Published in Cancer Res on May 21, 2014
Turning hepatic cancer stem cells inside out--a deeper understanding through multiple perspectives. Mol Cells (2015) 0.86
MicroRNA-153 promotes Wnt/β-catenin activation in hepatocellular carcinoma through suppression of WWOX. Oncotarget (2015) 0.85
Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells. Mol Cell Proteomics (2015) 0.84
Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling. Oncotarget (2016) 0.80
Wnt5A expression is associated with the tumor metastasis and clinical survival in cervical cancer. Int J Clin Exp Pathol (2014) 0.77
Hepatoblastoma: A Need for Cell Lines and Tissue Banks to Develop Targeted Drug Therapies. Front Pediatr (2016) 0.76
Hepatoblastoma modeling in mice places Nrf2 within a cancer field established by mutant β-catenin. JCI Insight (2016) 0.75
Environmental Ligands of the Aryl Hydrocarbon Receptor and Their Effects in Models of Adult Liver Progenitor Cells. Stem Cells Int (2016) 0.75
Molecular Pathogenesis of Hepatocellular Carcinoma. Liver Cancer (2016) 0.75
Targeting β-catenin in hepatocellular cancers induced by co-expression of mutant β-catenin and K-Ras in mice. Hepatology (2016) 0.75
Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation. Neoplasia (2016) 0.75
Liver Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells. Cancers (Basel) (2017) 0.75
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
Hepatocellular carcinoma. N Engl J Med (2011) 19.40
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell (2006) 12.72
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J (1999) 10.82
Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer (2010) 8.55
Bidirectional transport of amino acids regulates mTOR and autophagy. Cell (2009) 7.88
Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol Cancer Ther (2006) 7.73
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet (2010) 6.81
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med (2006) 6.31
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci U S A (1998) 4.99
The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene (2010) 4.00
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC. Gastroenterology (2006) 3.95
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest (2004) 3.92
Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. Dev Biol (2007) 2.48
Flow-cytometric separation and enrichment of hepatic progenitor cells in the developing mouse liver. Hepatology (2000) 2.43
Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J Cell Sci (2003) 2.38
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism. Oncogene (2002) 2.23
Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res (1999) 2.18
beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance. Cancer (2001) 2.17
Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res (2004) 2.01
Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells. Cancer Res (2008) 1.98
Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver. J Cell Biol (2002) 1.88
Liver cancer stem cells. J Clin Oncol (2008) 1.82
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin. Hepatology (2010) 1.71
Amplification and overexpression of the cyclin D1 gene in aggressive human hepatocellular carcinoma. Cancer Res (1994) 1.63
Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin. Cancer Res (2001) 1.63
Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res (2002) 1.62
Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver. Gastroenterology (2005) 1.58
Role of Wnt/β-catenin signaling in liver metabolism and cancer. Int J Biochem Cell Biol (2009) 1.55
The biliary tree--a reservoir of multipotent stem cells. Nat Rev Gastroenterol Hepatol (2012) 1.50
Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice. Mol Cell Biol (2005) 1.40
Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology (2008) 1.31
Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma. J Cell Biochem (2008) 1.19
Expression of c-Myc, c-Fos, and c-jun in hepatocellular carcinoma. Cancer (2001) 1.16
Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of beta-catenin in the liver. Hepatology (2004) 1.12
CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma. J Clin Invest (2012) 1.09
Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors. Cancer Res (2011) 1.09
Up-regulated expression of stathmin may be associated with hepatocarcinogenesis. Oncol Rep (2010) 0.98
Overexpression of protein kinase C alpha mRNA in human hepatocellular carcinoma: a potential marker of disease prognosis. Clin Chim Acta (2007) 0.98
pp60c-src activation in hepatocellular carcinoma of humans and LEC rats. Hepatology (1998) 0.98
The emerging family of hepatoblastoma tumours: from ontogenesis to oncogenesis. Eur J Cancer (2005) 0.96
Stem-like cells in human hepatoblastoma. J Histochem Cytochem (2004) 0.85
Human hepatic progenitor cells express hematopoietic cell markers CD45 and CD109. Int J Med Sci (2013) 0.84
CITED1 expression in liver development and hepatoblastoma. Neoplasia (2012) 0.84
Glutamine metabolism and signaling in the liver. Front Biosci (2007) 0.83
Concomitant lung metastasis in patients with advanced hepatocellular carcinoma. World J Gastroenterol (2012) 0.81
Clonal colony formation of hepatic stem/progenitor cells enhanced by embryonic fibroblast conditioning medium. Transplant Proc (2000) 0.78
A study of therapy for pediatric hepatoblastoma: prevention and treatment of pulmonary metastasis. Eur J Pediatr Surg (1999) 0.76