A young type III hyperlipoproteinemic patient associated with apolipoprotein E deficiency.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMID 2492364)

Published in Metabolism on February 01, 1989

Authors

H Mabuchi1, H Itoh, M Takeda, K Kajinami, T Wakasugi, J Koizumi, R Takeda, C Asagami

Author Affiliations

1: Department of Internal Medicine, Kanazawa University School of Medicine, Kanazawa, Japan.

Articles citing this

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci U S A (1992) 5.75

Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. JAMA Neurol (2014) 3.39

Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption. J Clin Invest (1994) 1.98

Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension. Proc Natl Acad Sci U S A (1995) 1.58

Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E. J Clin Invest (1993) 1.18

A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells. Proc Natl Acad Sci U S A (1994) 1.13

Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors. J Clin Invest (1995) 1.05

A 10-bp deletion in the apolipoprotein epsilon gene causing apolipoprotein E deficiency and severe type III hyperlipoproteinemia. Am J Hum Genet (1996) 0.95

Liver-directed gene transfer and prolonged expression of three major human ApoE isoforms in ApoE-deficient mice. J Clin Invest (1997) 0.93

Low-dose expression of a human apolipoprotein E transgene in macrophages restores cholesterol efflux capacity of apolipoprotein E-deficient mouse plasma. Proc Natl Acad Sci U S A (1998) 0.87

Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland. Exp Eye Res (2009) 0.84

Role of apolipoprotein E in neurodegenerative diseases. Neuropsychiatr Dis Treat (2015) 0.83

Severe xanthomatosis associated with familial apolipoprotein E deficiency. J Clin Pathol (1996) 0.79

ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis. J Lipid Res (2016) 0.76

Articles by these authors

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science (1998) 21.13

The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expression. EMBO J (1986) 19.59

Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet (1999) 13.67

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature (2000) 7.15

Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy (2010) 7.10

Green revolution: a mutant gibberellin-synthesis gene in rice. Nature (2002) 5.84

Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase. Nature (2001) 5.63

Nuclear genes encoding the yeast mitochondrial ATPase complex. Analysis of ATP1 coding the F1-ATPase alpha-subunit and its assembly. J Biol Chem (1986) 4.51

Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. Am J Respir Crit Care Med (2000) 4.32

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A (1981) 4.12

The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07

Genetic analysis of the attenuation phenotype of poliovirus type 1. J Virol (1986) 3.94

Structure and function of signal-transducing GTP-binding proteins. Annu Rev Biochem (1991) 3.48

Pharmacotherapy of Alzheimer's disease: is there a need to redefine treatment success? Int J Geriatr Psychiatry (2001) 3.09

Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med (1990) 3.02

Membrane conductance of an electroporated cell analyzed by submicrosecond imaging of transmembrane potential. Biophys J (1991) 3.01

Concern Early lung cancer action project: initial findings on repeat screenings. Cancer (2001) 2.99

Electroporation of cell membrane visualized under a pulsed-laser fluorescence microscope. Biophys J (1988) 2.83

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Proc Natl Acad Sci U S A (1986) 2.83

Preparation of giant liposomes in physiological conditions and their characterization under an optical microscope. Biophys J (1996) 2.74

Cardiac fibrosis in mice lacking brain natriuretic peptide. Proc Natl Acad Sci U S A (2000) 2.58

Isolation and characterization of the human Gs alpha gene. Proc Natl Acad Sci U S A (1988) 2.55

Transpedicular screw fixation for traumatic lesions of the middle and lower cervical spine: description of the techniques and preliminary report. J Spinal Disord (1994) 2.54

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucleic Acids Res (2000) 2.54

Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. Proc Natl Acad Sci U S A (1988) 2.54

Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A (1999) 2.38

Complex regulation of the TIR1/AFB family of auxin receptors. Proc Natl Acad Sci U S A (2009) 2.36

Dual-view microscopy with a single camera: real-time imaging of molecular orientations and calcium. J Cell Biol (1991) 2.30

In vitro phenotypic markers of a poliovirus recombinant constructed from infectious cDNA clones of the neurovirulent Mahoney strain and the attenuated Sabin 1 strain. J Virol (1985) 2.26

Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. Eur Respir J (1998) 2.23

Left-molar approach improves the laryngeal view in patients with difficult laryngoscopy. Anesthesiology (2000) 2.23

Antigenic variation and resistance to neutralization in poliovirus type 1. Science (1985) 2.19

Crazy-paving appearance at thin-section CT: spectrum of disease and pathologic findings. Radiology (1999) 2.16

Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the alpha subunit of mammalian G proteins. Proc Natl Acad Sci U S A (1987) 2.15

Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload. J Clin Invest (1995) 2.15

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol (1999) 2.14

Six chloroplast genes (ndhA-F) homologous to human mitochondrial genes encoding components of the respiratory chain NADH dehydrogenase are actively expressed: determination of the splice sites in ndhA and ndhB pre-mRNAs. Mol Gen Genet (1987) 2.14

Impaired expression of nitric oxide synthase in the gastric myenteric plexus of spontaneously diabetic rats. Gastroenterology (1997) 2.13

Pulmonary tuberculosis: CT findings--early active disease and sequential change with antituberculous therapy. Radiology (1993) 2.06

Direct observation of DNA rotation during transcription by Escherichia coli RNA polymerase. Nature (2001) 2.06

Dwarfism and early death in mice lacking C-type natriuretic peptide. Proc Natl Acad Sci U S A (2001) 1.99

Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth. Nat Cell Biol (2001) 1.95

Cervical pedicle screw insertion: assessment of safety and accuracy with computer-assisted image guidance. J Spinal Disord (2000) 1.95

Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. Cell (1998) 1.93

Stepping rotation of F1-ATPase visualized through angle-resolved single-fluorophore imaging. Proc Natl Acad Sci U S A (2000) 1.91

Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins. Nature (1989) 1.91

Pulmonary lymphangioleiomyomatosis: a report of 46 patients including a clinicopathologic study of prognostic factors. Am J Respir Crit Care Med (1995) 1.89

Endothelial nitric oxide synthase gene is positively associated with essential hypertension. Hypertension (1998) 1.88

Airway wall thickness in asthma assessed by computed tomography. Relation to clinical indices. Am J Respir Crit Care Med (2000) 1.88

Expression of a gibberellin 2-oxidase gene around the shoot apex is related to phase transition in rice. Plant Physiol (2001) 1.86

Time courses of cell electroporation as revealed by submicrosecond imaging of transmembrane potential. Biophys J (1993) 1.86

Genes for the eight ribosomal proteins are clustered on the chloroplast genome of tobacco (Nicotiana tabacum): similarity to the S10 and spc operons of Escherichia coli. Proc Natl Acad Sci U S A (1986) 1.83

Comparative analysis of RNA editing sites in higher plant chloroplasts. J Mol Evol (2001) 1.80

Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system". J Clin Invest (1992) 1.78

Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc Natl Acad Sci U S A (1992) 1.76

Pulmonary epithelioid haemangioendothelioma in 21 patients, including three with partial spontaneous regression. Eur Respir J (1998) 1.73

Tying a molecular knot with optical tweezers. Nature (1999) 1.73

Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: possible pathophysiological significance of VEGF in progression of atherosclerosis. Circulation (1998) 1.69

Cytomegalovirus DNA in the sera of patients with cytomegalovirus pneumonia. Br J Haematol (1991) 1.68

Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries. Circulation (2000) 1.65

Medial prefrontal cortex generates frontal midline theta rhythm. Neuroreport (1999) 1.64

Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging. Metabolism (2000) 1.63

A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ (2007) 1.63

New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet. Nat Med (1999) 1.62

Effect of an inhibitor of 3-hydroxy-3-methyglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia. N Engl J Med (1981) 1.61

Inhibition of hemolytic activity of the thermostable direct hemolysin of Vibrio parahaemolyticus by ganglioside. Infect Immun (1975) 1.61

An infectious cDNA clone of the poliovirus Sabin strain could be used as a stable repository and inoculum for the oral polio live vaccine. Virology (1986) 1.61

Increased serum concentrations of tissue inhibitor of metalloproteinase-1 in COPD patients. Eur Respir J (2005) 1.60

Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene. J Clin Invest (1994) 1.60

Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. E2020 Study Group. Dement Geriatr Cogn Disord (2001) 1.59

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration. J Neurosci (2000) 1.59

Incidence and distribution pattern of pelvic and paraaortic lymph node metastasis in patients with Stages IB, IIA, and IIB cervical carcinoma treated with radical hysterectomy. Cancer (1999) 1.57

Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. Atherosclerosis (1985) 1.55

Enzymic adenosine diphosphoribosylation of nuclear proteins. Cold Spring Harb Symp Quant Biol (1969) 1.54

Pore size of porous hydroxyapatite as the cell-substratum controls BMP-induced osteogenesis. J Biochem (1997) 1.52

A carcinoid tumor of the rectum removed by strip biopsy. Endoscopy (1993) 1.50

Urokinase type plasminogen activator receptor expression in colorectal neoplasms. Gut (1998) 1.50

Endoscopic sphincterotomy: long-term results in 408 patients with complete follow-up. Endoscopy (1988) 1.49

Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats. Dig Dis Sci (1990) 1.48

Helicobacter pylori infection reduces intraluminal nitric oxide in humans. J Gastroenterol (1999) 1.47

Role of interleukin-10 on hyporesponsiveness of endotoxin during surgery. Crit Care Med (2000) 1.47

Pressor response to compression of the ventrolateral medulla mediated by glutamate receptors. Hypertension (1999) 1.46

Heart and brain circulation and CO2 in healthy men. Acta Physiol (Oxf) (2008) 1.46

Effect of mental stress on plasma homovanillic acid in healthy human subjects. Neuropsychopharmacology (1998) 1.45

A study of DNA polymorphism in the apolipoprotein B gene in a Japanese population. Atherosclerosis (1988) 1.45

Three distinct forms of type 2A protein phosphatase in human erythrocyte cytosol. J Biol Chem (1988) 1.45

Genetic models reveal that brain natriuretic peptide can signal through different tissue-specific receptor-mediated pathways. Endocrinology (2000) 1.45

Analysis of stress-induced or salicylic acid-induced expression of the pathogenesis-related 1a protein gene in transgenic tobacco. Plant Cell (1990) 1.44

Regression of rectal polyps by indomethacin suppository in familial adenomatous polyposis. Report of two cases. Dis Colon Rectum (1994) 1.44

Respiratory failure in nemaline myopathy. Pediatr Neurol (1997) 1.43

Nuclear genes coding the yeast mitochondrial adenosine triphosphatase complex. Primary sequence analysis of ATP2 encoding the F1-ATPase beta-subunit precursor. J Biol Chem (1985) 1.42

Variable Bcl-2 phenotype in benign and malignant lesions of urothelium. Cancer Lett (1998) 1.42

Ectopic pancreas in the stomach presenting as an inflammatory abdominal mass. Am J Gastroenterol (1989) 1.41

Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction. Circulation (1995) 1.41

Protein chain initiation and deformylation in B. subtilis homogenates. Proc Natl Acad Sci U S A (1968) 1.41