Elevated copper in the amyloid plaques and iron in the cortex are observed in mouse models of Alzheimer's disease that exhibit neurodegeneration.

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Published in Biomed Spectrosc Imaging on April 01, 2013

Authors

Megan W Bourassa1, Andreana C Leskovjan2, Ryan V Tappero3, Erik R Farquhar4, Carol A Colton5, William E Van Nostrand6, Lisa M Miller7

Author Affiliations

1: Department of Chemistry, Stony Brook University, Stony Brook NY, USA.
2: Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA.
3: Photon Sciences Directorate, Brookhaven National Laboratory, Upton, NY, USA.
4: Center for Proteomics and Bioinformatics, Center for Synchrotron Biosciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
5: Department of Medicine, Division of Neurology, Duke University Medical Center, Durham, NC, USA.
6: Departments of Neurosurgery and Medicine, Stony Brook University, Stony Brook, NY, USA.
7: Department of Chemistry, Stony Brook University, Stony Brook NY, USA ; Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA ; Photon Sciences Directorate, Brookhaven National Laboratory, Upton, NY, USA.

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