N-glycosylation of asparagine 8 regulates surface expression of major histocompatibility complex class I chain-related protein A (MICA) alleles dependent on threonine 24.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 4106324)

Published in J Biol Chem on May 28, 2014

Authors

Maiken Mellergaard1, Sarah Line Skovbakke1, Christine L Schneider2, Felicia Lauridsen1, Lars Andresen1, Helle Jensen1, Søren Skov3

Author Affiliations

1: From the Laboratory of Immunology, Section for Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark and.
2: the Department of Biology, Carroll University, Waukesha, Wisconsin 53186.
3: From the Laboratory of Immunology, Section for Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870 Frederiksberg, Denmark and sosk@sund.ku.dk.

Articles cited by this

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity (2001) 5.42

NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity (2008) 5.35

A second lineage of mammalian major histocompatibility complex class I genes. Proc Natl Acad Sci U S A (1994) 3.33

Glycoprotein glycosylation and cancer progression. Biochim Biophys Acta (1999) 3.17

Effect of NKG2D ligand expression on host immune responses. Immunol Rev (2010) 3.08

Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol (2013) 2.98

NKG2D blockade prevents autoimmune diabetes in NOD mice. Immunity (2004) 2.80

Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II. J Biol Chem (1982) 2.69

Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc Natl Acad Sci U S A (2003) 2.64

Characterization of the structural determinants required for the high affinity interaction of asparagine-linked oligosaccharides with immobilized Phaseolus vulgaris leukoagglutinating and erythroagglutinating lectins. J Biol Chem (1982) 2.43

Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA. Nat Immunol (2001) 2.43

Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics (2001) 2.43

Beta 1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia. Cancer Res (1991) 2.36

N-Glycans in cancer progression. Glycobiology (2008) 2.35

Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands. Nature (2007) 2.26

Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity. J Exp Med (2003) 2.20

Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behçet disease. Proc Natl Acad Sci U S A (1997) 2.10

Toll-like receptors and dendritic cells: for whom the bug tolls. Semin Immunol (2004) 2.06

Molecular characteristics of immunogenic cancer cell death. Cell Death Differ (2007) 1.92

Immunobiology of human NKG2D and its ligands. Curr Top Microbiol Immunol (2006) 1.91

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity. Proc Natl Acad Sci U S A (2008) 1.80

Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B. Cancer Res (2005) 1.73

Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I. J Biol Chem (1990) 1.72

Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours. Immunol Cell Biol (2005) 1.71

Tumor-associated MICA is shed by ADAM proteases. Cancer Res (2008) 1.64

Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142. Biochem Biophys Res Commun (2006) 1.62

Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein. Eur J Immunol (2003) 1.46

MICA, a new polymorphic HLA-related antigen, is expressed mainly by keratinocytes, endothelial cells, and monocytes. Immunogenetics (1998) 1.43

ULBP6/RAET1L is an additional human NKG2D ligand. Eur J Immunol (2009) 1.38

Fas-ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity. Nat Immunol (2006) 1.38

MICA and MICB genes: can the enigma of their polymorphism be resolved? Trends Immunol (2001) 1.31

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells. Antioxid Redox Signal (2007) 1.26

Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein. J Immunol (2003) 1.21

Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B. J Virol (2008) 1.21

Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand. Immunity (1999) 1.19

Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity. J Immunol (2008) 1.17

The NKG2D receptor: sensing stressed cells. Trends Mol Med (2008) 1.17

Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x. J Clin Invest (2008) 1.09

NKG2D ligand MICA is retained in the cis-Golgi apparatus by human cytomegalovirus protein UL142. J Virol (2009) 1.09

A basolateral sorting motif in the MICA cytoplasmic tail. Proc Natl Acad Sci U S A (2002) 1.08

Altered T cell surface glycosylation in HIV-1 infection results in increased susceptibility to galectin-1-induced cell death. Glycobiology (2003) 1.05

The role of N-linked oligosaccharides in glycoprotein function. Trends Biotechnol (1991) 1.04

Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system. Cytokine Growth Factor Rev (2007) 0.99

Analysis of the human cancer glycome identifies a novel group of tumor-associated N-acetylglucosamine glycan antigens. Cancer Res (2009) 0.97

MICA sequences 2000. Immunogenetics (2001) 0.95

Molecular regulation of MHC class I chain-related protein A expression after HDAC-inhibitor treatment of Jurkat T cells. J Immunol (2007) 0.93

A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes. J Virol (2001) 0.92

The human herpesvirus-7 (HHV-7) U21 immunoevasin subverts NK-mediated cytoxicity through modulation of MICA and MICB. PLoS Pathog (2011) 0.91

The role of O-linked and N-linked oligosaccharides on the structure-function of glycoprotein hormones: development of agonists and antagonists. Biochim Biophys Acta (2006) 0.89

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase. J Immunol (2010) 0.88

Up-regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin. J Leukoc Biol (2003) 0.85

Human herpesvirus 7 u21 downregulates classical and nonclassical class I major histocompatibility complex molecules from the cell surface. J Virol (2010) 0.85

Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells. J Immunol (2009) 0.84

Death, danger, and immunity: an infernal trio. Immunol Rev (2007) 0.83

2-deoxy D-glucose prevents cell surface expression of NKG2D ligands through inhibition of N-linked glycosylation. J Immunol (2012) 0.82

Insight into the mechanism of human herpesvirus 7 U21-mediated diversion of class I MHC molecules to lysosomes. J Biol Chem (2010) 0.82

Skin diseases associated with human herpesvirus 6, 7, and 8 infection. J Investig Dermatol Symp Proc (2001) 0.81