Crystallization and preliminary diffraction studies of Erythrina trypsin inhibitor.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 2511330)

Published in J Mol Biol on November 05, 1989

Authors

S Onesti1, L F Lloyd, D Maeder, A Mistry, P Brick, D Blow, D M Blow

Author Affiliations

1: Imperial College of Science, Technology and Medicine, London, U.K.

Articles by these authors

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP. Nature (1985) 8.46

Hydrogen bonding and biological specificity analysed by protein engineering. Nature (1985) 6.20

Role of a buried acid group in the mechanism of action of chymotrypsin. Nature (1969) 4.36

Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites. Nat Struct Biol (1998) 4.34

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S. EMBO J (1997) 4.20

Three-dimensional structure of tosyl-alpha-chymotrypsin. Nature (1967) 3.57

Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. Structure (1996) 3.51

Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate. J Mol Biol (1989) 3.16

Structure of crystalline -chymotrypsin. V. The atomic structure of tosyl- -chymotrypsin at 2 A resolution. J Mol Biol (1972) 3.09

Specificity of antibodies to immunodominant mycobacterial antigens in pulmonary tuberculosis. J Clin Microbiol (1988) 2.79

Structure of crystalline -chymotrypsin. II. A preliminary report including a hypothesis for the activation mechanism. J Mol Biol (1968) 2.72

Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance. J Bacteriol (2000) 2.41

Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation. Biochemistry (1983) 2.31

Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin. Structure (1996) 2.21

Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1999) 2.11

Structure of alpha-chymotrypsin refined at 1.68 A resolution. J Mol Biol (1985) 2.08

Structure of crystalline alpha-chymotrypsin. 3. Crystallographic studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin. J Mol Biol (1969) 1.87

Structural basis for the inhibition of firefly luciferase by a general anesthetic. Biophys J (1998) 1.83

Crystal structure of the complex of porcine trypsin with soybean trypsin inhibitor (Kunitz) at 2.6-A resolution. Biochemistry (1974) 1.76

Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed by a 1,2-hydride shift. J Mol Biol (1990) 1.74

Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan. Biochemistry (1999) 1.70

Atomic co-ordinates for tosyl-alpha-chymotrypsin. Biochem Biophys Res Commun (1969) 1.67

Structures of D-xylose isomerase from Arthrobacter strain B3728 containing the inhibitors xylitol and D-sorbitol at 2.5 A and 2.3 A resolution, respectively. J Mol Biol (1989) 1.61

Structure of an archaeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex. Mol Cell (2001) 1.56

Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy. Structure (1997) 1.53

The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli. Structure (1995) 1.48

A large increase in enzyme-substrate affinity by protein engineering. Nature (1984) 1.46

Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller. Structure (1995) 1.44

Tyrosyl-tRNA synthetase forms a mononucleotide-binding fold. J Mol Biol (1982) 1.44

X-ray diffraction studies of enzymes. Annu Rev Biochem (1970) 1.42

Fatty acid binding to human serum albumin: new insights from crystallographic studies. Biochim Biophys Acta (1999) 1.42

Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther (2002) 1.36

Influence of the TonB energy-coupling protein on efflux-mediated multidrug resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1998) 1.36

Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by D-xylose isomerase. Proc Natl Acad Sci U S A (1990) 1.33

Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases. Biochemistry (1993) 1.33

Control of nucleation of protein crystals. Protein Sci (1994) 1.32

Enzymology. More of the catalytic triad. Nature (1990) 1.32

Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver. Genes Immun (2011) 1.32

Crystal structure of cholesterol oxidase from Brevibacterium sterolicum refined at 1.8 A resolution. J Mol Biol (1991) 1.31

Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution. J Mol Biol (1994) 1.29

Crystal structure of the anti-fungal target N-myristoyl transferase. Nat Struct Biol (1998) 1.29

Phase diagram and dilution experiments in the crystallization of carboxypeptidase G2. Acta Crystallogr D Biol Crystallogr (1994) 1.26

Cell binding and internalization by filamentous phage displaying a cyclic Arg-Gly-Asp-containing peptide. J Biol Chem (1994) 1.23

A means of promoting heavy-atom binding in protein crystals. J Mol Biol (1965) 1.22

Crystallographic analysis of triclosan bound to enoyl reductase. J Mol Biol (1999) 1.20

MexXY-OprM efflux pump is required for antagonism of aminoglycosides by divalent cations in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2001) 1.19

Active site of lysyl-tRNA synthetase: structural studies of the adenylation reaction. Biochemistry (2000) 1.16

The crystal structure of tyrosyl-transfer RNA synthetase at 2-7 A resolution. J Mol Biol (1976) 1.14

Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine. J Mol Biol (1987) 1.13

The use of x-ray diffraction in the study of protein and nucleic acid structure. Methods Biochem Anal (1965) 1.13

Collagenase: a key enzyme in collagen turnover. Biochem Cell Biol (1996) 1.12

Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX. Gene Ther (2006) 1.10

Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds. J Mol Biol (1991) 1.09

Control of nucleation in the crystallization of lysozyme. Protein Sci (1993) 1.08

An x-ray diffraction study of inhibited derivatives of alpha-chymotrypsin. J Mol Biol (1966) 1.08

Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. A stereochemical interpretation. Biochemistry (1973) 1.08

Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding. Biochemistry (2000) 1.06

Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina. Gene Ther (2003) 1.06

Mode of action of soybean trypsin inhibitor (Kunitz) as a model for specific protein-protein interactions. Nature (1974) 1.05

Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target. Proc Natl Acad Sci U S A (2000) 1.03

-Chymotrypsin: what can we learn about catalysis from x-ray diffraction? Cold Spring Harb Symp Quant Biol (1972) 1.01

Comparison of backbone structures of glucose isomerase from Streptomyces and Arthrobacter. Protein Eng (1987) 0.99

Insights into the molecular basis of thermal stability from the analysis of ion-pair networks in the glutamate dehydrogenase family. Eur J Biochem (1998) 0.99

The study of alpha-chymotrypsin by x-ray diffraction. The Third CIBA Medal Lecture. Biochem J (1969) 0.98

Structural homology in the amino-terminal domains of two aminoacyl-tRNA synthetases. J Mol Biol (1983) 0.97

Molecular mechanics simulations of a conformational rearrangement of D-xylose in the active site of D-xylose isomerase. Proteins (1992) 0.94

I. Serine proteinases. The structure of alpha-chymotrypsin. Philos Trans R Soc Lond B Biol Sci (1970) 0.94

Identification and characterization of a DNA primase from the hyperthermophilic archaeon Methanococcus jannaschii. Nucleic Acids Res (1999) 0.92

Extension growth of Impatiens glandulifera at low irradiance: importance of nitrate and potassium accumulation. Ann Bot (2005) 0.90

Crystallization and preliminary diffraction studies of firefly luciferase from Photinus pyralis. Acta Crystallogr D Biol Crystallogr (1996) 0.89

Purification and characterization of the herpes simplex virus type 1 ribonucleotide reductase small subunit following expression in Escherichia coli. J Gen Virol (1991) 0.89

Amino acid activation in crystalline tyrosyl-tRNA synthetase from Bacillus stearothermophilus. J Mol Biol (1981) 0.88

Interaction of crystalline tyrosyl-tRNA synthetase with adenosine, adenosine monophosphate, adenosine triphosphate and pyrophosphate in the presence of tyrosinol. J Mol Biol (1984) 0.87

Structure of a mutant of tyrosyl-tRNA synthetase with enhanced catalytic properties. Nature (1987) 0.85

Crystals of Escherichia coli single-strand DNA-binding protein show that the tetramer has D2 symmetry. J Mol Biol (1983) 0.85

Transfection-free and scalable recombinant AAV vector production using HSV/AAV hybrids. Gene Ther (2004) 0.85

A model for the association of bovine pancreatic trypsin inhibitor with chymotrypsin and trypsin. J Mol Biol (1972) 0.83

Letter: Crystallization and preliminary x-ray diffraction studies on tyrosyl-transfer RNA synthetase from Bacillus stearothermophilus. J Mol Biol (1973) 0.83

Anomeric specificity of D-xylose isomerase. Biochemistry (1992) 0.83

Binding of tyrosine, adenosine triphosphate and analogues to crystalline tyrosyl transfer RNA synthetase. J Mol Biol (1978) 0.82

Crystallographic studies of protein-nucleic acid interaction: catabolite gene activator protein and the large fragment of DNA polymerase I. J Biomol Struct Dyn (1983) 0.81

Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization. Gene Ther (2003) 0.81

Enzymology. Lipases reach the surface. Nature (1991) 0.81

The peptide chain of tyrosyl tRNA synthetase: no evidence for a super-secondary structure of four alpha-helices. Biochem Biophys Res Commun (1977) 0.80

Arthrobacter D-xylose isomerase: protein-engineered subunit interfaces. Biochem J (1993) 0.80

Many crystal forms of human immunodeficiency virus reverse transcriptase. J Mol Biol (1991) 0.80

Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator. Acta Crystallogr D Biol Crystallogr (1998) 0.79