Published in Hypertension on August 01, 2014
The sympathetic nervous system alterations in human hypertension. Circ Res (2015) 1.28
Leptin Mediates High-Fat Diet Sensitization of Angiotensin II-Elicited Hypertension by Upregulating the Brain Renin-Angiotensin System and Inflammation. Hypertension (2016) 0.85
Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanism. Am J Physiol Heart Circ Physiol (2016) 0.80
A new look at the genetic and environmental coherence of metabolic syndrome components. Obesity (Silver Spring) (2015) 0.80
Understanding trends in blood pressure and their associations with body mass index in Chinese children, from 1985 to 2010: a cross-sectional observational study. BMJ Open (2015) 0.80
Association of obesity categories and high blood pressure in a rural adult Chinese population. J Hum Hypertens (2016) 0.78
Menopause, obesity and inflammation: interactive risk factors for Alzheimer's disease. Front Aging Neurosci (2015) 0.78
The cellular and molecular bases of leptin and ghrelin resistance in obesity. Nat Rev Endocrinol (2017) 0.77
The Renin Angiotensin Aldosterone System in Obesity and Hypertension: Roles in the Cardiorenal Metabolic Syndrome. Med Clin North Am (2017) 0.77
Cardiovascular Regulation by the Arcuate Nucleus of the Hypothalamus: Neurocircuitry and Signaling Systems. Hypertension (2016) 0.76
Reduced lipolysis response to adipose afferent reflex involved in impaired activation of adrenoceptor-cAMP-PKA-hormone sensitive lipase pathway in obesity. Sci Rep (2016) 0.76
Effects of leptin on sympathetic nerve activity in conscious mice. Physiol Rep (2015) 0.75
Community factors related to healthy eating & active living in counties with lower than expected adult obesity rates. BMC Obes (2016) 0.75
Curative effect of Tai Chi exercise in combination with auricular plaster therapy on improving obesity patient with secondary hyperlipidemia. Int J Clin Exp Med (2015) 0.75
EMP acupoint stimulation conducive to increase the effect of weight reduction through aerobic exercise. Int J Clin Exp Med (2015) 0.75
The effects of abdominal interferential current therapy on waist circumference and visceral fat distance in obese women. J Phys Ther Sci (2017) 0.75
Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition. Sci Rep (2017) 0.75
A controlled trial of renal denervation for resistant hypertension. N Engl J Med (2014) 14.22
Prevalence of resistant hypertension in the United States, 2003-2008. Hypertension (2011) 4.61
Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB. Nat Med (2011) 3.15
Modulation of blood pressure by central melanocortinergic pathways. N Engl J Med (2008) 2.86
Progression is accelerated from prehypertension to hypertension in blacks. Hypertension (2011) 2.82
Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem (2010) 2.53
Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension (2010) 2.38
Health-related quality of life after renal denervation in patients with treatment-resistant hypertension. Hypertension (2012) 2.17
Fatty kidney, hypertension, and chronic kidney disease: the Framingham Heart Study. Hypertension (2011) 2.13
Experimental hyperleptinemia in neonatal rats leads to selective leptin responsiveness, hypertension, and altered myocardial function. Hypertension (2013) 2.06
Sympathetic response to insulin is mediated by melanocortin 3/4 receptors in the hypothalamic paraventricular nucleus. Hypertension (2011) 2.06
Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults. Hypertension (2010) 2.01
Systemic and renal-specific sympathoinhibition in obesity hypertension. Hypertension (2011) 1.97
Adipose and height growth through childhood and blood pressure status in a large prospective cohort study. Hypertension (2012) 1.89
Renal sympathetic denervation in patients with treatment-resistant hypertension after witnessed intake of medication before qualifying ambulatory blood pressure. Hypertension (2013) 1.83
Blood pressure and obesity exert independent influences on pulse wave velocity in youth. Hypertension (2012) 1.70
Arterial stiffening precedes systolic hypertension in diet-induced obesity. Hypertension (2013) 1.65
Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction. Hypertension (2012) 1.63
G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension. Hypertension (2012) 1.59
Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension. Hypertension (2012) 1.54
Renal denervation attenuates the sodium retention and hypertension associated with obesity. Hypertension (1995) 1.53
Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension. Hypertension (2012) 1.52
Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. Hypertension (2013) 1.52
Intensified effect of adiposity on blood pressure in overweight and obese children. Hypertension (2011) 1.46
Interactions between leptin and the human sympathetic nervous system. Hypertension (2003) 1.44
Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the Zucker obese rat. Hypertension (2010) 1.32
Control of blood pressure, appetite, and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons. Hypertension (2011) 1.30
Efficacy of spironolactone therapy in patients with true resistant hypertension. Hypertension (2009) 1.28
Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circ Res (2011) 1.27
Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy. Hypertension (2004) 1.22
Selective leptin resistance revisited. Am J Physiol Regul Integr Comp Physiol (2013) 1.21
Adipocyte deficiency of angiotensinogen prevents obesity-induced hypertension in male mice. Hypertension (2012) 1.21
Mechanisms mediating renal sympathetic activation to leptin in obesity. Am J Physiol Regul Integr Comp Physiol (2008) 1.20
Overweight and hypertension : a 2-way street? Hypertension (2000) 1.15
Impact of body mass index and waist circumference on the long-term risk of diabetes mellitus, hypertension, and cardiac organ damage. Hypertension (2011) 1.14
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet. Hypertension (2012) 1.14
Rapid onset of renal sympathetic nerve activation in rabbits fed a high-fat diet. Hypertension (2012) 1.12
Obesity-related hypertension and the role of insulin and leptin in high-fat-fed rabbits. Hypertension (2013) 1.10
Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice. Hypertension (2011) 1.02
Sympathetic function in human carriers of melanocortin-4 receptor gene mutations. J Clin Endocrinol Metab (2010) 1.00
Body mass index and early kidney function decline in young adults: a longitudinal analysis of the CARDIA (Coronary Artery Risk Development in Young Adults) study. Am J Kidney Dis (2013) 1.00
CD36 and Na/K-ATPase-α1 form a proinflammatory signaling loop in kidney. Hypertension (2012) 0.99
A role for TRPV1 in influencing the onset of cardiovascular disease in obesity. Hypertension (2012) 0.98
Differential effects of insulin on sympathetic nerve activity in agouti obese mice. J Hypertens (2010) 0.98
Sex differences in the contributions of visceral and total body fat to blood pressure in adolescence. Hypertension (2012) 0.96
Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. Hypertension (2012) 0.95
The brain subfornical organ mediates leptin-induced increases in renal sympathetic activity but not its metabolic effects. Hypertension (2013) 0.95
Neuropeptide Y promoter polymorphism modifies effects of a weight-loss diet on 2-year changes of blood pressure: the preventing overweight using novel dietary strategies trial. Hypertension (2012) 0.94
Exposure to a high-fat diet during development alters leptin and ghrelin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits. Hypertension (2013) 0.92
Enhanced adipose afferent reflex contributes to sympathetic activation in diet-induced obesity hypertension. Hypertension (2012) 0.92
Adolescent obesity, change in weight status, and hypertension: racial/ethnic variations. Hypertension (2012) 0.91
Role of proopiomelanocortin neuron Stat3 in regulating arterial pressure and mediating the chronic effects of leptin. Hypertension (2013) 0.91
Role of KCNQ channels in skeletal muscle arteries and periadventitial vascular dysfunction. Hypertension (2012) 0.90
Cafeteria diet increases fat mass and chronically elevates lumbar sympathetic nerve activity in rats. Hypertension (2012) 0.90
Cardiovascular and sympathetic effects of disrupting tyrosine 985 of the leptin receptor. Hypertension (2011) 0.89
Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity. Hypertension (2012) 0.89
Experimental hyperleptinemia acutely increases vasoconstrictory sympathetic nerve activity in healthy humans. J Clin Endocrinol Metab (2013) 0.89
Leptin acts in the forebrain to differentially influence baroreflex control of lumbar, renal, and splanchnic sympathetic nerve activity and heart rate. Hypertension (2013) 0.87
Effects of weight loss on structural and functional alterations of subcutaneous small arteries in obese patients. Hypertension (2011) 0.86
Hemodynamic and metabolic responses to valsartan and atenolol in obese hypertensive patients. J Hypertens (2005) 0.84
Cellular and molecular mechanisms of arterial stiffness associated with obesity. Hypertension (2013) 0.83
Effects of renal sympathetic denervation on exercise blood pressure, heart rate, and capacity in patients with resistant hypertension. Hypertension (2014) 0.82
Neuroanatomical determinants of the sympathetic nerve responses evoked by leptin. Clin Auton Res (2012) 0.82
Inactivation of Bardet-Biedl syndrome genes causes kidney defects. Am J Physiol Renal Physiol (2010) 0.81
Dietary therapy for obesity: an emperor with no clothes. Hypertension (2008) 0.80
Potential clinical application of recently discovered brain mechanisms involved in hypertension. Hypertension (2013) 0.79
The influence of sex on early stage markers of kidney dysfunction in response to juvenile obesity. Hypertension (2012) 0.79
Left ventricular mass and function with reduced-fat or reduced-carbohydrate hypocaloric diets in overweight and obese subjects. Hypertension (2011) 0.79
Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes. Am J Physiol Heart Circ Physiol (2010) 0.79
Mechanisms underlying hypertension and obesity: a melanocortin linkage in the brain. Hypertension (2011) 0.78
Allele-specific expression of angiotensinogen in human subcutaneous adipose tissue. Hypertension (2013) 0.78
Relationships between selected gene polymorphisms and blood pressure sensitivity to weight loss in elderly persons with hypertension. Hypertension (2013) 0.77
Prevention of hypertension and cardiovascular diseases: a comparison of lifestyle factors in Westerners and East Asians. Hypertension (2014) 0.77
Pharmacogenetics of antihypertensive response. Hypertension (2012) 0.77
Sympathetic tone in the young: the mother weighs in. Hypertension (2009) 0.76
Interventional approaches to reduce sympathetic activity in resistant hypertension: to ablate or stimulate? Hypertension (2011) 0.76
Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity. J Hypertens (2013) 0.76
The adipose/circulating renin-angiotensin system cross-talk enters a new dimension. Hypertension (2012) 0.76
A guide to analysis of mouse energy metabolism. Nat Methods (2011) 3.82
The central melanocortin system directly controls peripheral lipid metabolism. J Clin Invest (2007) 2.97
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat Med (2010) 2.76
A knockin mouse model of the Bardet-Biedl syndrome 1 M390R mutation has cilia defects, ventriculomegaly, retinopathy, and obesity. Proc Natl Acad Sci U S A (2007) 2.36
The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance. Cell Metab (2010) 2.26
BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell (2012) 2.20
Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling. Hum Mol Genet (2009) 2.16
Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome. Hum Mol Genet (2005) 2.04
The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation. Neuron (2009) 1.97
SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab (2010) 1.64
Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways. Gastroenterology (2012) 1.58
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity. J Neurosci (2009) 1.54
Amylin acts in the central nervous system to increase sympathetic nerve activity. Endocrinology (2013) 1.47
Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications. J Hypertens (2002) 1.45
Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation. Cell Metab (2007) 1.39
The concept of selective leptin resistance: evidence from agouti yellow obese mice. Diabetes (2002) 1.37
Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes. Proc Natl Acad Sci U S A (2011) 1.32
Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling. Diabetes (2012) 1.29
Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circ Res (2011) 1.27
Glucose depletion in the airway surface liquid is essential for sterility of the airways. PLoS One (2011) 1.26
Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney. Hypertension (2008) 1.23
Mechanisms mediating renal sympathetic activation to leptin in obesity. Am J Physiol Regul Integr Comp Physiol (2008) 1.20
A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. Am J Physiol Heart Circ Physiol (2012) 1.14
Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects. Cell Metab (2013) 1.05
Role of leptin in the cardiovascular and endocrine complications of metabolic syndrome. Diabetes Obes Metab (2006) 1.04
The -20 and -217 promoter variants dominate differential angiotensinogen haplotype regulation in angiotensinogen-expressing cells. Hypertension (2007) 1.03
The brain and brown fat. Ann Med (2014) 1.02
Molecular basis of the obesity associated with Bardet-Biedl syndrome. Trends Endocrinol Metab (2011) 1.01
Metabolic rate regulation by the renin-angiotensin system: brain vs. body. Pflugers Arch (2012) 0.99
Differential effects of insulin on sympathetic nerve activity in agouti obese mice. J Hypertens (2010) 0.98
Involvement of hypothalamic AMP-activated protein kinase in leptin-induced sympathetic nerve activation. PLoS One (2013) 0.92
Loss of leptin actions in obesity: two concepts with cardiovascular implications. Clin Exp Hypertens (2005) 0.90
Cardiovascular and sympathetic effects of disrupting tyrosine 985 of the leptin receptor. Hypertension (2011) 0.89
Neuronal receptor activity-modifying protein 1 promotes energy expenditure in mice. Diabetes (2011) 0.86
The role of hypothalamic mTORC1 signaling in insulin regulation of food intake, body weight, and sympathetic nerve activity in male mice. Endocrinology (2015) 0.86
Ectopic expression of human BBS4 can rescue Bardet-Biedl syndrome phenotypes in Bbs4 null mice. PLoS One (2013) 0.84
Obesity, sympathetic overdrive, and hypertension: the leptin connection. Hypertension (2010) 0.83
Neuroanatomical determinants of the sympathetic nerve responses evoked by leptin. Clin Auton Res (2012) 0.82
Metabolic control by S6 kinases depends on dietary lipids. PLoS One (2012) 0.82
PI3K signaling: A key pathway in the control of sympathetic traffic and arterial pressure by leptin. Mol Metab (2013) 0.82
Inactivation of Bardet-Biedl syndrome genes causes kidney defects. Am J Physiol Renal Physiol (2010) 0.81
Id3, E47, and SREBP-1c: fat factors controlling adiponectin expression. Circ Res (2008) 0.81
Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes. Am J Physiol Heart Circ Physiol (2010) 0.79
K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis. Cell Metab (2013) 0.78
Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity. J Hypertens (2013) 0.76
Sympathetic inhibition after bariatric surgery. Hypertension (2014) 0.76
Sympathetic tone in the young: the mother weighs in. Hypertension (2009) 0.76
The adipose/circulating renin-angiotensin system cross-talk enters a new dimension. Hypertension (2012) 0.76
Editorial focus: A fat contribution to RAS activation and blood pressure control: evidence from angiotensinogen conditional null mice. Focus on: "Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice.". Am J Physiol Regul Integr Comp Physiol (2011) 0.75
Does genetic variation in the leptin receptor influence the sympathetic tone in obesity? Hypertens Res (2008) 0.75
Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism. J Clin Invest (2017) 0.75