Published in ChemMedChem on July 02, 2014
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Novel ceftazidime-resistance beta-lactamases generated by a codon-based mutagenesis method and selection. Nucleic Acids Res (2002) 0.96
Multiple multicomponent macrocyclizations (MiBs): a strategic development toward macrocycle diversity. Chem Rev (2009) 0.91
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Multiple multicomponent macrocyclizations including bifunctional building blocks (MiBs) based on Staudinger and Passerini three-component reactions. J Org Chem (2008) 0.88
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Transcriptional profiling of fetal hypothalamic TRH neurons. BMC Genomics (2011) 0.83
Diversity oriented one-pot synthesis of complex macrocycles: very large steroid-peptoid hybrids from multiple multicomponent reactions including bifunctional building blocks. Angew Chem Int Ed Engl (2005) 0.82
Parathyroid hormone-related protein(1-34) regulates Phex expression in osteoblasts through the protein kinase A pathway. Endocrinology (2003) 0.81
Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release. Peptides (2008) 0.81
An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells. Brain Res Brain Res Protoc (2002) 0.80
Rapid access to N-substituted diketopiperazines by one-pot Ugi-4CR/deprotection+activation/cyclization (UDAC). J Comb Chem (2009) 0.80
The Krüppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development. Mol Cell Endocrinol (2010) 0.80
The PKC and ERK/MAPK pathways regulate glucocorticoid action on TRH transcription. Neurochem Res (2008) 0.80
Voluntary exercise adapts the hypothalamus-pituitary-thyroid axis in male rats. Endocrinology (2014) 0.79
Plasmodium falciparum M1-aminopeptidase: a promising target for the development of antimalarials. Curr Drug Targets (2014) 0.79
Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioral paradigms producing varying intensities of stress and physical activity. Regul Pept (2012) 0.78
Creb and Sp/Krüppel response elements cooperate to control rat TRH gene transcription in response to cAMP. Biochim Biophys Acta (2011) 0.78
3,3',5'-triiodo-L-thyronine reduces efficiency of mRNA knockdown by antisense oligodeoxynucleotides: a study with pyroglutamyl aminopeptidase II in adenohypophysis. Oligonucleotides (2004) 0.77
Freezing imine exchange in dynamic combinatorial libraries with Ugi reactions: versatile access to templated macrocycles. Org Lett (2007) 0.77
New insights into the structure-cytotoxicity relationship of spirostan saponins and related glycosides. Bioorg Med Chem (2012) 0.77
Synthesis of steroid-biaryl ether hybrid macrocycles with high skeletal and side chain variability by multiple multicomponent macrocyclization including bifunctional building blocks. J Org Chem (2006) 0.77
A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity. J Neurochem (2005) 0.77
Homology modeling and site-directed mutagenesis of pyroglutamyl peptidase II. Insights into omega-versus aminopeptidase specificity in the M1 family. J Biol Chem (2006) 0.76
Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin-releasing hormone in the rat medial septum. J Pharmacol Exp Ther (2012) 0.76
Effect of divalent cations on the porcine kidney cortex membrane-bound form of dipeptidyl peptidase IV. Int J Biochem Cell Biol (2010) 0.76
Improvement of an unusual twin-arginine transporter leader peptide by a codon-based randomization approach. Appl Environ Microbiol (2006) 0.75
The acute response of the amygdalar TRH system to psychogenic stressors varies dependent on the paradigm and circadian condition. Brain Res (2012) 0.75
T3 differentially regulates TRH expression in developing hypothalamic neurons in vitro. Brain Res (2009) 0.75
Effect of C-ring modifications on the cytotoxicity of spirostan saponins and related glycosides. Bioorg Med Chem (2012) 0.75
Effect of zinc and calcium ions on the rat kidney membrane-bound form of dipeptidyl peptidase IV. J Biosci (2013) 0.75
Carbohydrate-steroid conjugation by Ugi reaction: one-pot synthesis of triple sugar/pseudo-peptide/spirostane hybrids. Carbohydr Res (2012) 0.75
Organocatalytic asymmetric epoxidation and tandem epoxidation/Passerini reaction under eco-friendly reaction conditions. Org Biomol Chem (2012) 0.75
Expanding the Scope of Ugi Multicomponent Bioconjugation to Produce Pneumococcal Multivalent Glycoconjugates as Vaccine Candidates. Bioconjug Chem (2020) 0.75
Bidirectional macrocyclization of peptides by double multicomponent reactions. Org Biomol Chem (2015) 0.75
A Codon Deletion at the Beginning of Green Fluorescent Protein Genes Enhances Protein Expression. J Mol Microbiol Biotechnol (2016) 0.75
Multicomponent synthesis of Ugi-type ceramide analogues and neoglycolipids from lipidic isocyanides. J Org Chem (2012) 0.75
Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis. Eur J Endocrinol (2002) 0.75
Multicomponent ligation of steroids: creating diversity at the linkage moiety of bis-spirostanic conjugates by Ugi reactions. ACS Comb Sci (2013) 0.75
NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus. Neurosci Lett (2008) 0.75
A multicomponent macrocyclization strategy to natural product-like cyclic lipopeptides: synthesis and anticancer evaluation of surfactin and mycosubtilin analogues. Org Biomol Chem (2017) 0.75
Multicomponent combinatorial development and conformational analysis of prolyl peptide-peptoid hybrid catalysts: application in the direct asymmetric Michael addition. J Org Chem (2013) 0.75
Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD+ regeneration. Biotechnol Lett (2007) 0.75