PubRank

Wim Timens

Author PubWeight™ 117.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Management of lung nodules detected by volume CT scanning. N Engl J Med 2009 6.79
2 Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2010 6.39
3 Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet 2012 5.28
4 Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov 2011 4.80
5 The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2009 2.23
6 Clinical control of asthma associates with measures of airway inflammation. Thorax 2012 2.15
7 Lung eQTLs to help reveal the molecular underpinnings of asthma. PLoS Genet 2012 2.09
8 Cigarette smoke-induced emphysema: A role for the B cell? Am J Respir Crit Care Med 2006 2.05
9 A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. Am J Respir Crit Care Med 2013 1.73
10 Clinical and inflammatory determinants of bronchial hyperresponsiveness in COPD. Eur Respir J 2012 1.71
11 Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med 2009 1.70
12 Remodeling in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006 1.51
13 Molecular signature of smoking in human lung tissues. Cancer Res 2012 1.50
14 CD8⁺ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung. J Clin Invest 2011 1.40
15 ATP-binding cassette (ABC) transporters in normal and pathological lung. Respir Res 2005 1.37
16 Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. Am J Respir Crit Care Med 2009 1.35
17 Thymic epithelial tumours: a population-based study of the incidence, diagnostic procedures and therapy. Eur J Cancer 2008 1.33
18 Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors. Clin Cancer Res 2003 1.29
19 More alternative activation of macrophages in lungs of asthmatic patients. J Allergy Clin Immunol 2010 1.28
20 Acute effects of cigarette smoking on inflammation in healthy intermittent smokers. Respir Res 2005 1.25
21 Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung. Virchows Arch 2009 1.24
22 Guideline on the requirements of external quality assessment programs in molecular pathology. Virchows Arch 2012 1.24
23 Are there reasons why adult asthma is more common in females? Curr Allergy Asthma Rep 2007 1.21
24 Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease. PLoS One 2011 1.16
25 Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study. Respir Res 2007 1.13
26 Short-term smoke exposure attenuates ovalbumin-induced airway inflammation in allergic mice. Am J Respir Cell Mol Biol 2004 1.12
27 Small cell carcinoma of the lung and large cell neuroendocrine carcinoma interobserver variability. Histopathology 2010 1.11
28 Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis. Lung Cancer 2009 1.07
29 Airway epithelial changes in smokers but not in ex-smokers with asthma. Am J Respir Crit Care Med 2009 1.07
30 Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers. Respir Res 2005 1.04
31 Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD. Respir Res 2011 1.04
32 Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD. Respir Res 2008 1.03
33 Different modulation of decorin production by lung fibroblasts from patients with mild and severe emphysema. COPD 2005 1.02
34 Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls. PLoS One 2013 1.02
35 Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients. Virchows Arch 2006 1.01
36 Airways inflammation and treatment during acute exacerbations of COPD. Int J Chron Obstruct Pulmon Dis 2008 1.00
37 PET for the evaluation of pleural thickening observed on CT. J Nucl Med 2004 0.99
38 Sputum inflammation predicts exacerbations after cessation of inhaled corticosteroids in COPD. Respir Med 2011 0.98
39 Eosinophilic inflammation in subjects with mild-to-moderate asthma with and without obesity: disparity between sputum and biopsies. Am J Respir Crit Care Med 2014 0.98
40 Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. PLoS Genet 2013 0.97
41 Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation? PLoS One 2013 0.97
42 Different proliferative capacity of lung fibroblasts obtained from control subjects and patients with emphysema. Exp Lung Res 2003 0.96
43 Current smoking-specific gene expression signature in normal bronchial epithelium is enhanced in squamous cell lung cancer. J Pathol 2009 0.96
44 Interleukin-17 induces hyperresponsive interleukin-8 and interleukin-6 production to tumor necrosis factor-alpha in structural lung cells. Am J Respir Cell Mol Biol 2005 0.95
45 Reticular basement membrane in asthma and COPD: similar thickness, yet different composition. Int J Chron Obstruct Pulmon Dis 2009 0.94
46 Microarray amplification bias: loss of 30% differentially expressed genes due to long probe - poly(A)-tail distances. BMC Genomics 2007 0.94
47 Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study. BMJ Open 2013 0.92
48 Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. J Pathol 2004 0.92
49 Abnormalities in airway epithelial junction formation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2014 0.91
50 Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity. Thorax 2013 0.91
51 Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease. PLoS One 2012 0.91
52 Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease. PLoS One 2012 0.90
53 Persisting remodeling and less airway wall eosinophil activation in complete remission of asthma. Am J Respir Crit Care Med 2010 0.89
54 Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice. Respir Res 2007 0.89
55 Repeated sputum inductions induce a transient neutrophilic and eosinophilic response. Chest 2006 0.89
56 Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells? Respir Res 2008 0.89
57 Localization and enhanced mRNA expression of the orphan chemokine receptor L-CCR in the lung in a murine model of ovalbumin-induced airway inflammation. J Histochem Cytochem 2004 0.89
58 Airway remodeling and long-term decline in lung function in asthma. Curr Opin Pulm Med 2003 0.88
59 Small airways dysfunction and neutrophilic inflammation in bronchial biopsies and BAL in COPD. Chest 2007 0.87
60 Integrity of airway epithelium is essential against obliterative airway disease in transplanted rat tracheas. J Heart Lung Transplant 2005 0.86
61 Association of mast cells with lung function in chronic obstructive pulmonary disease. Respir Res 2008 0.86
62 A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke. Am J Physiol Cell Physiol 2014 0.86
63 Increased levels of (class switched) memory B cells in peripheral blood of current smokers. Respir Res 2009 0.85
64 Common and rare EGFR and KRAS mutations in a Dutch non-small-cell lung cancer population and their clinical outcome. PLoS One 2013 0.85
65 High cessation rates of cigarette smoking in subjects with and without COPD. Chest 2005 0.85
66 Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD. Respir Res 2010 0.85
67 Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells. J Biochem Mol Toxicol 2007 0.84
68 Glycogen synthase kinase-3 (GSK-3) regulates TGF-β₁-induced differentiation of pulmonary fibroblasts. Br J Pharmacol 2013 0.84
69 Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study. Respir Res 2013 0.83
70 TGF-β1 polymorphisms and asthma severity, airway inflammation, and remodeling. J Allergy Clin Immunol 2012 0.83
71 Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial. PLoS One 2013 0.82
72 Authors’ response to Persson C: primary lysis/necrosis of eosinophils and clinical control of asthma. Thorax 2013 0.82
73 Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells. Int J Chron Obstruct Pulmon Dis 2008 0.82
74 Adenosine receptors in COPD and asymptomatic smokers: effects of smoking cessation. Virchows Arch 2009 0.82
75 Nitrogen dioxide exposure attenuates cigarette smoke-induced cytokine production in mice. Inhal Toxicol 2008 0.82
76 Removal of a giant intrathoracic cyst from the anterior mediastinum. J Cardiothorac Surg 2014 0.81
77 The effect of bacillus Calmette-Guérin immunization depends on the genetic predisposition to Th2-type responsiveness. Am J Respir Cell Mol Biol 2002 0.81
78 Pulmonary microcystic fibromyxoma: Report of 3 cases. Am J Surg Pathol 2006 0.81
79 Bone histomorphometry in children with newly diagnosed acute lymphoblastic leukemia. Pediatr Res 2003 0.81
80 Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice. BMC Pulm Med 2010 0.81
81 A chronic obstructive pulmonary disease related signature in squamous cell lung cancer. Lung Cancer 2010 0.81
82 Expression and prognostic implications of apoptosis-related proteins in locally unresectable non-small cell lung cancers. Lung Cancer 2006 0.80
83 Effects of IL-4 and IL-13 on adenosine receptor expression and responsiveness of the human mast cell line 1. Int Immunopharmacol 2008 0.80
84 Differential effects of fluticasone on extracellular matrix production by airway and parenchymal fibroblasts in severe COPD. Am J Physiol Lung Cell Mol Physiol 2013 0.80
85 Differential switching to IgG and IgA in active smoking COPD patients and healthy controls. Eur Respir J 2012 0.79
86 Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD. PLoS One 2012 0.79
87 Multidrug resistance-associated protein 1 and lung function decline with or without long-term corticosteroids treatment in COPD. Eur J Pharmacol 2012 0.79
88 Expression of vascular remodelling markers in relation to bradykinin receptors in asthma and COPD. Thorax 2013 0.78
89 Smoking and nonsmoking asthma: differences in clinical outcome and pathogenesis. Expert Rev Respir Med 2011 0.78
90 Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization. J Cell Mol Med 2014 0.77
91 Interaction between Epac1 and miRNA-7 in airway smooth muscle cells. Naunyn Schmiedebergs Arch Pharmacol 2014 0.77
92 Can AMP induce sputum eosinophils, even in subjects with complete asthma remission? Respir Res 2010 0.77
93 Phosphodiesterase 4 inhibitors: antiinflammatory therapy for chronic obstructive pulmonary disease at last? Am J Respir Crit Care Med 2003 0.77
94 Proteomic analysis of human epithelial lining fluid by microfluidics-based nanoLC-MS/MS: a feasibility study. Electrophoresis 2013 0.77
95 Idiopathic pulmonary arterial hypertension in Dutch Caucasian patients is not associated with human herpes virus-8 infection. Respir Med 2006 0.76
96 Genome-wide genetic ancestry measurements to predict lung function in European populations. Eur Respir J 2013 0.76
97 Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One 2015 0.75
98 Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer. Genet Epidemiol 2015 0.75
99 Successful lung transplantation in the presence of pre-existing donor-specific cytotoxic HLA Class II antibodies. J Heart Lung Transplant 2012 0.75
100 Clinical-pathologic conference in surgery for congenital and acquired cardiovascular disease: unilateral pulmonary vein stenosis with a contralateral pulmonary varix. J Thorac Cardiovasc Surg 2007 0.75
101 Feasibility of sputum induction in lung transplant recipients. Clin Transplant 2004 0.75
102 [New 'targeted therapy' for lung cancer]. Ned Tijdschr Geneeskd 2011 0.75
103 The role of apoptosis-related genes in non-small-cell lung cancer. Clin Lung Cancer 2002 0.75
104 Quantitative Epstein-Barr virus (EBV) serology in lung transplant recipients with primary EBV infection and/or post-transplant lymphoproliferative disease. J Med Virol 2003 0.75
105 Bronchoalveolar lavage in a patient with recurrence of sarcoidosis after lung transplantation. J Heart Lung Transplant 2004 0.75