Published in Clin Cancer Res on June 24, 2014
Decitabine rescues cisplatin resistance in head and neck squamous cell carcinoma. PLoS One (2014) 0.86
DNA Methylation Modulates Nociceptive Sensitization after Incision. PLoS One (2015) 0.78
What pain tells us about cancer. Pain (2015) 0.77
Neuron-restrictive silencer factor-mediated downregulation of μ-opioid receptor contributes to the reduced morphine analgesia in bone cancer pain. Pain (2017) 0.75
DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion. Pharmgenomics Pers Med (2017) 0.75
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain (1988) 18.17
Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia. J Clin Oncol (2009) 3.97
Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine. Proc Natl Acad Sci U S A (2010) 3.86
Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity. Nat Protoc (2007) 2.88
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proc Natl Acad Sci U S A (2005) 2.36
Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst (2003) 2.22
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res (Phila) (2008) 2.04
HSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathy. Gene Ther (2005) 1.63
Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain. Mol Ther (2004) 1.56
Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury. Nat Med (2003) 1.54
A prospective study of quality of life in head and neck cancer patients. Part I: at diagnosis. Laryngoscope (2001) 1.50
Zebularine: a new drug for epigenetic therapy. Biochem Soc Trans (2004) 1.49
Gene transfer of glutamic acid decarboxylase reduces neuropathic pain. Ann Neurol (2005) 1.47
Gene transfer to interfere with TNFalpha signaling in neuropathic pain. Gene Ther (2007) 1.37
HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain. Mol Pain (2006) 1.32
DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action. Curr Top Microbiol Immunol (2000) 1.31
Evaluation of pain in patients with oral squamous cell carcinoma. J Pain (2004) 1.29
Immune cell-derived beta-endorphin. Production, release, and control of inflammatory pain in rats. J Clin Invest (1997) 1.27
HSV-mediated transfer of interleukin-10 reduces inflammatory pain through modulation of membrane tumor necrosis factor alpha in spinal cord microglia. Gene Ther (2007) 1.22
Prevalence and management of pain in Italian patients with advanced non-small-cell lung cancer. Br J Cancer (2004) 1.20
Engineering an endomorphin-2 gene for use in neuropathic pain therapy. Pain (2007) 1.13
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells. Breast Cancer Res Treat (2009) 1.08
Down-regulation of mu opioid receptor expression within distinct subpopulations of dorsal root ganglion neurons in a murine model of bone cancer pain. Neuroscience (2007) 1.08
Decitabine. Recent Results Cancer Res (2010) 1.07
Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury. Eur J Pain (2011) 1.06
Effects of transgene-mediated endomorphin-2 in inflammatory pain. Eur J Pain (2008) 1.06
Mu-opiate receptor and Beta-endorphin expression in nerve endings and keratinocytes in human skin. Dermatology (2004) 1.04
Effect of peripheral endothelin-1 concentration on carcinoma-induced pain in mice. Eur J Pain (2007) 1.02
Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer. BMC Cancer (2008) 1.02
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology. Nucleosides Nucleotides Nucleic Acids (2005) 0.99
Functional expression of mu-opioid receptors in the human colon cancer cell line, HT-29, and their localization in human colon. Dig Dis Sci (2007) 0.97
Orofacial pain onset predicts transition to head and neck cancer. Pain (2011) 0.97
Endogenous opioids inhibit early-stage pancreatic pain in a mouse model of pancreatic cancer. Gastroenterology (2006) 0.96
Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat. Neuroscience (2010) 0.96
Naloxone acts as an antagonist of estrogen receptor activity in MCF-7 cells. Mol Cancer Ther (2006) 0.95
Opioid requirement, opioid receptor expression, and clinical outcomes in patients with advanced prostate cancer. Cancer (2013) 0.94
Re-expression of the methylated EDNRB gene in oral squamous cell carcinoma attenuates cancer-induced pain. Pain (2011) 0.92
Involvement of peripheral opioid receptors in electroacupuncture analgesia for carrageenan-induced hyperalgesia. Brain Res (2010) 0.90
Expression of mu-opiate receptor in human epidermis and keratinocytes. J Invest Dermatol (1998) 0.90
Characterization of mu-opiate receptor in human epidermis and keratinocytes. Ann N Y Acad Sci (1999) 0.85
Vector-mediated gene transfer to express inhibitory neurotransmitters in dorsal root ganglion reduces pain in a rodent model of lumbar radiculopathy. Spine (Phila Pa 1976) (2006) 0.83
Sensation of abdominal pain induced by peritoneal carcinomatosis is accompanied by changes in the expression of substance P and μ-opioid receptors in the spinal cord of mice. Anesthesiology (2012) 0.82
Development of HSV-mediated gene transfer for the treatment of chronic pain. Exp Neurol (2003) 0.81
Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model. Peptides (2010) 0.81
Continuous subcutaneous administration of high-dose salmon calcitonin in bone metastasis: pain control and beta-endorphin plasma levels. J Pain Symptom Manage (1999) 0.80
Mu and delta opioid receptor regulation of pro-opiomelanocortin peptide secretion from the rat neurointermediate pituitary in vitro. Neuropeptides (2000) 0.78
Plasma Beta-endorphin levels before and after relief of cancer pain. Pain Physician (2004) 0.77
Continuous subcutaneous octreotide in gastrointestinal cancer patients: pain control and beta-endorphin levels. Anticancer Res (2001) 0.77
Opioid antagonist-induced regulation of the mu-opioid receptor expression in MCF-7 breast cancer cell line. Endocr Regul (2009) 0.77