Published in PLoS One on August 21, 2014
Brown adipose tissue: function and physiological significance. Physiol Rev (2004) 23.00
Central nervous system control of food intake. Nature (2000) 15.85
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature (1994) 7.86
Obesity-induced inflammatory changes in adipose tissue. J Clin Invest (2003) 7.50
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab (2001) 5.76
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest (2012) 4.01
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. Nat Med (2006) 3.11
beta(3)-adrenergic stimulation differentially inhibits insulin signaling and decreases insulin-induced glucose uptake in brown adipocytes. J Biol Chem (1999) 2.13
Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. Am J Physiol (1986) 2.01
Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis. Cytokine (2008) 1.95
beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase. J Biol Chem (2001) 1.89
Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J (1991) 1.82
Leptin increases uncoupling protein expression and energy expenditure. Am J Physiol (1997) 1.55
Leptin-induced signal transduction pathways. Cell Biol Int (2004) 1.53
gp130 receptor ligands as potential therapeutic targets for obesity. J Clin Invest (2007) 1.46
Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. FASEB J (2002) 1.44
Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. Osteoarthritis Cartilage (2012) 1.40
Murine models for pharmacological studies of the metabolic syndrome. Pharmacol Ther (2012) 1.34
Hyperphagia and obesity in OLETF rats lacking CCK-1 receptors. Philos Trans R Soc Lond B Biol Sci (2006) 1.30
Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression. Gut (2010) 1.30
GM-CSF action in the CNS decreases food intake and body weight. J Clin Invest (2005) 1.23
Cancer cachexia--pathophysiology and management. J Gastroenterol (2013) 1.20
Differential body weight and feeding responses to high-fat diets in rats and mice lacking cholecystokinin 1 receptors. Am J Physiol Regul Integr Comp Physiol (2007) 1.18
Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice. Am J Physiol (1997) 1.18
Phylogeny and evolution of class-I helical cytokines. J Endocrinol (2006) 1.11
The polymorphisms of UCP1 genes associated with fat metabolism, obesity and diabetes. Mol Biol Rep (2009) 1.10
Selective activation of STAT3 in human monocytes stimulated by G-CSF: implication in inhibition of LPS-induced TNF-alpha production. Am J Physiol Cell Physiol (2004) 1.02
Metabolic remodeling in adipocytes promotes ciliary neurotrophic factor-mediated fat loss in obesity. Endocrinology (2008) 1.02
Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice. Diabetes (2004) 1.01
Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia. J Infect Dis (2004) 1.00
gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor. Proc Natl Acad Sci U S A (2006) 0.99
Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods. Peptides (2002) 0.98
Development of obesity in the Otsuka Long-Evans Tokushima Fatty rat. Am J Physiol Regul Integr Comp Physiol (2009) 0.96
The granulocyte colony stimulating factor (G-CSF) activates Jak/STAT and MAPK pathways in a trophoblastic cell line. J Cell Biochem (2008) 0.94
TNF-alpha inhibits UCP-1 expression in brown adipocytes via ERKs. Opposite effect of p38MAPK. FEBS Lett (2001) 0.93
The gp130 receptor cytokine family: regulators of adipocyte development and function. Curr Pharm Des (2011) 0.92
Involvement of PTP-RQ in differentiation during adipogenesis of human mesenchymal stem cells. Biochem Biophys Res Commun (2009) 0.92
The role of the uncoupling protein 1 (UCP1) on the development of obesity and type 2 diabetes mellitus. Arq Bras Endocrinol Metabol (2012) 0.91
Genetic dissection of "OLETF", a rat model for non-insulin-dependent diabetes mellitus. Mamm Genome (1998) 0.89
Endothelial cell apoptosis in brown adipose tissue of rats induced by hyperinsulinaemia: the possible role of TNF-α. Eur J Histochem (2011) 0.87
The anorexigenic cytokine ciliary neurotrophic factor stimulates POMC gene expression via receptors localized in the nucleus of arcuate neurons. Am J Physiol Endocrinol Metab (2011) 0.85
G-CSF prevents progression of diabetic nephropathy in rat. PLoS One (2013) 0.83
TNF-alpha induces apoptosis in rat fetal brown adipocytes in primary culture. FEBS Lett (1997) 0.83
Pharmacokinetics of recombinant human granulocyte colony-stimulating factor in the rat. Single and multiple dosing studies. Drug Metab Dispos (1991) 0.83
Direct effects of ciliary neurotrophic factor on brown adipocytes: evidence for a role in peripheral regulation of energy homeostasis. J Endocrinol (2002) 0.82
Effects of granulocyte-colony stimulating factor (G-CSF) on diabetic cardiomyopathy in Otsuka Long-Evans Tokushima fatty rats. Cardiovasc Diabetol (2011) 0.80
Therapeutic effects of granulocyte-colony stimulating factor on non-alcoholic hepatic steatosis in the rat. Ann Hepatol (2013) 0.79
Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. PLoS One (2013) 0.77
Insulin and glucagon secretions, and morphological change of pancreatic islets in OLETF rats, a model of type 2 diabetes mellitus. J Korean Med Sci (2002) 0.76
Transplanted Human Amniotic Epithelial Cells Secrete Paracrine Proangiogenic Cytokines in Rat Model of Myocardial Infarction. Cell Transplant (2014) 0.77
The Effects of Granulocyte-Colony Stimulating Factor on Regeneration in Nerve Crush Injuries in Rats. Neurochem Res (2016) 0.76
Granulocyte-colony stimulating factor prevents the development of hepatic steatosis in rats. Ann Hepatol (2015) 0.75