Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.

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Published in Nat Genet on June 22, 2014

Authors

Jamie M J Weaver1, Caryn S Ross-Innes1, Nicholas Shannon2, Andy G Lynch2, Tim Forshew2, Mariagnese Barbera1, Muhammed Murtaza2, Chin-Ann J Ong1, Pierre Lao-Sirieix1, Mark J Dunning2, Laura Smith1, Mike L Smith2, Charlotte L Anderson2, Benilton Carvalho2, Maria O'Donovan3, Timothy J Underwood4, Andrew P May5, Nicola Grehan1, Richard Hardwick6, Jim Davies7, Arusha Oloumi8, Sam Aparicio8, Carlos Caldas2, Matthew D Eldridge2, Paul A W Edwards9, Nitzan Rosenfeld2, Simon Tavaré2, Rebecca C Fitzgerald1, OCCAMS consortium

Author Affiliations

1: MRC Cancer Unit, University of Cambridge, Cambridge, UK.
2: CRUK Cambridge Institute, University of Cambridge, Cambridge, UK.
3: Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK.
4: Cancer Sciences Division, University of Southampton, Southampton, UK.
5: Fluidigm Corporation, South San Francisco, California, USA.
6: Oesophago-Gastric Unit, Addenbrooke's Hospital, Cambridge, UK.
7: Oxford ComLab, University of Oxford, UK.
8: British Columbia Cancer Research Centre, Cancer Agency Research Centre, Canada.
9: Department of Pathology, University of Cambridge, Cambridge, UK.

Associated clinical trials:

Evaluation of MicroRNA Expression in Blood and Cytology for Detecting Barrett's Esophagus and Associated Neoplasia | NCT02464930

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