Published in Am J Physiol Cell Physiol on October 22, 2003
Aquaporin water channels in the nervous system. Nat Rev Neurosci (2013) 2.10
Aquaporins and cell migration. Pflugers Arch (2007) 2.02
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. Bioorg Med Chem (2008) 1.75
A new look at cerebrospinal fluid circulation. Fluids Barriers CNS (2014) 1.62
Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation. FASEB J (2011) 1.50
Physiological roles of aquaporin-4 in brain. Physiol Rev (2013) 1.48
Aquaporins: important but elusive drug targets. Nat Rev Drug Discov (2014) 1.45
Real-time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices and in vivo revealed by two-photon microscopy. Glia (2009) 1.42
Altered astrocytic swelling in the cortex of α-syntrophin-negative GFAP/EGFP mice. PLoS One (2014) 1.40
Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking. Mol Biol Cell (2008) 1.38
Probing tissue microstructure with restriction spectrum imaging: Histological and theoretical validation. Hum Brain Mapp (2012) 1.37
Water permeability of Na+-K+-2Cl- cotransporters in mammalian epithelial cells. J Physiol (2005) 1.32
Aquaporins: translating bench research to human disease. J Exp Biol (2009) 1.31
Mammalian aquaporins: diverse physiological roles and potential clinical significance. Expert Rev Mol Med (2008) 1.31
Deletion of astroglial connexins weakens the blood-brain barrier. J Cereb Blood Flow Metab (2012) 1.30
Aquaporin-4 independent Kir4.1 K+ channel function in brain glial cells. Mol Cell Neurosci (2007) 1.22
Extracellular space diffusion in central nervous system: anisotropic diffusion measured by elliptical surface photobleaching. Biophys J (2005) 1.20
Impaired olfaction in mice lacking aquaporin-4 water channels. FASEB J (2008) 1.19
Automated cell-based assay for screening of aquaporin inhibitors. Anal Chem (2009) 1.06
Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation. J Gen Physiol (2013) 1.06
Knock-out models reveal new aquaporin functions. Handb Exp Pharmacol (2009) 1.02
Evidence against involvement of aquaporin-4 in cell-cell adhesion. J Mol Biol (2008) 1.02
Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion. Proc Natl Acad Sci U S A (2005) 0.97
Biology of AQP4 and anti-AQP4 antibody: therapeutic implications for NMO. Brain Pathol (2013) 0.96
Aquaporins in development -- a review. Reprod Biol Endocrinol (2005) 0.94
Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia. FASEB J (2013) 0.93
Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo. Glia (2008) 0.93
Aquaporin-1 tunes pain perception by interaction with Na(v)1.8 Na+ channels in dorsal root ganglion neurons. J Biol Chem (2009) 0.91
Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia. Neurosci Lett (2014) 0.91
Selective vasopressin-1a receptor antagonist prevents brain edema, reduces astrocytic cell swelling and GFAP, V1aR and AQP4 expression after focal traumatic brain injury. Brain Res (2014) 0.90
Reversible, temperature-dependent supramolecular assembly of aquaporin-4 orthogonal arrays in live cell membranes. Biophys J (2009) 0.90
Mechanisms of astrocyte-mediated cerebral edema. Neurochem Res (2014) 0.90
The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins. Glia (2015) 0.89
Molecular pathophysiology of cerebral edema. J Cereb Blood Flow Metab (2015) 0.89
Kurtosis analysis of neural diffusion organization. Neuroimage (2014) 0.86
Aquaporin and vascular diseases. Curr Neuropharmacol (2010) 0.86
Aquaporin-1-facilitated keratocyte migration in cell culture and in vivo corneal wound healing models. Exp Eye Res (2009) 0.86
Characterization of regulatory volume behavior by fluorescence quenching in human corneal epithelial cells. J Membr Biol (2005) 0.86
When can AQP4 assist transporter-mediated K⁺ uptake? J Gen Physiol (2013) 0.85
Very high aquaporin-1 facilitated water permeability in mouse gallbladder. Am J Physiol Gastrointest Liver Physiol (2009) 0.84
Neuromyelitis optica IgG stimulates an immunological response in rat astrocyte cultures. Glia (2014) 0.84
How astrocyte networks may contribute to cerebral metabolite clearance. Sci Rep (2015) 0.83
The impact of alpha-syntrophin deletion on the changes in tissue structure and extracellular diffusion associated with cell swelling under physiological and pathological conditions. PLoS One (2013) 0.83
Aquaporins as diagnostic and therapeutic targets in cancer: how far we are? J Transl Med (2015) 0.83
Changes in retinal aquaporin-9 (AQP9) expression in glaucoma. Biosci Rep (2013) 0.83
Detecting Aquaporin Function and Regulation. Front Chem (2016) 0.83
Expression of the Astrocyte Water Channel Aquaporin-4 in the Mouse Brain. ASN Neuro (2015) 0.82
GABA Not Only a Neurotransmitter: Osmotic Regulation by GABA(A)R Signaling. Front Cell Neurosci (2012) 0.82
Aquaporin and blood brain barrier. Curr Neuropharmacol (2010) 0.81
Cell volume and sodium content in rat kidney collecting duct principal cells during hypotonic shock. J Biophys (2008) 0.81
Disruption of dystroglycan-laminin interactions modulates water uptake by astrocytes. Brain Res (2013) 0.80
Immunohistochemical examination of intracerebral aquaporin-4 expression and its application for differential diagnosis between freshwater and saltwater drowning. Int J Legal Med (2010) 0.80
Cell-specific differential modulation of human trabecular meshwork cells by selective adenosine receptor agonists. Exp Eye Res (2006) 0.79
Increased differentiation capacity of bone marrow-derived mesenchymal stem cells in aquaporin-5 deficiency. Stem Cells Dev (2012) 0.79
The multifaceted role of astrocytes in regulating myelination. Exp Neurol (2016) 0.79
Activation of P2Y receptors causes strong and persistent shrinkage of C11-MDCK renal epithelial cells. Am J Physiol Cell Physiol (2011) 0.77
Regional registration of [6-(14)C]glucose metabolism during brain activation of α-syntrophin knockout mice. J Neurochem (2013) 0.77
Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel. Chem Biol Drug Des (2016) 0.77
AQP1 mediates water transport in the carotid body. Pflugers Arch (2010) 0.77
Salt and osmosensing: role of cytoplasmic hydrogel. Pflugers Arch (2015) 0.76
Roles of AQP5/AQP5-G103D in carbamylcholine-induced volume decrease and in reduction of the activation energy for water transport by rat parotid acinar cells. Pflugers Arch (2012) 0.76
Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance. J Am Soc Nephrol (2014) 0.76
Dynamic regulation of aquaporin-4 water channels in neurological disorders. Croat Med J (2015) 0.75
Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice. Glia (2015) 0.75
A Nanoscale Interface Promoting Molecular and Functional Differentiation of Neural Cells. Sci Rep (2016) 0.75
Computing Osmotic Permeabilities of Aquaporins AQP4, AQP5, and GlpF from Near-Equilibrium Simulations. Biochim Biophys Acta (2017) 0.75
Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression. Exp Ther Med (2015) 0.75
Ultraviolet Irradiation-Induced Volume Alteration of Corneal Epithelial Cells. Invest Ophthalmol Vis Sci (2016) 0.75
Aquaporins in Brain Edema and Neuropathological Conditions. Int J Mol Sci (2016) 0.75
Aquaporin-Targeted Therapeutics: State-of-the-Field. Adv Exp Med Biol (2017) 0.75
Human Mesenchymal Stem Cells from Adipose Tissue Differentiated into Neuronal or Glial Phenotype Express Different Aquaporins. Mol Neurobiol (2016) 0.75
A mathematical model of the cell volume regulation in a hypotonic medium. Dokl Biol Sci (2011) 0.75
Role of the low-selective organic anion transport in regulation of osmotic balance of renal collecting duct principal cells under hypo-osmotic conditions. Dokl Biol Sci (2017) 0.75
Effect of hypoosmotic shock on the volume of renal collecting duct epithelial cells of brattleboro rats with hereditarily defective vasopressin synthesis. Dokl Biochem Biophys (2013) 0.75
Cell volume regulation of rat kidney collecting duct epithelial cells in hypotonic medium. Dokl Biol Sci (2011) 0.75
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med (2005) 10.39
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med (2000) 6.27
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest (2002) 4.97
Tracking of single fluorescent particles in three dimensions: use of cylindrical optics to encode particle position. Biophys J (1994) 4.77
Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus. J Cell Biol (1997) 4.53
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem (2003) 4.40
Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature (2005) 4.20
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening. J Clin Invest (2005) 4.19
Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain (2010) 3.95
Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J (2004) 3.80
Green fluorescent protein as a noninvasive intracellular pH indicator. Biophys J (1998) 3.61
Classification of traumatic brain injury for targeted therapies. J Neurotrauma (2008) 3.58
Determinants of the translational mobility of a small solute in cell cytoplasm. J Cell Biol (1993) 3.46
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest (1997) 3.45
Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem (2000) 3.29
Very early administration of progesterone for acute traumatic brain injury. N Engl J Med (2014) 3.20
Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry (2003) 3.12
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol (2004) 3.10
Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem (1998) 3.00
Crowding effects on diffusion in solutions and cells. Annu Rev Biophys (2008) 3.00
Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem (1999) 2.91
Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis. Kidney Int (2006) 2.89
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J Biol Chem (1994) 2.85
Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein. Cell Stress Chaperones (1996) 2.80
Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc Natl Acad Sci U S A (1998) 2.73
Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry. J Cell Biol (1991) 2.73
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem (2010) 2.66
Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophys J (1999) 2.59
Aquaporin 4 and neuromyelitis optica. Lancet Neurol (2012) 2.58
Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem (1997) 2.56
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. J Cell Sci (1995) 2.55
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci (2005) 2.48
Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol (2012) 2.45
Guidelines for the management of severe traumatic brain injury. I. Blood pressure and oxygenation. J Neurotrauma (2007) 2.39
Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia (2006) 2.39
Green fluorescent protein-based halide indicators with improved chloride and iodide affinities. FEBS Lett (2001) 2.38
Mechanism and cellular applications of a green fluorescent protein-based halide sensor. J Biol Chem (2000) 2.38
Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc Natl Acad Sci U S A (1995) 2.37
Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med (2008) 2.34
Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol (2005) 2.32
Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. J Biol Chem (2003) 2.25
Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem (2002) 2.24
Localization of the CHIP28 water channel in rat kidney. Am J Physiol (1992) 2.17
Upregulation of TRPC1 in the development of cardiac hypertrophy. J Mol Cell Cardiol (2006) 2.17
Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol (2002) 2.16
The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells. J Biol Chem (1996) 2.16
Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J Neurotrauma (2007) 2.15
Rapid diffusion of green fluorescent protein in the mitochondrial matrix. J Cell Biol (1998) 2.12
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity. Proc Natl Acad Sci U S A (2001) 2.10
Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem (2005) 2.08
Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J (2006) 2.07
Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest (2000) 2.07
Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury. Brain (2008) 2.06
Aquaporins and cell migration. Pflugers Arch (2007) 2.02
Water and urea permeability properties of Xenopus oocytes: expression of mRNA from toad urinary bladder. Am J Physiol (1991) 2.01
Monte Carlo analysis of obstructed diffusion in three dimensions: application to molecular diffusion in organelles. Biophys J (1998) 2.00
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. J Biol Chem (2001) 1.99
CFTR: folding, misfolding and correcting the ΔF508 conformational defect. Trends Mol Med (2011) 1.99
Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. J Biol Chem (2011) 1.98
K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods (2005) 1.98
Analysis of fluorophore diffusion by continuous distributions of diffusion coefficients: application to photobleaching measurements of multicomponent and anomalous diffusion. Biophys J (1998) 1.95
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A (2000) 1.94
Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry (2003) 1.93
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J Neurosci (2004) 1.90
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. J Biol Chem (2002) 1.89
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.87
Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones. J Clin Invest (1998) 1.87
Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. J Neurosci (2008) 1.87
Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci U S A (1998) 1.85
Functional reconstitution of the isolated erythrocyte water channel CHIP28. J Biol Chem (1992) 1.85
Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Mol Pharmacol (2007) 1.85
Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. J Cell Biol (1993) 1.84
Three-dimensional organization of a human water channel. Nature (1997) 1.83
Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am J Physiol (1996) 1.82
Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH. J Clin Invest (2001) 1.80
Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol Pharmacol (2005) 1.80
Cytoplasmic viscosity near the cell plasma membrane: translational diffusion of a small fluorescent solute measured by total internal reflection-fluorescence photobleaching recovery. Biophys J (1996) 1.79
Two cases of calcified amorphous tumor mimicking mitral valve vegetation. Circulation (2012) 1.79
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. J Biol Chem (2002) 1.79
Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. J Cell Sci (1997) 1.78
Coagulopathy after traumatic brain injury. Neurosurgery (2012) 1.78
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. Bioorg Med Chem (2008) 1.75
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways. FASEB J (2004) 1.75
Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts. J Cell Biol (1992) 1.74
Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB J (2006) 1.72
Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity. Biophys J (1990) 1.72
Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol (2011) 1.72
Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea. FASEB J (2010) 1.71
AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neuroscience (2009) 1.70
Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem (2000) 1.70
Clinical trials in traumatic brain injury: past experience and current developments. Neurotherapeutics (2010) 1.69
Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions. Mol Biol Cell (2006) 1.69
New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience (2004) 1.69