Published in Int J Nanomedicine on August 24, 2011
Amelioration of IFN-γ and TNF-α-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway. PLoS One (2013) 0.95
Molecular mechanisms of action of herbal antifungal alkaloid berberine, in Candida albicans. PLoS One (2014) 0.86
Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis. J Transl Med (2014) 0.82
n-butylidenephthalide protects against dopaminergic neuron degeneration and α-synuclein accumulation in Caenorhabditis elegans models of Parkinson's disease. PLoS One (2014) 0.82
Development and evaluation of vitamin E d-α-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical. Int J Nanomedicine (2016) 0.82
Multiple effects of berberine derivatives on colon cancer cells. Biomed Res Int (2014) 0.81
Testing the nanoparticle-allostatic cross-adaptation-sensitization model for homeopathic remedy effects. Homeopathy (2013) 0.81
Plant natural products as an anti-lipid droplets accumulation agent. J Nat Med (2014) 0.80
Role of Berberine in the Treatment of Methicillin-Resistant Staphylococcus aureus Infections. Sci Rep (2016) 0.80
Berberine Antifungal Activity in Fluconazole-Resistant Pathogenic Yeasts: Action Mechanism Evaluated by Flow Cytometry and Biofilm Growth Inhibition in Candida spp. Antimicrob Agents Chemother (2016) 0.79
Homeopathic medications as clinical alternatives for symptomatic care of acute otitis media and upper respiratory infections in children. Glob Adv Health Med (2013) 0.79
Biophysical characterization of the strong stabilization of the RNA triplex poly(U)•poly(A)*poly(U) by 9-O-(ω-amino) alkyl ether berberine analogs. PLoS One (2012) 0.76
Review of tumor dormancy therapy using traditional oriental herbal medicine. J Pharmacopuncture (2013) 0.75
Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner. PLoS One (2015) 0.75
From prejudice to evidence: the case of rhizoma coptidis in singapore. Evid Based Complement Alternat Med (2014) 0.75
Chinese Herbs Interfering with Cancer Reprogramming Metabolism. Evid Based Complement Alternat Med (2016) 0.75
Autologous fat transplantation in patients with breast cancer: "silencing" or "fueling" cancer recurrence? Breast (2011) 1.80
Berberine reduces insulin resistance induced by dexamethasone in theca cells in vitro. Fertil Steril (2010) 1.49
Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism. J Cell Biochem (2010) 1.42
Angiogenesis, adipokines and breast cancer. Cytokine Growth Factor Rev (2009) 1.37
Novel multilayered lipid vesicles: comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles. Biochemistry (1985) 1.37
Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation. Toxicol Appl Pharmacol (2008) 1.36
Synergistic tumor-killing effect of radiation and berberine combined treatment in lung cancer: the contribution of autophagic cell death. Int J Radiat Oncol Biol Phys (2008) 1.29
Micro- and nanocarrier-mediated lung targeting. Expert Opin Drug Deliv (2010) 1.23
Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E₂ and prostaglandin E₂ receptors. Carcinogenesis (2010) 1.23
Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res (2008) 1.22
p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo. Mol Carcinog (2009) 1.21
Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. Arch Toxicol (2007) 1.16
From nanotechnology to nanomedicine: applications to cancer research. Curr Mol Med (2010) 1.15
Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway. Eur J Pharmacol (2010) 1.14
Berberine Moderates Glucose and Lipid Metabolism through Multipathway Mechanism. Evid Based Complement Alternat Med (2010) 1.13
Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells. Cancer Res (2010) 1.10
Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells. Int J Mol Med (2009) 1.09
Peroxisome proliferator-activated receptor-gamma protects ERBB2-positive breast cancer cells from palmitate toxicity. Breast Cancer Res (2009) 1.07
Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis. Anticancer Res (2009) 1.07
Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-κB activation. Eur J Pharmacol (2010) 1.05
Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells. Anticancer Res (2009) 1.04
Anticachectic effects of the natural herb Coptidis rhizoma and berberine on mice bearing colon 26/clone 20 adenocarcinoma. Int J Cancer (2002) 1.02
Obesity and breast cancer: the roles of peroxisome proliferator-activated receptor-γ and plasminogen activator inhibitor-1. PPAR Res (2009) 1.01
Berberine inhibits adipogenesis in high-fat diet-induced obesity mice. Fitoterapia (2009) 1.00
Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. Mediators Inflamm (2010) 0.99
Adipose tissue-derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor-derived factors. Anal Cell Pathol (Amst) (2010) 0.98
Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design. Med Res Rev (2010) 0.97
Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis. PLoS One (2011) 0.96
Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis. Mol Carcinog (2011) 0.94
Anti-cancer role of SPARC, an inhibitor of adipogenesis. Cancer Treat Rev (2011) 0.93
Advance of studies on anti-atherosclerosis mechanism of berberine. Chin J Integr Med (2010) 0.91
Berberine improves free-fatty-acid-induced insulin resistance in L6 myotubes through inhibiting peroxisome proliferator-activated receptor gamma and fatty acid transferase expressions. Metabolism (2009) 0.89
Berberine inhibits WEHI-3 leukemia cells in vivo. In Vivo (2007) 0.88
Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes. Eur J Pharmacol (2010) 0.88
Progress in nanotechnology for healthcare. Minim Invasive Ther Allied Technol (2010) 0.85
Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXRα and PPARα transcriptional programs. Endocr J (2010) 0.85
Berberine induced down-regulation of matrix metalloproteinase-1, -2 and -9 in human gastric cancer cells (SNU-5) in vitro. In Vivo (2008) 0.85
Supramolecular interaction of ethylenediamine linked beta-cyclodextrin dimer and berberine hydrochloride by spectrofluorimetry and its analytical application. Talanta (2007) 0.83
Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation. Int J Mol Med (2009) 0.83
Enhancement of adipogenesis induction by conditioned media obtained from cancer cells. Cancer Lett (2008) 0.83
Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer. J Nucleic Acids (2009) 0.82
Enhancement of Arsenic Trioxide (As(2)O(3))- Mediated Apoptosis Using Berberine in Human Neuroblastoma SH-SY5Y Cells. J Korean Neurosurg Soc (2007) 0.82
Pharmacokinetics and physiologically-based pharmacokinetic modeling of nanoparticles. J Nanosci Nanotechnol (2010) 0.82
Inhibition of DNA topoisomerase I by natural and synthetic mono- and dimeric protoberberine alkaloids. Chem Biodivers (2007) 0.79
[Advances of the mechanism study on berberine in the control of blood glucose and lipid as well as metabolism disorders]. Yao Xue Xue Bao (2010) 0.77
Interaction of anticancer herbal drug berberine with DNA immobilized on the glassy carbon electrode. Bioelectrochemistry (2008) 0.77
Plant DNA barcoding: from gene to genome. Biol Rev Camb Philos Soc (2014) 1.56
A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs. Anticancer Drugs (2009) 1.39
Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities. Am J Chin Med (2011) 1.36
2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res (2010) 1.31
Compatibility art of traditional Chinese medicine: from the perspective of herb pairs. J Ethnopharmacol (2012) 1.29
Biological activities and potential molecular targets of cucurbitacins: a focus on cancer. Anticancer Drugs (2012) 1.25
Fighting fire with fire: poisonous Chinese herbal medicine for cancer therapy. J Ethnopharmacol (2012) 1.22
TNF-alpha, a potent lipid metabolism regulator. Cell Biochem Funct (2009) 1.18
Polymeric micelles drug delivery system in oncology. J Control Release (2012) 1.17
Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. Int J Oncol (2008) 1.15
Chinese herbal medicine-derived compounds for cancer therapy: a focus on hepatocellular carcinoma. J Ethnopharmacol (2013) 1.06
The anticancer properties of Salvia miltiorrhiza Bunge (Danshen): a systematic review. Med Res Rev (2013) 0.97
Adiponectin, an unlocking adipocytokine. Cardiovasc Ther (2009) 0.96
Oridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer cells. Am J Chin Med (2013) 0.95
Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis. Eur J Pharmacol (2011) 0.94
Emodin loaded solid lipid nanoparticles: preparation, characterization and antitumor activity studies. Int J Pharm (2012) 0.94
Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells. Stem Cell Res (2013) 0.93
Corydalis yanhusuo W.T. Wang extract inhibits MCF-7 cell proliferation by inducing cell cycle G2/M arrest. Am J Chin Med (2011) 0.89
Adiponectin: a biomarker for rheumatoid arthritis? Cytokine Growth Factor Rev (2012) 0.89
Allelopathic interactions between the opportunistic species Ulva prolifera and the native macroalga Gracilaria lichvoides. PLoS One (2012) 0.89
Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells. Phytomedicine (2011) 0.89
Is the United States still dominant in the global pharmaceutical innovation network? PLoS One (2013) 0.89
Potential antineoplastic effects of Aloe-emodin: a comprehensive review. Am J Chin Med (2014) 0.89
Phytochemical and pharmacological review of da chuanxiong formula: a famous herb pair composed of chuanxiong rhizoma and gastrodiae rhizoma for headache. Evid Based Complement Alternat Med (2013) 0.88
Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in MCF-7 cells. Am J Chin Med (2012) 0.87
Furanodiene, a natural product, inhibits breast cancer growth both in vitro and in vivo. Cell Physiol Biochem (2012) 0.87
Differential expression of carotenogenic genes, associated changes on astaxanthin production and photosynthesis features induced by JA in H. pluvialis. PLoS One (2012) 0.87
Adiponectin and breast cancer. Med Oncol (2010) 0.87
Simultaneous determination of 11 saponins in Panax notoginseng using HPLC-ELSD and pressurized liquid extraction. J Sep Sci (2006) 0.87
Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells. Am J Chin Med (2013) 0.87
[Preparation, characterization and content determination of cubic phase gel containing capsaicin]. Zhongguo Zhong Yao Za Zhi (2010) 0.86
Recent advances in breast cancer metastasis suppressor 1. Int J Biol Markers (2011) 0.85
Treatment with Z-ligustilide, a component of Angelica sinensis, reduces brain injury after a subarachnoid hemorrhage in rats. J Pharmacol Exp Ther (2011) 0.85
No protective effect of curcumin on hydrogen peroxide-induced cytotoxicity in HepG2 cells. Pharmacol Rep (2011) 0.85
mPEG-b-PCL/TPGS mixed micelles for delivery of resveratrol in overcoming resistant breast cancer. Expert Opin Drug Deliv (2014) 0.84
Research and development of anti-Alzheimer's drugs: an analysis based on technology flows measured by patent citations. Expert Opin Ther Pat (2014) 0.83
Induction of salicylic acid (SA) on transcriptional expression of eight carotenoid genes and astaxanthin accumulation in Haematococcus pluvialis. Enzyme Microb Technol (2012) 0.83
Analysis of Pogostemon cablin from pharmaceutical research to market performances. Expert Opin Investig Drugs (2012) 0.83
Antidiabetic effect of the total polyphenolic acids fraction from Salvia miltiorrhiza Bunge in diabetic rats. Phytother Res (2011) 0.83
Saponins of Panax notoginseng: chemistry, cellular targets and therapeutic opportunities in cardiovascular diseases. Expert Opin Investig Drugs (2014) 0.83
Development of amphotericin B-loaded cubosomes through the SolEmuls technology for enhancing the oral bioavailability. AAPS PharmSciTech (2012) 0.82
Evaluation of putative internal reference genes for gene expression normalization in Nannochloropsis sp. by quantitative real-time RT-PCR. Biochem Biophys Res Commun (2012) 0.82
Complete mitochondrial genome of the sea slug, Placida sp., contains unusual noncoding regions. Mitochondrial DNA (2013) 0.82
Motoneuron differentiation of induced pluripotent stem cells from SOD1G93A mice. PLoS One (2013) 0.82
Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells. Toxicol In Vitro (2012) 0.81
Chemical components, pharmacological properties, and nanoparticulate delivery systems of Brucea javanica. Int J Nanomedicine (2013) 0.81
Structure-based discovery of an immunomodulatory inhibitor of TLR1-TLR2 heterodimerization from a natural product-like database. Chem Commun (Camb) (2015) 0.81
Epigallocatechin-3-gallate potentiates the effect of curcumin in inducing growth inhibition and apoptosis of resistant breast cancer cells. Am J Chin Med (2014) 0.81
Complete chloroplast genome sequence of Magnolia grandiflora and comparative analysis with related species. Sci China Life Sci (2013) 0.81
Tumor pH(e)-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocellular carcinoma treatment. Nanoscale (2015) 0.80
Temperature regulates fatty acid desaturases at a transcriptional level and modulates the fatty acid profile in the Antarctic microalga Chlamydomonas sp. ICE-L. Bioresour Technol (2013) 0.80
Phytantriol-based inverted type bicontinuous cubic phase for vascular embolization and drug sustained release. Eur J Pharm Sci (2010) 0.80
Ganoderma lucidum extract induces G1 cell cycle arrest, and apoptosis in human breast cancer cells. Am J Chin Med (2012) 0.79
Non-ionic surfactant vesicles simultaneously enhance antitumor activity and reduce the toxicity of cantharidin. Int J Nanomedicine (2013) 0.79
Berberine interfered with breast cancer cells metabolism, balancing energy homeostasis. Anticancer Agents Med Chem (2015) 0.79
Two natural glucomannan polymers, from Konjac and Bletilla, as bioactive materials for pharmaceutical applications. Biotechnol Lett (2014) 0.79
Molecular modeling-based inclusion mechanism and stability studies of doxycycline and hydroxypropyl-β-cyclodextrin complex for ophthalmic delivery. AAPS PharmSciTech (2012) 0.79
The Hv-SGT1 gene from Haynaldia villosa contributes to resistances towards both biotrophic and hemi-biotrophic pathogens in common wheat (Triticum aestivum L.). PLoS One (2013) 0.78
Anti-Lung-Cancer Activity and Liposome-Based Delivery Systems of β-Elemene. Evid Based Complement Alternat Med (2012) 0.78
Novel compaction techniques with pellet-containing granules. Eur J Pharm Biopharm (2010) 0.78
Development and characterisation of ursolic acid nanocrystals without stabiliser having improved dissolution rate and in vitro anticancer activity. AAPS PharmSciTech (2014) 0.78
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS. J Pharm Biomed Anal (2013) 0.77
Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy. Expert Opin Drug Deliv (2014) 0.77
Rapid simultaneous determination of isoflavones in Radix puerariae using high-performance liquid chromatography-triple quadrupole mass spectrometry with novel shell-type column. J Sep Sci (2011) 0.77
Synthesis and evaluation of multisubstrate bicyclic pyrimidine nucleoside inhibitors of human thymidine phosphorylase. J Med Chem (2006) 0.77
Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle. Stem Cell Res (2013) 0.77
Enhancing the antitumor activity of berberine hydrochloride by solid lipid nanoparticle encapsulation. AAPS PharmSciTech (2014) 0.77
A generic multiple reaction monitoring based approach for plant flavonoids profiling using a triple quadrupole linear ion trap mass spectrometry. J Am Soc Mass Spectrom (2014) 0.77
Preparation and evaluation of orally disintegrating tablets containing taste-masked microcapsules of berberine hydrochloride. AAPS PharmSciTech (2012) 0.77
Protective effect of schisandrin B against cyclosporine A-induced nephrotoxicity in vitro and in vivo. Am J Chin Med (2012) 0.77
[Chemical constituents from roots of Pueraria lobata]. Zhongguo Zhong Yao Za Zhi (2010) 0.77
A transthylakoid proton gradient and inhibitors induce a non-photochemical fluorescence quenching in unicellular algae Nannochloropsis sp. FEBS Lett (2013) 0.77
Discovery of pentacyclic triterpenoids as potential entry inhibitors of influenza viruses. J Med Chem (2014) 0.77
Synthesis and anti-HCV entry activity studies of β-cyclodextrin-pentacyclic triterpene conjugates. ChemMedChem (2014) 0.76
Aloe-emodin loaded solid lipid nanoparticles: formulation design and in vitro anti-cancer study. Drug Deliv (2014) 0.76
Validating antimetastatic effects of natural products in an engineered microfluidic platform mimicking tumor microenvironment. Mol Pharm (2014) 0.76
[Study on mechanism of ginsenoside Rg1-induced human neural stem cells differentiation by genechip]. Zhongguo Zhong Yao Za Zhi (2012) 0.75
A single molecular probe for multi-analyte (Cr³⁺, Al³⁺ and Fe³⁺) detection in aqueous medium and its biological application. Chem Commun (Camb) (2014) 0.75
Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase. Acta Crystallogr D Biol Crystallogr (2005) 0.75
Stability and aerosolization of pressurized metered dose inhalers containing thymopentin nanoparticles produced using a bottom-up process. Int J Pharm (2012) 0.75
Use of hospital appointment registration systems in China: a survey study. Glob J Health Sci (2013) 0.75
Applications of nanoparticles in herbal medicine: zedoary turmeric oil and its active compound β-elemene. Am J Chin Med (2011) 0.75