P Matthias

Author PubWeight™ 75.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989 22.73
2 A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells. Nature 1988 5.16
3 Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer. EMBO J 1987 4.58
4 OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 1995 3.38
5 Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA). EMBO J 1988 3.33
6 Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells. EMBO J 1990 2.21
7 B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation. Nature 1996 2.10
8 Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2. Nature 1988 1.76
9 Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter. EMBO J 1989 1.70
10 The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1. Mol Cell Biol 1998 1.50
11 Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells. Cell 1982 1.37
12 B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1. Nat Immunol 2001 1.33
13 Isolation and characterization of the rat tryptophan oxygenase gene. EMBO J 1982 1.26
14 Rapid test for in vivo stability and DNA binding of mutated octamer binding proteins with 'mini-extracts' prepared from transfected cells. Nucleic Acids Res 1989 1.16
15 Gene structure and characterization of the murine homologue of the B cell-specific transcriptional coactivator OBF-1. Nucleic Acids Res 1996 1.13
16 The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1. EMBO J 2001 1.13
17 Coactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA. Mol Cell Biol 1998 1.12
18 Extinction of an immunoglobulin kappa promoter in cell hybrids is mediated by the octamer motif and correlates with suppression of Oct-2 expression. Cell 1990 1.12
19 Octamer factors exert a dual effect on the IL-2 and IL-4 promoters. J Immunol 1994 1.09
20 Every enhancer works with every promoter for all the combinations tested: could new regulatory pathways evolve by enhancer shuffling? Gene Expr 1991 1.08
21 Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules. Int Immunol 2000 1.01
22 Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein. Mol Cell Biol 1994 0.98
23 The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction. Immunobiology 1997 0.95
24 Cutting edge: lack of peripheral B cells and severe agammaglobulinemia in mice simultaneously lacking Bruton's tyrosine kinase and the B cell-specific transcriptional coactivator OBF-1. J Immunol 2000 0.91
25 Transcriptional activation and repression, two properties of the lymphoid-specific transcription factor Oct-2a. Eur J Biochem 1995 0.91
26 Involvement of the Ets family factor PU.1 in the activation of immunoglobulin promoters. J Biol Chem 1995 0.91
27 Two closely spaced promoters are equally activated by a remote enhancer: evidence against a scanning model for enhancer action. Nucleic Acids Res 1989 0.86
28 Both immunoglobulin promoter and enhancer sequences are targets for suppression in myeloma-fibroblast hybrid cells. EMBO J 1988 0.85
29 Mapping of the transcriptional repression domain of the lymphoid-specific transcription factor oct-2A. J Biol Chem 1996 0.82
30 Physical state, expression and regulation of two glucocorticoid-controlled genes on bovine papilloma virus vectors. J Mol Biol 1986 0.82
31 Estrogen receptor (ER)-alpha, but not ER-beta, mediates regulation of the insulin-like growth factor I gene by antiestrogens. J Biol Chem 2001 0.80
32 Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization. Genomics 1996 0.80
33 Molecular mechanisms of extinction: old findings and new ideas. Int J Biochem Cell Biol 2000 0.80
34 A factor known to bind to endogenous Ig heavy chain enhancer only in lymphocytes is a ubiquitously active transcription factor. Eur J Biochem 1990 0.79
35 Extinction of immunoglobulin gene expression in B cells upon fusion with HeLa cells is preceded by rapid nuclear depletion of essential transcription factors and is accompanied by widespread inactivation of genes expressed in a B cell-specific manner. J Cell Sci 1997 0.78
36 The lymphoid-specific cofactor OBF-1 is essential for the expression of a V(H) promoter/HS1,2 enhancer-linked transgene in late B cell development. Mol Immunol 2000 0.78
37 Myeloma kappa gene transcription is blocked upon fusion with fibroblasts. Exp Cell Res 1989 0.77
38 The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements. J Biol Chem 1996 0.76
39 A transcriptional terminator between enhancer and promoter does not affect remote transcriptional control. Somat Cell Mol Genet 1990 0.76
40 Steroid controlled expression of the chicken lysozyme and the rat tryptophan oxygenase gene after transfer into eukaryotic cells. J Steroid Biochem 1984 0.75
41 Expression of the chicken lysozyme gene after transfer into homologous and heterologous cells. Prog Clin Biol Res 1982 0.75