Published in Proc Natl Acad Sci U S A on July 02, 2014
Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers. PLoS One (2016) 1.39
Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system. Sci Rep (2015) 0.98
A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning. Elife (2017) 0.82
Genetic insights into the mechanisms of Fgf signaling. Genes Dev (2016) 0.79
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. Nat Commun (2017) 0.75
Advances in Understanding Hair Growth. F1000Res (2016) 0.75
Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process. Clin Cosmet Investig Dermatol (2017) 0.75
Genetic prediction of male pattern baldness. PLoS Genet (2017) 0.75
Activation and increase of radio-sensitive CD11b+ recruited Kupffer cells/macrophages in diet-induced steatohepatitis in FGF5 deficient mice. Sci Rep (2016) 0.75
A 1-bp deletion in Fgf5 causes male-dominant long hair in the Syrian hamster. Mamm Genome (2015) 0.75
Multiple-trait QTL mapping and genomic prediction for wool traits in sheep. Genet Sel Evol (2017) 0.75
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet (2011) 59.36
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res (2010) 43.51
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc (2009) 38.62
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Res (2011) 10.99
Predicting functional effect of human missense mutations using PolyPhen-2. Curr Protoc Hum Genet (2013) 6.67
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature (2012) 4.26
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin. Nature (2000) 3.90
HomozygosityMapper--an interactive approach to homozygosity mapping. Nucleic Acids Res (2009) 3.86
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Structural basis for FGF receptor dimerization and activation. Cell (1999) 3.19
FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations. Cell (1994) 3.10
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity. Cell (2000) 2.99
Coat variation in the domestic dog is governed by variants in three genes. Science (2009) 2.70
The hair cycle. J Cell Sci (2006) 2.58
Online system for faster multipoint linkage analysis via parallel execution on thousands of personal computers. Am J Hum Genet (2006) 2.04
Human hair growth in vitro. J Cell Sci (1990) 1.72
ENDOCRINE INFLUENCES ON HAIR GROWTH. Br Med J (1965) 1.43
Mutations within the FGF5 gene are associated with hair length in cats. Anim Genet (2007) 1.27
Four independent mutations in the feline fibroblast growth factor 5 gene determine the long-haired phenotype in domestic cats. J Hered (2007) 1.25
Short anagen syndrome. J Am Acad Dermatol (2005) 1.09
Niche crosstalk: intercellular signals at the hair follicle. Cell (2011) 1.06
Fibroblast growth factor 5 inhibits hair growth by blocking dermal papilla cell activation. Biochem Biophys Res Commun (2002) 1.03
Severe hypertension. Treatment with minoxidil. JAMA (1975) 1.03
Dual-mode regulation of hair growth cycle by two Fgf-5 gene products. J Invest Dermatol (2000) 0.99
Minoxidil and the treatment of severe hypertension. N Engl J Med (1980) 0.98
Recapitulation of four hypertension susceptibility genes (CSK, CYP17A1, MTHFR, and FGF5) in East Asians. Metabolism (2012) 0.95
Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5. Oncogene (1993) 0.93
Localization of rat FGF-5 protein in skin macrophage-like cells and FGF-5S protein in hair follicle: possible involvement of two Fgf-5 gene products in hair growth cycle regulation. J Invest Dermatol (1998) 0.91
An alternatively spliced fibroblast growth factor (FGF)-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity. J Biol Chem (1998) 0.90
Anatomy and physiology of eyelash follicles: relevance to lash ablation procedures. Ophthal Plast Reconstr Surg (1997) 0.88
Manipulation of outer root sheath cell survival perturbs the hair-growth cycle. EMBO J (1999) 0.86
Association of common variants in/near six genes (ATP2B1, CSK, MTHFR, CYP17A1, STK39 and FGF5) with blood pressure/hypertension risk in Chinese children. J Hum Hypertens (2013) 0.86
Human eyelash characterization. Br J Dermatol (2009) 0.85
The angora locus (go) in the mouse: hair morphology, duration of growth cycle and site of action. Genet Res (1984) 0.81
Commentary: From serendipity to pilot study and then pivotal trial: bimatoprost topical for eyelash growth. Dermatol Surg (2010) 0.80
The prostamide-related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias. FASEB J (2012) 0.79
Familial trichomegaly. Arch Ophthalmol (1997) 0.77
Eyelash trichomegaly: review of congenital, acquired, and drug-associated etiologies for elongation of the eyelashes. Int J Dermatol (2012) 0.77
The hair cycle on the human thigh and upper arm. Br J Dermatol (1985) 0.77