From innate to adaptive immune response in muscular dystrophies and skeletal muscle regeneration: the role of lymphocytes.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 4083765)

Published in Biomed Res Int on June 16, 2014

Authors

Luca Madaro1, Marina Bouché2

Author Affiliations

1: IRCCS Fondazione Santa Lucia, Via del Fosso di Fiorano 64, 00143 Rome, Italy.
2: DAHFMO, Unit of Histology and Medical Embryology, Sapienza University of Rome, Via Antonio Scarpa 14, 00161 Rome, Italy.

Articles cited by this

(truncated to the top 100)

Alternative activation of macrophages. Nat Rev Immunol (2003) 27.53

Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 24.36

Satellite cell of skeletal muscle fibers. J Biophys Biochem Cytol (1961) 11.41

Macrophage biology in development, homeostasis and disease. Nature (2013) 8.28

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science (2007) 8.07

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J Exp Med (2007) 7.87

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J Leukoc Biol (2007) 7.80

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat Cell Biol (2010) 5.84

Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J Immunol (1993) 5.16

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle. Nat Cell Biol (2010) 4.57

IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell (2003) 3.80

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. J Exp Med (1988) 3.50

Regulatory interactions between muscle and the immune system during muscle regeneration. Am J Physiol Regul Integr Comp Physiol (2010) 3.44

A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice. J Cell Biol (2001) 3.41

Randomized, double-blind six-month trial of prednisone in Duchenne's muscular dystrophy. N Engl J Med (1989) 3.32

Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science (2010) 3.31

A special population of regulatory T cells potentiates muscle repair. Cell (2013) 3.09

Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab (2008) 3.00

Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell (2013) 3.00

AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration. Cell Metab (2013) 2.92

TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell (2010) 2.89

Niche regulation of muscle satellite cell self-renewal and differentiation. Cell Stem Cell (2008) 2.83

Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy. J Exp Med (2005) 2.82

Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice. Cell (2010) 2.43

Duchenne muscular dystrophy: continuous noninvasive ventilatory support prolongs survival. Respir Care (2011) 2.33

The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma. Circ Res (2004) 2.29

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy. Hum Mol Genet (2008) 2.27

Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice. J Cell Biol (2003) 2.12

Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol (2006) 2.12

Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-beta. J Clin Invest (2009) 2.10

Helper (CD4(+)) and cytotoxic (CD8(+)) T cells promote the pathology of dystrophin-deficient muscle. Clin Immunol (2001) 1.94

Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. Am J Physiol Regul Integr Comp Physiol (2006) 1.94

Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae. Proc Natl Acad Sci U S A (1986) 1.93

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J Exp Med (2004) 1.88

Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle. PLoS Biol (2004) 1.87

Nfix regulates fetal-specific transcription in developing skeletal muscle. Cell (2010) 1.84

Regulatory factors and cell populations involved in skeletal muscle regeneration. J Cell Physiol (2010) 1.83

Dysferlin and muscle membrane repair. Curr Opin Cell Biol (2007) 1.82

IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration. J Immunol (2012) 1.81

MCP-1 deficiency causes altered inflammation with impaired skeletal muscle regeneration. J Leukoc Biol (2006) 1.76

Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice. J Immunol (2006) 1.65

Myonuclear apoptosis in dystrophic mdx muscle occurs by perforin-mediated cytotoxicity. J Clin Invest (1997) 1.61

Reduced necrosis of dystrophic muscle by depletion of host neutrophils, or blocking TNFalpha function with Etanercept in mdx mice. Neuromuscul Disord (2006) 1.57

Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes. J Immunol (1985) 1.53

Aberrant muscle antigen exposure in mice is sufficient to cause myositis in a Treg cell-deficient milieu. Arthritis Rheum (2013) 1.49

p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair. J Cell Biol (2011) 1.43

Interleukin-6/signal transducer and activator of transcription 3 (STAT3) pathway is essential for macrophage infiltration and myoblast proliferation during muscle regeneration. J Biol Chem (2012) 1.41

Macrophage plasticity and the role of inflammation in skeletal muscle repair. Mediators Inflamm (2013) 1.40

Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction. Am J Physiol Cell Physiol (2007) 1.39

ErbB2 is required for muscle spindle and myoblast cell survival. Mol Cell Biol (2002) 1.39

PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice. J Clin Invest (2009) 1.37

Inactivation of PKCtheta leads to increased susceptibility to obesity and dietary insulin resistance in mice. Am J Physiol Endocrinol Metab (2006) 1.34

Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications. Am J Physiol Endocrinol Metab (2012) 1.30

Analysis of T cell receptor repertoire of muscle-infiltrating T lymphocytes in polymyositis. Restricted V alpha/beta rearrangements may indicate antigen-driven selection. J Clin Invest (1993) 1.23

Immunobiology of muscle: advances in understanding an immunological microenvironment. Trends Immunol (2005) 1.23

Specific T cell receptor gene rearrangements at the site of muscle degeneration in Duchenne muscular dystrophy. J Immunol (1994) 1.23

Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration. FEBS J (2013) 1.22

Diaphragm rescue alone prevents heart dysfunction in dystrophic mice. Hum Mol Genet (2010) 1.19

T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse. J Pathol (2007) 1.16

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice. EMBO Mol Med (2013) 1.16

Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom. Muscle Nerve (2003) 1.15

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis. J Immunol (2006) 1.13

Eosinophilia of dystrophin-deficient muscle is promoted by perforin-mediated cytotoxicity by T cell effectors. Am J Pathol (2000) 1.11

Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy. Hum Mol Genet (2008) 1.11

Prednisolone decreases cellular adhesion molecules required for inflammatory cell infiltration in dystrophin-deficient skeletal muscle. Neuromuscul Disord (2004) 1.11

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo. Mol Immunol (2009) 1.10

Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle. Mol Med (2011) 1.09

Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy. Nat Cell Biol (2013) 1.07

Null mutation of gp91phox reduces muscle membrane lysis during muscle inflammation in mice. J Physiol (2003) 1.06

Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle. J Immunol (2005) 1.06

Dysregulated intracellular signaling and inflammatory gene expression during initial disease onset in Duchenne muscular dystrophy. Am J Phys Med Rehabil (2009) 1.02

Cromolyn administration (to block mast cell degranulation) reduces necrosis of dystrophic muscle in mdx mice. Neurobiol Dis (2006) 1.02

Recruitment of mast cells to muscle after mild damage. J Neurol Sci (1996) 1.01

Idiopathic inflammatory myopathies. J Neuroimmunol (2010) 0.99

Upregulated inducible co-stimulator (ICOS) and ICOS-ligand in inclusion body myositis muscle: significance for CD8+ T cell cytotoxicity. Brain (2004) 0.97

Peripheral tolerance in CD8+ T cells. Cytokine (2009) 0.96

Effects of T-lymphocyte depletion on muscle fibrosis in the mdx mouse. Am J Pathol (2005) 0.96

Skeletal muscle stem cells express anti-apoptotic ErbB receptors during activation from quiescence. Exp Cell Res (2006) 0.96

Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway. J Immunol (2012) 0.96

Paired immunoglobulin-like receptor A is an intrinsic, self-limiting suppressor of IL-5-induced eosinophil development. Nat Immunol (2013) 0.93

PKCθ signaling is required for myoblast fusion by regulating the expression of caveolin-3 and β1D integrin upstream focal adhesion kinase. Mol Biol Cell (2011) 0.93

Differential immunohistological features of inflammatory myopathies and dysferlinopathy. J Korean Med Sci (2009) 0.93

Null mutation of myeloperoxidase in mice prevents mechanical activation of neutrophil lysis of muscle cell membranes in vitro and in vivo. J Physiol (2005) 0.93

Protein kinase C theta co-operates with calcineurin in the activation of slow muscle genes in cultured myogenic cells. J Cell Physiol (2006) 0.92

Intracellular signaling in ER stress-induced autophagy in skeletal muscle cells. FASEB J (2013) 0.91

Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles. Muscle Nerve (2010) 0.90

Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation. Stem Cells (2014) 0.89

Mononuclear cell analysis of muscle biopsies in prednisone- and azathioprine-treated Duchenne muscular dystrophy. Neurology (1993) 0.89

Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the αMβ2 leukocyte integrin receptor. Hum Mol Genet (2012) 0.89

Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy. BMC Musculoskelet Disord (2010) 0.88

Monocyte depletion increases local proliferation of macrophage subsets after skeletal muscle injury. BMC Musculoskelet Disord (2013) 0.88

Regulators of chromatin state and transcription in CD4 T-cell polarization. Immunology (2013) 0.87

Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model. Exp Cell Res (2012) 0.86

PKC theta ablation improves healing in a mouse model of muscular dystrophy. PLoS One (2012) 0.85

Activated lymphocytes secretome inhibits differentiation and induces proliferation of C2C12 myoblasts. Cell Physiol Biochem (2014) 0.85

The Rag2⁻Il2rb⁻Dmd⁻ mouse: a novel dystrophic and immunodeficient model to assess innovating therapeutic strategies for muscular dystrophies. Mol Ther (2013) 0.84

Ventilatory chemosensory drive is blunted in the mdx mouse model of Duchenne Muscular Dystrophy (DMD). PLoS One (2013) 0.83

Protein kinase C theta plays a fundamental role in different types of chronic colitis. Gastroenterology (2007) 0.83

Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model. Arthritis Rheum (2012) 0.82

Constitutive and cytokine-induced expression of MHC and intercellular adhesion molecule-1 (ICAM-1) on human myoblasts. J Neuroimmunol (2001) 0.81

Articles by these authors

Inflammation in muscle repair, aging, and myopathies. Biomed Res Int (2014) 0.76