Published in J Exp Med on May 26, 2014
Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A. Immunity (2015) 1.46
Cutting edge: T follicular helper cell differentiation is defective in the absence of Bcl6 BTB repressor domain function. J Immunol (2015) 0.87
Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation. J Exp Med (2017) 0.75
Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling. Front Immunol (2015) 0.75
Regulators of Tfh Cell Differentiation. Front Immunol (2016) 0.75
Follicular helper CD4 T cells (TFH). Annu Rev Immunol (2011) 12.50
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity (2008) 9.61
Bcl6 mediates the development of T follicular helper cells. Science (2009) 8.50
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity (2009) 7.69
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood (1998) 6.81
Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science (1997) 6.58
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature (2005) 6.31
Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science (2000) 5.78
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity (2011) 5.59
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet (1997) 5.55
A validated regulatory network for Th17 cell specification. Cell (2012) 4.82
The AP-1 transcription factor Batf controls T(H)17 differentiation. Nature (2009) 3.75
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity (2011) 3.58
The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat Immunol (2009) 3.44
Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity (2011) 3.24
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell (2013) 3.22
The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat Immunol (2011) 3.21
Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes Dev (1999) 3.11
SAP controls T cell responses to virus and terminal differentiation of TH2 cells. Nat Immunol (2001) 2.95
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150). J Immunol (2010) 2.85
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. Immunity (2010) 2.79
Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. Nat Immunol (2002) 2.46
Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. Genes Dev (2010) 2.31
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science (2012) 2.30
Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature (2012) 2.25
Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma. Blood (2002) 2.13
How T cells earn the follicular rite of passage. Immunity (2011) 2.03
BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature (2012) 2.00
Germinal center B and follicular helper T cells: siblings, cousins or just good friends? Nat Immunol (2011) 1.95
Batf coordinates multiple aspects of B and T cell function required for normal antibody responses. J Exp Med (2010) 1.92
Structural regulation of cullin-RING ubiquitin ligase complexes. Curr Opin Struct Biol (2011) 1.89
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity (2011) 1.83
Roles of BCL6 in normal and transformed germinal center B cells. Immunol Rev (2012) 1.78
BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms. Blood (2007) 1.72
Inhibition of Th2 differentiation and GATA-3 expression by BCL-6. J Immunol (2003) 1.63
Illustration of SSMD, z score, SSMD*, z* score, and t statistic for hit selection in RNAi high-throughput screens. J Biomol Screen (2011) 1.38
Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase. Structure (2012) 1.37
Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression. Nat Immunol (2010) 1.33
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms. Nat Immunol (2013) 1.30
Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas. Proc Natl Acad Sci U S A (2002) 1.30
Transcriptional regulation of follicular T-helper (Tfh) cells. Immunol Rev (2013) 1.28
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis. Cell Metab (2012) 1.24
The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer. Mol Biol Cell (2006) 1.22
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. Immunity (2013) 1.21
Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation. Immunity (2013) 1.19
Insights into the role of Bcl6 in follicular Th cells using a new conditional mutant mouse model. J Immunol (2013) 1.14
Transcriptional repressor BCL6 controls Th17 responses by controlling gene expression in both T cells and macrophages. J Immunol (2010) 1.12
Constitutive turnover of cyclin E by Cul3 maintains quiescence. Mol Cell Biol (2007) 1.10
BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature (2012) 1.07
BCL-6 protein is expressed in precursor T-cell lymphoblastic lymphoma and in prenatal and postnatal thymus. Blood (2001) 1.05
Insights into the role of Bcl6 in follicular Th cells using a new conditional mutant mouse model. J Immunol (2013) 1.14
STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells. J Immunol (2016) 0.82
Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production. J Immunol (2017) 0.75