Published in Nucleic Acids Res on July 11, 1989
The influence of the 2-amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA. EMBO J (1995) 0.99
Uranyl photoprobing of a four-way DNA junction: evidence for specific metal ion binding. EMBO J (1994) 0.98
Uranyl photofootprinting of triple helical DNA. Nucleic Acids Res (1992) 0.92
Effects of diaminopurine and inosine substitutions on A-tract induced DNA curvature. Importance of the 3'-A-tract junction. Nucleic Acids Res (1997) 0.85
Metal ion as both a cofactor and a probe of metal-binding sites in a uranyl-specific DNAzyme: a uranyl photocleavage study. Nucleic Acids Res (2013) 0.79
Topography of lacUV5 initiation complexes. Nucleic Acids Res (2001) 0.77
A new trinuclear complex of platinum and iron efficiently promotes cleavage of plasmid DNA. Nucleic Acids Res (1993) 0.75
Compilation and analysis of Escherichia coli promoter DNA sequences. Nucleic Acids Res (1983) 38.72
E. coli RNA polymerase interacts homologously with two different promoters. Cell (1980) 19.71
A procedure for the rapid, large-scall purification of Escherichia coli DNA-dependent RNA polymerase involving Polymin P precipitation and DNA-cellulose chromatography. Biochemistry (1975) 16.43
Pyrimidine-specific chemical reactions useful for DNA sequencing. Nucleic Acids Res (1980) 9.12
The operator-binding domain of lambda repressor: structure and DNA recognition. Nature (1982) 6.03
Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein. Proc Natl Acad Sci U S A (1986) 5.97
Structure of the lambda complex at 2.5 A resolution: details of the repressor-operator interactions. Science (1988) 4.67
RNA polymerase unwinds an 11-base pair segment of a phage T7 promoter. Nature (1979) 4.63
The regulation of transcription initiation in bacteria. Annu Rev Genet (1985) 4.15
DNA supercoiling promotes formation of a bent repression loop in lac DNA. J Mol Biol (1987) 3.81
A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes. Cell (1982) 3.58
Bacteriophage lambda repressor and cro protein: interactions with operator DNA. Methods Enzymol (1980) 3.52
The MerR heavy metal receptor mediates positive activation in a topologically novel transcription complex. Cell (1989) 3.18
Energetic coupling between DNA bending and base pair opening. Proc Natl Acad Sci U S A (1988) 2.84
Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes. Proc Natl Acad Sci U S A (1983) 2.41
The molecular topography of RNA polymerase-promoter interaction. Cell (1979) 2.31
The structure of tandem regulatory regions in the deo operon of Escherichia coli K12. EMBO J (1982) 2.28
Organization of the murine Ig-related lambda 5 gene transcribed selectively in pre-B lymphocytes. EMBO J (1987) 1.97
Topological unwinding of strong and weak promoters by RNA polymerase. A comparison between the lac wild-type and the UV5 sites of Escherichia coli. J Mol Biol (1987) 1.85
Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase. Biochemistry (1985) 1.69
Structure and function of E. coli promoter DNA. CRC Crit Rev Biochem (1987) 1.42
DNA-dependent RNA polymerase of Escherichia coli induces bending or an increased flexibility of DNA by specific complex formation. EMBO J (1988) 1.40
The effects of covalent additions of a psoralen on transcription by E. coli RNA polymerase. Nucleic Acids Res (1987) 1.39
Interaction of Escherichia coli RNA polymerase with DNA in an elongation complex arrested at a specific psoralen crosslink site. J Mol Biol (1988) 1.37
Topography of interaction of Escherichia coli RNA polymerase subunits with lac UV5 promoter. FEBS Lett (1981) 1.27
Detection of intercalation-induced changes in DNA structure by reaction with diethyl pyrocarbonate or potassium permanganate. Evidence against the induction of Hoogsteen base pairing by echinomycin. FEBS Lett (1988) 1.10
Uranyl salts as photochemical agents for cleavage of DNA and probing of protein-DNA contacts. FEBS Lett (1988) 1.04
Spatial arrangement of DNA-dependent RNA polymerase of Escherichia coli and DNA in the specific complex. A neutron small angle scattering study. J Mol Biol (1988) 1.03
A description of conformational transitions in the Pribnow box of the trp promoter of Escherichia coli. Biochemistry (1988) 0.89
Photocleavage of DNA and photofootprinting of E. coli RNA polymerase bound to promoter DNA by azido-9-acridinylamines. Nucleic Acids Res (1988) 0.86
Psoralen photofootprinting of protein-binding sites on DNA. FEBS Lett (1988) 0.84
A specific and efficient photoreaction between E. coli RNA polymerase and T+1 in the lacUV5 or deoP1 promoter. Nucleic Acids Res (1988) 0.80
Shortening of Right Humerus and Left Thigh due to Unobserved Fractures in Early Life (Infantile Scurvy?). Proc R Soc Med (1910) 0.77
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature (1993) 8.83
Solid-phase synthesis of peptide nucleic acids. J Pept Sci (1997) 2.67
Stability of peptide nucleic acids in human serum and cellular extracts. Biochem Pharmacol (1994) 2.60
Identification and characterization of genomic nucleosome-positioning sequences. J Mol Biol (1997) 2.41
Single base pair mutation analysis by PNA directed PCR clamping. Nucleic Acids Res (1993) 2.20
Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA. Nucleic Acids Res (1995) 2.07
Bactericidal antisense effects of peptide-PNA conjugates. Nat Biotechnol (2001) 1.96
24-h ambulatory blood pressure in 352 normal Danish subjects, related to age and gender. Am J Hypertens (1995) 1.94
DNA-like double helix formed by peptide nucleic acid. Nature (1994) 1.87
Template switching between PNA and RNA oligonucleotides. Nature (1995) 1.84
DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA. Proc Natl Acad Sci U S A (1993) 1.80
Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA. Proc Natl Acad Sci U S A (1999) 1.74
Antisense properties of duplex- and triplex-forming PNAs. Nucleic Acids Res (1996) 1.63
Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique. Biochemistry (1997) 1.59
Peptide nucleic acids (PNA): synthesis, properties and potential applications. Bioorg Med Chem (1996) 1.58
Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA. Nucleic Acids Res (1998) 1.53
Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA. Proc Natl Acad Sci U S A (1995) 1.51
Solution structure of a peptide nucleic acid-DNA duplex. Nat Struct Biol (1996) 1.48
Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nat Biotechnol (1998) 1.46
Sequence selective double strand DNA cleavage by peptide nucleic acid (PNA) targeting using nuclease S1. Nucleic Acids Res (1993) 1.46
Thermodynamics of sequence-specific binding of PNA to DNA. Biochemistry (2000) 1.46
The incidence rate of phaeochromocytoma and Conn's syndrome in Denmark, 1977-1981. J Hum Hypertens (1988) 1.45
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters. Proc Natl Acad Sci U S A (1994) 1.42
Enhanced peptide nucleic acid binding to supercoiled DNA: possible implications for DNA "breathing" dynamics. Biochemistry (1996) 1.39
PD-loop: a complex of duplex DNA with an oligonucleotide. Proc Natl Acad Sci U S A (1998) 1.35
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution. Nat Struct Biol (1997) 1.35
Increased DNA binding and sequence discrimination of PNA oligomers containing 2,6-diaminopurine. Nucleic Acids Res (1997) 1.25
Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA. Proc Natl Acad Sci U S A (1998) 1.23
Effect of secondary structure on the thermodynamics and kinetics of PNA hybridization to DNA hairpins. J Am Chem Soc (2001) 1.21
Mismatch-sensitive hybridization detection by peptide nucleic acids immobilized on a quartz crystal microbalance. Anal Chem (1997) 1.20
Accuracy of auscultatory blood pressure measurements in hypertensive and obese subjects. Hypertension (1983) 1.17
Hybridization of peptide nucleic acid. Biochemistry (1998) 1.16
A highly fluorescent DNA base analogue that forms Watson-Crick base pairs with guanine. J Am Chem Soc (2001) 1.13
A formula for thermal stability (Tm) prediction of PNA/DNA duplexes. Nucleic Acids Res (1998) 1.11
Peptide nucleic acids and their potential applications in biotechnology. Trends Biotechnol (1993) 1.10
Detection of intercalation-induced changes in DNA structure by reaction with diethyl pyrocarbonate or potassium permanganate. Evidence against the induction of Hoogsteen base pairing by echinomycin. FEBS Lett (1988) 1.10
Antisense properties of peptide nucleic acid. Biochim Biophys Acta (1999) 1.10
Quinoxaline antibiotics enhance peptide nucleic acid binding to double-stranded DNA. Biochemistry (2000) 1.09
Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: sequence-specific suicide transcription. Nucleic Acids Res (1996) 1.09
An experimental study of mechanism and specificity of peptide nucleic acid (PNA) binding to duplex DNA. J Mol Biol (1999) 1.09
Site specificity of psoralen-DNA interstrand cross-linking determined by nuclease Bal31 digestion. Biochemistry (1986) 1.08
[Smoking during pregnancy]. Ugeskr Laeger (1994) 1.08
Screening for genetic mutations. Nature (1996) 1.08
Progress in developing PNA as a gene-targeted drug. Antisense Nucleic Acid Drug Dev (1997) 1.07
Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer. Microbiology (2000) 1.07
Smoking related to 24-h ambulatory blood pressure and heart rate: a study in 352 normotensive Danish subjects. Am J Hypertens (1997) 1.05
Sequence-specific protection of duplex DNA against restriction and methylation enzymes by pseudocomplementary PNAs. Biochemistry (2000) 1.05
PNA as a rare genome-cutter. Nature (1996) 1.04
Electron microscopy mapping of oligopurine tracts in duplex DNA by peptide nucleic acid targeting. Nucleic Acids Res (1994) 1.04
Plant crops as a source of fuel and hydrocarbon-like materials. Science (1977) 1.04
Auscultatory measurement of blood pressure performed by the doctor on duty. Acta Med Scand (1975) 1.01
Oblique views in lung perfusion scanning: clinical utility and limitations. J Nucl Med (1977) 0.99
The influence of the 2-amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA. EMBO J (1995) 0.99
[Changes in the smoking habits of Danes in the period 1970-1987]. Ugeskr Laeger (1988) 0.99
The accuracy of auscultatory measurement of arm blood pressure in very obese subjects. Acta Med Scand (1974) 0.98
Uranyl photoprobing of a four-way DNA junction: evidence for specific metal ion binding. EMBO J (1994) 0.98
Structural characterization of PNA-DNA duplexes by NMR. Evidence for DNA in a B-like conformation. Biochemistry (1994) 0.98
Sequence-specific purification of nucleic acids by PNA-controlled hybrid selection. Biotechniques (1995) 0.97
Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation. J Mol Biol (1999) 0.97
PNA-nucleic acid complexes. Structure, stability and dynamics. Q Rev Biophys (1996) 0.95
Analysis of various sequence-specific triplexes by electron and atomic force microscopies. Biophys J (1998) 0.95
Strain gauge studies of distal blood pressure in normal subjects and in patients with peripheral arterial disease. Analysis of normal variation and reproducibility and comparison to intraarterial measurements. Scand J Clin Lab Invest Suppl (1973) 0.95
Structural isomers of bis-PNA bound to a target in duplex DNA. J Mol Biol (2001) 0.95
In vitro transcription and translation inhibition by anti-promyelocytic leukemia (PML)/retinoic acid receptor alpha and anti-PML peptide nucleic acid. Blood (1996) 0.94
Investigating the kinetics of DNA-DNA and PNA-DNA interactions using surface plasmon resonance-enhanced fluorescence spectroscopy. Biosens Bioelectron (2001) 0.93
[Consumption of tobacco in Denmark in the period 1920-1975]. Ugeskr Laeger (1976) 0.93
Photofootprinting of drug-binding sites on DNA using diazo- and azido-9-aminoacridine derivatives. Eur J Biochem (1989) 0.93
Reinterpretation of linear dichroism of chromatin supports a perpendicular linker orientation in the folded state. J Biomol Struct Dyn (1990) 0.92
Information transfer from peptide nucleic acids to RNA by template-directed syntheses. Nucleic Acids Res (1997) 0.92
Acridine-psoralen amines and their interaction with deoxyribonucleic acid. Biochemistry (1983) 0.92
Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA. Nucleic Acids Res (1997) 0.91
Cellular uptake of adamantyl conjugated peptide nucleic acids. Bioconjug Chem (2000) 0.91
Effect of labetalol on plasma noradrenaline and adrenaline in hypertensive man. Eur J Clin Pharmacol (1978) 0.90
Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription. Nucleic Acids Res (1998) 0.90
Characterization of promoter recognition complexes formed by CRP and CytR for repression and by CRP and RNA polymerase for activation of transcription on the Escherichia coli deoP2 promoter. J Biol Chem (1993) 0.90
Measurements of systolic pressure in the limbs of patients with arterial occlusive disease. Surg Gynecol Obstet (1973) 0.89
Information transfer from DNA to peptide nucleic acids by template-directed syntheses. Nucleic Acids Res (1997) 0.89
[Changes in Danish smoking habits 1958-1976]. Ugeskr Laeger (1978) 0.89
DNA binding and cleavage by a cationic manganese porphyrin-peptide nucleic acid conjugate. Bioconjug Chem (1997) 0.88
Acute and long-term effects of labetalol on systemic and pulmonary haemodynamics in hypertensive patients. Eur J Clin Pharmacol (1980) 0.88
Photoaffinity labeling of chromatin. Synthesis and properties of arylazido derivatives of 9-aminoacridine: potential photolabels for chromatin studies. Eur J Biochem (1982) 0.88
Formation of oligonucleotide-PNA-chimeras by template-directed ligation. J Am Chem Soc (1998) 0.87
Sensitive quantitation of endotoxin by enzyme-linked immunosorbent assay with monoclonal antibody against Limulus peptide C. J Clin Microbiol (1994) 0.87
Fluorescein-conjugated lysine monomers for solid phase synthesis of fluorescent peptides and PNA oligomers. Bioconjug Chem (1997) 0.86
A comparative study of atenolol and metoprolol in the treatment of hypertension. Br J Clin Pharmacol (1981) 0.86
Intra-arterial infusion of prostaglandin E1 in normal subjects and patients with peripheral arterial disease. Scand J Clin Lab Invest (1976) 0.86
Psoralenamines. 3. Synthesis, pharmacological behavior, and DNA binding of 5-(aminomethyl)-8-methoxy-, 5-[[(3-aminopropyl)oxy]methyl]-, and 8-[(3-aminopropyl)oxy]psoralen derivatives. J Med Chem (1985) 0.86
Photocleavage of DNA and photofootprinting of E. coli RNA polymerase bound to promoter DNA by azido-9-acridinylamines. Nucleic Acids Res (1988) 0.86
In vitro transcriptional and translational block of the bcl-2 gene operated by peptide nucleic acid. Biochem Biophys Res Commun (1999) 0.86
Phospholipid membrane permeability of peptide nucleic acid. FEBS Lett (1995) 0.86
Effects of diaminopurine and inosine substitutions on A-tract induced DNA curvature. Importance of the 3'-A-tract junction. Nucleic Acids Res (1997) 0.85
Peptide nucleic acids directed to the promoter of the alpha-chain of the interleukin-2 receptor. Biochim Biophys Acta (1996) 0.84
Enantiomeric cross-inhibition in the synthesis of oligonucleotides on a nonchiral template. J Am Chem Soc (1997) 0.84
Psoralen photofootprinting of protein-binding sites on DNA. FEBS Lett (1988) 0.84
Effect of temperature and ionic strength on the dissociation kinetics and lifetime of PNA-DNA triplexes. Biochemistry (2000) 0.84
The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals. J Biomol Struct Dyn (2004) 0.84
Enhanced uranyl photocleavage across the minor groove of all (A/T)4 sequences indicates a similar narrow minor groove conformation. J Mol Recognit (1997) 0.84
Distal blood pressure measurement in occlusive arterial disease, strain gauge compared to xenon-133. Angiology (1972) 0.83