Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48.

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🔗 View Article (PMID 24947287)

Published in Stroke on June 19, 2014

Authors

Robert P Giugliano1, Christian T Ruff2, Natalia S Rost2, Scott Silverman2, Stephen D Wiviott2, Cheryl Lowe2, Naveen Deenadayalu2, Sabina A Murphy2, Laura T Grip2, Joshua M Betcher2, Anil Duggal2, Jay Dave2, Minggao Shi2, Michele Mercuri2, Elliott M Antman2, Eugene Braunwald2, ENGAGE AF-TIMI 48 Investigators

Author Affiliations

1: From the Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., S.D.W., C.L., N.D., S.A.M., L.T.G., E.M.A., E.B.); Department of Neurology, Massachusetts General Hospital, Boston (N.S.R., S.S.); Biostatistics, Quintiles, Inc, Durham, NC (J.M.B.); and Daiichi Sankyo, Inc, Pharma Development, Edison, NJ (A.D., J.D., M.S., M.M.). rgiugliano@partners.org.
2: From the Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., S.D.W., C.L., N.D., S.A.M., L.T.G., E.M.A., E.B.); Department of Neurology, Massachusetts General Hospital, Boston (N.S.R., S.S.); Biostatistics, Quintiles, Inc, Durham, NC (J.M.B.); and Daiichi Sankyo, Inc, Pharma Development, Edison, NJ (A.D., J.D., M.S., M.M.).

Associated clinical trials:

Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation (EngageAFTIMI48) | NCT00781391