Published in Cell on July 03, 2014
Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation. Mol Cell (2015) 2.05
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome. Cell Metab (2014) 1.85
Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia. J Clin Invest (2014) 1.63
Stem cells and the impact of ROS signaling. Development (2014) 1.10
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. Elife (2016) 1.03
Protein lysine acetylation by p300/CBP. Chem Rev (2015) 1.02
Nuclear DNA damage signalling to mitochondria in ageing. Nat Rev Mol Cell Biol (2016) 0.99
The rate of glycolysis quantitatively mediates specific histone acetylation sites. Cancer Metab (2015) 0.99
Protein acetylation in metabolism - metabolites and cofactors. Nat Rev Endocrinol (2015) 0.97
TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions. Mol Cell (2015) 0.97
Metabolic control of epigenetics in cancer. Nat Rev Cancer (2016) 0.94
Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes. Mol Cell (2016) 0.93
A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors. Invest New Drugs (2015) 0.91
A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity. Nat Cell Biol (2015) 0.90
Mechanisms by which different functional states of mitochondria define yeast longevity. Int J Mol Sci (2015) 0.87
Metabolic regulation of histone post-translational modifications. ACS Chem Biol (2015) 0.87
Metabolic control of methylation and acetylation. Curr Opin Chem Biol (2015) 0.86
Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity. Nat Commun (2015) 0.85
Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor. Nucleic Acids Res (2015) 0.84
Metabolism and epigenetics: a link cancer cells exploit. Curr Opin Biotechnol (2014) 0.84
Exploring the emerging complexity in transcriptional regulation of energy homeostasis. Nat Rev Genet (2015) 0.83
Protein acetylation and acetyl coenzyme a metabolism in budding yeast. Eukaryot Cell (2014) 0.83
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch. Cell Rep (2016) 0.82
Defining the potential antidepressant mode of action of acetyl-l-carnitine. Proc Natl Acad Sci U S A (2016) 0.81
Metformin targets histone acetylation in cancer-prone epithelial cells. Cell Cycle (2016) 0.81
Understanding the acetylome: translating targeted proteomics into meaningful physiology. Am J Physiol Cell Physiol (2014) 0.80
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Impact of acetylation on tumor metabolism. Mol Cell Oncol (2014) 0.78
Role of mitochondrial dysfunction in cancer progression. Exp Biol Med (Maywood) (2016) 0.77
Defining the orphan functions of lysine acetyltransferases. ACS Chem Biol (2015) 0.77
Abnormal Glucose Metabolism in Alzheimer's Disease: Relation to Autophagy/Mitophagy and Therapeutic Approaches. Neurochem Res (2015) 0.77
Microbiota and Neurological Disorders: A Gut Feeling. Biores Open Access (2016) 0.76
Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence. Biochem J (2016) 0.76
Activation of AMP-activated Protein Kinase by Metformin Induces Protein Acetylation in Prostate and Ovarian Cancer Cells. J Biol Chem (2016) 0.76
A mitochondrial expatriate: nuclear pyruvate dehydrogenase. Cell (2014) 0.75
Compartmentation of metabolites in regulating epigenome of cancer. Mol Med (2016) 0.75
A cancerous web: signaling, metabolism, and the epigenome. Mol Cell Oncol (2014) 0.75
A nuclear sensor of mitochondrial function. Oncotarget (2015) 0.75
Undercover: gene control by metabolites and metabolic enzymes. Genes Dev (2016) 0.75
Nuclear Phosphoproteomic Screen Uncovers ACLY as Mediator of IL-2-induced Proliferation of CD4+ T lymphocytes. Mol Cell Proteomics (2016) 0.75
Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging. Front Genet (2016) 0.75
Histone modification as a reflection of metabolism. Cell Cycle (2016) 0.75
Succinyl-proteome profiling of a high taxol containing hybrid Taxus species (Taxus × media) revealed involvement of succinylation in multiple metabolic pathways. Sci Rep (2016) 0.75
Mitochondrial metabolites: undercover signalling molecules. Interface Focus (2017) 0.75
H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis. Nat Commun (2017) 0.75
The interplay of post-translational modification and gene therapy. Drug Des Devel Ther (2016) 0.75
Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation. Cell (2017) 0.75
Role of Natural Radiosensitizers and Cancer Cell Radioresistance: An Update. Anal Cell Pathol (Amst) (2016) 0.75
Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae. J Biol Chem (2017) 0.75
Mitochondrial determinants of cancer health disparities. Semin Cancer Biol (2017) 0.75
Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin. Transl Res (2017) 0.75
Msn2/4 regulate expression of glycolytic enzymes and control transition from quiescence to growth. Elife (2017) 0.75