Published in EMBO J on July 01, 1989
A compilation of composite regulatory elements affecting gene transcription in vertebrates. Nucleic Acids Res (1995) 4.93
The DNA binding specificity of the bipartite POU domain and its subdomains. EMBO J (1992) 2.36
The putative transposase of transposable element Ac from Zea mays L. interacts with subterminal sequences of Ac. EMBO J (1989) 2.23
The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription. EMBO J (1990) 2.01
A DNA replication enhancer in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1990) 1.98
The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences. Nucleic Acids Res (2000) 1.91
The octamer binding factor Oct6: cDNA cloning and expression in early embryonic cells. Nucleic Acids Res (1990) 1.81
Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression. Mol Cell Biol (1992) 1.78
Segments of the POU domain influence one another's DNA-binding specificity. Mol Cell Biol (1992) 1.77
Transcription factors NFI and NFIII/oct-1 function independently, employing different mechanisms to enhance adenovirus DNA replication. J Virol (1990) 1.72
Statistical analysis of over-represented words in human promoter sequences. Nucleic Acids Res (2004) 1.69
Sequence, expression and mutational analysis of BAF1, a transcriptional activator and ARS1-binding protein of the yeast Saccharomyces cerevisiae. EMBO J (1989) 1.66
Multiple Oct2 isoforms are generated by alternative splicing. Nucleic Acids Res (1991) 1.65
The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins. Mol Cell Biol (1992) 1.59
NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss. Mol Cell Biol (1993) 1.57
Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration. Nucleic Acids Res (1991) 1.46
Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. Nucleic Acids Res (1990) 1.32
The immunoglobulin heavy chain locus contains another B-cell-specific 3' enhancer close to the alpha constant region. Mol Cell Biol (1993) 1.21
The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes. Mol Cell Biol (1990) 1.13
Identification of a novel downstream binding protein implicated in late-phase-specific activation of the adenovirus major late promotor. Nucleic Acids Res (1992) 1.11
Protein-DNA binding: complexities and multi-protein codes. Nucleic Acids Res (2013) 1.09
Delineation of human papillomavirus type 18 enhancer binding proteins: the intracellular distribution of a novel octamer binding protein p92 is cell cycle regulated. Nucleic Acids Res (1991) 1.08
Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation. Mol Cell Biol (1991) 1.07
Oct-2 facilitates functional preinitiation complex assembly and is continuously required at the promoter for multiple rounds of transcription. EMBO J (1993) 1.05
Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors have been highly conserved during vertebrate evolution. Proc Natl Acad Sci U S A (1990) 1.03
Distinct functions of acj6 splice forms in odor receptor gene choice. J Neurosci (2010) 0.99
cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif. Nucleic Acids Res (1993) 0.98
Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors. Mol Cell Biol (1992) 0.93
The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter. Nucleic Acids Res (1994) 0.92
Oct transcription factors in development and stem cells: insights and mechanisms. Development (2013) 0.91
Both Oct-1 and Oct-2A contain domains which can activate the ubiquitously expressed U2 snRNA genes. EMBO J (1991) 0.90
Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoforms. Nucleic Acids Res (1994) 0.89
Specific transcriptional activation in vitro by the herpes simplex virus protein VP16. Nucleic Acids Res (1993) 0.88
The chicken immunoglobulin lambda light chain gene is transcriptionally controlled by a modularly organized enhancer and an octamer-dependent silencer. Nucleic Acids Res (1995) 0.87
POU domain transcription factors from different subclasses stimulate adenovirus DNA replication. Nucleic Acids Res (1992) 0.84
The ubiquitous nuclear protein, NHP1, binds with high affinity to different sequences of the chicken vitellogenin II gene. Nucleic Acids Res (1989) 0.83
Zebrafish pou[c]: a divergent POU family gene ubiquitously expressed during embryogenesis. Nucleic Acids Res (1993) 0.83
The downstream regulatory sequence of the adenovirus type 2 major late promoter is functionally redundant. J Virol (1992) 0.80
Purification and characterization of NF-R1 that regulates the expression of the human multidrug resistance (MDR1) gene. Nucleic Acids Res (1992) 0.77
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell (1983) 20.32
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell (1983) 18.86
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (1986) 14.34
Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells. EMBO J (1983) 10.00
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science (1985) 9.73
Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7. Proc Natl Acad Sci U S A (1980) 9.32
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (1986) 8.64
Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements. Cell (1985) 8.16
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain. Genes Dev (1988) 8.11
Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence. Proc Natl Acad Sci U S A (1984) 7.74
Correct transcription of an immunoglobulin kappa gene requires an upstream fragment containing conserved sequence elements. Nature (1984) 7.66
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes Dev (1987) 5.86
Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation. Cell (1988) 5.18
A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells. Nature (1988) 5.16
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell (1987) 5.04
A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc Natl Acad Sci U S A (1988) 4.72
Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer. EMBO J (1987) 4.58
Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence. Cell (1985) 4.38
Yeast HAP1 activator binds to two upstream activation sites of different sequence. Cell (1987) 4.37
Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences. Nature (1986) 4.21
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. Genes Dev (1988) 4.14
An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity. Nature (1987) 4.11
Regulation of the assembly and expression of variable-region genes. Annu Rev Immunol (1986) 4.09
A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein. Nature (1988) 3.95
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. Proc Natl Acad Sci U S A (1986) 3.81
An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes. Nature (1985) 3.80
OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts. Nucleic Acids Res (1987) 3.56
A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer. Genes Dev (1987) 3.45
Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA). EMBO J (1988) 3.33
Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts. Nature (1986) 3.25
Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev (1988) 3.05
Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif. Science (1988) 3.01
Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA. Mol Cell Biol (1983) 3.00
The POU domain is a bipartite DNA-binding structure. Nature (1988) 2.92
Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Mol Cell Biol (1986) 2.69
A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. Nature (1987) 2.48
Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. EMBO J (1987) 2.46
OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences. Genes Dev (1988) 2.34
A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain. Cell (1988) 2.32
Cell-type preference of immunoglobulin kappa and lambda gene promoters. EMBO J (1985) 2.22
Mutational analysis of the immunoglobulin heavy chain promoter region. Proc Natl Acad Sci U S A (1986) 1.89
Distinct factors with Sp1 and NF-A specificities bind to adjacent functional elements of the human U2 snRNA gene enhancer. Genes Dev (1987) 1.85
Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter. Proc Natl Acad Sci U S A (1987) 1.80
Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2. Nature (1988) 1.76
Promoter and enhancer elements containing a conserved sequence motif are recognized by nuclear factor III, a protein stimulating adenovirus DNA replication. EMBO J (1987) 1.74
The COUP transcription factor binds to an upstream promoter element of the rat insulin II gene. Mol Cell Biol (1988) 1.53
Protein-nucleotide contacts in the immunoglobulin heavy-chain promoter region. Proc Natl Acad Sci U S A (1987) 1.29
Structure of the T15 VH gene subfamily: identification of immunoglobulin gene promotor homologies. J Immunol (1987) 1.04
A conserved heptamer upstream of the IgH promoter region octamer can be the site of a coordinate protein-DNA interaction. Nucleic Acids Res (1988) 1.00
A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal Biochem (1973) 31.32
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res (1989) 22.73
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 20.72
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell (1983) 20.32
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell (1985) 16.46
Novel screening procedure for recombinant plasmids. Science (1977) 12.66
A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs. Nucleic Acids Res (1981) 7.57
Psychotropic drug use and the risk of hip fracture. N Engl J Med (1987) 7.53
An outbreak of Legionnaires' disease associated with a contaminated air-conditioning cooling tower. N Engl J Med (1980) 6.64
Direct transfer of cloned genes from bacteria to mammalian cells. Proc Natl Acad Sci U S A (1980) 6.21
A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene. Nature (1984) 6.05
Molecular analysis of the histone gene cluster of psammechinus miliaris: II. The arrangement of the five histone-coding and spacer sequences. Cell (1976) 5.58
Mass psychogenic illness attributed to toxic exposure at a high school. N Engl J Med (2000) 5.25
Genes and spacers of cloned sea urchin histone DNA analyzed by sequencing. Cell (1978) 5.18
A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells. Nature (1988) 5.16
CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev (1989) 5.00
Innovative communicable disease reporting. HSMHA Health Rep (1971) 4.67
Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer. EMBO J (1987) 4.58
Polyoma virus DNA replication requires an enhancer. Nature (1984) 4.32
Immunization of adults. N Engl J Med (1993) 4.23
The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificity. Genes Dev (1987) 4.20
Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions. EMBO J (1992) 4.05
Transcriptional 'enhancers' from SV40 and polyoma virus show a cell type preference. Nucleic Acids Res (1982) 3.94
Transcriptional activation modulated by homopolymeric glutamine and proline stretches. Science (1994) 3.92
An SV40 "enhancer trap" incorporates exogenous enhancers or generates enhancers from its own sequences. Cell (1984) 3.61
OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts. Nucleic Acids Res (1987) 3.56
A surgeon with AIDS. Lack of evidence of transmission to patients. JAMA (1990) 3.49
OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell (1995) 3.38
Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA). EMBO J (1988) 3.33
Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev (1988) 3.05
Overwhelming strongyloidiasis: an unappreciated opportunistic infection. Medicine (Baltimore) (1978) 2.98
RNA polymerase II C-terminal domain required for enhancer-driven transcription. Nature (1995) 2.78
A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus. Proc Natl Acad Sci U S A (1985) 2.74
Tularemia: a 30-year experience with 88 cases. Medicine (Baltimore) (1985) 2.67
A B-cell coactivator of octamer-binding transcription factors. Nature (1995) 2.67
Letter: Adenovirus type 19 keratoconjunctivitis. N Engl J Med (1974) 2.63
Transmission of tuberculosis in a jail. Ann Intern Med (1999) 2.58
Risk of seizures and encephalopathy after immunization with the diphtheria-tetanus-pertussis vaccine. JAMA (1990) 2.54
Molecular genetic analyses of the Tyrolean Ice Man. Science (1994) 2.53
Improving antibiotic prescribing in office practice. A controlled trial of three educational methods. JAMA (1983) 2.50
Macrolide resistance among invasive Streptococcus pneumoniae isolates. JAMA (2001) 2.40
Transformation of frog embryos with a rabbit beta-globin gene. Proc Natl Acad Sci U S A (1981) 2.37
Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1. Nucleic Acids Res (1996) 2.35
Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter. EMBO J (1993) 2.30
An enhancer stimulates transcription in trans when attached to the promoter via a protein bridge. Cell (1989) 2.30
Metal binding 'finger' structures in the glucocorticoid receptor defined by site-directed mutagenesis. EMBO J (1988) 2.26
Cell-type preference of immunoglobulin kappa and lambda gene promoters. EMBO J (1985) 2.22
Clinical epidemiology of sporadic measles in a highly immunized population. N Engl J Med (1968) 2.22
Insulinotropic action of glucagonlike peptide-I-(7-37) in diabetic and nondiabetic subjects. Diabetes Care (1992) 2.21
The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBO J (1994) 2.19
Eukaryotic expression vectors for the analysis of mutant proteins. Nucleic Acids Res (1989) 2.15
Correct transcription of a cloned mouse immunoglobulin gene in vivo. Proc Natl Acad Sci U S A (1983) 2.14
High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes. Cell (1985) 2.14
Evolution of a plasmid mediating resistance to multiple antimicrobial agents during a prolonged epidemic of nosocomial infections. J Infect Dis (1981) 2.13
Seroepidemiology of hepatitis B in Tennessee prisoners. J Infect Dis (1984) 2.12
A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene. EMBO J (1988) 2.10
B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation. Nature (1996) 2.10
DNA phylogeny of the extinct marsupial wolf. Nature (1989) 2.07
Molecular analysis of the histone gene cluster of Psammechinus miliaris: III. Polarity and asymmetry of the histone-coding sequences. Cell (1976) 2.07
The incidence of hepatitis B in Tennessee prisoners. J Infect Dis (1985) 2.00
Analysis of the transcriptional enhancer effect. Cold Spring Harb Symp Quant Biol (1983) 1.99
Integration of eukaryotic genes for 5S RNA and histone proteins into a phage lambda receptor. Nucleic Acids Res (1976) 1.99
An outbreak of nosocomial infection due to multiply resistant Serratia marcescens: evidence of interhospital spread. J Infect Dis (1976) 1.95
A study of antipsychotic drug use in nursing homes: epidemiologic evidence suggesting misuse. Am J Public Health (1980) 1.94
Molecular analysis of the histone gene cluster of Psammechinus miliaris: I. Fractionation and identification of five individual histone mRNAs. Cell (1976) 1.93
The use and efficacy of child restraint devices. The Tennessee experience, 1982 and 1983. JAMA (1984) 1.90
Mitochondrial DNA sequences from Switzerland reveal striking homogeneity of European populations. Biol Chem Hoppe Seyler (1994) 1.87
Sporadic cases of Legionnaires' disease: the expanding clinical spectrum. Ann Intern Med (1979) 1.85
Enhancer sequences and the regulation of gene transcription. Eur J Biochem (1988) 1.84
How do different transcription factors binding the same DNA sequence sort out their jobs? Trends Genet (1989) 1.83
A novel expression selection approach allows precise mapping of the hepatitis B virus enhancer. Nucleic Acids Res (1985) 1.82
Miniature chest radiograph screening for tuberculosis in jails: a cost-effectiveness analysis. Am J Respir Crit Care Med (2001) 1.81
Sustained transmission of mumps in a highly vaccinated population: assessment of primary vaccine failure and waning vaccine-induced immunity. J Infect Dis (1994) 1.78
Salmonella enteritidis gastroenteritis transmitted by intact chicken eggs. Ann Intern Med (1991) 1.77
Drosophila homoeotic genes encode transcriptional activators similar to mammalian OTF-2. Nature (1988) 1.76
Lysostaphin: an enzymatic approach to staphylococcal disease. I. In vitro studies. Yale J Biol Med (1967) 1.75
Therapeutic and epidemiologic recommendations to reduce the spread of type-I beta-lactamase resistance. Diagn Microbiol Infect Dis (1992) 1.74
Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy. J Infect Dis (1983) 1.72
Ehrlichiosis in a golf-oriented retirement community. N Engl J Med (1995) 1.71
A purine-rich DNA sequence motif present in SV40 and lymphotropic papovavirus binds a lymphoid-specific factor and contributes to enhancer activity in lymphoid cells. Genes Dev (1987) 1.68
Reduction in motor vehicle fatalities associated with an increase in the minimum drinking age. JAMA (1989) 1.68
Simian virus 40 enhancer increases RNA polymerase density within the linked gene. Nature (1985) 1.66
Rhodococcus equi--an increasingly recognized opportunistic pathogen. Report of 12 cases and review of 65 cases in the literature. Am J Clin Pathol (1995) 1.66
Homologous recombination and DNA-end joining reactions in zygotes and early embryos of zebrafish (Danio rerio) and Drosophila melanogaster. Biol Chem (1998) 1.65
Carriage of multidrug-resistant Streptococcus pneumoniae and impact of chemoprophylaxis during an outbreak of meningitis at a day care center. Clin Infect Dis (1999) 1.64
The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation. EMBO J (1996) 1.63
Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1. EMBO J (1998) 1.61
During B-cell differentiation enhancer activity and transcription rate of immunoglobulin heavy chain genes are high before mRNA accumulation. Cell (1986) 1.59