) 1.20
Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins. J Biol Chem (2000) 1.20
Gonadotropin-releasing hormone pulse frequency-dependent activation of extracellular signal-regulated kinase pathways in perifused LbetaT2 cells. Endocrinology (2005) 1.13
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care. Fertil Steril (2010) 1.13
Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration. Endocrinology (2003) 1.13
A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone. Proc Natl Acad Sci U S A (1995) 1.09
Thyrotropin-releasing hormone and gonadotropin-releasing hormone receptors activate phospholipase C by coupling to the guanosine triphosphate-binding proteins Gq and G11. Mol Endocrinol (1992) 1.07
Gonadotropin-releasing hormone: role of pulsatile secretion in the regulation of reproduction. N Engl J Med (1986) 1.04
Module dynamics of the GnRH signal transduction network. J Theor Biol (2002) 1.01
Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line. Endocrinology (2006) 1.01
Follistatin binds to both activin and inhibin through the common subunit. Endocrinology (1991) 1.01
Frequency-dependent regulation of follicle-stimulating hormone beta by pulsatile gonadotropin-releasing hormone is mediated by functional antagonism of bZIP transcription factors. Mol Cell Biol (2009) 1.00
Gonadotropin-releasing hormone regulates follicle-stimulating hormone-beta gene expression through an activin/follistatin autocrine or paracrine loop. Endocrinology (1996) 1.00
Negative feedback governs gonadotrope frequency-decoding of gonadotropin releasing hormone pulse-frequency. PLoS One (2009) 0.97
Follistatin gene expression in the pituitary: localization in gonadotropes and folliculostellate cells in diestrous rats. Endocrinology (1992) 0.96
Luteinizing hormone beta promoter stimulation by adenylyl cyclase and cooperation with gonadotropin-releasing hormone 1 in transgenic mice and LBetaT2 Cells. Biol Reprod (2007) 0.93
Hypothalamic dysfunction. Mol Cell Endocrinol (2001) 0.92
Gonadotropin-releasing hormone pulse sensitivity of follicle-stimulating hormone-beta gene is mediated by differential expression of positive regulatory activator protein 1 factors and corepressors SKIL and TGIF1. Mol Endocrinol (2011) 0.92
Signaling responses to pulsatile gonadotropin-releasing hormone in LbetaT2 gonadotrope cells. J Biol Chem (2010) 0.92
In vivo treatment with GDF-9 stimulates primordial and primary follicle progression and theca cell marker CYP17 in ovaries of immature rats. Endocrinology (2000) 0.92
GnRH pulse frequency-dependent stimulation of FSHβ transcription is mediated via activation of PKA and CREB. Mol Endocrinol (2013) 0.91
Transcriptional regulation of follistatin expression by GnRH in mouse gonadotroph cell lines: evidence for a role for cAMP signaling. Mol Cell Endocrinol (2007) 0.91
GnRH stimulates expression of PACAP in the pituitary gonadotropes via both the PKA and PKC signaling systems. Mol Endocrinol (2009) 0.90
Gonadotropin-releasing hormone activates a rapid Ca2+-independent phosphodiester hydrolysis of polyphosphoinositides in pituitary gonadotrophs. J Biol Chem (1986) 0.90
Rapid augmentation by progesterone of agonist-stimulated luteinizing hormone secretion by cultured pituitary cells. Endocrinology (1990) 0.89
Multifunctional cells of mouse anterior pituitary reveal a striking sexual dimorphism. J Physiol (2003) 0.87
Pulse frequency-dependent gonadotropin gene expression by adenylate cyclase-activating polypeptide 1 in perifused mouse pituitary gonadotroph LbetaT2 cells. Biol Reprod (2009) 0.86
Pituitary adenylate cyclase-activating polypeptide (PACAP) potentiates the gonadotropin-releasing activity of luteinizing hormone-releasing hormone. Endocrinology (1991) 0.85
GnRH increases c-Fos half-life contributing to higher FSHβ induction. Mol Endocrinol (2012) 0.83
Quantitative analysis of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) gene expression in calf and adult bovine ovaries. Reprod Biol Endocrinol (2011) 0.82
Modulation of gonadotropin-releasing hormone-induced extracellular signal-regulated kinase activation by dual-specificity protein phosphatase 1 in LbetaT2 gonadotropes. Endocrinology (2010) 0.82
G proteins and autocrine signaling differentially regulate gonadotropin subunit expression in pituitary gonadotrope. J Biol Chem (2012) 0.81
Mechanism of action of pituitary adenylate cyclase-activating polypeptide on human glycoprotein hormone alpha-subunit transcription in alphaT3-1 gonadotropes. Endocrinology (1998) 0.81
A composite feed-forward loop I4-FFL involving IHF and Crc stabilizes expression of the XylR regulator of Pseudomonas putida mt-2 from growth phase perturbations. Mol Biosyst (2011) 0.80
Expression of growth differentiation factor-9 messenger ribonucleic acid in ovarian and nonovarian rodent and human tissues. Endocrinology (1998) 0.80
Induction of dual-specificity phosphatase 1 (DUSP1) by pulsatile gonadotropin-releasing hormone stimulation: role for gonadotropin subunit expression in mouse pituitary LbetaT2 cells. Biol Reprod (2011) 0.80
β-catenin regulates GnRH-induced FSHβ gene expression. Mol Endocrinol (2012) 0.80
A mathematical model for the actions of activin, inhibin, and follistatin on pituitary gonadotrophs. Bull Math Biol (2008) 0.79
What is the role of PACAP in gonadotrope function? Peptides (2007) 0.79
Neuroendocrine control of FSH secretion: IV. Hypothalamic control of pituitary FSH-regulatory proteins and their relationship to changes in FSH synthesis and secretion. Biol Reprod (2012) 0.79
Possible role of PACAP and its PAC1 receptor in the differential regulation of pituitary LHbeta- and FSHbeta-subunit gene expression by pulsatile GnRH stimulation. Biol Reprod (2013) 0.79
Extra-ovarian expression and activity of growth differentiation factor 9. J Endocrinol (2009) 0.77