The HSP90 inhibitor ganetespib potentiates the antitumor activity of EGFR tyrosine kinase inhibition in mutant and wild-type non-small cell lung cancer.

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Published in Target Oncol on August 01, 2014

Authors

Donald L Smith1, Jaime Acquaviva, Manuel Sequeira, John-Paul Jimenez, Chaohua Zhang, Jim Sang, Richard C Bates, David A Proia

Author Affiliations

1: Synta Pharmaceuticals Corp, 125 Hartwell Ave, Lexington, MA, 02421, USA.

Associated clinical trials:

Hsp90 Inhibitor AUY922 and Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer | NCT01259089

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