Published in Cell Death Dis on May 22, 2014
Long non-coding RNA CCAT1 promotes gallbladder cancer development via negative modulation of miRNA-218-5p. Cell Death Dis (2015) 1.67
Long Noncoding RNAs in Cancer Pathways. Cancer Cell (2016) 1.63
Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2. Mol Cancer (2017) 1.43
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets. Mol Cell Ther (2015) 1.32
Functions of lncRNA HOTAIR in lung cancer. J Hematol Oncol (2014) 1.23
Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2. Mol Cancer (2015) 1.17
Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16. Mol Cancer (2015) 1.08
Long noncoding RNAs in cancer: from function to translation. Trends Cancer (2015) 1.06
Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57. Cell Death Dis (2016) 1.06
Low expression of long noncoding RNA PANDAR predicts a poor prognosis of non-small cell lung cancer and affects cell apoptosis by regulating Bcl-2. Cell Death Dis (2015) 1.04
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA. Sci Rep (2015) 1.04
The long non-coding RNA TUG1 indicates a poor prognosis for colorectal cancer and promotes metastasis by affecting epithelial-mesenchymal transition. J Transl Med (2016) 1.03
The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144. Oncotarget (2015) 0.95
LncRNA TUG1 acts as a tumor suppressor in human glioma by promoting cell apoptosis. Exp Biol Med (Maywood) (2016) 0.92
Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. Cell Death Dis (2016) 0.92
Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells. Oncotarget (2015) 0.90
Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer. Int J Clin Exp Pathol (2015) 0.89
Long non-coding RNA taurine upregulated 1 enhances tumor-induced angiogenesis through inhibiting microRNA-299 in human glioblastoma. Oncogene (2016) 0.88
Long Noncoding RNAs as New Architects in Cancer Epigenetics, Prognostic Biomarkers, and Potential Therapeutic Targets. Biomed Res Int (2015) 0.88
Co-LncRNA: investigating the lncRNA combinatorial effects in GO annotations and KEGG pathways based on human RNA-Seq data. Database (Oxford) (2015) 0.87
Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2. BMC Cancer (2016) 0.87
Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin. Mol Med Rep (2015) 0.86
Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway. Oncotarget (2016) 0.86
E2F1-induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs. Oncotarget (2016) 0.85
De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics. Mol Ther Nucleic Acids (2014) 0.83
Downregulation of the long noncoding RNA TUG1 inhibits the proliferation, migration, invasion and promotes apoptosis of renal cell carcinoma. J Mol Histol (2016) 0.83
Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment. Nat Commun (2016) 0.82
Current status of long non-coding RNAs in human cancer with specific focus on colorectal cancer. Int J Mol Sci (2014) 0.82
Comprehensive comparative homeobox gene annotation in human and mouse. Database (Oxford) (2015) 0.82
Expression and clinicopathological significance of the lncRNA HOXA11-AS in colorectal cancer. Oncol Lett (2016) 0.81
Targeting long non-coding RNA-TUG1 inhibits tumor growth and angiogenesis in hepatoblastoma. Cell Death Dis (2016) 0.81
LncRNA TUG1 is upregulated and promotes cell proliferation in osteosarcoma. Open Med (Wars) (2016) 0.81
CCAT1: an oncogenic long noncoding RNA in human cancers. J Cancer Res Clin Oncol (2016) 0.79
Functions and mechanisms of long noncoding RNAs in lung cancer. Onco Targets Ther (2016) 0.79
Characters, functions and clinical perspectives of long non-coding RNAs. Mol Genet Genomics (2016) 0.79
Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. Cold Spring Harb Perspect Med (2017) 0.78
Long Non-coding RNAs and Their Roles in Non-small-cell Lung Cancer. Genomics Proteomics Bioinformatics (2016) 0.78
Expression and clinical significance of long non-coding RNA HNF1A-AS1 in human gastric cancer. World J Surg Oncol (2015) 0.78
The function of homeobox genes and lncRNAs in cancer. Oncol Lett (2016) 0.78
The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain. Oncogene (2015) 0.78
LncRNA DQ786243 contributes to proliferation and metastasis of colorectal cancer both in vitro and in vivo. Biosci Rep (2016) 0.78
Cancer subtypes classification using long non-coding RNA. Oncotarget (2016) 0.78
The prognostic significance of long noncoding RNAs in non-small cell lung cancer: a meta-analysis. Oncotarget (2016) 0.78
Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proc Natl Acad Sci U S A (2017) 0.78
Long non-coding RNA CCAT2 promotes gastric cancer proliferation and invasion by regulating the E-cadherin and LATS2. Am J Cancer Res (2016) 0.77
Census and evaluation of p53 target genes. Oncogene (2017) 0.77
Role of Exosomal Noncoding RNAs in Lung Carcinogenesis. Biomed Res Int (2015) 0.77
Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis. Oncotarget (2017) 0.77
LncRNA BCAR4 wires up signaling transduction in breast cancer. RNA Biol (2015) 0.77
Long Non-Coding RNA Expression during Aging in the Human Subependymal Zone. Front Neurol (2015) 0.77
Screening of long non-coding RNA and TUG1 inhibits proliferation with TGF-β induction in patients with COPD. Int J Chron Obstruct Pulmon Dis (2016) 0.76
The Widening Sphere of Influence of HOXB7 in Solid Tumors. Cancer Res (2016) 0.76
LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancer. Sci Rep (2016) 0.75
The prognostic value of long non coding RNAs in non small cell lung cancer: A meta-analysis. Oncotarget (2016) 0.75
Identification of lncRNA functions in lung cancer based on associated protein-protein interaction modules. Sci Rep (2016) 0.75
LincRNAFEZF1-AS1 represses p21 expression to promote gastric cancer proliferation through LSD1-Mediated H3K4me2 demethylation. Mol Cancer (2017) 0.75
LncRNA Taurine-Upregulated Gene 1 Promotes Cell Proliferation by Inhibiting MicroRNA-9 in MCF-7 Cells. J Breast Cancer (2016) 0.75
MicroRNA-210 Plays a Critical Role in the Angiogenic Effect of Isoprenaline on Human Umbilical Vein Endothelial Cells via Regulation of Noncoding RNAs. Chin Med J (Engl) (2016) 0.75
Altered long non-coding RNAs predict worse outcome in osteosarcoma patients: evidence from a meta-analysis. Oncotarget (2017) 0.75
Up-regulation of Long Non-coding RNA TUG1 in Hibernating Thirteen-lined Ground Squirrels. Genomics Proteomics Bioinformatics (2016) 0.75
Long non-coding RNA LOC283070 mediates the transition of LNCaP cells into androgen-independent cells possibly via CAMK1D. Am J Transl Res (2016) 0.75
Tanshinol suppresses endothelial cells apoptosis in mice with atherosclerosis via lncRNA TUG1 up-regulating the expression of miR-26a. Am J Transl Res (2016) 0.75
A novel long noncoding RNA IRAIN regulates cell proliferation in non small cell lung cancer. Int J Clin Exp Pathol (2015) 0.75
Upregulation of long noncoding RNA TUG1 promotes cervical cancer cell proliferation and migration. Cancer Med (2017) 0.75
LncRNAs and Esophageal Squamous Cell Carcinoma - Implications for Pathogenesis and Drug Development. J Cancer (2016) 0.75
The expanding regulatory universe of p53 in gastrointestinal cancer. F1000Res (2016) 0.75
An Insight into the Increasing Role of LncRNAs in the Pathogenesis of Gliomas. Front Mol Neurosci (2017) 0.75
LncRNAs: From Basic Research to Medical Application. Int J Biol Sci (2017) 0.75
Long non-coding RNA GAS5 inhibits cell proliferation, induces G0/G1 arrest and apoptosis, and functions as a prognostic marker in colorectal cancer. Oncol Lett (2017) 0.75
Down-regulation of LncRNA TUG1 enhances radiosensitivity in bladder cancer via suppressing HMGB1 expression. Radiat Oncol (2017) 0.75
Long intergenic non-coding RNA 00152 promotes lung adenocarcinoma proliferation via interacting with EZH2 and repressing IL24 expression. Mol Cancer (2017) 0.75
Prognostic value of long non-coding RNA TUG1 in various tumors. Oncotarget (2017) 0.75
BANCR: a cancer-related long non-coding RNA. Am J Cancer Res (2017) 0.75
Overexpression of lncRNA IGFBP4-1 reprograms energy metabolism to promote lung cancer progression. Mol Cancer (2017) 0.75
Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression. Cell Death Dis (2017) 0.75
Long non-coding RNA TUG1 promotes cervical cancer progression by regulating the miR-138-5p-SIRT1 axis. Oncotarget (2017) 0.75
Long non-coding RNAs as an Epigenetic Regulator in Human Cancers. Cancer Sci (2017) 0.75
The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma. Oncotarget (2017) 0.75
Roles of Long Noncoding RNAs in Recurrence and Metastasis of Radiotherapy-Resistant Cancer Stem Cells. Int J Mol Sci (2017) 0.75
PART1 expression is associated with poor prognosis and tumor recurrence in stage I-III non-small cell lung cancer. J Cancer (2017) 0.75
Long Noncoding RNAs and RNA-Binding Proteins in Oxidative Stress, Cellular Senescence, and Age-Related Diseases. Oxid Med Cell Longev (2017) 0.75
Specific long non-coding RNAs response to occupational PAHs exposure in coke oven workers. Toxicol Rep (2016) 0.75
Long non-coding RNA TUG1 as a potential prognostic biomarker in human cancers: a meta-analysis. Oncotarget (2017) 0.75
Long non-coding RNA TUG1 promotes progression of oral squamous cell carcinoma through upregulating FMNL2 by sponging miR-219. Am J Cancer Res (2017) 0.75
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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
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The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol (2007) 18.32
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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature (2011) 11.59
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A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene (2003) 7.90
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Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol (2011) 6.54
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Modulating Hox gene functions during animal body patterning. Nat Rev Genet (2005) 5.10
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene (2010) 4.81
Genomic analysis of mouse retinal development. PLoS Biol (2004) 4.66
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The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Curr Biol (2005) 3.15
HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition. Cancer Res (2006) 2.66
The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. Cancer Res (2011) 2.52
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction. J Hum Genet (2006) 2.41
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A noncoding RNA is a potential marker of cell fate during mammary gland development. Proc Natl Acad Sci U S A (2006) 1.94
Intronic RNAs mediate EZH2 regulation of epigenetic targets. Nat Struct Mol Biol (2012) 1.56
Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis. Asian Pac J Cancer Prev (2013) 1.55
Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis. PLoS One (2009) 1.54
Analysis of long non-coding RNA expression profiles in gastric cancer. World J Gastroenterol (2013) 1.50
Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder. J Surg Oncol (2012) 1.48
HOXB7 as a prognostic factor and mediator of colorectal cancer progression. Clin Cancer Res (2011) 1.31
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HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer (2012) 1.17
Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus. Proc Natl Acad Sci U S A (2012) 0.99
HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients. Leukemia (2010) 0.95
Role of HOXB7 in regulation of progression and metastasis of human lung adenocarcinoma. Mol Carcinog (2012) 0.91