Genetic dissection of "OLETF", a rat model for non-insulin-dependent diabetes mellitus.

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Published in Mamm Genome on June 01, 1998

Authors

N Kanemoto1, H Hishigaki, A Miyakita, K Oga, S Okuno, A Tsuji, T Takagi, E Takahashi, Y Nakamura, T K Watanabe

Author Affiliations

1: Otsuka GEN Research Institute, Otsuka Pharmaceutical Co., Ltd., 463-10, Kagasuno, Kawauchi-cho, Tokushima 771-01, Japan.

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Toward information extraction: identifying protein names from biological papers. Pac Symp Biocomput (1998) 8.17

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Quantum computers. Nature (2010) 6.79

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When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain (1995) 5.97

mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev (1997) 5.77

The genetic structure of natural populations of Drosophila melanogaster. XII. Linkage disequilibrium in a large local population. Genetics (1974) 5.72

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Allelotype of colorectal carcinomas. Science (1989) 5.54

The action of tetrodotoxin on electrogenic components of squid giant axons. J Gen Physiol (1965) 5.42

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Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet (1994) 3.39

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IL-6 is produced by osteoblasts and induces bone resorption. J Immunol (1990) 3.14

Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA. A primitive form of plant mitochondrial genome. J Mol Biol (1992) 3.11

PNAD-CSS: a workbench for constructing a protein name abbreviation dictionary. Bioinformatics (2000) 2.98

Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome. Am J Hum Genet (1988) 2.97

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Assessment of prediction accuracy of protein function from protein--protein interaction data. Yeast (2001) 2.90

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Mating preference and the direction of evolution in Drosophila. Science (1979) 2.72

Requirement of CD9 on the egg plasma membrane for fertilization. Science (2000) 2.65

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Mutations of the APC (adenomatous polyposis coli) gene. Hum Mutat (1993) 2.63

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Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res (1990) 2.57

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Virus associated with S.M.O.N. in Japan. Lancet (1971) 2.19

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