Published in Biomed Res Int on June 18, 2014
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Integrative analysis of signaling pathways and diseases associated with the miR-106b/25 cluster and their function study in berberine-induced multiple myeloma cells. Funct Integr Genomics (2016) 0.76
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Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism. J Cell Biochem (2010) 1.42
Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death. Int J Radiat Oncol Biol Phys (2008) 1.29
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Conversation between apoptosis and autophagy: "Is it your turn or mine?". Apoptosis (2011) 1.24
p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo. Mol Carcinog (2009) 1.21
Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. Biochem Pharmacol (2011) 1.17
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Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. PLoS One (2012) 1.12
Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis. Anticancer Res (2009) 1.07
Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage. Mutat Res (2008) 1.04
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Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth. PLoS One (2013) 1.02
Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells. Int J Oncol (2009) 1.02
Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells. Mutat Res (2012) 1.00
The cytoplasmic side of p53's oncosuppressive activities. FEBS Lett (2014) 0.97
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Berberine inhibits growth and induces G1 arrest and apoptosis in human cholangiocarcinoma QBC939 cells. J Pharmacol Sci (2012) 0.93
Synthesis and cytotoxicity evaluation of 13-n-alkyl berberine and palmatine analogues as anticancer agents. Molecules (2012) 0.92
Comprehensive study in the inhibitory effect of berberine on gene transcription, including TATA box. PLoS One (2011) 0.92
Berberine sensitizes TRAIL-induced apoptosis through proteasome-mediated downregulation of c-FLIP and Mcl-1 proteins. Int J Oncol (2010) 0.92
Berberine induces cell death in human hepatoma cells in vitro by downregulating CD147. Cancer Sci (2011) 0.92
Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF-κB pathway. Cancer Sci (2012) 0.92
The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells. Eur J Pharmacol (2012) 0.91
Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells. Oncol Rep (2013) 0.89
Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma. Mol Med Rep (2013) 0.87
Assessment of berberine as a multi-target antimicrobial: a multi-omics study for drug discovery and repositioning. OMICS (2013) 0.87
Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions. Biochem Pharmacol (2013) 0.85
RNA targeting by small molecules: Binding of protoberberine, benzophenanthridine and aristolochia alkaloids to various RNA structures. J Biosci (2012) 0.84
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Study of the effects of a new pyrazolecarboxamide: changes in mitochondria and induction of apoptosis. Int J Biochem Cell Biol (2009) 0.82
Alkaloids in the nature: pharmacological applications in clinical practice of berberine and mate tea. Curr Top Med Chem (2014) 0.82
Radiosensitization effects of berberine on human breast cancer cells. Int J Mol Med (2012) 0.81
Apoptosis-prone phenotype of human colon carcinoma cells with a high level amplification of the c-myc gene. Oncogene (1999) 0.81
Berberine represses DAXX gene transcription and induces cancer cell apoptosis. Lab Invest (2013) 0.81
Biophysical studies on the effect of the 13 position substitution of the anticancer alkaloid berberine on its DNA binding. J Phys Chem B (2012) 0.80
Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells. Int J Oncol (2013) 0.80
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Synthesis and anticancer activity of a novel series of 9-O-substituted berberine derivatives: a lipophilic substitute role. Bioorg Med Chem Lett (2012) 0.79
Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins. Cell Cycle (2006) 0.79
Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med (2013) 0.78
Antitumor effect of novel berberine derivatives in breast cancer cells. Biofactors (2013) 0.77
Spectroscopic studies on the binding interaction of novel 13-phenylalkyl analogs of the natural alkaloid berberine to nucleic acid triplexes. Spectrochim Acta A Mol Biomol Spectrosc (2013) 0.77
Interaction of Berberine derivative with protein POT1 affect telomere function in cancer cells. Biochem Biophys Res Commun (2012) 0.77
A new cell-selective three-dimensional microincubator based on silicon photonic crystals. PLoS One (2012) 0.77
Multiple effects of the Na(+)/H (+) antiporter inhibitor HMA on cancer cells. Apoptosis (2013) 0.77
Biophysical characterization of the strong stabilization of the RNA triplex poly(U)•poly(A)*poly(U) by 9-O-(ω-amino) alkyl ether berberine analogs. PLoS One (2012) 0.76
Berberine acts as a natural inhibitor of Wnt/β-catenin signaling--identification of more active 13-arylalkyl derivatives. Biofactors (2013) 0.76