Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus.

Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters. Front Synaptic Neurosci (2016) 0.78

Electrophysiological Assessment of Serotonin and GABA Neuron Function in the Dorsal Raphe during the Third Trimester Equivalent Developmental Period in Mice(1,2,3). eNeuro (2016) 0.76

Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats. Eur Neuropsychopharmacol (2015) 0.76

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit. FASEB J (2002) 4.20

Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat Rev Neurosci (2005) 4.07

Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors. Proc Natl Acad Sci U S A (2004) 3.21

Specific GABAA circuits for visual cortical plasticity. Science (2004) 3.05

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors. Nature (2003) 2.47

Reversal of pathological pain through specific spinal GABAA receptor subtypes. Nature (2008) 2.30

How can drug discovery for psychiatric disorders be improved? Nat Rev Drug Discov (2007) 2.29

Neural bases for addictive properties of benzodiazepines. Nature (2010) 2.17

Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. Eur J Neurosci (2010) 2.03

Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics. J Neurosci (2005) 2.03

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms. J Neurosci (2003) 1.97

The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors. Neuropharmacology (2002) 1.85

The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J Pharmacol Exp Ther (2005) 1.82

Neurosteroid modulation of GABAA receptors. Prog Neurobiol (2003) 1.80

Essential role for TRPC5 in amygdala function and fear-related behavior. Cell (2009) 1.72

Spatiotemporal specificity of GABAA receptor-mediated regulation of adult hippocampal neurogenesis. Eur J Neurosci (2011) 1.68

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors. Nat Neurosci (2007) 1.62

Molecular determinants for the action of general anesthetics at recombinant alpha(2)beta(3)gamma(2)gamma-aminobutyric acid(A) receptors. J Neurochem (2002) 1.56

Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors. Pharmacol Ther (2007) 1.56

Specific subtypes of GABAA receptors mediate phasic and tonic forms of inhibition in hippocampal pyramidal neurons. J Neurophysiol (2006) 1.55

Neurosteroids: endogenous allosteric modulators of GABA(A) receptors. Psychoneuroendocrinology (2009) 1.52

Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Res (2004) 1.49

Major differences in inhibitory synaptic transmission onto two neocortical interneuron subclasses. J Neurosci (2003) 1.43

The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells. J Physiol (2007) 1.42

Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors. J Biol Chem (2006) 1.39

The involvement of hypothalamic sleep pathways in general anesthesia: testing the hypothesis using the GABAA receptor beta3N265M knock-in mouse. J Neurosci (2009) 1.37

R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit. Anesth Analg (2005) 1.33

Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors. Proc Natl Acad Sci U S A (2010) 1.27

Presynaptic alpha2-GABAA receptors in primary afferent depolarization and spinal pain control. J Neurosci (2011) 1.26

Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells. J Physiol (2011) 1.25

Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice. Pain (2008) 1.25

Requirement of alpha5-GABAA receptors for the development of tolerance to the sedative action of diazepam in mice. J Neurosci (2004) 1.25

Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteins. Methods Enzymol (2002) 1.24

GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts. Neuropharmacology (2008) 1.23

The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia. Neuropharmacology (2003) 1.22

GABA receptors containing the alpha5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear. Eur J Neurosci (2004) 1.21

Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesth Analg (2005) 1.19

Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors. J Physiol (2009) 1.19

Dynamic GABA(A) receptor subtype-specific modulation of the synchrony and duration of thalamic oscillations. J Neurosci (2003) 1.18

Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors. Eur J Neurosci (2009) 1.18

Neurosteroid modulation of GABAA receptors: molecular determinants and significance in health and disease. Neurochem Int (2007) 1.16

Molecular and systemic mechanisms of general anaesthesia: the 'multi-site and multiple mechanisms' concept. Curr Opin Anaesthesiol (2005) 1.15

GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus. J Neurophysiol (2008) 1.14

Anaesthetic drugs: linking molecular actions to clinical effects. Curr Pharm Des (2006) 1.14

Hooked on benzodiazepines: GABAA receptor subtypes and addiction. Trends Neurosci (2011) 1.13

Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor. Trends Pharmacol Sci (2005) 1.11

Identification of a molecular target mediating the general anesthetic actions of pentobarbital. Mol Pharmacol (2006) 1.11

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones. J Physiol (2007) 1.10

Alteration of GABAergic synapses and gephyrin clusters in the thalamic reticular nucleus of GABAA receptor alpha3 subunit-null mice. Eur J Neurosci (2006) 1.10

Characterization of the effects of charged residues in the intracellular loop on ion permeation in alpha1 glycine receptor channels. J Biol Chem (2008) 1.08

Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins. Mol Cell Neurosci (2002) 1.07

Analysis of the presence and abundance of GABAA receptors containing two different types of alpha subunits in murine brain using point-mutated alpha subunits. J Biol Chem (2004) 1.07

Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. J Biol Chem (2008) 1.07

Mapping the contribution of beta3-containing GABAA receptors to volatile and intravenous general anesthetic actions. BMC Pharmacol (2007) 1.06

Antidepressant-like properties of α2-containing GABA(A) receptors. Behav Brain Res (2010) 1.06

GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. J Physiol (2007) 1.05

A gain in GABAA receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures. Proc Natl Acad Sci U S A (2009) 1.05

Cellular correlate of assembly formation in oscillating hippocampal networks in vitro. Proc Natl Acad Sci U S A (2011) 1.05

Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor. J Biol Chem (2007) 1.05

Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress. Front Neurosci (2011) 1.04

Intrinsic and synaptic dynamics interact to generate emergent patterns of rhythmic bursting in thalamocortical neurons. J Neurosci (2006) 1.04

Tonic inhibition in principal cells of the amygdala: a central role for α3 subunit-containing GABAA receptors. J Neurosci (2012) 1.03

GABA-independent GABAA receptor openings maintain tonic currents. J Neurosci (2013) 1.00

Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor. Neuron (2013) 1.00

α2-containing GABA(A) receptors: a target for the development of novel treatment strategies for CNS disorders. Pharmacol Ther (2012) 1.00

Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. J Neurosci (2013) 1.00

Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains. J Neurosci (2005) 1.00

Phosphorylation influences neurosteroid modulation of synaptic GABAA receptors in rat CA1 and dentate gyrus neurones. Neuropharmacology (2003) 0.99

Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABA(A) receptor subtypes. Neuropharmacology (2011) 0.98

Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice. Neuropharmacology (2012) 0.97

Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology (2013) 0.97

Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response. J Neurosci (2013) 0.96

Diazepam-induced adaptive plasticity revealed by alpha1 GABAA receptor-specific expression profiling. J Neurochem (2004) 0.95

Diazepam and cocaine potentiate brain stimulation reward in C57BL/6J mice. Behav Brain Res (2009) 0.95

GABA receptor-mediated effects in the peripheral nervous system: A cross-interaction with neuroactive steroids. J Mol Neurosci (2006) 0.95

Differential roles of GABA(A) receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward. Neuropsychopharmacology (2012) 0.94

Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nat Commun (2013) 0.94

Distinct molecular targets for the central respiratory and cardiac actions of the general anesthetics etomidate and propofol. FASEB J (2005) 0.93

Regulation of cognition and symptoms of psychosis: focus on GABA(A) receptors and glycine transporter 1. Pharmacol Biochem Behav (2008) 0.93

Giant spontaneous depolarizing potentials in the developing thalamic reticular nucleus. J Neurophysiol (2007) 0.91

Rings of charge within the extracellular vestibule influence ion permeation of the 5-HT3A receptor. J Biol Chem (2011) 0.91

Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. J Neurosci (2014) 0.91