Published in Genes Cancer on May 01, 2014
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Class A helix-loop-helix proteins are positive regulators of several cyclin-dependent kinase inhibitors' promoter activity and negatively affect cell growth. Cancer Res (2000) 1.35
Id-1 and Id-2 proteins as molecular markers for human prostate cancer progression. Clin Cancer Res (2004) 1.33
Level of Id-1 protein expression correlates with poor differentiation, enhanced malignant potential, and more aggressive clinical behavior of epithelial ovarian tumors. Clin Cancer Res (2003) 1.32
Id-1, ITF-2, and Id-2 comprise a network of helix-loop-helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis. J Biol Chem (2001) 1.31
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Id2 drives differentiation and suppresses tumor formation in the intestinal epithelium. Cancer Res (2004) 1.26
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Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer. Cancer Sci (2005) 1.05
Regulation of angiogenesis by Id-1 through hypoxia-inducible factor-1alpha-mediated vascular endothelial growth factor up-regulation in hepatocellular carcinoma. Clin Cancer Res (2006) 1.02
Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells. Breast Cancer Res Treat (2010) 1.01
Increased Id-1 expression is significantly associated with poor survival of patients with prostate cancer. Hum Pathol (2007) 1.00
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Overexpression of inhibitor of DNA-binding (ID)-1 protein related to angiogenesis in tumor advancement of ovarian cancers. BMC Cancer (2009) 0.96
Id1/Id3 knockdown inhibits metastatic potential of pancreatic cancer. J Surg Res (2008) 0.94
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Id1 and Id3 co-expression correlates with clinical outcome in stage III-N2 non-small cell lung cancer patients treated with definitive chemoradiotherapy. J Transl Med (2013) 0.91
Id family of transcription factors and vascular lesion formation. Arterioscler Thromb Vasc Biol (2004) 0.90
Expression of Id2 and Id3 mRNA in human lymphocytes. Leuk Res (1995) 0.87
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ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma. BMC Cancer (2013) 0.85
Tumor angiogenesis in mice and men. Cancer Biol Ther (2004) 0.84
Inhibition of tumourigenicity of small cell lung cancer cells by suppressing Id3 expression. Int J Oncol (2010) 0.82
Constitutive overexpression of Id-1 in mammary glands of transgenic mice results in precocious and increased formation of terminal end buds, enhanced alveologenesis, delayed involution. J Cell Physiol (2011) 0.80
Role of inhibitor of DNA binding-1 protein is related to angiogenesis in the tumor advancement of uterine endometrial cancers. Exp Ther Med (2010) 0.78
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ID1 inhibits USF2 and blocks TGF-β-induced apoptosis in mesangial cells. Am J Physiol Renal Physiol (2011) 0.76