Published in Hum Mol Genet on March 01, 2012
Factor XIII activity mediates red blood cell retention in venous thrombi. J Clin Invest (2014) 1.18
Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients. Hum Mol Genet (2014) 1.05
Understanding the process of fibrosis in Duchenne muscular dystrophy. Biomed Res Int (2014) 1.00
Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skelet Muscle (2014) 0.89
Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism. Blood (2016) 0.87
From innate to adaptive immune response in muscular dystrophies and skeletal muscle regeneration: the role of lymphocytes. Biomed Res Int (2014) 0.85
Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy. Physiol Rev (2016) 0.85
Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function. FASEB J (2014) 0.84
Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade. EBioMedicine (2015) 0.84
Fibrin accumulation secondary to loss of plasmin-mediated fibrinolysis drives inflammatory osteoporosis in mice. Arthritis Rheumatol (2014) 0.82
P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy. PLoS Med (2015) 0.78
Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease. J Neurosci (2017) 0.75
Expression of intercellular adhesion molecule-1 by myofibers in mdx mice. Muscle Nerve (2015) 0.75
The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science (1989) 6.80
PTC124 targets genetic disorders caused by nonsense mutations. Nature (2007) 6.67
Direct isolation of satellite cells for skeletal muscle regeneration. Science (2005) 6.59
Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature (2006) 5.83
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature (1991) 5.40
Inflammatory processes in muscle injury and repair. Am J Physiol Regul Integr Comp Physiol (2005) 4.47
Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity. J Exp Med (1984) 4.00
Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage. Cell (1995) 3.53
A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice. J Cell Biol (2001) 3.41
Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice. Genes Dev (1995) 3.27
Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models. Curr Opin Genet Dev (2002) 3.15
rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice. Nat Med (2006) 3.13
Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment. Trends Cell Biol (2005) 2.74
Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping. Science (2004) 2.71
Muscle stem cells in development, regeneration, and disease. Genes Dev (2006) 2.67
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo. J Clin Invest (2004) 2.57
Aberrant repair and fibrosis development in skeletal muscle. Skelet Muscle (2011) 2.41
Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease. Neuron (2010) 2.37
Evans Blue Dye as an in vivo marker of myofibre damage: optimising parameters for detecting initial myofibre membrane permeability. J Anat (2002) 2.33
Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J (2007) 2.21
The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease. J Exp Med (2007) 2.16
Fibrin(ogen) mediates acute inflammatory responses to biomaterials. J Exp Med (1993) 2.09
The basement membrane/basal lamina of skeletal muscle. J Biol Chem (2003) 2.07
Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med (2003) 1.99
Helper (CD4(+)) and cytotoxic (CD8(+)) T cells promote the pathology of dystrophin-deficient muscle. Clin Immunol (2001) 1.94
Regulation and dysregulation of fibrosis in skeletal muscle. Exp Cell Res (2010) 1.79
Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB J (2007) 1.76
Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway. Genes Dev (2008) 1.73
Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy. Proc Natl Acad Sci U S A (2006) 1.69
Reduced necrosis of dystrophic muscle by depletion of host neutrophils, or blocking TNFalpha function with Etanercept in mdx mice. Neuromuscul Disord (2006) 1.57
Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis. Proc Natl Acad Sci U S A (2004) 1.54
Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. J Clin Invest (2007) 1.52
Vascular endothelial growth factor modulates skeletal myoblast function. Am J Pathol (2003) 1.50
Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease. Curr Top Dev Biol (2011) 1.47
Identification of a novel recognition sequence for integrin alphaM beta2 within the gamma-chain of fibrinogen. J Biol Chem (1998) 1.47
Anti-TNFalpha (Remicade) therapy protects dystrophic skeletal muscle from necrosis. FASEB J (2004) 1.44
PlGF-MMP-9-expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle. Nat Med (2008) 1.38
Interactions between neutrophils and macrophages promote macrophage killing of rat muscle cells in vitro. J Physiol (2002) 1.31
Fibrinogen activates NF-kappa B transcription factors in mononuclear phagocytes. J Immunol (1998) 1.28
Neutrophils contribute to muscle injury and impair its resolution after lengthening contractions in mice. J Physiol (2004) 1.28
Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization. Proc Natl Acad Sci U S A (2010) 1.28
Mechanical signal transduction in skeletal muscle growth and adaptation. J Appl Physiol (1985) (2005) 1.28
The role of tumor necrosis factor-alpha (TNF-alpha) in skeletal muscle regeneration. Studies in TNF-alpha(-/-) and TNF-alpha(-/-)/LT-alpha(-/-) mice. J Histochem Cytochem (2001) 1.27
Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo. Blood (2001) 1.25
Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle. Am J Physiol Cell Physiol (2005) 1.24
Recognition of fibrinogen by leukocyte integrins. Ann N Y Acad Sci (2001) 1.22
Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen. Cancer Res (2010) 1.21
Fibrin(ogen)-alpha M beta 2 interactions regulate leukocyte function and innate immunity in vivo. Exp Biol Med (Maywood) (2004) 1.20
Fibrinogen signal transduction in the nervous system. J Thromb Haemost (2009) 1.17
The incorporation of fibrinogen into extracellular matrix is dependent on active assembly of a fibronectin matrix. J Cell Sci (2002) 1.17
Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo. Blood (2002) 1.10
Reduced muscle necrosis and long-term benefits in dystrophic mdx mice after cV1q (blockade of TNF) treatment. Neuromuscul Disord (2008) 1.09
Matrix-fibrinogen enhances wound closure by increasing both cell proliferation and migration. Blood (2003) 1.08
Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention. Int Rev Immunol (2008) 1.07
Fibrinogen-CD11b/CD18 interaction activates the NF-kappa B pathway and delays apoptosis in human neutrophils. Eur J Immunol (2003) 1.07
AlphaV integrins play an important role in myofibroblast differentiation. Wound Repair Regen (2004) 1.06
Neutrophils injure cultured skeletal myotubes. Am J Physiol Cell Physiol (2001) 1.05
Effect of systemic fibrinogen depletion on intraabdominal abscess formation. J Lab Clin Med (1991) 1.02
Sequence gamma 377-395(P2), but not gamma 190-202(P1), is the binding site for the alpha MI-domain of integrin alpha M beta 2 in the gamma C-domain of fibrinogen. Biochemistry (2003) 1.01
The effects of ancrod, the coagulating enzyme from the venom of Malayan pit viper (A. rhodostoma) on prothrombin and fibrinogen metabolism and fibrinopeptide A release in man. J Lab Clin Med (1978) 0.96
Beta3-integrin mediates satellite cell differentiation in regenerating mouse muscle. FASEB J (2011) 0.93
Administration of the non-steroidal anti-inflammatory drug ibuprofen increases macrophage concentrations but reduces necrosis during modified muscle use. Inflamm Res (2003) 0.87
Alpha v beta 3 and alpha v beta 5 integrins and their role in muscle precursor cell adhesion. Biol Cell (2008) 0.79
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18
Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells. Blood (2004) 3.13
Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab (2008) 3.00
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo. J Clin Invest (2004) 2.57
A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification. Proc Natl Acad Sci U S A (2002) 2.53
Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends Cell Biol (2005) 2.23
Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J (2007) 2.21
The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease. J Exp Med (2007) 2.16
The thrombomodulin-protein C system is essential for the maintenance of pregnancy. Nat Med (2003) 1.98
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation. Nat Commun (2012) 1.82
Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage. J Neurosci (2010) 1.82
Regulation and dysregulation of fibrosis in skeletal muscle. Exp Cell Res (2010) 1.79
Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression. Blood (2009) 1.79
E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription. EMBO J (2005) 1.76
Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway. Genes Dev (2008) 1.73
The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A. Blood (2011) 1.71
Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis. Kidney Int (2011) 1.70
Plasmin generation dependent on alpha-enolase-type plasminogen receptor is required for myogenesis. Thromb Haemost (2003) 1.65
Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice. Cancer Res (2002) 1.64
NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching. Proc Natl Acad Sci U S A (2004) 1.56
Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. J Clin Invest (2007) 1.52
Training depletes muscle glutathione in patients with chronic obstructive pulmonary disease and low body mass index. Respiration (2006) 1.47
Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease. Curr Top Dev Biol (2011) 1.47
p38 MAPK-induced nuclear factor-kappaB activity is required for skeletal muscle differentiation: role of interleukin-6. Mol Biol Cell (2004) 1.44
p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair. J Cell Biol (2011) 1.43
Macrophage plasticity and the role of inflammation in skeletal muscle repair. Mediators Inflamm (2013) 1.40
Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword? FEBS J (2013) 1.33
Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals. J Am Soc Nephrol (2007) 1.25
Epigenetic regulation of myogenesis. Epigenetics (2009) 1.23
uPA deficiency exacerbates muscular dystrophy in MDX mice. J Cell Biol (2007) 1.22
Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen. Cancer Res (2010) 1.21
Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells. FEBS J (2013) 1.21
Fibrin(ogen)-alpha M beta 2 interactions regulate leukocyte function and innate immunity in vivo. Exp Biol Med (Maywood) (2004) 1.20
Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload. Blood (2011) 1.20
Factor XIII activity mediates red blood cell retention in venous thrombi. J Clin Invest (2014) 1.18
Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets. Blood (2003) 1.18
PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy. J Cell Biol (2012) 1.18
TAR DNA-Binding protein 43 accumulation in protein aggregate myopathies. J Neuropathol Exp Neurol (2009) 1.15
Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo. Blood (2010) 1.12
Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain. Blood (2008) 1.11
Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo. Blood (2002) 1.10
Reduced thrombin generation increases host susceptibility to group A streptococcal infection. Blood (2008) 1.10
Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases. Cell Cycle (2008) 1.04
Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia. Blood (2013) 1.03
Genetic deficiency of p38alpha reveals its critical role in myoblast cell cycle exit: the p38alpha-JNK connection. Cell Cycle (2007) 1.01
Deleterious effects of plasminogen activators in neonatal cerebral hypoxia-ischemia. Am J Pathol (2008) 1.01
Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain. Blood (2011) 1.00
Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence. J Biol Chem (2011) 0.99
Plasminogen supports tumor growth through a fibrinogen-dependent mechanism linked to vascular patency. Blood (2003) 0.97
Control of thrombus embolization and fibronectin internalization by integrin alpha IIb beta 3 engagement of the fibrinogen gamma chain. Blood (2003) 0.97
Transcriptional and posttranscriptional regulation of the plasminogen activator system. Thromb Haemost (2005) 0.95
Fibrin but not adsorbed fibrinogen supports fibronectin assembly by spread platelets. Effects of the interaction of alphaIIb beta3 with the C terminus of the fibrinogen gamma-chain. J Biol Chem (2005) 0.93
Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes. EMBO J (2004) 0.93
Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding. Eur J Biochem (2003) 0.92
Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification. J Clin Invest (2015) 0.91
Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor. BMC Gastroenterol (2006) 0.91
Plasminogen directs the pleiotropic effects of uPA in liver injury and repair. Am J Physiol Gastrointest Liver Physiol (2002) 0.90
Administration of factor XIII B subunit increased plasma factor XIII A subunit levels in factor XIII B subunit knock-out mice. Int J Hematol (2007) 0.90
The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1). Front Biosci (2005) 0.90
Fibrin(ogen)-independent role of plasminogen activators in acetaminophen-induced liver injury. Am J Pathol (2012) 0.89
Mechanisms coupling the hemostatic system to colitis-associated cancer. Thromb Res (2010) 0.89
Mechanisms linking tumor cell-associated procoagulant function to tumor metastasis. Thromb Res (2007) 0.89
Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair. J Biol Chem (2009) 0.88
Plasmin deficiency does not alter endogenous murine amyloid beta levels in mice. Neurosci Lett (2004) 0.88
Differential regulation of the muscle-specific GLUT4 enhancer in regenerating and adult skeletal muscle. J Biol Chem (2003) 0.87
Early detection of thrombin activity in neuroinflammatory disease. Ann Neurol (2014) 0.87
MKP-1 coordinates ordered macrophage-phenotype transitions essential for stem cell-dependent tissue repair. Cell Cycle (2012) 0.86
Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes. J Clin Invest (2014) 0.86
Geroconversion of aged muscle stem cells under regenerative pressure. Cell Cycle (2014) 0.86