Published in Radiat Res on July 08, 2014
Immunobiology of radiotherapy: new paradigms. Radiat Res (2014) 0.84
Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med (2010) 67.34
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med (2011) 26.90
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science (2006) 24.54
Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med (2000) 16.20
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13.90
The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer (2012) 10.90
Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med (2006) 10.54
Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med (2012) 8.46
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med (2005) 6.37
Costimulation blockade with belatacept in renal transplantation. N Engl J Med (2005) 4.86
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med (2006) 4.84
Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med (2003) 4.67
Etanercept as monotherapy in patients with psoriasis. N Engl J Med (2003) 4.57
Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Int J Radiat Oncol Biol Phys (2004) 4.29
Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer. Clin Cancer Res (2005) 4.23
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant (2005) 4.05
Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science (2013) 3.25
Combining radiotherapy and cancer immunotherapy: a paradigm shift. J Natl Cancer Inst (2013) 3.07
Cancer classification using the Immunoscore: a worldwide task force. J Transl Med (2012) 2.88
Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nat Immunol (2001) 2.83
Whole body irradiation; radiobiology or medicine? Br J Radiol (1953) 2.80
The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Res (2011) 2.60
Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. J Immunol (2003) 2.51
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome. Proc Natl Acad Sci U S A (2007) 2.37
Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys (2013) 2.28
Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity. J Immunol (2008) 1.93
Phase 1 study of stereotactic body radiotherapy and interleukin-2--tumor and immunological responses. Sci Transl Med (2012) 1.61
Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Res (1999) 1.60
From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer. Curr Opin Immunol (2013) 1.55
The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas. Clin Cancer Res (2006) 1.51
Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types. Clin Cancer Res (2013) 1.51
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell. Proc Natl Acad Sci U S A (2005) 1.49
The crystal structure of the costimulatory OX40-OX40L complex. Structure (2006) 1.44
Fast on-rates allow short dwell time ligands to activate T cells. Proc Natl Acad Sci U S A (2010) 1.43
Anti-TNF-α agents in the treatment of immune-mediated inflammatory diseases: mechanisms of action and pitfalls. Immunotherapy (2010) 1.35
Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154. Eur J Immunol (2001) 1.33
The additional facet of immunoscore: immunoprofiling as a possible predictive tool for cancer treatment. J Transl Med (2013) 1.31
NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family. Immunity (2006) 1.27
Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines. J Virol (2006) 1.18
Structure of CD84 provides insight into SLAM family function. Proc Natl Acad Sci U S A (2007) 1.17
HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function. Proc Natl Acad Sci U S A (2013) 1.12
Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function. Proc Natl Acad Sci U S A (2007) 1.11
Sequence, structure, function, immunity: structural genomics of costimulation. Immunol Rev (2009) 1.08
Etanercept: An overview. J Am Acad Dermatol (2003) 1.06
B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets. J Immunol (2012) 1.04
"Peptabody": a new type of high avidity binding protein. Proc Natl Acad Sci U S A (1997) 1.00
On the roles of polyvalent binding in immune recognition: perspectives in the nanoscience of immunology and the immune response to nanomedicines. Adv Drug Deliv Rev (2012) 0.90
An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy. PLoS One (2012) 0.89
Protein production from the structural genomics perspective: achievements and future needs. Curr Opin Struct Biol (2013) 0.88
CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells. Cancer Immunol Immunother (2012) 0.86
Anti-TNF-alpha therapy for ankylosing spondylitis--a specific or nonspecific treatment? N Engl J Med (2002) 0.85
Affinity and cross-reactivity engineering of CTLA4-Ig to modulate T cell costimulation. J Immunol (2012) 0.84
Etanercept. Immunex. Curr Opin Investig Drugs (2001) 0.84
Tumor necrosis factor inhibitors in the management of juvenile idiopathic arthritis: an evidence-based review. Paediatr Drugs (2010) 0.82
Costimulation blockade with belatacept in renal transplantation. N Engl J Med (2005) 0.77
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization. Oncogene (2003) 2.27
TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors. J Clin Oncol (2004) 2.09
Identification of adult hepatic progenitor cells capable of repopulating injured rat liver. Hepatology (2008) 1.93
Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice. PLoS One (2009) 1.55
Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol (2013) 1.49
Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat. J Hepatol (2008) 1.47
A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers. J Biol Chem (2007) 1.47
Barriers to the successful treatment of liver disease by hepatocyte transplantation. J Hepatol (2010) 1.41
Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges. Oncology (Williston Park) (2008) 1.38
Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant (2012) 1.31
Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation. Hepatology (2009) 1.23
Bone marrow stromal cell transplantation mitigates radiation-induced gastrointestinal syndrome in mice. PLoS One (2011) 1.19
Combination therapy with local radiofrequency ablation and systemic vaccine enhances antitumor immunity and mediates local and distal tumor regression. PLoS One (2013) 1.14
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase. J Biol Chem (2010) 1.14
Hyperthermia on immune regulation: a temperature's story. Cancer Lett (2008) 1.12
Bone marrow progenitors are not the source of expanding oval cells in injured liver. Stem Cells (2004) 1.10
Conformal radiotherapy for hepatocellular carcinoma. Crit Rev Oncol Hematol (2008) 1.03
Neandertal and Denisovan retroviruses. Curr Biol (2012) 1.02
TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome. PLoS One (2012) 1.00
Localized hyperthermia combined with intratumoral dendritic cells induces systemic antitumor immunity. Cancer Res (2007) 0.99
Correction of hyperoxaluria by liver repopulation with hepatocytes in a mouse model of primary hyperoxaluria type-1. Transplantation (2008) 0.98
Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes. J Clin Invest (2011) 0.96
T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice. Mutagenesis (2013) 0.96
Radiation-induced modulation of costimulatory and coinhibitory T-cell signaling molecules on human prostate carcinoma cells promotes productive antitumor immune interactions. Cancer Biother Radiopharm (2014) 0.95
Detection of Human Endogenous Retrovirus K (HERV-K) Transcripts in Human Prostate Cancer Cell Lines. Front Oncol (2013) 0.94
Opportunities and challenges in the era of molecularly targeted agents and radiation therapy. J Natl Cancer Inst (2013) 0.93
Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine (2012) 0.92
Transition state analogues in quorum sensing and SAM recycling. Nucleic Acids Symp Ser (Oxf) (2008) 0.92
Patterns of failure after the multimodality treatment of uterine papillary serous carcinoma. Int J Radiat Oncol Biol Phys (2003) 0.91
Angiostatin inhibits and regresses corneal neovascularization. Arch Ophthalmol (2002) 0.91
Liver repopulation: a new concept of hepatocyte transplantation. Surg Today (2005) 0.91
Stem cell therapies for the treatment of radiation-induced normal tissue side effects. Antioxid Redox Signal (2014) 0.90
Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice. Hepatology (2006) 0.90
Flt3L therapy following localized tumor irradiation generates long-term protective immune response in metastatic lung cancer: its implication in designing a vaccination strategy. Oncology (2006) 0.90
Hepatocellular carcinoma: radiation therapy. Cancer J (2008) 0.89
An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy. PLoS One (2012) 0.89
Predictive value of linear-quadratic model in the treatment of cervical cancer using high-dose-rate brachytherapy. Int J Radiat Oncol Biol Phys (2002) 0.89
Lessons learned from radiation oncology clinical trials. Clin Cancer Res (2013) 0.89
Combined immunotherapy with Listeria monocytogenes-based PSA vaccine and radiation therapy leads to a therapeutic response in a murine model of prostate cancer. Cancer Immunol Immunother (2012) 0.88
Role of cysteine residues in the function of human UDP glucuronosyltransferase isoform 1A1 (UGT1A1). Biochem J (2005) 0.88
Systemic administration of reovirus (Reolysin) inhibits growth of human sarcoma xenografts. Cancer (2010) 0.87
Single liver lobe repopulation with wildtype hepatocytes using regional hepatic irradiation cures jaundice in Gunn rats. PLoS One (2012) 0.86
Who benefits from adjuvant radiation therapy for gastric cancer? A meta-analysis. Int J Radiat Oncol Biol Phys (2013) 0.86
Immunobiology of radiotherapy: new paradigms. Radiat Res (2014) 0.84
Biological impact of geometric uncertainties: what margin is needed for intra-hepatic tumors? Radiat Oncol (2010) 0.84
Harnessing the potential of radiation-induced immune modulation for cancer therapy. Cancer Immunol Res (2013) 0.84
Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon. Hepatology (2009) 0.83
An autologous in situ tumor vaccination approach for hepatocellular carcinoma. 1. Flt3 ligand gene transfer increases antitumor effects of a radio-inducible suicide gene therapy in an ectopic tumor model. Radiat Res (2014) 0.83
The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice. Radiat Res (2015) 0.81
Proposal for a Simple and Efficient Monthly Quality Management Program Assessing the Consistency of Robotic Image-Guided Small Animal Radiation Systems. Health Phys (2015) 0.80
ICRU reference dose in an era of intensity-modulated radiation therapy clinical trials: correlation with planning target volume mean dose and suitability for intensity-modulated radiation therapy dose prescription. Radiother Oncol (2008) 0.79
Variant splicing and influence of ionizing radiation on human endogenous retrovirus K (HERV-K) transcripts in cancer cell lines. PLoS One (2013) 0.78
Prevention of hepatocyte allograft rejection in rats by transferring adenoviral early region 3 genes into donor cells. Hepatology (2007) 0.77
Experience of micromultileaf collimator linear accelerator based single fraction stereotactic radiosurgery: tumor dose inhomogeneity, conformity, and dose fall off. Med Phys (2011) 0.77
Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology. Cell Transplant (2016) 0.76
Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury. Stem Cell Res (2013) 0.76
Liver regeneration and energetic changes in rats following hepatic radiation therapy and hepatocyte transplantation by ³¹P MRSI. Liver Int (2014) 0.75
Precision Medicine and Pancreatic Cancer: A Gemcitabine Pathway Approach. Pancreas (2016) 0.75
Dosimetry Formalism and Implementation of a Homogenous Irradiation Protocol to Improve the Accuracy of Small Animal Whole-Body Irradiation Using a 137Cs Irradiator. Health Phys (2016) 0.75
Progressive transition from pre-planned to intraoperative optimizing seed implant: post implementation analysis. J Contemp Brachytherapy (2012) 0.75
Obtaining normal tissue constraints using intensity modulated radiotherapy (IMRT) in patients with oral cavity, oropharyngeal, and laryngeal carcinoma. Med Dosim (2008) 0.75
Construction of liver tissue in vivo with preparative partial hepatic irradiation and growth stimulus: investigations of less invasive techniques and progenitor cells. J Surg Res (2013) 0.75
Timing of postseed imaging influences rectal dose-volume parameters for cesium-131 prostate seed implants. Brachytherapy (2011) 0.75