Published in MBio on August 12, 2014
Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model. Antimicrob Agents Chemother (2015) 0.82
Disease tolerance and immunity in host protection against infection. Nat Rev Immunol (2017) 0.80
A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. FEBS J (2016) 0.79
Neural Inhibition of Dopaminergic Signaling Enhances Immunity in a Cell-Non-autonomous Manner. Curr Biol (2016) 0.77
The immune response and antibacterial therapy. Med Microbiol Immunol (2014) 0.76
Effects of methyl and inorganic mercury exposure on genome homeostasis and mitochondrial function in Caenorhabditis elegans. DNA Repair (Amst) (2017) 0.75
A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors. PLoS One (2016) 0.75
Beyond Traditional Antimicrobials: A Caenorhabditis elegans Model for Discovery of Novel Anti-infectives. Front Microbiol (2016) 0.75
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J Clin Microbiol (2000) 34.08
Innate immune recognition. Annu Rev Immunol (2001) 26.65
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature (1997) 13.09
Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections. Lancet Infect Dis (2006) 7.36
A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science (2002) 5.97
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell (2008) 5.60
Diagnosing the decline in pharmaceutical R&D efficiency. Nat Rev Drug Discov (2012) 5.55
Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci U S A (1999) 5.10
Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science (2003) 4.91
A simple model host for identifying Gram-positive virulence factors. Proc Natl Acad Sci U S A (2001) 4.69
p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet (2006) 4.47
Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA (2003) 4.31
In vivo comparison of avirulent Vwa- and Pgm- or Pstr phenotypes of yersiniae. Infect Immun (1984) 4.16
Generation of restriction map of Enterococcus faecalis OG1 and investigation of growth requirements and regions encoding biosynthetic function. J Bacteriol (1993) 4.14
Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses. Cell (2012) 2.81
Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Science (2011) 2.59
Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat Rev Immunol (2010) 2.45
Traversing the valley of death: a guide to assessing prospects for translational success. Sci Transl Med (2009) 1.81
Caenorhabditis elegans as a host for the study of host-pathogen interactions. Curr Opin Microbiol (2002) 1.75
Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity. Proc Natl Acad Sci U S A (2006) 1.68
Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans. PLoS Pathog (2011) 1.59
Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans. PLoS Genet (2010) 1.55
Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans. Cell Host Microbe (2009) 1.53
GATA transcription factor required for immunity to bacterial and fungal pathogens. PLoS One (2006) 1.38
High-throughput screening and small animal models, where are we? Br J Pharmacol (2010) 1.37
Xenobiotic detoxification in the nematode Caenorhabditis elegans. J Exp Zool A Comp Exp Biol (2006) 1.36
Immunomodulatory properties of antibiotics. Curr Mol Pharmacol (2008) 1.25
A conserved PMK-1/p38 MAPK is required in caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection. J Biol Chem (2010) 1.22
Antibiotic susceptibilities of 94 isolates of Yersinia pestis to 24 antimicrobial agents. J Antimicrob Chemother (2003) 1.09
Yersinia pestis kills Caenorhabditis elegans by a biofilm-independent process that involves novel virulence factors. EMBO Rep (2005) 1.06
Immunomodulatory activity and effectiveness of macrolides in chronic airway disease. Chest (2004) 1.05
Role of the nervous system in the control of proteostasis during innate immune activation: insights from C. elegans. PLoS Pathog (2013) 0.92
Identification of highly active Fe sites in (Ni,Fe)OOH for electrocatalytic water splitting. J Am Chem Soc (2015) 1.40
The emergence of clinical resistance to tigecycline. Int J Antimicrob Agents (2012) 1.35
Core-protected platinum monolayer shell high-stability electrocatalysts for fuel-cell cathodes. Angew Chem Int Ed Engl (2010) 1.34
An approach to studying lung cancer-related proteins in human blood. Mol Cell Proteomics (2005) 1.25
Different immunoaffinity fractionation strategies to characterize the human plasma proteome. J Proteome Res (2006) 1.23
A dataset of human fetal liver proteome identified by subcellular fractionation and multiple protein separation and identification technology. Mol Cell Proteomics (2006) 1.04
A strategy for precise and large scale identification of core fucosylated glycoproteins. Mol Cell Proteomics (2009) 1.03
In vitro bactericidal activity of allicin combined with cefoperazone, tobramycin and ciprofloxacin. Int J Antimicrob Agents (2007) 1.03
Mutant prevention concentration-based pharmacokinetic/pharmacodynamic indices as dosing targets for suppressing the enrichment of levofloxacin-resistant subpopulations of Staphylococcus aureus. Antimicrob Agents Chemother (2011) 1.02
Phosphoproteome analysis of the human Chang liver cells using SCX and a complementary mass spectrometric strategy. Proteomics (2008) 0.99
Inhibition of increased circulating Tfh cell by anti-CD20 monoclonal antibody in patients with type 1 diabetes. PLoS One (2013) 0.98
Allicin enhances the oxidative damage effect of amphotericin B against Candida albicans. Int J Antimicrob Agents (2008) 0.97
Effect of RNA interference of iASPP on the apoptosis in MCF-7 breast cancer cells. Cancer Invest (2008) 0.96
Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells. Proteomics (2008) 0.96
Comparison of alternative analytical techniques for the characterisation of the human serum proteome in HUPO Plasma Proteome Project. Proteomics (2005) 0.94
Highly stable Pt monolayer on PdAu nanoparticle electrocatalysts for the oxygen reduction reaction. Nat Commun (2012) 0.92
Antibacterial activity of allicin alone and in combination with beta-lactams against Staphylococcus spp. and Pseudomonas aeruginosa. J Antibiot (Tokyo) (2007) 0.92
The cardiotoxicity of macrolides: a systematic review. Pharmazie (2010) 0.91
On the origin of the unique properties of supported Au nanoparticles. J Am Chem Soc (2006) 0.89
Proteomic analysis on structural proteins of Severe Acute Respiratory Syndrome coronavirus. Proteomics (2004) 0.89
Identification of degradation products formed during performic oxidation of peptides and proteins by high-performance liquid chromatography with matrix-assisted laser desorption/ionization and tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.86
Proteomics-based generation and characterization of monoclonal antibodies against human liver mitochondrial proteins. Proteomics (2006) 0.86
Analysis of human liver proteome using replicate shotgun strategy. Proteomics (2007) 0.86
Phosphopeptide detection using automated online IMAC-capillary LC-ESI-MS/MS. Proteomics (2006) 0.86
An efficient method for dephosphorylation of phosphopeptides by cerium oxide. J Mass Spectrom (2008) 0.85
[Effects of lactone I from Atractylodes macrocephala Koidz on cytokines and proteolysis-inducing factors in cachectic cancer patients]. Di Yi Jun Yi Da Xue Xue Bao (2005) 0.84
Non-gel-based dual 18O labeling quantitative proteomics strategy. Anal Chem (2007) 0.83
Method for quantitative proteomics research by using metal element chelated tags coupled with mass spectrometry. Anal Chem (2006) 0.83
Phosphoproteome profile of human liver Chang's cell based on 2-DE with fluorescence staining and MALDI-TOF/TOF-MS. Electrophoresis (2007) 0.83
Trypsin immobilization on hairy polymer chains hybrid magnetic nanoparticles for ultra fast, highly efficient proteome digestion, facile 18O labeling and absolute protein quantification. Anal Chem (2012) 0.82
Enrichment of phosphopeptides by Fe3+-immobilized magnetic nanoparticles for phosphoproteome analysis of the plasma membrane of mouse liver. J Proteome Res (2008) 0.80
In vitro activity of two old antibiotics against clinical isolates of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo) (2010) 0.79
Mutant prevention concentration of colistin alone and in combination with levofloxacin or tobramycin against multidrug-resistant Acinetobacter baumannii. Int J Antimicrob Agents (2012) 0.79
Equilibrium and kinetic studies of phosphate removal from solution onto a hydrothermally modified oyster shell material. PLoS One (2013) 0.79
Psychological status and diabetes-related distress of Chinese type 1 diabetes patients in Jiangsu province, China. J Biomed Res (2013) 0.78
Androgen receptor CpG island methylation status in human leukemia cancer cells. Cancer Invest (2009) 0.78
Enzymatic synthesis of alpha-glucosyl-timosaponin BII catalyzed by the extremely thermophilic enzyme: Toruzyme 3.0L. Carbohydr Res (2010) 0.78
Proteome analysis on an early transformed human bronchial epithelial cell line, BEP2D, after alpha-particle irradiation. Proteomics (2003) 0.78
Mycoplasma pneumoniae infection is associated with subacute cough. Eur Respir J (2013) 0.78
A new strategy to resume the apoptosis activity of p53 in leukemia cell lines retaining wild-type p53. Leuk Res (2006) 0.77
Activated platelets interact with lung cancer cells through P-selectin glycoprotein ligand-1. Pathol Oncol Res (2012) 0.77
[Effect of bone marrow mesenchymal stem cell infusion on hemato-poiesis in mice with aplastic anemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2007) 0.77
[Enrichment strategy of cysteine-containing peptides based on covalent chromatography]. Se Pu (2010) 0.77
[A randomized clinical study on efficacy of Aidi injection combined with chemotherapy in the treatment of advanced non-small cell lung cancer]. Zhongguo Fei Ai Za Zhi (2004) 0.77
Surface glycoproteomic analysis of hepatocellular carcinoma cells by affinity enrichment and mass spectrometric identification. Glycoconj J (2012) 0.77
A systematic N-terminal peptide quantitative labeling strategy for differential proteomic analysis. Proteomics Clin Appl (2010) 0.77
Multiplex single-nucleotide polymorphism genotyping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Biochem (2003) 0.77
Modified enzyme-linked immunosorbent assay strategy using graphene oxide sheets and gold nanoparticles functionalized with different antibody types. Anal Chem (2013) 0.77
Blast effect on the lower extremities and its mitigation: a computational study. J Mech Behav Biomed Mater (2013) 0.77
Design of Pt-Pd binary superlattices exploiting shape effects and synergistic effects for oxygen reduction reactions. J Am Chem Soc (2012) 0.77
Dual matrix-based immobilized trypsin for complementary proteolytic digestion and fast proteomics analysis with higher protein sequence coverage. Anal Chem (2014) 0.77
[BMP-4 and VEGF promote development of hematopoietic stem cells during the embryoid body formation from embryonic stem cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2008) 0.77
Treatment of community-acquired pneumonia with moxifloxacin: a meta-analysis of randomized controlled trials. J Chemother (2012) 0.77
Enrichment and identification of cysteine-containing peptides from tryptic digests of performic oxidized proteins by strong cation exchange LC and MALDI-TOF/TOF MS. Anal Chem (2005) 0.76
A sensitive dual signal amplification method for western blotting based on antibody-functionalised graphene oxide and gold nanoparticles. Analyst (2012) 0.76
Quantification of sifuvirtide in monkey plasma by an on-line solid-phase extraction procedure combined with liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.76
Human cytomegalovirus induces caspase-dependent apoptosis of megakaryocytic CHRF-288-11 cells by activating the JNK pathway. Int J Hematol (2010) 0.76
In vitro activity of minocycline combined with fosfomycin against clinical isolates of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo) (2011) 0.75
Site-specific qualitative and quantitative analysis of the N- and O-glycoforms in recombinant human erythropoietin. Anal Bioanal Chem (2014) 0.75
Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals. Medicine (Baltimore) (2016) 0.75
Determination of thalidomide concentration in human plasma by liquid chromatography-tandem mass spectrometry. Exp Ther Med (2012) 0.75
A method for rapidly confirming protein N-terminal sequences by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom (2006) 0.75
[Biological characteristics of bone marrow-derived mesenchymal stem cells and their relationship with immunosuppressive therapy in children with aplastic anemia]. Zhongguo Dang Dai Er Ke Za Zhi (2008) 0.75
Development and validation of a highly sensitive LC-MS/MS method for quantitation of bivalirudin in human plasma: application to a human pharmacokinetic study. Biomed Chromatogr (2013) 0.75
[Experiment study of efficacy on hematopoietic reconstitution and GVHD prophylaxis after mesenchymal cell infused by intra-bone marrow cavity or intravenous in rat BMT models]. Zhonghua Xue Ye Xue Za Zhi (2007) 0.75
[Application of aspartic acid as a non-specific binding inhibitor in the enrichment of phosphopeptides with titanium dioxide]. Se Pu (2010) 0.75
[Supportive effects of stromal cells from human embryonic aorta-gonad-mesonephros region on umbilical cord blood CD34+ cells]. Zhonghua Xue Ye Xue Za Zhi (2006) 0.75
[Cleavage of amide bond during glycopeptide enrichment using wheat germ agglutinin affinity chromatography]. Se Pu (2009) 0.75
[Application of multiplex ligation-dependent probe amplification technique in prenatal diagnosis of α-thalassemia]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi (2015) 0.75
Toward a high resolution 2-DE profile of the normal human liver proteome using ultra-zoom gels. Sci China Life Sci (2011) 0.75
Highly efficient enrichment of phosphopeptides by magnetic nanoparticles coated with zirconium phosphonate for phosphoproteome analysis. Rapid Commun Mass Spectrom (2008) 0.75
[Pamidronate in treatment of pain caused by bone metastasis]. Ai Zheng (2004) 0.75
Tigecycline: benefits and risks. Lancet Infect Dis (2011) 0.75
Using cross-correlation normalized for peptide length to optimize peptide identification in shotgun proteomics. Rapid Commun Mass Spectrom (2005) 0.75
High-throughput absolute quantification of proteins using an improved two-dimensional reversed-phase separation and quantification concatemer (QconCAT) approach. Anal Bioanal Chem (2014) 0.75
Islet neogenesis-associated protein-related pentadecapeptide improves the function of allograft after islets transplantation. J Pediatr Endocrinol Metab (2014) 0.75
[Inhibitory activities of 3-trifluoromethyl benzamide derivatives against the entry of H5N1 influenza viruses]. Nan Fang Yi Ke Da Xue Xue Bao (2014) 0.75
Construction of a full-length iASPP expression plasmid pcDNA3.1+/iASPP and its biological activity. Plasmid (2009) 0.75
[Correlation between facial nerve functional evaluation and efficacy evaluation of acupuncture treatment for Bell's palsy]. Zhong Xi Yi Jie He Xue Bao (2012) 0.75
[Preparation of grapheme oxide based immobilized lectin and its application to efficient glycoprotein/glycopeptide enrichment]. Se Pu (2015) 0.75
[A novel immobilized trypsin on hydrophilic polymer modified Silica beads for proteome characterization]. Se Pu (2013) 0.75
[Human cytomegalovirus aggravates apoptosis of human megakaryocytes via direct infection in vitro]. Zhongguo Shi Yan Xue Ye Xue Za Zhi (2004) 0.75
[Studies on relationship between peak capacity and column length for separation of peptides by high performance liquid chromatography]. Se Pu (2004) 0.75
Pharmacokinetic/pharmacodynamic research on three different infusion time regimens of linezolid in healthy Chinese volunteers. Int J Clin Pharmacol Ther (2015) 0.75
[New advances of high performance separation and analytical techniques for proteins in complex biological systems]. Se Pu (2005) 0.75
Quantitative and morphological study of intraepidermal nerve fibre in healthy individuals. Neurol Res (2015) 0.75
Heterogeneous catalysts need not be so "heterogeneous": monodisperse Pt nanocrystals by combining shape-controlled synthesis and purification by colloidal recrystallization. J Am Chem Soc (2013) 0.75
[Phosphopeptide enrichment strategy based on strong cation exchange chromatography]. Se Pu (2008) 0.75
[The relationship between career decision-making self efficacy and anxiety]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi (2012) 0.75
[Relation between Chinese Medical Constitutions and Chemotherapy-induced Leucopenia in Breast Cancer Patients: a Clinical Study]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2015) 0.75
CpG islands aberrant hypermethylation of sex hormone receptor superfamily might be involved in the development of leukemic neoplasms. Leuk Res (2010) 0.75
Specific capture of phosphopeptides on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry targets modified by magnetic affinity nanoparticles. Rapid Commun Mass Spectrom (2007) 0.75
[Separation of peptides using off-line pH gradient-strong cation exchange chromatography]. Se Pu (2007) 0.75
Physical Activity Outcomes of Nurse-Delivered Lifestyle Interventions. Home Healthc Now (2016) 0.75
A simple and efficient frit preparation method for one-end tapered-fused silica-packed capillary columns in nano-LC-ESI MS. Proteomics (2010) 0.75
[Analysis of protein phosphorylation by combination of IMAC, phosphatase with biological mass spectrometry]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) (2003) 0.75
Toxicological effects of multi-walled carbon nanotubes adsorbed with nonylphenol on earthworm Eisenia fetida. Environ Sci Process Impacts (2013) 0.75
[Correlation between plasma leptin level and premature infant weight loss]. Zhonghua Er Ke Za Zhi (2004) 0.75
How Exercise Influences Cognitive Performance When Mild Cognitive Impairment Exists: A Literature Review. J Psychosoc Nurs Ment Health Serv (2015) 0.75