CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria.

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Published in PLoS Pathog on May 22, 2014

Authors

Lei Shong Lau1, Daniel Fernandez-Ruiz1, Vanessa Mollard2, Angelika Sturm2, Michelle A Neller3, Anton Cozijnsen2, Julia L Gregory1, Gayle M Davey1, Claerwen M Jones1, Yi-Hsuan Lin1, Ashraful Haque3, Christian R Engwerda3, Catherine Q Nie4, Diana S Hansen5, Kenneth M Murphy6, Anthony T Papenfuss5, John J Miles7, Scott R Burrows3, Tania de Koning-Ward8, Geoffrey I McFadden2, Francis R Carbone1, Brendan S Crabb9, William R Heath10

Author Affiliations

1: Department of Microbiology and Immunology, The Peter Doherty Institute, University of Melbourne, Parkville, Victoria, Australia.
2: The School of Botany, University of Melbourne, Parkville, Victoria, Australia.
3: The QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
4: The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Macfarlane Burnet Institute for Medical Research & Public Health, Melbourne, Victoria, Australia.
5: The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
6: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America.
7: The QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Medicine, The University of Queensland, Brisbane, Queensland, Australia; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, Wales, United Kingdom.
8: School of Medicine, Deakin University, Waurn Ponds, Victoria, Australia.
9: Department of Microbiology and Immunology, The Peter Doherty Institute, University of Melbourne, Parkville, Victoria, Australia; Macfarlane Burnet Institute for Medical Research & Public Health, Melbourne, Victoria, Australia; Monash University, Clayton, Victoria, Australia.
10: Department of Microbiology and Immunology, The Peter Doherty Institute, University of Melbourne, Parkville, Victoria, Australia; The ARC Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Parkville, Australia.

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