Published in Neurochem Res on July 05, 2014
Drowning stars: reassessing the role of astrocytes in brain edema. Trends Neurosci (2014) 1.13
Molecular pathophysiology of cerebral edema. J Cereb Blood Flow Metab (2015) 0.89
miR-320a affects spinal cord edema through negatively regulating aquaporin-1 of blood-spinal cord barrier during bimodal stage after ischemia reperfusion injury in rats. BMC Neurosci (2016) 0.79
Systemic pro-inflammatory response facilitates the development of cerebral edema during short hypoxia. J Neuroinflammation (2016) 0.77
Pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica. Acta Neuropathol (2017) 0.75
Today's Approach to Treating Brain Swelling in the Neuro Intensive Care Unit. Semin Neurol (2016) 0.75
Aquaporin-4: A Potential Therapeutic Target for Cerebral Edema. Int J Mol Sci (2016) 0.75
Progress in AQP Research and New Developments in Therapeutic Approaches to Ischemic and Hemorrhagic Stroke. Int J Mol Sci (2016) 0.75
Aquaporin 4-Mediated Glutamate-Induced Astrocyte Swelling Is Partially Mediated through Metabotropic Glutamate Receptor 5 Activation. Front Cell Neurosci (2017) 0.75
Current AQP research: therapeutic approaches to ischemic and hemorrhagic stroke. Neural Regen Res (2016) 0.75
Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci (2006) 12.23
Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science (1992) 9.09
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med (2012) 8.04
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med (2000) 6.27
Structural basis of water-specific transport through the AQP1 water channel. Nature (2002) 6.23
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci (1997) 5.68
Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature (2010) 5.47
Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J Neurophysiol (1966) 5.21
Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J Neurosci (2002) 5.14
Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain (2007) 4.50
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters. Physiol Rev (2005) 4.29
Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J (2004) 3.80
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem (1984) 3.39
Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol (2007) 3.33
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. Proc Natl Acad Sci U S A (1994) 3.20
The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science (1989) 3.14
Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. J Neurosci (1996) 2.90
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. Proc Natl Acad Sci U S A (2001) 2.88
Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nat Med (2006) 2.57
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci (2005) 2.48
Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. J Neurosci (2007) 2.44
Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space. Brain Res (1985) 2.43
Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia (2006) 2.39
An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci U S A (2003) 2.37
Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg (1990) 2.28
Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance. Proc Natl Acad Sci U S A (2009) 2.28
Aquaporin water channels in the nervous system. Nat Rev Neurosci (2013) 2.10
Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of alpha-syntrophin-null mice. Proc Natl Acad Sci U S A (2003) 2.06
Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol (2003) 1.99
Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. J Neurosci (1990) 1.98
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice. Proc Natl Acad Sci U S A (2002) 1.97
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J Neurosci (2004) 1.90
Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. J Neurosci (2008) 1.87
Aquaporin-4 deficiency in skeletal muscle and brain of dystrophic mdx mice. FASEB J (2001) 1.84
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. J Biol Chem (2004) 1.82
Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB J (2006) 1.72
AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neuroscience (2009) 1.70
Impaired hearing in mice lacking aquaporin-4 water channels. J Biol Chem (2001) 1.68
Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke. Stroke (2008) 1.64
A new look at cerebrospinal fluid circulation. Fluids Barriers CNS (2014) 1.62
Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke. J Cereb Blood Flow Metab (2004) 1.56
Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. J Neurosci (2003) 1.55
Pathophysiological aspects of brain edema. Acta Neuropathol (1987) 1.54
Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation. FASEB J (2011) 1.50
Cell swelling and a nonselective cation channel regulated by internal Ca2+ and ATP in native reactive astrocytes from adult rat brain. J Neurosci (2001) 1.50
Cotransport of K+, Cl- and H2O by membrane proteins from choroid plexus epithelium of Necturus maculosus. J Physiol (1994) 1.49
Ion regulation in the brain: implications for pathophysiology. Neuroscientist (2002) 1.47
The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury. J Neurosurg (2010) 1.46
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet. Proc Natl Acad Sci U S A (2011) 1.44
Activity-dependent shrinkage of extracellular space in rat optic nerve: a developmental study. J Neurosci (1985) 1.39
Increased seizure threshold in mice lacking aquaporin-4 water channels. Neuroreport (2004) 1.38
'Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation. J Cereb Blood Flow Metab (2013) 1.37
Functional and molecular characterization of the human neutral solute channel aquaporin-9. Am J Physiol (1999) 1.37
Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling. J Biol Chem (2008) 1.37
Brain water mobility decreases after astrocytic aquaporin-4 inhibition using RNA interference. J Cereb Blood Flow Metab (2010) 1.31
Aquaporin-4 regulates extracellular space volume dynamics during high-frequency synaptic stimulation: a gene deletion study in mouse hippocampus. Glia (2012) 1.29
Is there a cerebral lymphatic system? Stroke (2013) 1.29
Protective role of early aquaporin 4 induction against postischemic edema formation. J Cereb Blood Flow Metab (2008) 1.26
Studies of cerebrospinal fluid flow and penetration into brain following lateral ventricle and cisterna magna injections of the tracer [14C]inulin in rat. Neuroscience (2000) 1.25
Membrane organization and function of M1 and M23 isoforms of aquaporin-4 in epithelial cells. Am J Physiol Renal Physiol (2004) 1.24
Inhibition of Na(+)-K(+)-Cl(-) cotransporter during focal cerebral ischemia decreases edema and neuronal damage. Brain Res (2003) 1.23
Cotransport of water by the Na+-K+-2Cl(-) cotransporter NKCC1 in mammalian epithelial cells. J Physiol (2010) 1.23
Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia. Invest Ophthalmol Vis Sci (2004) 1.22
Ontogeny of water transport in rat brain: postnatal expression of the aquaporin-4 water channel. Eur J Neurosci (1999) 1.20
Distribution of Aquaporin 9 in the adult rat brain: preferential expression in catecholaminergic neurons and in glial cells. Neuroscience (2004) 1.19
The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel. J Biol Chem (2012) 1.18
Directed spatial potassium redistribution in rat neocortex. Glia (2000) 1.17
Impact of aquaporin-4 channels on K+ buffering and gap junction coupling in the hippocampus. Glia (2011) 1.17
Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release. Am J Physiol Cell Physiol (2002) 1.14
Insights into TRPM4 function, regulation and physiological role. Handb Exp Pharmacol (2007) 1.14
Intracellular pH regulation in cultured astrocytes from rat hippocampus. II. Electrogenic Na/HCO3 cotransport. J Gen Physiol (1997) 1.13
Water transport in the brain: role of cotransporters. Neuroscience (2004) 1.12
Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: possible role in edema resolution? Neuroscience (2012) 1.12
Intracellular sodium homeostasis in rat hippocampal astrocytes. J Physiol (1996) 1.11
Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)](o)- induced swelling and EAA release in astrocytes. Am J Physiol Cell Physiol (2002) 1.10
Intracellular pH regulation in cultured astrocytes from rat hippocampus. I. Role Of HCO3-. J Gen Physiol (1997) 1.07
New isoforms of rat Aquaporin-4. Genomics (2008) 1.06
Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice. Am J Physiol Cell Physiol (2004) 1.06
Activity-dependent glial swelling is impaired in aquaporin-4 knockout mice. Neurosci Res (2009) 1.06
AQP4 knockout impairs proliferation, migration and neuronal differentiation of adult neural stem cells. J Cell Sci (2008) 1.02
Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet. Eur J Neurosci (2011) 1.02
Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses. Glia (2014) 1.00
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier. Glia (2011) 1.00
Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury. J Neurochem (2011) 0.99
NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf/MEK/MAPK cascade. Crit Care Med (2008) 0.98
Glial swelling during extracellular acidosis in vitro. Stroke (1988) 0.98
Assembly of a perivascular astrocyte protein scaffold at the mammalian blood-brain barrier is dependent on alpha-syntrophin. Glia (2006) 0.97
Laminar-specific and developmental expression of aquaporin-4 in the mouse hippocampus. Neuroscience (2011) 0.97
Agrin defines polarized distribution of orthogonal arrays of particles in astrocytes. Cell Tissue Res (2009) 0.97
Evidence for electrogenic sodium-bicarbonate cotransport in cultured rat cerebellar astrocytes. Pflugers Arch (1994) 0.96
Functional and molecular interactions between aquaporins and Na,K-ATPase. Neuroscience (2009) 0.96
Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes. J Cell Sci (2012) 0.95
Regulation of Na(+)-K(+)-Cl(-) cotransporter in primary astrocytes by dibutyryl cAMP and high [K(+)](o). Am J Physiol Cell Physiol (2000) 0.95
Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. Glia (2012) 0.95
Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI). J Neurol Sci (2012) 0.95
Ionic mechanisms in glutamate-induced astrocyte swelling: role of K+ influx. J Neurosci Res (1998) 0.95
Regulation of AQP4 surface expression via vesicle mobility in astrocytes. Glia (2013) 0.94
In vivo expression of aquaporin-4 by reactive microglia. J Neurochem (2004) 0.94
Gene inactivation of Na+/H+ exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia. Eur J Neurosci (2008) 0.92
Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol (2007) 3.33
Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nat Med (2006) 2.57
Alternative splicing of cGMP-dependent protein kinase I in angiotensin-hypertension: novel mechanism for nitrate tolerance in vascular smooth muscle. Circ Res (2003) 2.35
Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke. Stroke (2007) 2.10
Long-term outcome of Gamma Knife stereotactic radiosurgery for arteriovenous malformations graded by the Spetzler-Martin classification. J Neurosurg (2012) 2.03
Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury. J Clin Invest (2007) 1.84
Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage. J Cereb Blood Flow Metab (2008) 1.77
Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke. Stroke (2008) 1.64
Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. J Neurosci (2003) 1.55
Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke. Stroke (2010) 1.52
De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury. Nat Med (2009) 1.42
Cytotoxic edema: mechanisms of pathological cell swelling. Neurosurg Focus (2007) 1.41
Sulfonylurea receptor 1 in central nervous system injury: a focused review. J Cereb Blood Flow Metab (2012) 1.39
Glial fibrillary acidic protein is highly correlated with brain injury. J Trauma (2008) 1.30
Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma. Sci Transl Med (2010) 1.28
Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion. J Neurotrauma (2009) 1.27
Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport. Physiology (Bethesda) (2009) 1.24
Novel treatment targets for cerebral edema. Neurotherapeutics (2012) 1.20
Progesterone in traumatic brain injury. N Engl J Med (2015) 1.20
The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel. J Biol Chem (2012) 1.18
Hemorrhagic progression of a contusion after traumatic brain injury: a review. J Neurotrauma (2011) 1.17
Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas. Ann Neurol (2012) 1.14
Comparative effects of glibenclamide and riluzole in a rat model of severe cervical spinal cord injury. Exp Neurol (2011) 1.11
Glibenclamide-10-h Treatment Window in a Clinically Relevant Model of Stroke. Transl Stroke Res (2012) 1.10
Towards a Meso-Scale SMA-Actuated MRI-Compatible Neurosurgical Robot. IEEE Trans Robot (2011) 1.09
Rodent model of direct cranial blast injury. J Neurotrauma (2011) 1.08
Drugs acting on SUR1 to treat CNS ischemia and trauma. Curr Opin Pharmacol (2007) 1.08
Sulfonylurea receptor 1 expression in human cerebral infarcts. J Neuropathol Exp Neurol (2013) 1.08
Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury. J Neuropathol Exp Neurol (2010) 1.06
Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8. J Cereb Blood Flow Metab (2011) 1.04
Non-selective cation channels, transient receptor potential channels and ischemic stroke. Biochim Biophys Acta (2007) 1.03
Transient receptor potential melastatin 4 and cell death. Pflugers Arch (2012) 1.02
Novel model of frontal impact closed head injury in the rat. J Neurotrauma (2009) 1.01
Heparin reduces neuroinflammation and transsynaptic neuronal apoptosis in a model of subarachnoid hemorrhage. Transl Stroke Res (2012) 1.00
Transforming growth factor-beta 1 regulates Kir2.3 inward rectifier K+ channels via phospholipase C and protein kinase C-delta in reactive astrocytes from adult rat brain. J Biol Chem (2001) 1.00
Molecular mechanisms of microvascular failure in central nervous system injury--synergistic roles of NKCC1 and SUR1/TRPM4. J Neurosurg (2010) 0.99
Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage. Stroke (2013) 0.97
EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients. Am J Physiol Cell Physiol (2006) 0.96
Glibenclamide for the treatment of acute CNS injury. Pharmaceuticals (Basel) (2013) 0.96
Does inhibiting Sur1 complement rt-PA in cerebral ischemia? Ann N Y Acad Sci (2012) 0.96
Adenylate cyclase 5 and KCa1.1 channel are required for EGFR up-regulation of PCNA in native contractile rat basilar artery smooth muscle. J Physiol (2005) 0.96
Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema. Transl Stroke Res (2013) 0.96
Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease. Stroke (2006) 0.96
Comparative study of decompressive craniectomy after mass lesion evacuation in severe head injury. Neurosurgery (2009) 0.92
Fetal and ovarian radiation dose in patients undergoing gamma knife radiosurgery. Surg Neurol (2002) 0.91
Mislocalization of eNOS and upregulation of cerebral vascular Ca2+ channel activity in angiotensin-hypertension. Hypertension (2003) 0.91
Activation of (Na+ + K+)-ATPase modulates cardiac L-type Ca2+ channel function. Mol Pharmacol (2009) 0.90
Craniectomy for malignant cerebral infarction: prevalence and outcomes in US hospitals. PLoS One (2011) 0.89
Pilot study of intravenous glyburide in patients with a large ischemic stroke. Stroke (2013) 0.88
The protective effect of glibenclamide in a model of hemorrhagic encephalopathy of prematurity. Brain Sci (2013) 0.88
Plasma levels of the beta chemokine regulated upon activation, normal T cell expressed, and secreted (RANTES) correlate with severe brain injury. J Trauma (2008) 0.87
Augmented bladder urothelial polyamine signaling and block of BK channel in the pathophysiology of overactive bladder syndrome. Am J Physiol Cell Physiol (2009) 0.87
Complex N-glycosylation stabilizes surface expression of transient receptor potential melastatin 4b protein. J Biol Chem (2013) 0.86
Increased transient receptor potential vanilloid type 1 (TRPV1) signaling in idiopathic overactive bladder urothelial cells. Neurourol Urodyn (2011) 0.86
Spinal cord injury with unilateral versus bilateral primary hemorrhage--effects of glibenclamide. Exp Neurol (2011) 0.86
Inflammation of the choroid plexus and ependymal layer of the ventricle following intraventricular hemorrhage. Transl Stroke Res (2011) 0.86
Exploratory analysis of glyburide as a novel therapy for preventing brain swelling. Neurocrit Care (2014) 0.86
Sulfonylurea receptor 1 in the germinal matrix of premature infants. Pediatr Res (2008) 0.84
Chlorotoxin-sensitive Ca2+-activated Cl- channel in type R2 reactive astrocytes from adult rat brain. Glia (2003) 0.83
Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans. Neurosurg Focus (2014) 0.83
Early pathophysiological changes in cerebral vessels predisposing to stroke. Clin Hemorheol Microcirc (2003) 0.83
Adenosine-A2a receptor down-regulates cerebral smooth muscle L-type Ca2+ channel activity via protein tyrosine phosphatase, not cAMP-dependent protein kinase. Mol Pharmacol (2003) 0.82
Glibenclamide in cerebral ischemia and stroke. Neurocrit Care (2014) 0.82
Intramedullary lesion expansion on magnetic resonance imaging in patients with motor complete cervical spinal cord injury. J Neurosurg Spine (2012) 0.82
Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage. Crit Care Med (2016) 0.81
Increase in Cx45 gap junction channels in cerebral smooth muscle cells from SHR. Hypertension (2002) 0.81
Letter by Simard et al regarding article, "Sulfonylurea use before stroke does not influence outcome". Stroke (2011) 0.81
Tandem insults of prenatal ischemia plus postnatal raised intrathoracic pressure in a novel rat model of encephalopathy of prematurity. J Neurosurg Pediatr (2011) 0.80
Traumatic brain injury. Curr Opin Crit Care (2009) 0.80
Exposure of the thorax to a sublethal blast wave causes a hydrodynamic pulse that leads to perivenular inflammation in the brain. J Neurotrauma (2014) 0.80
Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts. J Neuropathol Exp Neurol (2015) 0.80
Cell-Based Therapy in TBI: Magnetic Retention of Neural Stem Cells In Vivo. Cell Transplant (2015) 0.80
Biomarkers as outcome predictors in subarachnoid hemorrhage--a systematic review. Biomarkers (2014) 0.80
Outcomes in severe middle cerebral artery ischemic stroke. Neurocrit Care (2014) 0.80
cGMP-dependent and not cAMP-dependent kinase is required for adenosine-induced dilation of intracerebral arterioles. J Cardiovasc Pharmacol (2003) 0.80